C9orf57 (chromosome 9 open reading frame 57)

Gene

• Entrez ID: 138240
• Gene name: Chromosome 9 open reading frame 57
• Gene symbol: C9orf57
• Synonyms (NCBI Gene): -
• Chromosome: 9
• Chromosome location: 9q21.13

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT855354	hsa-miR-185	CLIP-seq
MIRT855355	hsa-miR-298	CLIP-seq
MIRT855356	hsa-miR-3150b-3p	CLIP-seq
MIRT855357	hsa-miR-3173-3p	CLIP-seq
MIRT855358	hsa-miR-330-3p	CLIP-seq
MIRT855359	hsa-miR-3919	CLIP-seq
MIRT855360	hsa-miR-4306	CLIP-seq
MIRT855361	hsa-miR-4328	CLIP-seq
MIRT855362	hsa-miR-4422	CLIP-seq
MIRT855363	hsa-miR-4644	CLIP-seq
MIRT855364	hsa-miR-4784	CLIP-seq
MIRT855365	hsa-miR-4797-5p	CLIP-seq
MIRT855366	hsa-miR-522	CLIP-seq
MIRT855367	hsa-miR-539	CLIP-seq
MIRT855368	hsa-miR-765	CLIP-seq
MIRT1954110	hsa-miR-1237	CLIP-seq
MIRT1954111	hsa-miR-1248	CLIP-seq
MIRT1954112	hsa-miR-223	CLIP-seq
MIRT1954113	hsa-miR-224	CLIP-seq
MIRT1954114	hsa-miR-3143	CLIP-seq
MIRT1954115	hsa-miR-3674	CLIP-seq
MIRT855361	hsa-miR-4328	CLIP-seq
MIRT1954116	hsa-miR-4659a-3p	CLIP-seq
MIRT1954117	hsa-miR-4659b-3p	CLIP-seq
MIRT1954118	hsa-miR-543	CLIP-seq
MIRT1954110	hsa-miR-1237	CLIP-seq
MIRT1954111	hsa-miR-1248	CLIP-seq
MIRT1954114	hsa-miR-3143	CLIP-seq
MIRT2191597	hsa-miR-3614-3p	CLIP-seq
MIRT1954115	hsa-miR-3674	CLIP-seq
MIRT2191598	hsa-miR-3973	CLIP-seq
MIRT2191599	hsa-miR-4312	CLIP-seq
MIRT2191600	hsa-miR-4536	CLIP-seq
MIRT1954118	hsa-miR-543	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5W0N0
• Protein name: Uncharacterized protein C9orf57
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15851	DUF4723	37 → 74	Domain of unknown function (DUF4723)	Family
  PF15851	DUF4723	75 → 160	Domain of unknown function (DUF4723)	Family

• Sequence:

  MKKIEISGTCLSFHLLFGLEIRMRRIVFAGVILFRLLGVILFRLLGVILFGRLGDLGTCQ
  TKPGQYWKEEVHIQDVGGLICRACNLSLPFHGCLLDLGTCQAEPGQYCKEEVHIQGGIQW
  YSVKGCTKNTSECFKSTLVKRILQLHELVTTHCCNHSLCNF

• Sequence length: 161

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations