Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1295
Gene name	Collagen type VIII alpha 1 chain
Gene symbol	COL8A1
Synonyms (NCBI Gene)	C3orf7
Chromosome	3
Chromosome location	3q12.1
Summary	This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrime

312

Show/Hide all (312)

miRTarBase ID	miRNA	Experiments	Reference
MIRT519131	hsa-miR-8485	HITS-CLIP	21572407
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT510125	hsa-miR-1295b-3p	HITS-CLIP	21572407
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT519131	hsa-miR-8485	HITS-CLIP	23313552
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT612016	hsa-miR-3939	HITS-CLIP	23313552
MIRT510125	hsa-miR-1295b-3p	HITS-CLIP	23313552
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23313552
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT675663	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675662	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT675661	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675660	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675659	hsa-miR-564	HITS-CLIP	23824327
MIRT675658	hsa-miR-4743-5p	HITS-CLIP	23824327
MIRT675657	hsa-miR-4284	HITS-CLIP	23824327
MIRT675656	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675655	hsa-miR-7977	HITS-CLIP	23824327
MIRT675654	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	PAR-CLIP	21572407
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	21572407
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT519131	hsa-miR-8485	PAR-CLIP	23446348
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT461372	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT461371	hsa-miR-4779	PAR-CLIP	23592263
MIRT461370	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT461369	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT461368	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT461367	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT461366	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT461365	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT461364	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT461363	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT461362	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT461361	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT461359	hsa-miR-4458	PAR-CLIP	23592263
MIRT461360	hsa-miR-4500	PAR-CLIP	23592263
MIRT461358	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT461357	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT461355	hsa-miR-6086	PAR-CLIP	23592263
MIRT461356	hsa-miR-4451	PAR-CLIP	23592263
MIRT461353	hsa-miR-4266	PAR-CLIP	23592263
MIRT461354	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT461352	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	27418678
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	27418678
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	27418678
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	27418678
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	27418678
MIRT612016	hsa-miR-3939	HITS-CLIP	27418678
MIRT612016	hsa-miR-3939	HITS-CLIP	27418678
MIRT612016	hsa-miR-3939	HITS-CLIP	27418678
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT519131	hsa-miR-8485	HITS-CLIP	27418678
MIRT519131	hsa-miR-8485	HITS-CLIP	27418678
MIRT519131	hsa-miR-8485	HITS-CLIP	21572407
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT510125	hsa-miR-1295b-3p	HITS-CLIP	21572407
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT519131	hsa-miR-8485	HITS-CLIP	23313552
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT612016	hsa-miR-3939	HITS-CLIP	23313552
MIRT510125	hsa-miR-1295b-3p	HITS-CLIP	23313552
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23313552
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT675663	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675662	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT675661	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675660	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675659	hsa-miR-564	HITS-CLIP	23824327
MIRT675658	hsa-miR-4743-5p	HITS-CLIP	23824327
MIRT675657	hsa-miR-4284	HITS-CLIP	23824327
MIRT675656	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675655	hsa-miR-7977	HITS-CLIP	23824327
MIRT675654	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT510123	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	HITS-CLIP	23824327
MIRT510127	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612016	hsa-miR-3939	HITS-CLIP	23824327
MIRT510126	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT612015	hsa-miR-3186-3p	HITS-CLIP	23824327
MIRT510124	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT519131	hsa-miR-8485	PAR-CLIP	21572407
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	21572407
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT519131	hsa-miR-8485	PAR-CLIP	23446348
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT510127	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT510125	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT510126	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT510124	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT510123	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT461372	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT461371	hsa-miR-4779	PAR-CLIP	23592263
MIRT461370	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT461369	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT461368	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT461367	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT461366	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT461365	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT461364	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT461363	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT461362	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT461361	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT461359	hsa-miR-4458	PAR-CLIP	23592263
MIRT461360	hsa-miR-4500	PAR-CLIP	23592263
MIRT461358	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT461357	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT461355	hsa-miR-6086	PAR-CLIP	23592263
MIRT461356	hsa-miR-4451	PAR-CLIP	23592263
MIRT461353	hsa-miR-4266	PAR-CLIP	23592263
MIRT461354	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT461352	hsa-miR-6516-5p	PAR-CLIP	23592263

Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEA
GO:0001935	Process	Endothelial cell proliferation	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 29892012, 31515488, 32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005581	Component	Collagen trimer	IEA
GO:0005591	Component	Collagen type VIII trimer	TAS	2029894, 9438378
GO:0005604	Component	Basement membrane	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0007155	Process	Cell adhesion	IEA
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IEA
GO:0030020	Function	Extracellular matrix structural constituent conferring tensile strength	IBA
GO:0030020	Function	Extracellular matrix structural constituent conferring tensile strength	RCA	20551380, 23979707, 25037231, 27068509, 27559042, 28327460, 28675934
GO:0031012	Component	Extracellular matrix	HDA	20551380
GO:0031012	Component	Extracellular matrix	HDA	23979707, 25037231, 27068509, 27559042, 28327460, 28675934
GO:0031012	Component	Extracellular matrix	IBA
GO:0035987	Process	Endodermal cell differentiation	IEP	23154389
GO:0048593	Process	Camera-type eye morphogenesis	IEA

