UBR3 (ubiquitin protein ligase E3 component n-recognin 3)

Gene

• Entrez ID: 130507
• Gene name: Ubiquitin protein ligase E3 component n-recognin 3
• Gene symbol: UBR3
• Synonyms (NCBI Gene): ZNF650
• Chromosome: 2
• Chromosome location: 2q31.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016149	hsa-miR-615-3p	Sequencing	20371350
MIRT030893	hsa-miR-21-5p	Microarray	18591254
MIRT046319	hsa-miR-23b-3p	CLASH	23622248
MIRT086010	hsa-miR-107	HITS-CLIP	21572407
MIRT086009	hsa-miR-103a-3p	HITS-CLIP	21572407
MIRT086013	hsa-miR-424-5p	HITS-CLIP	21572407
MIRT086012	hsa-miR-195-5p	HITS-CLIP	21572407
MIRT086006	hsa-miR-16-5p	HITS-CLIP	21572407
MIRT086026	hsa-miR-6838-5p	HITS-CLIP	21572407
MIRT086011	hsa-miR-15b-5p	HITS-CLIP	21572407
MIRT086005	hsa-miR-15a-5p	HITS-CLIP	21572407
MIRT086014	hsa-miR-497-5p	HITS-CLIP	21572407
MIRT553118	hsa-miR-503-5p	HITS-CLIP	21572407
MIRT553117	hsa-miR-148a-5p	HITS-CLIP	21572407
MIRT086027	hsa-miR-7849-3p	HITS-CLIP	21572407
MIRT553116	hsa-miR-646	HITS-CLIP	21572407
MIRT553115	hsa-miR-3168	HITS-CLIP	21572407
MIRT553114	hsa-miR-4272	HITS-CLIP	21572407
MIRT553113	hsa-miR-5697	HITS-CLIP	21572407
MIRT553112	hsa-miR-567	HITS-CLIP	21572407
MIRT553111	hsa-miR-630	HITS-CLIP	21572407
MIRT086022	hsa-miR-4524a-5p	HITS-CLIP	21572407
MIRT086024	hsa-miR-4524b-5p	HITS-CLIP	21572407
MIRT086020	hsa-miR-3924	HITS-CLIP	21572407
MIRT086019	hsa-miR-1297	HITS-CLIP	21572407
MIRT086007	hsa-miR-26a-5p	HITS-CLIP	21572407
MIRT086008	hsa-miR-26b-5p	HITS-CLIP	21572407
MIRT086021	hsa-miR-4465	HITS-CLIP	21572407
MIRT086025	hsa-miR-4666b	HITS-CLIP	21572407
MIRT086018	hsa-miR-297	HITS-CLIP	21572407
MIRT086017	hsa-miR-374b-3p	HITS-CLIP	21572407
MIRT553110	hsa-miR-1305	HITS-CLIP	21572407
MIRT086010	hsa-miR-107	PAR-CLIP	21572407
MIRT086009	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT086013	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT086012	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT086006	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT086026	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT086011	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT086005	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT086014	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT553118	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT553117	hsa-miR-148a-5p	PAR-CLIP	21572407
MIRT086027	hsa-miR-7849-3p	PAR-CLIP	21572407
MIRT553116	hsa-miR-646	PAR-CLIP	21572407
MIRT553115	hsa-miR-3168	PAR-CLIP	21572407
MIRT553114	hsa-miR-4272	PAR-CLIP	21572407
MIRT553113	hsa-miR-5697	PAR-CLIP	21572407
MIRT553112	hsa-miR-567	PAR-CLIP	21572407
MIRT553111	hsa-miR-630	PAR-CLIP	21572407
MIRT086022	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT086024	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT086020	hsa-miR-3924	PAR-CLIP	21572407
MIRT086019	hsa-miR-1297	PAR-CLIP	21572407
MIRT086007	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT086008	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT086021	hsa-miR-4465	PAR-CLIP	21572407
MIRT086025	hsa-miR-4666b	PAR-CLIP	21572407
MIRT086018	hsa-miR-297	PAR-CLIP	21572407
MIRT086017	hsa-miR-374b-3p	PAR-CLIP	21572407
MIRT553110	hsa-miR-1305	PAR-CLIP	21572407
MIRT439351	hsa-miR-136-5p	HITS-CLIP	24374217
MIRT439351	hsa-miR-136-5p	HITS-CLIP	24374217
MIRT086010	hsa-miR-107	HITS-CLIP	21572407
MIRT086009	hsa-miR-103a-3p	HITS-CLIP	21572407
MIRT086013	hsa-miR-424-5p	HITS-CLIP	21572407
MIRT086012	hsa-miR-195-5p	HITS-CLIP	21572407
MIRT086006	hsa-miR-16-5p	HITS-CLIP	21572407
MIRT086026	hsa-miR-6838-5p	HITS-CLIP	21572407
MIRT086011	hsa-miR-15b-5p	HITS-CLIP	21572407
MIRT086005	hsa-miR-15a-5p	HITS-CLIP	21572407
MIRT086014	hsa-miR-497-5p	HITS-CLIP	21572407
MIRT553118	hsa-miR-503-5p	HITS-CLIP	21572407
MIRT553117	hsa-miR-148a-5p	HITS-CLIP	21572407
MIRT086027	hsa-miR-7849-3p	HITS-CLIP	21572407
MIRT553116	hsa-miR-646	HITS-CLIP	21572407
MIRT553115	hsa-miR-3168	HITS-CLIP	21572407
MIRT553114	hsa-miR-4272	HITS-CLIP	21572407
MIRT553113	hsa-miR-5697	HITS-CLIP	21572407
MIRT553112	hsa-miR-567	HITS-CLIP	21572407
MIRT553111	hsa-miR-630	HITS-CLIP	21572407
MIRT086022	hsa-miR-4524a-5p	HITS-CLIP	21572407
MIRT086024	hsa-miR-4524b-5p	HITS-CLIP	21572407
MIRT086020	hsa-miR-3924	HITS-CLIP	21572407
MIRT086019	hsa-miR-1297	HITS-CLIP	21572407
MIRT086007	hsa-miR-26a-5p	HITS-CLIP	21572407
MIRT086008	hsa-miR-26b-5p	HITS-CLIP	21572407
MIRT086021	hsa-miR-4465	HITS-CLIP	21572407
MIRT086025	hsa-miR-4666b	HITS-CLIP	21572407
MIRT086018	hsa-miR-297	HITS-CLIP	21572407
MIRT086017	hsa-miR-374b-3p	HITS-CLIP	21572407
MIRT553110	hsa-miR-1305	HITS-CLIP	21572407
MIRT086010	hsa-miR-107	PAR-CLIP	21572407
MIRT086009	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT086013	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT086012	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT086006	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT086026	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT086011	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT086005	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT086014	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT553118	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT553117	hsa-miR-148a-5p	PAR-CLIP	21572407
