EDARADD (EDAR associated via death domain)

Gene

• Entrez ID: 128178
• Gene name: EDAR associated via death domain
• Gene symbol: EDARADD
• Synonyms (NCBI Gene): CR, ECTD11A, ECTD11B, ED3, EDA3
• Chromosome: 1
• Chromosome location: 1q42.3-q43
• Summary: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs74315309	G>A	Pathogenic	Missense variant, coding sequence variant
rs121908116	T>G	Pathogenic	Missense variant, coding sequence variant
rs397515575	AACGGT>-	Pathogenic	Coding sequence variant, inframe deletion
rs766500689	C>A,T	Pathogenic	Stop gained, synonymous variant, coding sequence variant
rs879255553	G>A	Pathogenic	Splice donor variant
rs879255629	G>A	Pathogenic	Missense variant, coding sequence variant
rs954823206	G>A	Likely-pathogenic	Coding sequence variant, stop gained
rs1553271837	A>G	Likely-pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT043891	hsa-miR-378a-3p	CLASH	23622248
MIRT040816	hsa-miR-18a-3p	CLASH	23622248
MIRT638797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT638796	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT638795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT638794	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT638793	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT638792	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT638791	hsa-miR-3182	HITS-CLIP	23824327
MIRT638790	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT638789	hsa-miR-4284	HITS-CLIP	23824327
MIRT638788	hsa-miR-3686	HITS-CLIP	23824327
MIRT638787	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456954	hsa-miR-4437	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT456952	hsa-miR-4674	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	22012620
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	22012620
MIRT186098	hsa-miR-764	PAR-CLIP	22012620
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT456954	hsa-miR-4437	PAR-CLIP	23446348
MIRT456952	hsa-miR-4674	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	24398324
MIRT186099	hsa-miR-4436a	PAR-CLIP	24398324
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	24398324
MIRT186098	hsa-miR-764	PAR-CLIP	24398324
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT456954	hsa-miR-4437	PAR-CLIP	23592263
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	23592263
MIRT456952	hsa-miR-4674	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	27292025
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	27292025
MIRT186097	hsa-miR-552-3p	PAR-CLIP	27292025
MIRT186098	hsa-miR-764	PAR-CLIP	27292025
MIRT638797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT638796	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT638795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT638794	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT638793	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT638792	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT638791	hsa-miR-3182	HITS-CLIP	23824327
MIRT638790	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT638789	hsa-miR-4284	HITS-CLIP	23824327
MIRT638788	hsa-miR-3686	HITS-CLIP	23824327
MIRT638787	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456954	hsa-miR-4437	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT456952	hsa-miR-4674	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	22012620
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	22012620
MIRT186098	hsa-miR-764	PAR-CLIP	22012620
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT456954	hsa-miR-4437	PAR-CLIP	23446348
MIRT456952	hsa-miR-4674	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	24398324
MIRT186099	hsa-miR-4436a	PAR-CLIP	24398324
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	24398324
MIRT186098	hsa-miR-764	PAR-CLIP	24398324
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT456954	hsa-miR-4437	PAR-CLIP	23592263
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	23592263
MIRT456952	hsa-miR-4674	PAR-CLIP	23592263
MIRT952018	hsa-miR-1237	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952020	hsa-miR-193a-3p	CLIP-seq
MIRT952021	hsa-miR-193b	CLIP-seq
MIRT952022	hsa-miR-2355-5p	CLIP-seq
MIRT952023	hsa-miR-28-5p	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952025	hsa-miR-3139	CLIP-seq
MIRT952026	hsa-miR-3150b-3p	CLIP-seq
MIRT952027	hsa-miR-3185	CLIP-seq
MIRT952028	hsa-miR-3187-3p	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952030	hsa-miR-323b-5p	CLIP-seq
MIRT952031	hsa-miR-3613-5p	CLIP-seq
