Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	140453
Gene name	Mucin 17, cell surface associated
Gene symbol	MUC17
Synonyms (NCBI Gene)	MUC-17MUC-3MUC3
Chromosome	7
Chromosome location	7q22.1
Summary	The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize

171

Show/Hide all (171)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004710	hsa-miR-17-5p	ImmunohistochemistryMicroarrayqRT-PCR	20926598
MIRT004711	hsa-miR-20a-5p	ImmunohistochemistryMicroarrayqRT-PCR	20926598
MIRT004712	hsa-miR-20b-5p	ImmunohistochemistryMicroarrayqRT-PCR	20926598
MIRT004714	hsa-miR-30c-5p	ImmunohistochemistryMicroarrayqRT-PCR	20926598
MIRT004715	hsa-miR-30e-5p	ImmunohistochemistryMicroarrayqRT-PCR	20926598
MIRT021736	hsa-miR-132-3p	Microarray	17612493
MIRT723797	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT723796	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT723795	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT723794	hsa-miR-626	HITS-CLIP	19536157
MIRT723793	hsa-miR-6876-3p	HITS-CLIP	19536157
MIRT723792	hsa-miR-6895-3p	HITS-CLIP	19536157
MIRT723791	hsa-miR-593-3p	HITS-CLIP	19536157
MIRT723790	hsa-miR-6881-3p	HITS-CLIP	19536157
MIRT723789	hsa-miR-4279	HITS-CLIP	19536157
MIRT723788	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT723787	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	24398324
MIRT459472	hsa-miR-221-5p	PAR-CLIP	24398324
MIRT459470	hsa-miR-8073	PAR-CLIP	24398324
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	24398324
MIRT459469	hsa-miR-8053	PAR-CLIP	24398324
MIRT459468	hsa-miR-342-5p	PAR-CLIP	24398324
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	24398324
MIRT459466	hsa-miR-4651	PAR-CLIP	24398324
MIRT459465	hsa-miR-608	PAR-CLIP	24398324
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	24398324
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	24398324
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	24398324
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	24398324
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	23592263
MIRT459472	hsa-miR-221-5p	PAR-CLIP	23592263
MIRT459470	hsa-miR-8073	PAR-CLIP	23592263
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	23592263
MIRT459469	hsa-miR-8053	PAR-CLIP	23592263
MIRT459468	hsa-miR-342-5p	PAR-CLIP	23592263
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	23592263
MIRT459466	hsa-miR-4651	PAR-CLIP	23592263
MIRT459465	hsa-miR-608	PAR-CLIP	23592263
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	23592263
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	23592263
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	23592263
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	23592263
MIRT459472	hsa-miR-221-5p	PAR-CLIP	27292025
MIRT459472	hsa-miR-221-5p	PAR-CLIP	27292025
MIRT459468	hsa-miR-342-5p	PAR-CLIP	27292025
MIRT459468	hsa-miR-342-5p	PAR-CLIP	27292025
MIRT459466	hsa-miR-4651	PAR-CLIP	27292025
MIRT459466	hsa-miR-4651	PAR-CLIP	27292025
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	27292025
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	27292025
MIRT459465	hsa-miR-608	PAR-CLIP	27292025
MIRT459465	hsa-miR-608	PAR-CLIP	27292025
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	27292025
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	27292025
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	27292025
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	27292025
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	27292025
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	27292025
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	27292025
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	27292025
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	27292025
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	27292025
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	27292025
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	27292025
MIRT459469	hsa-miR-8053	PAR-CLIP	27292025
MIRT459469	hsa-miR-8053	PAR-CLIP	27292025
MIRT459470	hsa-miR-8073	PAR-CLIP	27292025
MIRT459470	hsa-miR-8073	PAR-CLIP	27292025