MIRT086027	hsa-miR-7849-3p	PAR-CLIP	21572407
MIRT553116	hsa-miR-646	PAR-CLIP	21572407
MIRT553115	hsa-miR-3168	PAR-CLIP	21572407
MIRT553114	hsa-miR-4272	PAR-CLIP	21572407
MIRT553113	hsa-miR-5697	PAR-CLIP	21572407
MIRT553112	hsa-miR-567	PAR-CLIP	21572407
MIRT553111	hsa-miR-630	PAR-CLIP	21572407
MIRT086022	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT086024	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT086020	hsa-miR-3924	PAR-CLIP	21572407
MIRT086019	hsa-miR-1297	PAR-CLIP	21572407
MIRT086007	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT086008	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT086021	hsa-miR-4465	PAR-CLIP	21572407
MIRT086025	hsa-miR-4666b	PAR-CLIP	21572407
MIRT086018	hsa-miR-297	PAR-CLIP	21572407
MIRT086017	hsa-miR-374b-3p	PAR-CLIP	21572407
MIRT553110	hsa-miR-1305	PAR-CLIP	21572407
MIRT1471391	hsa-miR-103a	CLIP-seq
MIRT1471392	hsa-miR-1200	CLIP-seq
MIRT1471393	hsa-miR-1237	CLIP-seq
MIRT1471394	hsa-miR-1248	CLIP-seq
MIRT1471395	hsa-miR-1253	CLIP-seq
MIRT1471396	hsa-miR-1324	CLIP-seq
MIRT1471397	hsa-miR-15a	CLIP-seq
MIRT1471398	hsa-miR-15b	CLIP-seq
MIRT1471399	hsa-miR-16	CLIP-seq
MIRT1471400	hsa-miR-1913	CLIP-seq
MIRT1471401	hsa-miR-195	CLIP-seq
MIRT1471402	hsa-miR-199a-5p	CLIP-seq
MIRT1471403	hsa-miR-199b-5p	CLIP-seq
MIRT1471404	hsa-miR-2053	CLIP-seq
MIRT1471405	hsa-miR-21	CLIP-seq
MIRT1471406	hsa-miR-2116	CLIP-seq
MIRT1471407	hsa-miR-214	CLIP-seq
MIRT1471408	hsa-miR-2277-3p	CLIP-seq
MIRT1471409	hsa-miR-23a	CLIP-seq
MIRT1471410	hsa-miR-23b	CLIP-seq
MIRT1471411	hsa-miR-23c	CLIP-seq
MIRT1471412	hsa-miR-26a	CLIP-seq
MIRT1471413	hsa-miR-26b	CLIP-seq
MIRT1471414	hsa-miR-27a	CLIP-seq
MIRT1471415	hsa-miR-27b	CLIP-seq
MIRT1471416	hsa-miR-3140-3p	CLIP-seq
MIRT1471417	hsa-miR-3143	CLIP-seq
MIRT1471418	hsa-miR-3150a-3p	CLIP-seq
MIRT1471419	hsa-miR-3175	CLIP-seq
MIRT1471420	hsa-miR-3177-3p	CLIP-seq
MIRT1471421	hsa-miR-320a	CLIP-seq
MIRT1471422	hsa-miR-320b	CLIP-seq
MIRT1471423	hsa-miR-320c	CLIP-seq
MIRT1471424	hsa-miR-320d	CLIP-seq
MIRT1471425	hsa-miR-324-3p	CLIP-seq
MIRT1471426	hsa-miR-3619-5p	CLIP-seq
MIRT1471427	hsa-miR-3662	CLIP-seq
MIRT1471428	hsa-miR-3671	CLIP-seq
MIRT1471429	hsa-miR-376a	CLIP-seq
MIRT1471430	hsa-miR-376b	CLIP-seq
MIRT1471431	hsa-miR-384	CLIP-seq
MIRT1471432	hsa-miR-3945	CLIP-seq
MIRT1471433	hsa-miR-409-3p	CLIP-seq
MIRT1471434	hsa-miR-424	CLIP-seq
MIRT1471435	hsa-miR-4251	CLIP-seq
MIRT1471436	hsa-miR-4253	CLIP-seq
MIRT1471437	hsa-miR-4263	CLIP-seq
MIRT1471438	hsa-miR-4287	CLIP-seq
MIRT1471439	hsa-miR-4307	CLIP-seq
MIRT1471440	hsa-miR-4324	CLIP-seq
MIRT1471441	hsa-miR-4429	CLIP-seq
MIRT1471442	hsa-miR-4434	CLIP-seq
MIRT1471443	hsa-miR-4452	CLIP-seq
MIRT1471444	hsa-miR-4469	CLIP-seq
MIRT1471445	hsa-miR-4477a	CLIP-seq
MIRT1471446	hsa-miR-4481	CLIP-seq
MIRT1471447	hsa-miR-4516	CLIP-seq
MIRT1471448	hsa-miR-4524	CLIP-seq
MIRT1471449	hsa-miR-4667-5p	CLIP-seq
MIRT1471450	hsa-miR-4677-5p	CLIP-seq
MIRT1471451	hsa-miR-4685-3p	CLIP-seq
MIRT1471452	hsa-miR-4699-5p	CLIP-seq
MIRT1471453	hsa-miR-4700-5p	CLIP-seq
MIRT1471454	hsa-miR-4705	CLIP-seq
MIRT1471455	hsa-miR-4713-5p	CLIP-seq
MIRT1471456	hsa-miR-4717-3p	CLIP-seq
MIRT1471457	hsa-miR-4745-5p	CLIP-seq
MIRT1471458	hsa-miR-4803	CLIP-seq
MIRT1471459	hsa-miR-497	CLIP-seq
MIRT1471460	hsa-miR-503	CLIP-seq
MIRT1471461	hsa-miR-5096	CLIP-seq
MIRT1471462	hsa-miR-513a-5p	CLIP-seq
MIRT1471463	hsa-miR-541	CLIP-seq
MIRT1471464	hsa-miR-544b	CLIP-seq
MIRT1471465	hsa-miR-545	CLIP-seq
MIRT1471466	hsa-miR-548p	CLIP-seq
MIRT1471467	hsa-miR-548t	CLIP-seq
MIRT1471468	hsa-miR-561	CLIP-seq
MIRT1471469	hsa-miR-569	CLIP-seq
MIRT1471470	hsa-miR-576-5p	CLIP-seq
MIRT1471471	hsa-miR-580	CLIP-seq
MIRT1471472	hsa-miR-590-5p	CLIP-seq
MIRT1471473	hsa-miR-600	CLIP-seq
MIRT1471474	hsa-miR-619	CLIP-seq
MIRT1471475	hsa-miR-629	CLIP-seq
MIRT1471476	hsa-miR-653	CLIP-seq
MIRT1471477	hsa-miR-654-5p	CLIP-seq
MIRT1471478	hsa-miR-657	CLIP-seq
MIRT1471479	hsa-miR-761	CLIP-seq
MIRT1471480	hsa-miR-939	CLIP-seq
MIRT2141876	hsa-miR-101	CLIP-seq
MIRT2141877	hsa-miR-1183	CLIP-seq
MIRT2141878	hsa-miR-1228	CLIP-seq
MIRT1471393	hsa-miR-1237	CLIP-seq
MIRT1471394	hsa-miR-1248	CLIP-seq
MIRT2141879	hsa-miR-1284	CLIP-seq
MIRT2141880	hsa-miR-129-5p	CLIP-seq
MIRT2141881	hsa-miR-144	CLIP-seq
MIRT1471409	hsa-miR-23a	CLIP-seq
MIRT1471410	hsa-miR-23b	CLIP-seq
MIRT1471411	hsa-miR-23c	CLIP-seq
MIRT2141882	hsa-miR-300	CLIP-seq
MIRT1471416	hsa-miR-3140-3p	CLIP-seq
MIRT2141883	hsa-miR-3646	CLIP-seq
MIRT2141884	hsa-miR-3660	CLIP-seq
MIRT2141885	hsa-miR-3684	CLIP-seq
MIRT1471429	hsa-miR-376a	CLIP-seq
MIRT1471430	hsa-miR-376b	CLIP-seq
MIRT2141886	hsa-miR-381	CLIP-seq
MIRT1471445	hsa-miR-4477a	CLIP-seq
MIRT1471446	hsa-miR-4481	CLIP-seq
MIRT2141887	hsa-miR-4526	CLIP-seq
MIRT1471452	hsa-miR-4699-5p	CLIP-seq
MIRT1471454	hsa-miR-4705	CLIP-seq
MIRT2141888	hsa-miR-4712-5p	CLIP-seq
MIRT1471456	hsa-miR-4717-3p	CLIP-seq
MIRT2141889	hsa-miR-4735-5p	CLIP-seq
MIRT2141890	hsa-miR-4742-3p	CLIP-seq
MIRT1471457	hsa-miR-4745-5p	CLIP-seq
MIRT2141891	hsa-miR-4760-3p	CLIP-seq
MIRT2141892	hsa-miR-4773	CLIP-seq
MIRT2141893	hsa-miR-4802-3p	CLIP-seq
MIRT2141894	hsa-miR-485-3p	CLIP-seq
MIRT2141895	hsa-miR-490-5p	CLIP-seq
MIRT2141896	hsa-miR-515-5p	CLIP-seq
MIRT1471465	hsa-miR-545	CLIP-seq
MIRT2141897	hsa-miR-590-3p	CLIP-seq
MIRT1471475	hsa-miR-629	CLIP-seq
MIRT2141898	hsa-miR-770-5p	CLIP-seq
MIRT2141876	hsa-miR-101	CLIP-seq
MIRT1471391	hsa-miR-103a	CLIP-seq
MIRT2141877	hsa-miR-1183	CLIP-seq
MIRT2141879	hsa-miR-1284	CLIP-seq
MIRT2141880	hsa-miR-129-5p	CLIP-seq
MIRT2141881	hsa-miR-144	CLIP-seq
MIRT1471397	hsa-miR-15a	CLIP-seq
MIRT1471398	hsa-miR-15b	CLIP-seq
MIRT1471399	hsa-miR-16	CLIP-seq
MIRT2362537	hsa-miR-186	CLIP-seq
MIRT1471401	hsa-miR-195	CLIP-seq
MIRT2362538	hsa-miR-2110	CLIP-seq
MIRT1471409	hsa-miR-23a	CLIP-seq
MIRT1471410	hsa-miR-23b	CLIP-seq
MIRT1471411	hsa-miR-23c	CLIP-seq
MIRT1471412	hsa-miR-26a	CLIP-seq
MIRT1471413	hsa-miR-26b	CLIP-seq
MIRT1471414	hsa-miR-27a	CLIP-seq
MIRT1471415	hsa-miR-27b	CLIP-seq
MIRT2362539	hsa-miR-3133	CLIP-seq
MIRT2362540	hsa-miR-329	CLIP-seq
MIRT2362541	hsa-miR-362-3p	CLIP-seq
MIRT2141884	hsa-miR-3660	CLIP-seq
MIRT1471427	hsa-miR-3662	CLIP-seq
MIRT2141885	hsa-miR-3684	CLIP-seq
MIRT2362542	hsa-miR-3941	CLIP-seq
MIRT1471434	hsa-miR-424	CLIP-seq
MIRT1471437	hsa-miR-4263	CLIP-seq
MIRT2362543	hsa-miR-4271	CLIP-seq
MIRT2362544	hsa-miR-4275	CLIP-seq
MIRT2362545	hsa-miR-4303	CLIP-seq
MIRT1471439	hsa-miR-4307	CLIP-seq
MIRT2362546	hsa-miR-4325	CLIP-seq
MIRT1471445	hsa-miR-4477a	CLIP-seq
MIRT1471448	hsa-miR-4524	CLIP-seq
MIRT2141887	hsa-miR-4526	CLIP-seq
MIRT2362547	hsa-miR-4639-3p	CLIP-seq
MIRT2362548	hsa-miR-4725-3p	CLIP-seq
MIRT2141890	hsa-miR-4742-3p	CLIP-seq
MIRT2362549	hsa-miR-4744	CLIP-seq
MIRT2141892	hsa-miR-4773	CLIP-seq
MIRT2362550	hsa-miR-4789-5p	CLIP-seq
MIRT2141893	hsa-miR-4802-3p	CLIP-seq
MIRT2141895	hsa-miR-490-5p	CLIP-seq
MIRT1471459	hsa-miR-497	CLIP-seq
MIRT2362551	hsa-miR-499-3p	CLIP-seq
MIRT2362552	hsa-miR-499a-3p	CLIP-seq
MIRT2362553	hsa-miR-501-3p	CLIP-seq
MIRT2362554	hsa-miR-502-3p	CLIP-seq
MIRT1471460	hsa-miR-503	CLIP-seq
MIRT1471461	hsa-miR-5096	CLIP-seq
MIRT1471462	hsa-miR-513a-5p	CLIP-seq
MIRT2362555	hsa-miR-548n	CLIP-seq
MIRT1471470	hsa-miR-576-5p	CLIP-seq
MIRT2362556	hsa-miR-603	CLIP-seq
MIRT2362557	hsa-miR-656	CLIP-seq
MIRT2362558	hsa-miR-890	CLIP-seq
MIRT2362559	hsa-miR-944	CLIP-seq
MIRT1471409	hsa-miR-23a	CLIP-seq
MIRT1471410	hsa-miR-23b	CLIP-seq
MIRT1471411	hsa-miR-23c	CLIP-seq
MIRT2396611	hsa-miR-433	CLIP-seq
MIRT1471437	hsa-miR-4263	CLIP-seq
MIRT2141889	hsa-miR-4735-5p	CLIP-seq
MIRT1471470	hsa-miR-576-5p	CLIP-seq
MIRT1471393	hsa-miR-1237	CLIP-seq
MIRT1471394	hsa-miR-1248	CLIP-seq
MIRT1471416	hsa-miR-3140-3p	CLIP-seq
MIRT2656479	hsa-miR-3163	CLIP-seq
MIRT2656480	hsa-miR-3674	CLIP-seq
MIRT1471429	hsa-miR-376a	CLIP-seq
MIRT1471430	hsa-miR-376b	CLIP-seq
MIRT2656481	hsa-miR-3978	CLIP-seq
MIRT2656482	hsa-miR-410	CLIP-seq