MIRT952032	hsa-miR-3926	CLIP-seq
MIRT952033	hsa-miR-4267	CLIP-seq
MIRT952034	hsa-miR-4268	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT952036	hsa-miR-4330	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT952038	hsa-miR-4480	CLIP-seq
MIRT952039	hsa-miR-4487	CLIP-seq
MIRT952040	hsa-miR-4511	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952043	hsa-miR-4689	CLIP-seq
MIRT952044	hsa-miR-4701-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT952046	hsa-miR-4727-5p	CLIP-seq
MIRT952047	hsa-miR-4728-3p	CLIP-seq
MIRT952048	hsa-miR-4757-5p	CLIP-seq
MIRT952049	hsa-miR-4769-3p	CLIP-seq
MIRT952050	hsa-miR-4784	CLIP-seq
MIRT952051	hsa-miR-4793-3p	CLIP-seq
MIRT952052	hsa-miR-4793-5p	CLIP-seq
MIRT952053	hsa-miR-518e	CLIP-seq
MIRT952054	hsa-miR-548s	CLIP-seq
MIRT952055	hsa-miR-588	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT952058	hsa-miR-708	CLIP-seq
MIRT952059	hsa-miR-769-5p	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT952061	hsa-miR-125a-5p	CLIP-seq
MIRT952062	hsa-miR-125b	CLIP-seq
MIRT952063	hsa-miR-127-5p	CLIP-seq
MIRT952064	hsa-miR-1276	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952065	hsa-miR-135a	CLIP-seq
MIRT952066	hsa-miR-135b	CLIP-seq
MIRT952067	hsa-miR-184	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952072	hsa-miR-3120-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT952076	hsa-miR-323-5p	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952078	hsa-miR-3622b-5p	CLIP-seq
MIRT952079	hsa-miR-3664-5p	CLIP-seq
MIRT952080	hsa-miR-3675-3p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT952083	hsa-miR-4292	CLIP-seq
MIRT952084	hsa-miR-4308	CLIP-seq
MIRT952085	hsa-miR-4319	CLIP-seq
MIRT952086	hsa-miR-4327	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT952087	hsa-miR-4475	CLIP-seq
MIRT952088	hsa-miR-4639-3p	CLIP-seq
MIRT952089	hsa-miR-4640-5p	CLIP-seq
MIRT952090	hsa-miR-4652-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT952093	hsa-miR-4720-5p	CLIP-seq
MIRT952094	hsa-miR-4726-5p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952096	hsa-miR-4732-3p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT952098	hsa-miR-4799-3p	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952100	hsa-miR-490-5p	CLIP-seq
MIRT952101	hsa-miR-526b	CLIP-seq
MIRT952102	hsa-miR-580	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT952104	hsa-miR-661	CLIP-seq
MIRT952105	hsa-miR-670	CLIP-seq
MIRT952106	hsa-miR-876-3p	CLIP-seq
MIRT952061	hsa-miR-125a-5p	CLIP-seq
MIRT952062	hsa-miR-125b	CLIP-seq
MIRT952063	hsa-miR-127-5p	CLIP-seq
MIRT952064	hsa-miR-1276	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952065	hsa-miR-135a	CLIP-seq
MIRT952066	hsa-miR-135b	CLIP-seq
MIRT1548131	hsa-miR-1827	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952022	hsa-miR-2355-5p	CLIP-seq
MIRT1548132	hsa-miR-2682	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT1548133	hsa-miR-3612	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952078	hsa-miR-3622b-5p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT1548134	hsa-miR-3945	CLIP-seq
MIRT1548135	hsa-miR-4253	CLIP-seq
MIRT1548136	hsa-miR-4273	CLIP-seq
MIRT1548137	hsa-miR-4289	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT952085	hsa-miR-4319	CLIP-seq
MIRT952086	hsa-miR-4327	CLIP-seq
MIRT1548138	hsa-miR-4328	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT1548139	hsa-miR-4459	CLIP-seq
MIRT1548140	hsa-miR-4468	CLIP-seq
MIRT952087	hsa-miR-4475	CLIP-seq
MIRT1548141	hsa-miR-449c	CLIP-seq
MIRT952089	hsa-miR-4640-5p	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT1548142	hsa-miR-4677-3p	CLIP-seq
MIRT1548143	hsa-miR-4677-5p	CLIP-seq
MIRT1548144	hsa-miR-4679	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT1548145	hsa-miR-4695-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT1548146	hsa-miR-4722-5p	CLIP-seq
MIRT952094	hsa-miR-4726-5p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952096	hsa-miR-4732-3p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT1548147	hsa-miR-4753-3p	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT1548149	hsa-miR-650	CLIP-seq
MIRT952104	hsa-miR-661	CLIP-seq
MIRT952105	hsa-miR-670	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT1548150	hsa-miR-924	CLIP-seq
MIRT1548151	hsa-miR-942	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952023	hsa-miR-28-5p	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952025	hsa-miR-3139	CLIP-seq
MIRT952026	hsa-miR-3150b-3p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT1981943	hsa-miR-3180-5p	CLIP-seq
