C2CD4C (C2 calcium dependent domain containing 4C)

Gene

• Entrez ID: 126567
• Gene name: C2 calcium dependent domain containing 4C
• Gene symbol: C2CD4C
• Synonyms (NCBI Gene): FAM148C, KIAA1957, NLF3
• Chromosome: 19
• Chromosome location: 19p13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT845424	hsa-miR-137	CLIP-seq
MIRT845425	hsa-miR-150	CLIP-seq
MIRT845426	hsa-miR-25	CLIP-seq
MIRT845427	hsa-miR-2861	CLIP-seq
MIRT845428	hsa-miR-3120-3p	CLIP-seq
MIRT845429	hsa-miR-3192	CLIP-seq
MIRT845430	hsa-miR-32	CLIP-seq
MIRT845431	hsa-miR-320e	CLIP-seq
MIRT845432	hsa-miR-363	CLIP-seq
MIRT845433	hsa-miR-3650	CLIP-seq
MIRT845434	hsa-miR-367	CLIP-seq
MIRT845435	hsa-miR-3689a-3p	CLIP-seq
MIRT845436	hsa-miR-3689c	CLIP-seq
MIRT845437	hsa-miR-3918	CLIP-seq
MIRT845438	hsa-miR-4270	CLIP-seq
MIRT845439	hsa-miR-4325	CLIP-seq
MIRT845440	hsa-miR-4441	CLIP-seq
MIRT845441	hsa-miR-4512	CLIP-seq
MIRT845442	hsa-miR-4646-5p	CLIP-seq
MIRT845443	hsa-miR-4690-3p	CLIP-seq
MIRT845444	hsa-miR-4711-5p	CLIP-seq
MIRT845445	hsa-miR-4713-5p	CLIP-seq
MIRT845446	hsa-miR-4728-5p	CLIP-seq
MIRT845447	hsa-miR-4731-5p	CLIP-seq
MIRT845448	hsa-miR-4747-5p	CLIP-seq
MIRT845449	hsa-miR-4749-3p	CLIP-seq
MIRT845450	hsa-miR-4773	CLIP-seq
MIRT845451	hsa-miR-532-3p	CLIP-seq
MIRT845452	hsa-miR-548v	CLIP-seq
MIRT845453	hsa-miR-615-5p	CLIP-seq
MIRT845454	hsa-miR-644	CLIP-seq
MIRT845455	hsa-miR-661	CLIP-seq
MIRT845456	hsa-miR-663b	CLIP-seq
MIRT845457	hsa-miR-92a	CLIP-seq
MIRT845458	hsa-miR-92b	CLIP-seq
MIRT1950774	hsa-miR-1324	CLIP-seq
MIRT1950775	hsa-miR-3117-5p	CLIP-seq
MIRT2188632	hsa-miR-1226	CLIP-seq
MIRT2188633	hsa-miR-4530	CLIP-seq
MIRT2188634	hsa-miR-634	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	IEA

Other IDs

• MIM: 610336
• HGNC: 29417
• e!Ensembl: ENSG00000183186

Protein

• UniProt ID: Q8TF44
• Protein name: C2 calcium-dependent domain-containing protein 4C (Nuclear-localized factor 3) (Protein FAM148C)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00168	C2	320 → 419	C2 domain	Domain

• Sequence:

  MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
  AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
  LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
  AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
  GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
  VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
  TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF
  L

• Sequence length: 421

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SAPHO SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations