Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	136647
Gene name	M-phase specific PLK1 interacting protein
Gene symbol	MPLKIP
Synonyms (NCBI Gene)	ABHSC7orf11ORF20TTD4
Chromosome	7
Chromosome location	7p14.1
Summary	The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is

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miRTarBase ID	miRNA	Experiments	Reference
MIRT043354	hsa-miR-331-3p	CLASH	23622248
MIRT723768	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT723767	hsa-miR-4282	HITS-CLIP	19536157
MIRT723766	hsa-miR-3607-3p	HITS-CLIP	19536157
MIRT723765	hsa-miR-8055	HITS-CLIP	19536157
MIRT723764	hsa-miR-129-5p	HITS-CLIP	19536157
MIRT701882	hsa-miR-3174	HITS-CLIP	23313552
MIRT701881	hsa-miR-4257	HITS-CLIP	23313552
MIRT701880	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT701879	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT701877	hsa-miR-558	HITS-CLIP	23313552
MIRT701878	hsa-miR-4487	HITS-CLIP	23313552
MIRT459369	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT459368	hsa-miR-6086	HITS-CLIP	23313552
MIRT459399	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT701876	hsa-miR-4252	HITS-CLIP	23313552
MIRT459397	hsa-miR-3612	HITS-CLIP	23313552
MIRT459396	hsa-miR-650	HITS-CLIP	23313552
MIRT701875	hsa-miR-6073	HITS-CLIP	23313552
MIRT701874	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT701873	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT701872	hsa-miR-921	HITS-CLIP	23313552
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT667364	hsa-miR-6750-3p	HITS-CLIP	23824327
MIRT667363	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT667362	hsa-miR-5693	HITS-CLIP	23824327
MIRT459366	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT667361	hsa-miR-3135b	HITS-CLIP	23824327
MIRT667360	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT667359	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT667358	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT667357	hsa-miR-566	HITS-CLIP	23824327
MIRT667356	hsa-miR-3652	HITS-CLIP	23824327
MIRT667355	hsa-miR-4430	HITS-CLIP	23824327
MIRT667354	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT667353	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT667352	hsa-miR-5698	HITS-CLIP	23824327
MIRT648156	hsa-miR-34c-3p	HITS-CLIP	23824327
MIRT648155	hsa-miR-2115-3p	HITS-CLIP	23824327
MIRT648154	hsa-miR-4729	HITS-CLIP	23824327
MIRT648153	hsa-miR-374a-3p	HITS-CLIP	23824327
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT632730	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT632729	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT632728	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT648152	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT632727	hsa-miR-1976	HITS-CLIP	23824327
MIRT632726	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT632725	hsa-miR-4279	HITS-CLIP	23824327
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT632730	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT632729	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT632728	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT632727	hsa-miR-1976	HITS-CLIP	23824327
MIRT632726	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT632725	hsa-miR-4279	HITS-CLIP	23824327
MIRT459377	hsa-miR-302f	PAR-CLIP	21572407
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	21572407
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT459371	hsa-miR-1827	PAR-CLIP	21572407
MIRT459370	hsa-miR-6134	PAR-CLIP	21572407
MIRT459369	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT459368	hsa-miR-6086	PAR-CLIP	21572407
MIRT459367	hsa-miR-298	PAR-CLIP	21572407
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT459365	hsa-miR-3689d	PAR-CLIP	21572407
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	21572407
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	21572407
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	21572407
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	21572407
MIRT459360	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT459358	hsa-miR-1273e	PAR-CLIP	21572407
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT530617	hsa-miR-562	PAR-CLIP	22012620
MIRT530615	hsa-miR-4438	PAR-CLIP	22012620
MIRT530616	hsa-miR-5582-5p	PAR-CLIP	22012620
MIRT530614	hsa-miR-4269	PAR-CLIP	22012620
MIRT530613	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT530612	hsa-miR-619-5p	PAR-CLIP	22012620
MIRT530611	hsa-miR-6506-5p	PAR-CLIP	22012620