MIM	HGNC	e!Ensembl
120251	2215	ENSG00000144810

P27658

Protein name

Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin]

Protein function

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascul

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01391	Collagen	157 → 214	Collagen triple helix repeat (20 copies)	Repeat
PF01391	Collagen	207 → 271	Collagen triple helix repeat (20 copies)	Repeat
PF00386	C1q	617 → 741	C1q domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair folli

Sequence

MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH
MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ
GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE
IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK
GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP
IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG
DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG
PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG
PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL
HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA
YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV
YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS
EQAAGLYAGQYVHSSFSGYLLYPM

Sequence length

744

Interactions

View interactions

	KEGG		Reactome
	Protein digestion and absorption		Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (12)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATROPHIC MACULAR DEGENERATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC KIDNEY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COL8A1-related disorder	Likely benign; Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL ABNORMALITIES	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL ABNORMALITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART FAILURE, DIASTOLIC	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPEN-ANGLE GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
WET MACULAR DEGENERATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (50)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	29497907		★★★★★ ★☆☆☆☆ Found in Text Mining only
Age related macular degeneration	Age-related macular degeneration	BEFREE	21665990, 29197628, 29706360		★★★★★ ★☆☆☆☆ Found in Text Mining only
Age related macular degeneration	Age-related macular degeneration	GWASDB_DG	21665990, 23455636		★★★★★ ★☆☆☆☆ Found in Text Mining only
Age related macular degeneration	Age-related macular degeneration	GWASCAT_DG	23455636, 26691988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Psoriatic	Psoriatic arthritis	Pubtator	32326527	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	GWASCAT_DG	29059683		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	32311840	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Dilated	Dilated cardiomyopathy	Pubtator	27936202	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Choroidal Neovascularization	Choroidal neovascularization	Pubtator	27643879, 32730261	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cleft Lip	Cleft lip	Pubtator	23512105	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cleft Palate	Cleft palate	Pubtator	23512105	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital keratoglobus	Congenital Keratoglobus	BEFREE	17721297		★★★★★ ★☆☆☆☆ Found in Text Mining only
Corneal dystrophy	Corneal Dystrophy	BEFREE	16936088		★★★★★ ★☆☆☆☆ Found in Text Mining only
Corneal Neovascularization	Corneal neovascularization	Pubtator	24498017	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis Atopic	Atopic dermatitis	Pubtator	31275967	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	24145053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	36949528	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	17888087		★★★★★ ★☆☆☆☆ Found in Text Mining only
Drusen	Drusen	BEFREE	29706360		★★★★★ ★☆☆☆☆ Found in Text Mining only
Exudative age-related macular degeneration	Exudative Macular Degeneration	BEFREE	26617902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Exudative age-related macular degeneration	Exudative Macular Degeneration	GWASCAT_DG	26691988		★★★★★ ★☆☆☆☆ Found in Text Mining only
exudative macular degeneration	Exudative macular degeneration	GWASCAT_DG	26691988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Focal glomerulosclerosis	Glomerulosclerosis	BEFREE	17888087		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fuchs Endothelial Dystrophy	Fuchs Endothelial Dystrophy	BEFREE	16936088		★★★★★ ★☆☆☆☆ Found in Text Mining only
Geographic Atrophy	Geographic Atrophy	GWASCAT_DG	26691988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gilles de la Tourette syndrome	Tourette Syndrome	BEFREE	23533600		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glaucoma, Primary Open Angle	Glaucoma	BEFREE	21139683		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	35456975	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	38225203	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glycogen Storage Disease Type II	Glycogen storage disease	Pubtator	24498017	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glycogen storage disease type II	Glycogen Storage Disease	BEFREE	29197628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	39563337	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Failure, Diastolic	Heart Failure	CTD_human_DG	29556499		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	BEFREE	27643879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Keratoconus	Keratoconus	BEFREE	17721297		★★★★★ ★☆☆☆☆ Found in Text Mining only
Laryngeal Neoplasms	Laryngeal neoplasm	Pubtator	36033826	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Nephritis	Lupus nephritis	Pubtator	26110394	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Macular Degeneration	Macular degeneration	Pubtator	26961928, 30389371, 30934838, 31191752	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	BEFREE	22678500, 27643879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	Pubtator	22678500, 27643879	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	Pubtator	32326527	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinal Diseases	Retinal Diseases	BEFREE	12540964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Severe myopia	Myopia	BEFREE	27643879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	34999279	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	32293980, 34338150, 35774273	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Papillary thyroid cancer	Pubtator	40157360	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tourette Syndrome	Tourette syndrome	Pubtator	23533600	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	30723390	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ventricular Dysfunction Left	Ventricular dysfunction	Pubtator	27936202	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ventricular Remodeling	Ventricular remodeling	Pubtator	27936202	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

COL8A1 (collagen type VIII alpha 1 chain)