MIRT1471446	hsa-miR-4481	CLIP-seq
MIRT2656483	hsa-miR-451b	CLIP-seq
MIRT2656484	hsa-miR-4522	CLIP-seq
MIRT1471454	hsa-miR-4705	CLIP-seq
MIRT2656485	hsa-miR-4716-5p	CLIP-seq
MIRT1471456	hsa-miR-4717-3p	CLIP-seq
MIRT1471457	hsa-miR-4745-5p	CLIP-seq
MIRT2656486	hsa-miR-548c-3p	CLIP-seq
MIRT2656487	hsa-miR-587	CLIP-seq
MIRT1471473	hsa-miR-600	CLIP-seq
MIRT1471475	hsa-miR-629	CLIP-seq
MIRT2656488	hsa-miR-889	CLIP-seq
MIRT1471393	hsa-miR-1237	CLIP-seq
MIRT1471394	hsa-miR-1248	CLIP-seq
MIRT1471416	hsa-miR-3140-3p	CLIP-seq
MIRT1471429	hsa-miR-376a	CLIP-seq
MIRT1471430	hsa-miR-376b	CLIP-seq
MIRT1471446	hsa-miR-4481	CLIP-seq
MIRT1471454	hsa-miR-4705	CLIP-seq
MIRT1471456	hsa-miR-4717-3p	CLIP-seq
MIRT1471457	hsa-miR-4745-5p	CLIP-seq
MIRT1471475	hsa-miR-629	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IBA
GO:0001701	Process	In utero embryonic development	IEA
GO:0001967	Process	Suckling behavior	IEA
GO:0001967	Process	Suckling behavior	ISS
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0004842	Function	Ubiquitin-protein transferase activity	ISS
GO:0005515	Function	Protein binding	IPI	33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	ISS
GO:0007608	Process	Sensory perception of smell	IEA
GO:0007608	Process	Sensory perception of smell	ISS
GO:0008270	Function	Zinc ion binding	IEA
GO:0009792	Process	Embryo development ending in birth or egg hatching	IEA
GO:0009792	Process	Embryo development ending in birth or egg hatching	ISS
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0042048	Process	Olfactory behavior	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0045732	Process	Positive regulation of protein catabolic process	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0071596	Process	Ubiquitin-dependent protein catabolic process via the N-end rule pathway	IBA
GO:0071596	Process	Ubiquitin-dependent protein catabolic process via the N-end rule pathway	IEA
GO:1904878	Process	Negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	IEA

Other IDs

• MIM: 613831
• HGNC: 30467
• e!Ensembl: ENSG00000144357

Protein

• UniProt ID: Q6ZT12
• Protein name: E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)
• Protein function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity). Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and su
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02207	zf-UBR	119 → 187	Putative zinc finger in N-recognin (UBR box)	Family
  PF18995	PRT6_C	1423 → 1871	Proteolysis_6 C-terminal	Domain

• Sequence:

  MAAAAAAAVGGQQPSQPELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLS
  AERPLAAAAGGEDAAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALC
  GLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRE
  SGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNK
  VLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTSGLGENACVKKSHEKYLIAL
  KSSGLTYPEDKLVYGVQEPSAGTSSLAVQGFIGATGTLGQVDSSDEDDQDGSQGLGKRKR
  VKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFV
  QHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMES
  CLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTW
  MNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTR
  NVVRYCLEALQDWFDAINFVDEPAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSVLPDQ
  EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCA
  SRLDPDYFISSVFERFKVVDLLTMASQHQNTVLDAEHERSMLEGALTFLVILLSLRLHLG
  MSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPV
  FEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFPGNPW
  PPYKKRTSLHPSYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLE
  NSAEEESDEEASVGGPERCHDSWFPGSNLVSNMRHFINYVRVRVPETAPEVKRDSPASTS
  SDNLGSLQNSGTAQVFSLVAERRKKFQEIINRSSSEANQVVRPKTSSKWSAPGSAPQLTT
  AILEIKESILSLLIKLHHKLSGKQNSYYPPWLDDIEILIQPEIPKYSHGDGITAVERILL
  KAASQSRMNKRIIEEICRKVTPPVPPKKVTAAEKKTLDKEERRQKARERQQKLLAEFASR
  QKSFMETAMDVDSPENDIPMEITTAEPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQAS
  SVLGQCRDNVEPKKLPISEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGG
  VYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVE
  NNPWQRPSNKSIQDLIKEVEELQGRPGAFPSETNLSKEMESVMKDIKNTTQKKYRDYSKT
  PGSPDNDFLFMYSVARTNLELELIHRGGNLCSGGASTAGKRSCLNQLFHVLALHMRLYSI
  DSEYNPWRKLTQLEEMNPQLGYEEQQPEVPILYHDVTSLLLIQILMMPQPLRKDHFTCIV
  KVLFTLLYTQALAALSVKCSEEDRSAWKHAGALKKSTCDAEKSYEVLLSFVISELFKGKL
  YHEEGTQECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLPSCQEEEEFSV
  LASCLGLLPTFYQTEHPFISASCLDWPVPAFDIITQWCFEIKSFTERHAEQGKALLIQES
  KWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCE
  CVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKE
  RYKVLEQQWISHTFDHINKRWGPHYNGL

• Sequence length: 1888

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
IGA GLOMERULONEPHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UBR3-related disorder	Uncertain significance; Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	GWASCAT_DG	26503814		★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Iga nephropathy	Pubtator	37958966	Associate	★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial Aneurysm	BEFREE	26186006		★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial aneurysm	Pubtator	26186006	Associate	★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	19910543		★☆☆☆☆ Found in Text Mining only