MIRT530610	hsa-miR-5589-3p	PAR-CLIP	22012620
MIRT530609	hsa-miR-5095	PAR-CLIP	22012620
MIRT530608	hsa-miR-7151-3p	PAR-CLIP	22012620
MIRT459377	hsa-miR-302f	PAR-CLIP	23446348
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	23446348
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	23446348
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	23446348
MIRT459373	hsa-miR-4649-3p	PAR-CLIP	23446348
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT459371	hsa-miR-1827	PAR-CLIP	23446348
MIRT459370	hsa-miR-6134	PAR-CLIP	23446348
MIRT459369	hsa-miR-377-5p	PAR-CLIP	23446348
MIRT459368	hsa-miR-6086	PAR-CLIP	23446348
MIRT459367	hsa-miR-298	PAR-CLIP	23446348
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT518042	hsa-miR-7160-5p	PAR-CLIP	23446348
MIRT459365	hsa-miR-3689d	PAR-CLIP	23446348
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	23446348
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT459360	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT459358	hsa-miR-1273e	PAR-CLIP	23446348
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT518041	hsa-miR-665	PAR-CLIP	23446348
MIRT489891	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT489890	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT489889	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT489888	hsa-miR-4519	PAR-CLIP	23592263
MIRT489887	hsa-miR-4781-5p	PAR-CLIP	23592263
MIRT489886	hsa-miR-6513-3p	PAR-CLIP	23592263
MIRT489885	hsa-miR-4494	PAR-CLIP	23592263
MIRT489884	hsa-miR-499b-5p	PAR-CLIP	23592263
MIRT489883	hsa-miR-1253	PAR-CLIP	23592263
MIRT489882	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT489881	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT489880	hsa-miR-107	PAR-CLIP	23592263
MIRT489879	hsa-miR-7-5p	PAR-CLIP	23592263
MIRT489878	hsa-miR-4271	PAR-CLIP	23592263
MIRT489877	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT489876	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT489875	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT489874	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT489873	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT489872	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT489871	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT459403	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT459402	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT459401	hsa-miR-940	PAR-CLIP	23592263
MIRT459400	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT459399	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT459398	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT459397	hsa-miR-3612	PAR-CLIP	23592263
MIRT459396	hsa-miR-650	PAR-CLIP	23592263
MIRT459395	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT459394	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT459393	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT459392	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT459391	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT459390	hsa-miR-7158-3p	PAR-CLIP	23592263
MIRT459389	hsa-miR-203b-3p	PAR-CLIP	23592263
MIRT459388	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT459387	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT459386	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT459385	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT459384	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT459383	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT459382	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT459381	hsa-miR-3689c	PAR-CLIP	23592263
MIRT459380	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT459379	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT459378	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT459377	hsa-miR-302f	PAR-CLIP	23592263
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT459373	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT459371	hsa-miR-1827	PAR-CLIP	23592263
MIRT459370	hsa-miR-6134	PAR-CLIP	23592263
MIRT459369	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT459368	hsa-miR-6086	PAR-CLIP	23592263
MIRT459367	hsa-miR-298	PAR-CLIP	23592263
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT459365	hsa-miR-3689d	PAR-CLIP	23592263
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT459360	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT459358	hsa-miR-1273e	PAR-CLIP	23592263
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT667353	hsa-miR-4764-3p	PAR-CLIP	26701625
