Gene Gene information from NCBI Gene database.
Entrez ID 144404
Gene name Transmembrane protein 120B
Gene symbol TMEM120B
Synonyms (NCBI Gene)
-
Chromosome 12
Chromosome location 12q24.31
miRNA miRNA information provided by mirtarbase database.
1163
miRTarBase ID miRNA Experiments Reference
MIRT047879 hsa-miR-30c-5p CLASH 23622248
MIRT043357 hsa-miR-331-3p CLASH 23622248
MIRT039006 hsa-miR-766-3p CLASH 23622248
MIRT037056 hsa-miR-877-3p CLASH 23622248
MIRT037056 hsa-miR-877-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0005216 Function Monoatomic ion channel activity ISS
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005634 Component Nucleus IEA
GO:0005637 Component Nuclear inner membrane IBA
GO:0005637 Component Nuclear inner membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616551 32008 ENSG00000188735
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0PK00
Protein name Transmembrane protein 120B
Protein function Necessary for efficient adipogenesis. Does not show ion channel activity.
PDB 7F73
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07851 TMPIT 9 332 TMPIT-like protein Family
Sequence
Sequence length 339
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Exstrophy-epispadias complex Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OMPHALOCELE EXSTROPHY IMPERFORATE ANUS Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma Squamous Cell Squamous cell carcinoma Pubtator 35768804 Associate
★☆☆☆☆
Found in Text Mining only
Glaucoma Open Angle Open angle glaucoma Pubtator 29847670 Associate
★☆☆☆☆
Found in Text Mining only
Polycystic Ovary Syndrome Polycystic Ovary Syndrome BEFREE 30075721
★☆☆☆☆
Found in Text Mining only
Polycystic Ovary Syndrome Polycystic ovary syndrome Pubtator 30075721 Associate
★☆☆☆☆
Found in Text Mining only