GPR151 (G protein-coupled receptor 151)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 134391
Gene name G protein-coupled receptor 151
Gene symbol GPR151
Synonyms (NCBI Gene)
GALR4GALRLGPCRGPCR-2037PGR7
Chromosome 5
Chromosome location 5q32
Summary This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin recept
miRNA miRNA information provided by mirtarbase database.
20
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (20)
miRTarBase ID miRNA Experiments Reference
MIRT620389 hsa-miR-548e-5p HITS-CLIP 23824327
MIRT648006 hsa-miR-4803 HITS-CLIP 23824327
MIRT620388 hsa-miR-548p HITS-CLIP 23824327
MIRT620387 hsa-miR-8063 HITS-CLIP 23824327
MIRT620386 hsa-miR-1468-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (19)
GO ID Ontology Definition Evidence Reference
GO:0002931 Process Response to ischemia ISS
GO:0004930 Function G protein-coupled receptor activity IBA
GO:0004930 Function G protein-coupled receptor activity IEA
GO:0004930 Function G protein-coupled receptor activity IMP 31119277
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
618487 23624 ENSG00000173250
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TDV0
Protein name G-protein coupled receptor 151 (G-protein coupled receptor PGR7) (GPCR-2037) (Galanin receptor 4) (Galanin-receptor-like protein) (GalRL)
Protein function Proton-sensing G-protein coupled receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 53 → 306 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: High expression in the spinal cord. {ECO:0000269|PubMed:15111018}.
Sequence
Sequence length 419
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Essential tremor Benign ClinVar
Disgenet
★★★★★
★★★☆☆
Reported in Unknown/Other Associations (≥2 sources)
Show/Hide Text Mining Associations (121)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acrodysostosis Acrodysostosis BEFREE 27908835
★★★★★
★☆☆☆☆
Found in Text Mining only
Acth-Independent Macronodular Adrenal Hyperplasia Cushing`s Syndrome BEFREE 20660048
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute Coronary Syndrome Coronary Syndrome BEFREE 12818251
★★★★★
★☆☆☆☆
Found in Text Mining only
Albinism Albinism BEFREE 18828673
★★★★★
★☆☆☆☆
Found in Text Mining only
Aortic Valve Insufficiency Aortic Valve Insufficiency BEFREE 29393391
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Arthritis BEFREE 30576947
★★★★★
★☆☆☆☆
Found in Text Mining only
Asthma Asthma BEFREE 11728229, 17154652, 21392828, 31767622
★★★★★
★☆☆☆☆
Found in Text Mining only
Autoimmune Diseases Autoimmune Diseases BEFREE 28855694, 29363585, 30409535, 30827936, 30856323
★★★★★
★☆☆☆☆
Found in Text Mining only
Bipolar Disorder Bipolar Disorder BEFREE 15452587
★★★★★
★☆☆☆☆
Found in Text Mining only
Blood Coagulation Disorders Blood Coagulation Disorders BEFREE 28212842
★★★★★
★☆☆☆☆
Found in Text Mining only