MIRT723797	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT723796	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT723795	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT723794	hsa-miR-626	HITS-CLIP	19536157
MIRT723793	hsa-miR-6876-3p	HITS-CLIP	19536157
MIRT723792	hsa-miR-6895-3p	HITS-CLIP	19536157
MIRT723791	hsa-miR-593-3p	HITS-CLIP	19536157
MIRT723790	hsa-miR-6881-3p	HITS-CLIP	19536157
MIRT723789	hsa-miR-4279	HITS-CLIP	19536157
MIRT723788	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT723787	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	24398324
MIRT459472	hsa-miR-221-5p	PAR-CLIP	24398324
MIRT459470	hsa-miR-8073	PAR-CLIP	24398324
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	24398324
MIRT459469	hsa-miR-8053	PAR-CLIP	24398324
MIRT459468	hsa-miR-342-5p	PAR-CLIP	24398324
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	24398324
MIRT459466	hsa-miR-4651	PAR-CLIP	24398324
MIRT459465	hsa-miR-608	PAR-CLIP	24398324
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	24398324
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	24398324
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	24398324
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	24398324
MIRT459473	hsa-miR-6890-5p	PAR-CLIP	23592263
MIRT459472	hsa-miR-221-5p	PAR-CLIP	23592263
MIRT459470	hsa-miR-8073	PAR-CLIP	23592263
MIRT459471	hsa-miR-6717-5p	PAR-CLIP	23592263
MIRT459469	hsa-miR-8053	PAR-CLIP	23592263
MIRT459468	hsa-miR-342-5p	PAR-CLIP	23592263
MIRT459467	hsa-miR-4664-5p	PAR-CLIP	23592263
MIRT459466	hsa-miR-4651	PAR-CLIP	23592263
MIRT459465	hsa-miR-608	PAR-CLIP	23592263
MIRT459464	hsa-miR-6747-5p	PAR-CLIP	23592263
MIRT459463	hsa-miR-6737-5p	PAR-CLIP	23592263
MIRT459462	hsa-miR-6812-5p	PAR-CLIP	23592263
MIRT459461	hsa-miR-6819-5p	PAR-CLIP	23592263
MIRT1166108	hsa-miR-106a	CLIP-seq
MIRT1166109	hsa-miR-106b	CLIP-seq
MIRT1166110	hsa-miR-1321	CLIP-seq
MIRT1166111	hsa-miR-17	CLIP-seq
MIRT1166112	hsa-miR-190	CLIP-seq
MIRT1166113	hsa-miR-190b	CLIP-seq
MIRT1166114	hsa-miR-20a	CLIP-seq
MIRT1166115	hsa-miR-20b	CLIP-seq
MIRT1166116	hsa-miR-302a	CLIP-seq
MIRT1166117	hsa-miR-302b	CLIP-seq
MIRT1166118	hsa-miR-302c	CLIP-seq
MIRT1166119	hsa-miR-302d	CLIP-seq
MIRT1166120	hsa-miR-302e	CLIP-seq
MIRT1166121	hsa-miR-3126-5p	CLIP-seq
MIRT1166122	hsa-miR-3609	CLIP-seq
MIRT1166123	hsa-miR-361-5p	CLIP-seq
MIRT1166124	hsa-miR-3689a-5p	CLIP-seq
MIRT1166125	hsa-miR-3689b	CLIP-seq
MIRT1166126	hsa-miR-3689e	CLIP-seq
MIRT1166127	hsa-miR-3689f	CLIP-seq
MIRT1166128	hsa-miR-372	CLIP-seq
MIRT1166129	hsa-miR-373	CLIP-seq
MIRT1166130	hsa-miR-380	CLIP-seq
MIRT1166131	hsa-miR-3919	CLIP-seq
MIRT1166132	hsa-miR-4419a	CLIP-seq
MIRT1166133	hsa-miR-4495	CLIP-seq
MIRT1166134	hsa-miR-4510	CLIP-seq
MIRT1166135	hsa-miR-4684-3p	CLIP-seq
MIRT1166136	hsa-miR-4690-5p	CLIP-seq
MIRT1166137	hsa-miR-4739	CLIP-seq
MIRT1166138	hsa-miR-4756-3p	CLIP-seq
MIRT1166139	hsa-miR-4756-5p	CLIP-seq
MIRT1166140	hsa-miR-4796-3p	CLIP-seq
MIRT1166141	hsa-miR-519a	CLIP-seq
MIRT1166142	hsa-miR-519b-3p	CLIP-seq
MIRT1166143	hsa-miR-519c-3p	CLIP-seq
MIRT1166144	hsa-miR-519d	CLIP-seq
MIRT1166145	hsa-miR-520a-3p	CLIP-seq
MIRT1166146	hsa-miR-520b	CLIP-seq
MIRT1166147	hsa-miR-520c-3p	CLIP-seq
MIRT1166148	hsa-miR-520d-3p	CLIP-seq
MIRT1166149	hsa-miR-520e	CLIP-seq
MIRT1166150	hsa-miR-548ah	CLIP-seq
MIRT1166151	hsa-miR-621	CLIP-seq
MIRT1166152	hsa-miR-758	CLIP-seq
MIRT1166153	hsa-miR-767-3p	CLIP-seq
MIRT1166154	hsa-miR-93	CLIP-seq
MIRT1166135	hsa-miR-4684-3p	CLIP-seq
MIRT1166110	hsa-miR-1321	CLIP-seq
MIRT1166121	hsa-miR-3126-5p	CLIP-seq
MIRT1166123	hsa-miR-361-5p	CLIP-seq
MIRT2048011	hsa-miR-3675-5p	CLIP-seq
MIRT1166131	hsa-miR-3919	CLIP-seq
MIRT1166132	hsa-miR-4419a	CLIP-seq
MIRT1166134	hsa-miR-4510	CLIP-seq
MIRT1166135	hsa-miR-4684-3p	CLIP-seq
MIRT1166137	hsa-miR-4739	CLIP-seq
MIRT1166138	hsa-miR-4756-3p	CLIP-seq
MIRT1166139	hsa-miR-4756-5p	CLIP-seq
MIRT2276777	hsa-miR-3202	CLIP-seq
MIRT1166123	hsa-miR-361-5p	CLIP-seq
MIRT1166131	hsa-miR-3919	CLIP-seq
MIRT2276778	hsa-miR-4533	CLIP-seq
MIRT1166138	hsa-miR-4756-3p	CLIP-seq
MIRT1166135	hsa-miR-4684-3p	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
CDX2	Unknown	16737958
NFKB1	Unknown	16737958
RELA	Unknown	16737958

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17990980
GO:0005576	Component	Extracellular region	IEA
GO:0005796	Component	Golgi lumen	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0009897	Component	External side of plasma membrane	IDA	12888891
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IDA	17990980
GO:0019725	Process	Cellular homeostasis	TAS	17990980
GO:0030165	Function	PDZ domain binding	IPI	17990980
GO:0030197	Function	Extracellular matrix constituent, lubricant activity	HDA	28344315
GO:0031012	Component	Extracellular matrix	HDA	28344315
GO:0071944	Component	Cell periphery	IEA

MIM	HGNC	e!Ensembl
608424	16800	ENSG00000169876

Q685J3

Protein name

Mucin-17 (MUC-17) (Small intestinal mucin-3) (MUC-3)

Protein function

Probably plays a role in maintaining homeostasis on mucosal surfaces.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01390	SEA	4186 → 4287	SEA domain	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. High

Sequence

MPRPGTMALCLLTLVLSLLPPQAAAEQDLSVNRAVWDGGGCISQGDVLNRQCQQLSQHVR
TGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSE
STSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTY
KVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTP
VEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPA
ATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVD
TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS
KTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK
TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTST
PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTF
VTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPV
TTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVT
TSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT
STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS
TEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST
EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE
ATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEA
SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQAS
SSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASS
SPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSP
PPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSP
TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPT
PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT
SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA
EGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE
GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADG
TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS
MTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSM
PTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP
NSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPT
STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATS
TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST
PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAY
SEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPS
ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEG
SPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRR
TPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGST
PFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP
LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL
TRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLT
SVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS
MPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI
PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMP
VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILV
STMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVS
TTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVST
LPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT
PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP
VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV
AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVA
SSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAI
PEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSS
AISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSE
DSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEAS
ILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETST
LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL
STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLS
TTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLST
TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT
PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS
VDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPV
DTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVV
TSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVY
TSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG
DTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPL
DTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGA
VSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRG
CTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSAS
STTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGC
QNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTVTVTSVKFT
EELKNHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLRLGSVVVEHDVLLRTKYTPE
YKTVLDNATEVVKEKITKVTTQQIMINDICSDMMCFNTTGTQVQNITVTQYDPEEDCRKM
AKEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQMSLSGPQCLCVTTETHWYSGE
TCNQGTQKSLVYGLVGAGVVLMLIILVALLMLVFRSKREVKRQKYRLSQLYKWQEEDSGP
APGTFQNIGFDICQDDDSIHLESIYSNFQPSLRHIDPETKIRIQRPQVMTTSF

Sequence length

4493

Interactions

View interactions

	Reactome
			Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC KIDNEY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GESTATIONAL DIABETES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Papillary renal cell carcinoma type 1	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (62)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	12657964, 7678777, 8859775		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of pancreas	Pancreatic adenocarcinoma	BEFREE	12657964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma, Clear Cell	Adenocarcinoma	BEFREE	12010365		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenoma	Adenoma	BEFREE	11241413, 24533081		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenomatous Polyps	Adenomatous Polyposis	BEFREE	8859775		★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	19817750		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anophthalmia with pulmonary hypoplasia	Anophthalmia	Pubtator	20926598	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	BEFREE	18163520		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	Pubtator	18163520	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	18163520	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	BEFREE	11076872		★★★★★ ★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	Pubtator	11076872	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	8443822		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	15255542, 15976813, 31879365, 34888385	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bronchioloalveolar Adenocarcinoma	Lung adenocarcinoma	BEFREE	11274635		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	12010365, 29575536		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	8638091		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	19817750, 20926598, 22970168	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	30226566		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	20211273		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	Pubtator	20702471	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	20702471	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	32322884	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	11855812, 7678777, 8020672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	17349047		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	17349047, 29575536	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	20702471	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	12010365, 14550470		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	11559653		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	11559653	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Breast Carcinoma	Breast Carcinoma	BEFREE	12657964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	26285705		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	Pubtator	26285705	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	22970168	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Infertility	Infertility	Pubtator	26285705	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	8813081		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	8638091		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	8638091	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	19817750	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	8443822		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	8638091		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	9850092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	22970168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	30778796, 31262330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	15243562, 15375564, 17349047, 20926598, 31262330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	11855812, 7678777, 8020672, 8813081		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	30226566		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	30226566	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12010365, 12171961, 12657964, 14550470, 17349047, 29778426, 8020672, 8694545, 8813081, 9850092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Noninfiltrating Intraductal Carcinoma	Ductal carcinoma	BEFREE	11348414		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	26285705	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	22970168		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	12657964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	22970168	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	28198987	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	12010365		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	18163520		★★★★★ ★☆☆☆☆ Found in Text Mining only
Salivary Gland Neoplasms	Salivary gland neoplasm	BEFREE	21723776		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	30778796, 31262330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	12719460, 26330360	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	30778796	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	11289722, 9931338		★★★★★ ★☆☆☆☆ Found in Text Mining only

MUC17 (mucin 17, cell surface associated)