MIRT667353	hsa-miR-4764-3p	PAR-CLIP	27292025
MIRT667353	hsa-miR-4764-3p	PAR-CLIP	27292025
MIRT723768	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT723767	hsa-miR-4282	HITS-CLIP	19536157
MIRT723766	hsa-miR-3607-3p	HITS-CLIP	19536157
MIRT723765	hsa-miR-8055	HITS-CLIP	19536157
MIRT723764	hsa-miR-129-5p	HITS-CLIP	19536157
MIRT701882	hsa-miR-3174	HITS-CLIP	23313552
MIRT701881	hsa-miR-4257	HITS-CLIP	23313552
MIRT701880	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT701879	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT701877	hsa-miR-558	HITS-CLIP	23313552
MIRT701878	hsa-miR-4487	HITS-CLIP	23313552
MIRT459369	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT459368	hsa-miR-6086	HITS-CLIP	23313552
MIRT459399	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT701876	hsa-miR-4252	HITS-CLIP	23313552
MIRT459397	hsa-miR-3612	HITS-CLIP	23313552
MIRT459396	hsa-miR-650	HITS-CLIP	23313552
MIRT701875	hsa-miR-6073	HITS-CLIP	23313552
MIRT701874	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT701873	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT701872	hsa-miR-921	HITS-CLIP	23313552
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT667364	hsa-miR-6750-3p	HITS-CLIP	23824327
MIRT667363	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT667362	hsa-miR-5693	HITS-CLIP	23824327
MIRT459366	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT667361	hsa-miR-3135b	HITS-CLIP	23824327
MIRT667360	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT667359	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT667358	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT667357	hsa-miR-566	HITS-CLIP	23824327
MIRT667356	hsa-miR-3652	HITS-CLIP	23824327
MIRT667355	hsa-miR-4430	HITS-CLIP	23824327
MIRT667354	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT667353	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT667352	hsa-miR-5698	HITS-CLIP	23824327
MIRT648156	hsa-miR-34c-3p	HITS-CLIP	23824327
MIRT648155	hsa-miR-2115-3p	HITS-CLIP	23824327
MIRT648154	hsa-miR-4729	HITS-CLIP	23824327
MIRT648153	hsa-miR-374a-3p	HITS-CLIP	23824327
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT632730	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT632729	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT632728	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT648152	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT632727	hsa-miR-1976	HITS-CLIP	23824327
MIRT632726	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT632725	hsa-miR-4279	HITS-CLIP	23824327
MIRT632731	hsa-miR-4661-5p	HITS-CLIP	23824327
MIRT632730	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT632729	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT632728	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT632727	hsa-miR-1976	HITS-CLIP	23824327
MIRT632726	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT632725	hsa-miR-4279	HITS-CLIP	23824327
MIRT459377	hsa-miR-302f	PAR-CLIP	21572407
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	21572407
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT459371	hsa-miR-1827	PAR-CLIP	21572407
MIRT459370	hsa-miR-6134	PAR-CLIP	21572407
MIRT459369	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT459368	hsa-miR-6086	PAR-CLIP	21572407
MIRT459367	hsa-miR-298	PAR-CLIP	21572407
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT459365	hsa-miR-3689d	PAR-CLIP	21572407
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	21572407
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	21572407
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	21572407
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	21572407
MIRT459360	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT459358	hsa-miR-1273e	PAR-CLIP	21572407
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT530617	hsa-miR-562	PAR-CLIP	22012620
MIRT530615	hsa-miR-4438	PAR-CLIP	22012620
MIRT530616	hsa-miR-5582-5p	PAR-CLIP	22012620
MIRT530614	hsa-miR-4269	PAR-CLIP	22012620
MIRT530613	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT530612	hsa-miR-619-5p	PAR-CLIP	22012620
MIRT530611	hsa-miR-6506-5p	PAR-CLIP	22012620
MIRT530610	hsa-miR-5589-3p	PAR-CLIP	22012620
MIRT530609	hsa-miR-5095	PAR-CLIP	22012620
MIRT530608	hsa-miR-7151-3p	PAR-CLIP	22012620
MIRT459377	hsa-miR-302f	PAR-CLIP	23446348
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	23446348
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	23446348
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	23446348
