Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	143282
Gene name	Fibroblast growth factor binding protein 3
Gene symbol	FGFBP3
Synonyms (NCBI Gene)	C10orf13FGF-BP3
Chromosome	10
Chromosome location	10q23.32

265

Show/Hide all (265)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018530	hsa-miR-335-5p	Microarray	18185580
MIRT042123	hsa-miR-484	CLASH	23622248
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT664078	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT664077	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT664078	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT664077	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT620379	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT620377	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT620378	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT620375	hsa-miR-5690	HITS-CLIP	23824327
MIRT620376	hsa-miR-7977	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT614389	hsa-miR-8485	HITS-CLIP	23824327
MIRT614388	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614387	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614386	hsa-miR-603	HITS-CLIP	23824327
MIRT614385	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT614384	hsa-miR-4729	HITS-CLIP	23824327
MIRT614383	hsa-miR-3941	HITS-CLIP	23824327
MIRT614382	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT614381	hsa-miR-6083	HITS-CLIP	23824327
MIRT995891	hsa-miR-1203	CLIP-seq
MIRT995892	hsa-miR-1237	CLIP-seq
MIRT995893	hsa-miR-1248	CLIP-seq
MIRT995894	hsa-miR-1827	CLIP-seq
MIRT995895	hsa-miR-19a	CLIP-seq
MIRT995896	hsa-miR-19b	CLIP-seq
MIRT995897	hsa-miR-2467-3p	CLIP-seq
MIRT995898	hsa-miR-298	CLIP-seq
MIRT995899	hsa-miR-3614-5p	CLIP-seq
MIRT995900	hsa-miR-3662	CLIP-seq
MIRT995901	hsa-miR-3672	CLIP-seq
MIRT995902	hsa-miR-3921	CLIP-seq
MIRT995903	hsa-miR-3925-5p	CLIP-seq
MIRT995904	hsa-miR-3929	CLIP-seq
MIRT995905	hsa-miR-4251	CLIP-seq
MIRT995906	hsa-miR-4311	CLIP-seq
MIRT995907	hsa-miR-4329	CLIP-seq
MIRT995908	hsa-miR-4419b	CLIP-seq
MIRT995909	hsa-miR-4463	CLIP-seq
MIRT995910	hsa-miR-4469	CLIP-seq
MIRT995911	hsa-miR-4478	CLIP-seq
MIRT995912	hsa-miR-4522	CLIP-seq
MIRT995913	hsa-miR-4649-3p	CLIP-seq
MIRT995914	hsa-miR-4653-5p	CLIP-seq
MIRT995915	hsa-miR-4698	CLIP-seq
MIRT995916	hsa-miR-4714-5p	CLIP-seq
MIRT995917	hsa-miR-4799-5p	CLIP-seq
MIRT995918	hsa-miR-485-5p	CLIP-seq
MIRT995919	hsa-miR-569	CLIP-seq
MIRT995920	hsa-miR-589	CLIP-seq
MIRT995921	hsa-miR-642a	CLIP-seq
MIRT1995329	hsa-miR-1243	CLIP-seq
MIRT1995330	hsa-miR-1299	CLIP-seq
MIRT1995331	hsa-miR-136	CLIP-seq
MIRT1995332	hsa-miR-2114	CLIP-seq
MIRT1995333	hsa-miR-3123	CLIP-seq
MIRT1995334	hsa-miR-34b	CLIP-seq
MIRT1995335	hsa-miR-3612	CLIP-seq
MIRT1995336	hsa-miR-3653	CLIP-seq
MIRT1995337	hsa-miR-3654	CLIP-seq
MIRT1995338	hsa-miR-3658	CLIP-seq
MIRT1995339	hsa-miR-3975	CLIP-seq
MIRT995906	hsa-miR-4311	CLIP-seq
MIRT1995340	hsa-miR-4426	CLIP-seq
MIRT1995341	hsa-miR-4443	CLIP-seq
MIRT1995342	hsa-miR-4511	CLIP-seq
MIRT1995343	hsa-miR-4540	CLIP-seq
MIRT1995344	hsa-miR-4647	CLIP-seq
MIRT1995345	hsa-miR-4662b	CLIP-seq
MIRT1995346	hsa-miR-4733-5p	CLIP-seq
MIRT1995347	hsa-miR-4756-3p	CLIP-seq
MIRT1995348	hsa-miR-4778-5p	CLIP-seq
MIRT1995349	hsa-miR-4782-5p	CLIP-seq
MIRT1995350	hsa-miR-4794	CLIP-seq
MIRT1995351	hsa-miR-515-5p	CLIP-seq
MIRT1995352	hsa-miR-516b	CLIP-seq
MIRT1995353	hsa-miR-548b-3p	CLIP-seq
MIRT1995354	hsa-miR-576-3p	CLIP-seq
MIRT1995355	hsa-miR-650	CLIP-seq
MIRT995892	hsa-miR-1237	CLIP-seq
MIRT995893	hsa-miR-1248	CLIP-seq
MIRT1995332	hsa-miR-2114	CLIP-seq
MIRT2229409	hsa-miR-25	CLIP-seq
MIRT995898	hsa-miR-298	CLIP-seq
MIRT2229410	hsa-miR-302f	CLIP-seq
MIRT2229411	hsa-miR-3120-5p	CLIP-seq
MIRT2229412	hsa-miR-32	CLIP-seq
MIRT2229413	hsa-miR-363	CLIP-seq
MIRT2229414	hsa-miR-367	CLIP-seq
MIRT2229415	hsa-miR-3925-3p	CLIP-seq
MIRT2229416	hsa-miR-4272	CLIP-seq
MIRT2229417	hsa-miR-4313	CLIP-seq
MIRT2229418	hsa-miR-4418	CLIP-seq
MIRT2229419	hsa-miR-4446-5p	CLIP-seq
MIRT2229420	hsa-miR-4652-3p	CLIP-seq
MIRT1995349	hsa-miR-4782-5p	CLIP-seq
MIRT995917	hsa-miR-4799-5p	CLIP-seq
MIRT2229421	hsa-miR-509-3-5p	CLIP-seq
MIRT2229422	hsa-miR-509-5p	CLIP-seq
MIRT2229423	hsa-miR-511	CLIP-seq
MIRT2229424	hsa-miR-622	CLIP-seq
MIRT2229425	hsa-miR-767-5p	CLIP-seq
MIRT2229426	hsa-miR-92a	CLIP-seq
MIRT2229427	hsa-miR-92b	CLIP-seq
MIRT2533132	hsa-miR-10a	CLIP-seq
MIRT2533133	hsa-miR-10b	CLIP-seq
MIRT2533134	hsa-miR-142-5p	CLIP-seq
MIRT1995332	hsa-miR-2114	CLIP-seq
MIRT2533135	hsa-miR-339-5p	CLIP-seq
MIRT2533136	hsa-miR-3613-3p	CLIP-seq
MIRT2533137	hsa-miR-3667-5p	CLIP-seq
MIRT2533138	hsa-miR-371-5p	CLIP-seq
MIRT2533139	hsa-miR-371b-5p	CLIP-seq
MIRT2533140	hsa-miR-4421	CLIP-seq
MIRT2533141	hsa-miR-4725-5p	CLIP-seq
MIRT2533142	hsa-miR-504	CLIP-seq
MIRT2533143	hsa-miR-548c-3p	CLIP-seq
MIRT2533132	hsa-miR-10a	CLIP-seq
MIRT2533133	hsa-miR-10b	CLIP-seq
MIRT1995332	hsa-miR-2114	CLIP-seq
MIRT2533135	hsa-miR-339-5p	CLIP-seq
MIRT2533136	hsa-miR-3613-3p	CLIP-seq
MIRT2533137	hsa-miR-3667-5p	CLIP-seq
MIRT2533138	hsa-miR-371-5p	CLIP-seq
MIRT2533139	hsa-miR-371b-5p	CLIP-seq
MIRT2533140	hsa-miR-4421	CLIP-seq
MIRT2533141	hsa-miR-4725-5p	CLIP-seq
MIRT2533142	hsa-miR-504	CLIP-seq
MIRT2533143	hsa-miR-548c-3p	CLIP-seq

Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	IDA	18669637
GO:0005576	Component	Extracellular region	IEA
GO:0007267	Process	Cell-cell signaling	IBA
GO:0008201	Function	Heparin binding	IDA	18669637
GO:0008201	Function	Heparin binding	IEA
GO:0017134	Function	Fibroblast growth factor binding	IPI	18669637
GO:0019838	Function	Growth factor binding	IBA
GO:0019838	Function	Growth factor binding	IEA
GO:0031012	Component	Extracellular matrix	HDA	23658023
GO:0043117	Process	Positive regulation of vascular permeability	IDA	18669637
GO:0045743	Process	Positive regulation of fibroblast growth factor receptor signaling pathway	IGI	18669637

MIM	HGNC	e!Ensembl
620879	23428	ENSG00000174721

Q8TAT2

Protein name

Fibroblast growth factor-binding protein 3 (FGF-BP3) (FGF-binding protein 3) (FGFBP-3)

Protein function

Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which lead

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06473	FGF-BP1	13 → 258	FGF binding protein 1 (FGF-BP1)	Family

Sequence

MTPPKLRASLSPSLLLLLSGCLLAAARREKGAASNVAEPVPGPTGGSSGRFLSPEQHACS
WQLLLPAPEAAAGSELALRCQSPDGARHQCAYRGHPERCAAYAARRAHFWKQVLGGLRKK
RRPCHDPAPLQARLCAGKKGHGAELRLVPRASPPARPTVAGFAGESKPRARNRGRTRERA
SGPAAGTPPPQSAPPKENPSERKTNEGKRKAALVPNEERPMGTGPDPDGLDGNAELTETY
CAEKWHSLCNFFVNFWNG

Sequence length

258

Interactions

View interactions

	Reactome
			FGFR2b ligand binding and activation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DIABETIC KETOACIDOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 1 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anxiety	Anxiety Disorder	BEFREE	20851768		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	20851768		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	Pubtator	22016809	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	34061869	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	30374109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	30374109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	30374109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	30374109		★★★★★ ★☆☆☆☆ Found in Text Mining only

FGFBP3 (fibroblast growth factor binding protein 3)