Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	133688
Gene name	UDP glycosyltransferase family 3 member A1
Gene symbol	UGT3A1
Synonyms (NCBI Gene)	-
Chromosome	5
Chromosome location	5p13.2

110

Show/Hide all (110)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025168	hsa-miR-181a-5p	Microarray	17612493
MIRT664609	hsa-miR-4802-3p	HITS-CLIP	23824327
MIRT664608	hsa-miR-4272	HITS-CLIP	23824327
MIRT664607	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT664606	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT664605	hsa-miR-6715b-3p	HITS-CLIP	23824327
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	21572407
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	21572407
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	21572407
MIRT531541	hsa-miR-498	PAR-CLIP	21572407
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	22012620
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	22012620
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	22012620
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT531541	hsa-miR-498	PAR-CLIP	22012620
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	26701625
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	26701625
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	26701625
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	26701625
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	26701625
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	26701625
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	26701625
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	26701625
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	26701625
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	26701625
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	26701625
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	26701625
MIRT531541	hsa-miR-498	PAR-CLIP	26701625
MIRT531541	hsa-miR-498	PAR-CLIP	26701625
MIRT531541	hsa-miR-498	PAR-CLIP	26701625
MIRT531541	hsa-miR-498	PAR-CLIP	26701625
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	26701625
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	27292025
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	27292025
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	27292025
MIRT531541	hsa-miR-498	PAR-CLIP	27292025
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	27292025
MIRT664609	hsa-miR-4802-3p	HITS-CLIP	23824327
MIRT664608	hsa-miR-4272	HITS-CLIP	23824327
MIRT664607	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT664606	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT664605	hsa-miR-6715b-3p	HITS-CLIP	23824327
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	21572407
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	21572407
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	21572407
MIRT531541	hsa-miR-498	PAR-CLIP	21572407
MIRT531545	hsa-miR-3156-5p	PAR-CLIP	22012620
MIRT531544	hsa-miR-219b-3p	PAR-CLIP	22012620
MIRT531543	hsa-miR-219a-2-3p	PAR-CLIP	22012620
MIRT531542	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT531541	hsa-miR-498	PAR-CLIP	22012620
MIRT1473687	hsa-miR-2276	CLIP-seq
MIRT1473688	hsa-miR-2682	CLIP-seq
MIRT1473689	hsa-miR-3115	CLIP-seq
MIRT1473690	hsa-miR-3163	CLIP-seq
MIRT1473691	hsa-miR-3170	CLIP-seq
MIRT1473692	hsa-miR-34a	CLIP-seq
MIRT1473693	hsa-miR-34c-5p	CLIP-seq
MIRT1473694	hsa-miR-3714	CLIP-seq
MIRT1473695	hsa-miR-4314	CLIP-seq
MIRT1473696	hsa-miR-4327	CLIP-seq
MIRT1473697	hsa-miR-4420	CLIP-seq
MIRT1473698	hsa-miR-4446-5p	CLIP-seq
MIRT1473699	hsa-miR-449a	CLIP-seq
MIRT1473700	hsa-miR-449b	CLIP-seq
MIRT1473701	hsa-miR-449c	CLIP-seq
MIRT1473702	hsa-miR-4646-3p	CLIP-seq
MIRT1473703	hsa-miR-4654	CLIP-seq
MIRT1473704	hsa-miR-4667-5p	CLIP-seq
MIRT1473705	hsa-miR-4700-5p	CLIP-seq
MIRT1473706	hsa-miR-4708-3p	CLIP-seq
MIRT1473707	hsa-miR-4755-5p	CLIP-seq
MIRT1473708	hsa-miR-4769-5p	CLIP-seq
MIRT1473709	hsa-miR-4777-5p	CLIP-seq
MIRT1473710	hsa-miR-515-5p	CLIP-seq
MIRT1473711	hsa-miR-629	CLIP-seq
MIRT1473712	hsa-miR-637	CLIP-seq
MIRT1473713	hsa-miR-670	CLIP-seq
MIRT1473714	hsa-miR-1263	CLIP-seq
MIRT1473715	hsa-miR-3609	CLIP-seq
MIRT1473716	hsa-miR-4252	CLIP-seq
MIRT1473717	hsa-miR-4786-3p	CLIP-seq
MIRT1473718	hsa-miR-548ah	CLIP-seq
MIRT1473719	hsa-miR-548t	CLIP-seq
MIRT2363094	hsa-miR-942	CLIP-seq
MIRT2657088	hsa-miR-1268	CLIP-seq
MIRT2657089	hsa-miR-1268b	CLIP-seq
MIRT2657090	hsa-miR-185	CLIP-seq
MIRT2657091	hsa-miR-3184	CLIP-seq
MIRT2657092	hsa-miR-3911	CLIP-seq
MIRT2657093	hsa-miR-423-5p	CLIP-seq
MIRT2657094	hsa-miR-4306	CLIP-seq
MIRT2657095	hsa-miR-4644	CLIP-seq
MIRT2657096	hsa-miR-4700-3p	CLIP-seq
MIRT2657097	hsa-miR-4768-3p	CLIP-seq
MIRT2657088	hsa-miR-1268	CLIP-seq
MIRT2657089	hsa-miR-1268b	CLIP-seq
MIRT2657090	hsa-miR-185	CLIP-seq
MIRT2657091	hsa-miR-3184	CLIP-seq
MIRT2657092	hsa-miR-3911	CLIP-seq
MIRT2657093	hsa-miR-423-5p	CLIP-seq
MIRT2657094	hsa-miR-4306	CLIP-seq
MIRT2657095	hsa-miR-4644	CLIP-seq
MIRT2657096	hsa-miR-4700-3p	CLIP-seq
MIRT2657097	hsa-miR-4768-3p	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0008194	Function	UDP-glycosyltransferase activity	IDA	22621930
GO:0008194	Function	UDP-glycosyltransferase activity	IEA
GO:0015020	Function	Glucuronosyltransferase activity	IBA
GO:0015020	Function	Glucuronosyltransferase activity	IDA	22621930
GO:0015020	Function	Glucuronosyltransferase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0043541	Component	UDP-N-acetylglucosamine transferase complex	IBA
GO:0043541	Component	UDP-N-acetylglucosamine transferase complex	IDA	22621930

MIM	HGNC	e!Ensembl
616383	26625	ENSG00000145626

Q6NUS8

Protein name

UDP-glucuronosyltransferase 3A1 (UDPGT 3A1) (EC 2.4.1.17)

Protein function

UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00201	UDPGT	23 → 522	UDP-glucoronosyl and UDP-glucosyl transferase	Family

Sequence

MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSG
KFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQ
CSYLLSRKDIMDSLKNENYDLVFVEAFDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSP
LSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHL
LLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAF
GSMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAH
PSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTL
TLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPW
HEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT

Sequence length

523

Interactions

View interactions

	Reactome
			Glucuronidation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BILIARY LIVER CIRRHOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY BILIARY CIRRHOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Cholestasis	Cholelithiasis	Pubtator	18981171	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gallstones	Gallstones	Pubtator	18981171	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis Biliary	Liver cirrhosis	Pubtator	33371893	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

UGT3A1 (UDP glycosyltransferase family 3 member A1)