MIRT459373	hsa-miR-4649-3p	PAR-CLIP	23446348
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT459371	hsa-miR-1827	PAR-CLIP	23446348
MIRT459370	hsa-miR-6134	PAR-CLIP	23446348
MIRT459369	hsa-miR-377-5p	PAR-CLIP	23446348
MIRT459368	hsa-miR-6086	PAR-CLIP	23446348
MIRT459367	hsa-miR-298	PAR-CLIP	23446348
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT518042	hsa-miR-7160-5p	PAR-CLIP	23446348
MIRT459365	hsa-miR-3689d	PAR-CLIP	23446348
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	23446348
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT459360	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT459358	hsa-miR-1273e	PAR-CLIP	23446348
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT518041	hsa-miR-665	PAR-CLIP	23446348
MIRT489891	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT489890	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT489889	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT489888	hsa-miR-4519	PAR-CLIP	23592263
MIRT489887	hsa-miR-4781-5p	PAR-CLIP	23592263
MIRT489886	hsa-miR-6513-3p	PAR-CLIP	23592263
MIRT489885	hsa-miR-4494	PAR-CLIP	23592263
MIRT489884	hsa-miR-499b-5p	PAR-CLIP	23592263
MIRT489883	hsa-miR-1253	PAR-CLIP	23592263
MIRT489882	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT489881	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT489880	hsa-miR-107	PAR-CLIP	23592263
MIRT489879	hsa-miR-7-5p	PAR-CLIP	23592263
MIRT489878	hsa-miR-4271	PAR-CLIP	23592263
MIRT489877	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT489876	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT489875	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT489874	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT489873	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT489872	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT489871	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT459403	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT459402	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT459401	hsa-miR-940	PAR-CLIP	23592263
MIRT459400	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT459399	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT459398	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT459397	hsa-miR-3612	PAR-CLIP	23592263
MIRT459396	hsa-miR-650	PAR-CLIP	23592263
MIRT459395	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT459394	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT459393	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT459392	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT459391	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT459390	hsa-miR-7158-3p	PAR-CLIP	23592263
MIRT459389	hsa-miR-203b-3p	PAR-CLIP	23592263
MIRT459388	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT459387	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT459386	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT459385	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT459384	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT459383	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT459382	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT459381	hsa-miR-3689c	PAR-CLIP	23592263
MIRT459380	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT459379	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT459378	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT459377	hsa-miR-302f	PAR-CLIP	23592263
MIRT459376	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT459375	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT459374	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT459373	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT459372	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT459371	hsa-miR-1827	PAR-CLIP	23592263
MIRT459370	hsa-miR-6134	PAR-CLIP	23592263
MIRT459369	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT459368	hsa-miR-6086	PAR-CLIP	23592263
MIRT459367	hsa-miR-298	PAR-CLIP	23592263
MIRT459366	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT459365	hsa-miR-3689d	PAR-CLIP	23592263
MIRT459364	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT459363	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT459362	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT459361	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT459360	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT459358	hsa-miR-1273e	PAR-CLIP	23592263
MIRT459359	hsa-miR-6516-5p	PAR-CLIP	23592263

