Gene Gene information from NCBI Gene database.
Entrez ID 126767
Gene name Arylacetamide deacetylase like 3
Gene symbol AADACL3
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1p36.21
miRNA miRNA information provided by mirtarbase database.
93
miRTarBase ID miRNA Experiments Reference
MIRT045321 hsa-miR-185-5p CLASH 23622248
MIRT038610 hsa-miR-186-3p CLASH 23622248
MIRT647271 hsa-miR-515-5p HITS-CLIP 23824327
MIRT647270 hsa-miR-519e-5p HITS-CLIP 23824327
MIRT647269 hsa-miR-629-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
3
GO ID Ontology Definition Evidence Reference
GO:0016020 Component Membrane IEA
GO:0016787 Function Hydrolase activity IEA
GO:0052689 Function Carboxylic ester hydrolase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5VUY0
Protein name Arylacetamide deacetylase-like 3 (EC 3.1.1.-)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07859 Abhydrolase_3 115 269 alpha/beta hydrolase fold Domain
PF07859 Abhydrolase_3 286 381 alpha/beta hydrolase fold Domain
Sequence
Sequence length 407
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Familial cancer of breast Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OBESITY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1 Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma Intraductal Noninfiltrating Intraductal noninfiltrating carcinoma Pubtator 40629431 Associate
★☆☆☆☆
Found in Text Mining only
Sarcoidosis Sarcoidosis Pubtator 31921204 Associate
★☆☆☆☆
Found in Text Mining only