ZNF787 (zinc finger protein 787)

Gene

• Entrez ID: 126208
• Gene name: Zinc finger protein 787
• Gene symbol: ZNF787
• Synonyms (NCBI Gene): TIP20
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1539911	hsa-miR-1181	CLIP-seq
MIRT1539912	hsa-miR-296-5p	CLIP-seq
MIRT1539913	hsa-miR-3184	CLIP-seq
MIRT1539914	hsa-miR-431	CLIP-seq
MIRT1539915	hsa-miR-4749-3p	CLIP-seq
MIRT1539912	hsa-miR-296-5p	CLIP-seq
MIRT1539915	hsa-miR-4749-3p	CLIP-seq
MIRT2163132	hsa-miR-1302	CLIP-seq
MIRT2163133	hsa-miR-1825	CLIP-seq
MIRT1539912	hsa-miR-296-5p	CLIP-seq
MIRT1539913	hsa-miR-3184	CLIP-seq
MIRT2163134	hsa-miR-3667-3p	CLIP-seq
MIRT2163135	hsa-miR-4298	CLIP-seq
MIRT2163136	hsa-miR-4434	CLIP-seq
MIRT2163137	hsa-miR-4516	CLIP-seq
MIRT2163138	hsa-miR-4650-5p	CLIP-seq
MIRT2163139	hsa-miR-4691-5p	CLIP-seq
MIRT2163140	hsa-miR-4707-3p	CLIP-seq
MIRT1539915	hsa-miR-4749-3p	CLIP-seq
MIRT2163141	hsa-miR-661	CLIP-seq
MIRT2163142	hsa-miR-887	CLIP-seq
MIRT1539912	hsa-miR-296-5p	CLIP-seq
MIRT2382218	hsa-miR-3065-3p	CLIP-seq
MIRT2163140	hsa-miR-4707-3p	CLIP-seq
MIRT1539915	hsa-miR-4749-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6DD87
• Protein name: Zinc finger protein 787 (TTF-I-interacting peptide 20)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	66 → 88	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	95 → 116	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	122 → 144	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	150 → 172	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	178 → 200	Zinc finger, C2H2 type	Domain
  PF13912	zf-C2H2_6	316 → 340		Domain

• Sequence:

  MELREEAWSPGPLDSEDQQMASHENPVDILIMDDDDVPSWPPTKLSPPQSAPPAGPPPRP
  RPPAPYICNECGKSFSHWSKLTRHQRTHTGERPNACADCGKTFSQSSHLVQHRRIHTGEK
  PYACLECGKRFSWSSNLMQHQRIHTGEKPYTCPDCGRSFTQSKSLAKHRRSHSGLKPFVC
  PRCGRGFSQPKSLARHLRLHPELSGPGVAAKVLAASVRRAKGPEEAVAADGEIAIPVGDG
  EGIIVVGAPGEGAAAAAAMAGAGAKAAGPRSRRAPAPKPYVCLECGKGFGHGAGLLAHQR
  AQHGDGLGAAGGEEPAHICVECGEGFVQGAALRRHKKIHAVGAPSVCSSCGQSYYRAGGE
  EEDDDDEAAGGRCPECRGGEGR

• Sequence length: 382

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ASPHYXIA NEONATORUM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IGA GLOMERULONEPHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOBIUS SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Oromandibular-limb hypogenesis spectrum	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPERMATOCELE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only