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17310276, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	17310276
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	17310276
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA	17310276
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0030496	Component	Midbody	IBA
GO:0030496	Component	Midbody	IDA	17310276
GO:0051301	Process	Cell division	IEA

MIM	HGNC	e!Ensembl
609188	16002	ENSG00000168303

Q8TAP9

Protein name

M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein)

Protein function

May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15502	MPLKIP	94 → 179	M-phase-specific PLK1-interacting protein	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed at highest levels in liver and kidney; intermediate expression in skeletal muscle, pancreas, heart and placenta; low expression in brain and lung. Expressed in epidermis and hair follicles. {ECO:0000269|PubMed:11829489, ECO:0

Sequence

MQRQNFRPPTPPYPGPGGGGWGSGSSFRGTPGGGGPRPPSPRDGYGSPHHTPPYGPRSRP
YGSSHSPRHGGSFPGGRFGSPSPGGYPGSYSRSPAGSQQQFGYSPGQQQTHPQGSPRTST
PFGSGRVREKRMSNELENYFKPSMLEDPWAGLEPVSVVDISQQYSNTQTFTGKKGRYFC

Sequence length

179

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Trichothiodystrophy 1, photosensitive	Pathogenic	rs768342562	RCV000202381	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Trichothiodystrophy 4, nonphotosensitive	Pathogenic; Likely pathogenic	rs2150561563, rs137853117, rs587776531, rs587776532, rs878854339, rs869312900, rs2484133876	RCV001806299 RCV000001918 RCV000001919 RCV000001921 RCV000001922 RCV000210474 RCV004577217 View all (2 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
MPLKIP-related disorder	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRICHORRHEXIS NODOSA SYNDROME	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRICHOTHIODYSTROPHY	—	GenCC, Orphanet GenCC, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRICHOTHIODYSTROPHY SYNDROMES	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (61)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Age related macular degeneration	Age-related macular degeneration	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Amish Brittle Hair Brain Syndrome	Amish Brittle Hair Brain Syndrome	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Astigmatism	Astigmatism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Bilateral microphthalmos	Microphthalmos	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Bronchospasm	Bronchospasm	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	26880286		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	Pubtator	26880286	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral cortical atrophy	Cerebral cortical atrophy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Clastothrix	Clastothrix	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Epicanthus	Congenital Epicanthus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital exfoliative erythroderma	Congenital exfoliative erythroderma	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital exomphalos	Congenital Exomphalos	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Craniosynostosis	Craniosynostosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Dental Enamel Hypoplasia	Dental Enamel Hypoplasia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysarthria	Dysarthria	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectropion	Ectropion	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	25290684		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esotropia	Esotropia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Generalized seizures	Seizure	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Gonadal Dysgenesis	Gonadal Dysgenesis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypogonadism	Hypogonadism	Pubtator	30598092	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoplasia of mandible relative to maxilla	Hypoplasia of mandible relative to maxilla	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ichthyoses	Ichthyosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired social reciprocity	Impaired social reciprocity	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	15645389	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Kaposi Sarcoma	Kaposi Sarcoma	BEFREE	29499066		★★★★★ ★☆☆☆☆ Found in Text Mining only
Keratoconjunctivitis Sicca	Keratoconjunctivitis Sicca	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukomalacia, Periventricular	Periventricular Leukomalacia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Macrotia	Macrotia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcornea	Microcornea	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Neutropenia	Neutropenia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteopenia	Osteopenia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosclerosis	Osteosclerosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Paraplegia/paraparesis	Paraplegia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Partial agenesis of corpus callosum	Partial Agenesis Of Corpus Callosum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Primary hypogonadism	Hypogonadism	BEFREE	30598092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorineural hearing loss, bilateral	Sensorineural hearing loss	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Tricho-thiodystrophy disorder	Trichothiodystrophy	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Trichorrhexis nodosa syndrome	Trichorrhexis Nodosa Syndrome	UNIPROT_DG	15645389		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichorrhexis nodosa syndrome	Trichorrhexis Nodosa Syndrome	GENOMICS_ENGLAND_DG	21959366		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy	Trichothiodystrophy	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy Syndromes	Trichothiodystrophy	BEFREE	15645389, 16977596, 25290684, 26518168, 26880286		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy Syndromes	Trichothiodystrophy	Pubtator	15645389, 26880286, 30580289, 30598092, 37800682	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy Syndromes	Trichothiodystrophy	ORPHANET_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy Syndromes	Trichothiodystrophy	CTD_human_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Trichothiodystrophy, Nonphotosensitive 1	Trichothiodystrophy	CLINVAR_DG	26880286		★★★★★ ★☆☆☆☆ Found in Text Mining only
Trichothiodystrophy, Nonphotosensitive 1	Trichothiodystrophy	BEFREE	30598092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Trichothiodystrophy, Nonphotosensitive 1	Trichothiodystrophy	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ventricular Septal Defects	Ventricular septal defect	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only

MPLKIP (M-phase specific PLK1 interacting protein)