Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	126382
Gene name	Nuclear receptor 2C2 associated protein
Gene symbol	NR2C2AP
Synonyms (NCBI Gene)	TRA16
Chromosome	19
Chromosome location	19p13.11

132

Show/Hide all (132)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020167	hsa-miR-130b-3p	Sequencing	20371350
MIRT024142	hsa-miR-221-3p	Sequencing	20371350
MIRT027991	hsa-miR-93-5p	Sequencing	20371350
MIRT028208	hsa-miR-33a-5p	Sequencing	20371350
MIRT1192446	hsa-miR-106a	CLIP-seq
MIRT1192447	hsa-miR-106b	CLIP-seq
MIRT1192448	hsa-miR-1343	CLIP-seq
MIRT1192449	hsa-miR-150	CLIP-seq
MIRT1192450	hsa-miR-17	CLIP-seq
MIRT1192451	hsa-miR-1914	CLIP-seq
MIRT1192452	hsa-miR-20a	CLIP-seq
MIRT1192453	hsa-miR-20b	CLIP-seq
MIRT1192454	hsa-miR-3175	CLIP-seq
MIRT1192455	hsa-miR-342-5p	CLIP-seq
MIRT1192456	hsa-miR-3936	CLIP-seq
MIRT1192457	hsa-miR-4271	CLIP-seq
MIRT1192458	hsa-miR-4278	CLIP-seq
MIRT1192459	hsa-miR-4651	CLIP-seq
MIRT1192460	hsa-miR-4664-5p	CLIP-seq
MIRT1192461	hsa-miR-4713-5p	CLIP-seq
MIRT1192462	hsa-miR-4725-3p	CLIP-seq
MIRT1192463	hsa-miR-519a	CLIP-seq
MIRT1192464	hsa-miR-519b-3p	CLIP-seq
MIRT1192465	hsa-miR-519c-3p	CLIP-seq
MIRT1192466	hsa-miR-519d	CLIP-seq
MIRT1192467	hsa-miR-520d-5p	CLIP-seq
MIRT1192468	hsa-miR-524-5p	CLIP-seq
MIRT1192469	hsa-miR-532-3p	CLIP-seq
MIRT1192470	hsa-miR-548t	CLIP-seq
MIRT1192471	hsa-miR-608	CLIP-seq
MIRT1192472	hsa-miR-657	CLIP-seq
MIRT1192473	hsa-miR-93	CLIP-seq
MIRT2055906	hsa-miR-1224-3p	CLIP-seq
MIRT2055907	hsa-miR-1324	CLIP-seq
MIRT2055908	hsa-miR-1912	CLIP-seq
MIRT2055909	hsa-miR-2110	CLIP-seq
MIRT2055910	hsa-miR-2276	CLIP-seq
MIRT2055911	hsa-miR-2355-3p	CLIP-seq
MIRT1192454	hsa-miR-3175	CLIP-seq
MIRT2055912	hsa-miR-3194-3p	CLIP-seq
MIRT2055913	hsa-miR-339-5p	CLIP-seq
MIRT2055914	hsa-miR-3607-3p	CLIP-seq
MIRT2055915	hsa-miR-3665	CLIP-seq
MIRT2055916	hsa-miR-3686	CLIP-seq
MIRT1192456	hsa-miR-3936	CLIP-seq
MIRT1192457	hsa-miR-4271	CLIP-seq
MIRT2055917	hsa-miR-4487	CLIP-seq
MIRT2055918	hsa-miR-4646-3p	CLIP-seq
MIRT2055919	hsa-miR-4652-5p	CLIP-seq
MIRT2055920	hsa-miR-4667-5p	CLIP-seq
MIRT2055921	hsa-miR-4700-5p	CLIP-seq
MIRT2055922	hsa-miR-4708-3p	CLIP-seq
MIRT1192462	hsa-miR-4725-3p	CLIP-seq
MIRT2055923	hsa-miR-4731-5p	CLIP-seq
MIRT2055924	hsa-miR-4763-5p	CLIP-seq
MIRT2055925	hsa-miR-4772-3p	CLIP-seq
MIRT2055926	hsa-miR-516a-3p	CLIP-seq
MIRT1192470	hsa-miR-548t	CLIP-seq
MIRT2055927	hsa-miR-593	CLIP-seq
MIRT1192472	hsa-miR-657	CLIP-seq
MIRT1192448	hsa-miR-1343	CLIP-seq
MIRT1192457	hsa-miR-4271	CLIP-seq
MIRT1192458	hsa-miR-4278	CLIP-seq
MIRT1192462	hsa-miR-4725-3p	CLIP-seq
MIRT2455411	hsa-miR-1237	CLIP-seq
MIRT2455412	hsa-miR-1299	CLIP-seq
MIRT2455413	hsa-miR-298	CLIP-seq
MIRT2455414	hsa-miR-3125	CLIP-seq
MIRT2455415	hsa-miR-3144-5p	CLIP-seq
MIRT2455416	hsa-miR-3182	CLIP-seq
MIRT2455417	hsa-miR-3689a-3p	CLIP-seq
MIRT2455418	hsa-miR-3689c	CLIP-seq
MIRT2455419	hsa-miR-3714	CLIP-seq
MIRT2455420	hsa-miR-378	CLIP-seq
MIRT2455421	hsa-miR-378b	CLIP-seq
MIRT2455422	hsa-miR-378c	CLIP-seq
MIRT2455423	hsa-miR-378d	CLIP-seq
MIRT2455424	hsa-miR-378e	CLIP-seq
MIRT2455425	hsa-miR-378f	CLIP-seq
MIRT2455426	hsa-miR-378h	CLIP-seq
MIRT2455427	hsa-miR-378i	CLIP-seq
MIRT2455428	hsa-miR-3914	CLIP-seq
MIRT2455429	hsa-miR-3916	CLIP-seq
MIRT2455430	hsa-miR-3928	CLIP-seq
MIRT2455431	hsa-miR-3944-5p	CLIP-seq
MIRT2455432	hsa-miR-422a	CLIP-seq
MIRT2455433	hsa-miR-4520a-3p	CLIP-seq
MIRT2455434	hsa-miR-4638-3p	CLIP-seq
MIRT2455435	hsa-miR-4728-5p	CLIP-seq
MIRT2455436	hsa-miR-4782-5p	CLIP-seq
MIRT2455437	hsa-miR-516b	CLIP-seq
MIRT2455438	hsa-miR-541	CLIP-seq
MIRT2455439	hsa-miR-548an	CLIP-seq
MIRT2455440	hsa-miR-552	CLIP-seq
MIRT2455441	hsa-miR-617	CLIP-seq
MIRT2455442	hsa-miR-654-5p	CLIP-seq
MIRT2455412	hsa-miR-1299	CLIP-seq
MIRT2455419	hsa-miR-3714	CLIP-seq
MIRT2455420	hsa-miR-378	CLIP-seq
MIRT2455421	hsa-miR-378b	CLIP-seq
MIRT2455422	hsa-miR-378c	CLIP-seq
MIRT2455423	hsa-miR-378d	CLIP-seq
MIRT2455424	hsa-miR-378e	CLIP-seq
MIRT2455425	hsa-miR-378f	CLIP-seq
MIRT2455426	hsa-miR-378h	CLIP-seq
MIRT2455427	hsa-miR-378i	CLIP-seq
MIRT2455432	hsa-miR-422a	CLIP-seq
MIRT2455433	hsa-miR-4520a-3p	CLIP-seq
MIRT2455434	hsa-miR-4638-3p	CLIP-seq
MIRT2455436	hsa-miR-4782-5p	CLIP-seq
MIRT2455437	hsa-miR-516b	CLIP-seq
MIRT2455438	hsa-miR-541	CLIP-seq
MIRT2455440	hsa-miR-552	CLIP-seq
MIRT2455442	hsa-miR-654-5p	CLIP-seq
MIRT2455412	hsa-miR-1299	CLIP-seq
MIRT2455419	hsa-miR-3714	CLIP-seq
MIRT2455420	hsa-miR-378	CLIP-seq
MIRT2455421	hsa-miR-378b	CLIP-seq
MIRT2455422	hsa-miR-378c	CLIP-seq
MIRT2455423	hsa-miR-378d	CLIP-seq
MIRT2455424	hsa-miR-378e	CLIP-seq
MIRT2455425	hsa-miR-378f	CLIP-seq
MIRT2455426	hsa-miR-378h	CLIP-seq
MIRT2455427	hsa-miR-378i	CLIP-seq
MIRT2455432	hsa-miR-422a	CLIP-seq
MIRT2455433	hsa-miR-4520a-3p	CLIP-seq
MIRT2455434	hsa-miR-4638-3p	CLIP-seq
MIRT2455436	hsa-miR-4782-5p	CLIP-seq
MIRT2455437	hsa-miR-516b	CLIP-seq
MIRT2455439	hsa-miR-548an	CLIP-seq
MIRT2455440	hsa-miR-552	CLIP-seq
MIRT2455441	hsa-miR-617	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	12486131, 25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS

MIM	HGNC	e!Ensembl
608719	30763	ENSG00000184162

Q86WQ0

Protein name

Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein)

Protein function

May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas. {ECO:0000269|PubMed:12486131}.

Sequence

MTHSLVCPETVSRVSSVLNRNTRQFGKKHLFDQDEETCWNSDQGPSQWVTLEFPQLIRVS
QLQIQFQGGFSSRRGCLEGSQGTQALHKIVDFYPEDNNSLQTFPIPAAEVDRLKVTFEDA
TDFFGRVVIYHLRVLGEKV

Sequence length

139

Interactions

View interactions

	Reactome
			Nuclear Receptor transcription pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Neoplasms	Neoplasms	BEFREE	23129017	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	23129017	★★★★★ ★☆☆☆☆ Found in Text Mining only

NR2C2AP (nuclear receptor 2C2 associated protein)