MIRT952027	hsa-miR-3185	CLIP-seq
MIRT952028	hsa-miR-3187-3p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT952030	hsa-miR-323b-5p	CLIP-seq
MIRT952031	hsa-miR-3613-5p	CLIP-seq
MIRT1981944	hsa-miR-3614-3p	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT952032	hsa-miR-3926	CLIP-seq
MIRT1981945	hsa-miR-421	CLIP-seq
MIRT952033	hsa-miR-4267	CLIP-seq
MIRT952034	hsa-miR-4268	CLIP-seq
MIRT1548136	hsa-miR-4273	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT1548138	hsa-miR-4328	CLIP-seq
MIRT952036	hsa-miR-4330	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT1981946	hsa-miR-4470	CLIP-seq
MIRT952039	hsa-miR-4487	CLIP-seq
MIRT952040	hsa-miR-4511	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT1548142	hsa-miR-4677-3p	CLIP-seq
MIRT1548143	hsa-miR-4677-5p	CLIP-seq
MIRT1548144	hsa-miR-4679	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT952043	hsa-miR-4689	CLIP-seq
MIRT952044	hsa-miR-4701-5p	CLIP-seq
MIRT1981947	hsa-miR-4722-3p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT1548147	hsa-miR-4753-3p	CLIP-seq
MIRT1981948	hsa-miR-4762-3p	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT952050	hsa-miR-4784	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952053	hsa-miR-518e	CLIP-seq
MIRT1981950	hsa-miR-520a-5p	CLIP-seq
MIRT1981951	hsa-miR-525-5p	CLIP-seq
MIRT952054	hsa-miR-548s	CLIP-seq
MIRT952055	hsa-miR-588	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952058	hsa-miR-708	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT1548151	hsa-miR-942	CLIP-seq
MIRT952018	hsa-miR-1237	CLIP-seq
MIRT2216811	hsa-miR-1245b-5p	CLIP-seq
MIRT2216812	hsa-miR-125a-3p	CLIP-seq
MIRT2216813	hsa-miR-1260	CLIP-seq
MIRT2216814	hsa-miR-1260b	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT2216815	hsa-miR-134	CLIP-seq
MIRT2216816	hsa-miR-185	CLIP-seq
MIRT2216817	hsa-miR-188-3p	CLIP-seq
MIRT952020	hsa-miR-193a-3p	CLIP-seq
MIRT952021	hsa-miR-193b	CLIP-seq
MIRT2216818	hsa-miR-214	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT2216819	hsa-miR-3118	CLIP-seq
MIRT2216820	hsa-miR-3136-5p	CLIP-seq
MIRT2216821	hsa-miR-3142	CLIP-seq
MIRT2216822	hsa-miR-3156-3p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT2216823	hsa-miR-3619-5p	CLIP-seq
MIRT2216824	hsa-miR-383	CLIP-seq
MIRT1981945	hsa-miR-421	CLIP-seq
MIRT2216825	hsa-miR-4291	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT2216826	hsa-miR-4306	CLIP-seq
MIRT2216827	hsa-miR-4320	CLIP-seq
MIRT2216828	hsa-miR-4433	CLIP-seq
MIRT2216829	hsa-miR-4439	CLIP-seq
MIRT1548139	hsa-miR-4459	CLIP-seq
MIRT2216830	hsa-miR-4513	CLIP-seq
MIRT2216831	hsa-miR-4644	CLIP-seq
MIRT2216832	hsa-miR-4645-5p	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT2216833	hsa-miR-4650-5p	CLIP-seq
MIRT2216834	hsa-miR-4654	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT2216835	hsa-miR-4673	CLIP-seq
MIRT2216836	hsa-miR-4676-5p	CLIP-seq
MIRT2216837	hsa-miR-4691-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT2216838	hsa-miR-4709-5p	CLIP-seq
MIRT2216839	hsa-miR-4733-3p	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT2216840	hsa-miR-4768-3p	CLIP-seq
MIRT2216841	hsa-miR-4769-5p	CLIP-seq
MIRT2216842	hsa-miR-4772-5p	CLIP-seq
MIRT952051	hsa-miR-4793-3p	CLIP-seq
MIRT952052	hsa-miR-4793-5p	CLIP-seq
MIRT2216843	hsa-miR-575	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT2216844	hsa-miR-619	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT2216845	hsa-miR-662	CLIP-seq
MIRT2216846	hsa-miR-761	CLIP-seq
MIRT952059	hsa-miR-769-5p	CLIP-seq
MIRT2216847	hsa-miR-922	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT2216815	hsa-miR-134	CLIP-seq
MIRT2216819	hsa-miR-3118	CLIP-seq
MIRT2216820	hsa-miR-3136-5p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT2216829	hsa-miR-4439	CLIP-seq
MIRT2216830	hsa-miR-4513	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT2520853	hsa-miR-3155	CLIP-seq
MIRT2520854	hsa-miR-3155b	CLIP-seq
MIRT2520855	hsa-miR-4536	CLIP-seq
MIRT2520856	hsa-miR-484	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq
MIRT2520853	hsa-miR-3155	CLIP-seq
MIRT2520854	hsa-miR-3155b	CLIP-seq
MIRT2679747	hsa-miR-4323	CLIP-seq
MIRT2520855	hsa-miR-4536	CLIP-seq
MIRT2679748	hsa-miR-4726-3p	CLIP-seq
MIRT2216839	hsa-miR-4733-3p	CLIP-seq
MIRT2679749	hsa-miR-4758-3p	CLIP-seq
MIRT2520856	hsa-miR-484	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 31515488
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0030154	Process	Cell differentiation	IEA

Other IDs

• MIM: 606603
• HGNC: 14341
• e!Ensembl: ENSG00000186197

Protein

• UniProt ID: Q8WWZ3
• Protein name: Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog)
• Protein function: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00531	Death	122 → 199	Death domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.
• Sequence:

  MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTI
  TLNCPRNSDMKNQGEENGFPDSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD
  LLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLM
  ELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF

• Sequence length: 215

Pathways

KEGG:

NF-kappa B signaling pathway

Reactome:

TNFs bind their physiological receptors

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant	Likely pathogenic; Pathogenic	rs74315309, rs121908116	RCV001729334 RCV000055985	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Ectodermal dysplasia 11A, hypohidrotic/hair/tooth type, autosomal dominant	Likely pathogenic; Pathogenic	rs2103042605, rs74315309, rs121908116, rs879255629, rs2526890961, rs954823206	RCV001807985 RCV004798715 RCV000004408 RCV003765486 RCV003794981 RCV000549383	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Likely pathogenic	rs879255629	RCV000239549	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive	Likely pathogenic; Pathogenic	rs74315309, rs2526927321, rs879255629, rs879255553, rs766500689, rs2526890961, rs954823206, rs1657345576, rs200017138	RCV000004407 RCV003238157 RCV003765486 RCV000239464 RCV003338495 RCV003794981 RCV000549383 RCV001291625 RCV001291626	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Tooth agenesis	Likely pathogenic	rs1030214435	RCV001269383	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AUTOIMMUNE THYROID DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTOSOMAL DOMINANT HYPOHIDROTIC ECTODERMAL DYSPLASIA	—	GenCC, Orphanet GenCC, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTOSOMAL DOMINANT HYPOHIDROTIC ECTODERMAL DYSPLASIA SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTOSOMAL RECESSIVE HYPOHIDROTIC ECTODERMAL DYSPLASIA	—	GenCC, Orphanet GenCC, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRIST-SIEMENS-TOURAINE SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal dysplasia	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive	Likely benign; Uncertain significance	ClinVar ClinVar, Disgenet, HPO ClinVar, Disgenet, HPO ClinVar, Disgenet, HPO	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
ECTODERMAL DYSPLASIA 3, ANHIDROTIC	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ECTODERMAL DYSPLASIA, HYPOHIDROTIC, AUTOSOMAL RECESSIVE	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EDARADD-related disorder	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypohidrotic ectodermal dysplasia	Uncertain significance; Benign; Likely benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypohidrotic Ectodermal Dysplasia, Recessive	Benign; Likely benign; Conflicting classifications of pathogenicity; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTHYROIDISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UPPER AERODIGESTIVE TRACT NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alopecia	Alopecia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Anhidrosis	Anhidrosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Anhydrotic Ectodermal Dysplasias	Hypohidrotic ectodermal dysplasia	BEFREE	17354266, 21771270		★☆☆☆☆ Found in Text Mining only
Anodontia	Anodontia	Pubtator	22581971, 27665865	Associate	★☆☆☆☆ Found in Text Mining only
Autosomal dominant hypohidrotic ectodermal dysplasia	Hypohidrotic ectodermal dysplasia	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder)	Hypohidrotic Ectodermal Dysplasia, X-Linked	ORPHANET_DG			★☆☆☆☆ Found in Text Mining only
Autosomal recessive hypohidrotic ectodermal dysplasia	Hypohidrotic ectodermal dysplasia	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bloch Sulzberger syndrome	Incontinentia pigmenti syndrome	BEFREE	19504606		★☆☆☆☆ Found in Text Mining only
Christ-Siemens-Touraine syndrome	Hypohidrotic Ectodermal Dysplasia, X-Linked	BEFREE	11780064, 17354266, 18231121, 19504606, 20222921, 20477971, 21626677, 21771270, 21876339, 22013926, 26440664		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Christ-Siemens-Touraine syndrome	Hypohidrotic Ectodermal Dysplasia, X-Linked	GENOMICS_ENGLAND_DG	20222921, 25206167		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Christ-Siemens-Touraine syndrome	Hypohidrotic Ectodermal Dysplasia, X-Linked	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37838280	Stimulate	★☆☆☆☆ Found in Text Mining only
Dental Caries	Dental caries	Pubtator	21940522, 39543892	Associate	★☆☆☆☆ Found in Text Mining only
Developmental absence of tooth	Anodontia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	28736931		★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia	Ectodermal Dysplasia	BEFREE	19504606		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia	Ectodermal dysplasia	Pubtator	22581971, 30974434, 34573371, 37673591	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia	Ectodermal Dysplasia	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia 1 Anhidrotic	Ectodermal dysplasia	Pubtator	33205897	Associate	★☆☆☆☆ Found in Text Mining only
ECTODERMAL DYSPLASIA 10A, HYPOHIDROTIC/HAIR/NAIL TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	BEFREE	15721144, 16029325, 17478381, 18231121, 19504606, 20222921, 22013926, 26440664, 31245878, 31310406, 31796081		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal Dysplasia	BEFREE	15721144, 16029325, 17478381, 18231121, 19504606, 20222921, 22013926, 26440664, 31245878, 31310406, 31796081		★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal Dysplasia	CLINVAR_DG			★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	BEFREE	15721144, 16029325, 17478381, 18231121, 19504606, 20222921, 22013926, 26440664, 31245878, 31310406, 31796081		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	UNIPROT_DG	17354266, 20979233		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	GENOMICS_ENGLAND_DG	20222921, 25206167		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	CTD_human_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal dysplasia	CLINVAR_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Ectodermal Dysplasia	CLINVAR_DG			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal dysplasia	UNIPROT_DG	11780064, 17354266, 20222921		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal dysplasia	BEFREE	15721144, 16029325, 17478381, 18231121, 19504606, 20222921, 22013926, 26440664, 31245878, 31310406, 31796081		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal dysplasia	GENOMICS_ENGLAND_DG	20222921, 25206167		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE	Ectodermal dysplasia	CLINVAR_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Ectodermal Dysplasia 3, Anhidrotic	Ectodermal Dysplasia	CTD_human_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia Hypohidrotic Autosomal Recessive	Ectodermal dysplasia	Pubtator	30974434	Associate	★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive	Ectodermal dysplasia	BEFREE	21332691		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive	Ectodermal dysplasia	ORPHANET_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive	Ectodermal dysplasia	CTD_human_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Eczema	Eczema	HPO_DG			★☆☆☆☆ Found in Text Mining only
Frontal bossing	Frontal bossing	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypodontia	Hypodontia	BEFREE	21626677, 24312213		★☆☆☆☆ Found in Text Mining only
Hypodontia	Hypodontia	ORPHANET_DG			★☆☆☆☆ Found in Text Mining only
Hypodontia	Hypodontia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypohidrosis	Hypohidrosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypoplasia of nipple	Hypoplasia Of Nipple	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypoplasia of teeth	Hypoplasia of teeth	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypoplasia of the maxilla	Hypoplasia of the maxilla	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	GWASCAT_DG	30595370		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypotrichosis	Hypotrichosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Microdontia (disorder)	Microdontia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	HPO_DG			★☆☆☆☆ Found in Text Mining only
NAIL DISORDER, NONSYNDROMIC CONGENITAL, 9	Nail Diseases	HPO_DG			★☆☆☆☆ Found in Text Mining only
Nail dysplasia	Nail dysplasia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	26449251		★☆☆☆☆ Found in Text Mining only
Oligodontia	Oligodontia	BEFREE	21626677, 24312213		★☆☆☆☆ Found in Text Mining only
Oligodontia	Oligodontia	ORPHANET_DG			★☆☆☆☆ Found in Text Mining only
Oligodontia	Oligodontia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Oropharyngeal Neoplasms	Oropharyngeal neoplasm	Pubtator	37175405	Associate	★☆☆☆☆ Found in Text Mining only
Peg-shaped teeth	Peg-Shaped Teeth	HPO_DG			★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	32188493	Associate	★☆☆☆☆ Found in Text Mining only
Rhinitis	Rhinitis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	36335337	Associate	★☆☆☆☆ Found in Text Mining only