Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	124565
Gene name	Solute carrier family 38 member 10
Gene symbol	SLC38A10
Synonyms (NCBI Gene)	PP1744SNAT10
Chromosome	17
Chromosome location	17q25.3

Show/Hide all (56)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028988	hsa-miR-26b-5p	Microarray	19088304
MIRT1362249	hsa-miR-140-3p	CLIP-seq
MIRT1362250	hsa-miR-2355-5p	CLIP-seq
MIRT1362251	hsa-miR-3150a-3p	CLIP-seq
MIRT1362252	hsa-miR-3175	CLIP-seq
MIRT1362253	hsa-miR-4279	CLIP-seq
MIRT1362254	hsa-miR-4292	CLIP-seq
MIRT1362255	hsa-miR-4293	CLIP-seq
MIRT1362256	hsa-miR-4318	CLIP-seq
MIRT1362257	hsa-miR-4648	CLIP-seq
MIRT1362258	hsa-miR-4654	CLIP-seq
MIRT1362259	hsa-miR-4660	CLIP-seq
MIRT1362260	hsa-miR-4667-5p	CLIP-seq
MIRT1362261	hsa-miR-4700-5p	CLIP-seq
MIRT1362262	hsa-miR-4747-5p	CLIP-seq
MIRT1362263	hsa-miR-4769-5p	CLIP-seq
MIRT1362264	hsa-miR-574-5p	CLIP-seq
MIRT1362265	hsa-miR-646	CLIP-seq
MIRT1362266	hsa-miR-658	CLIP-seq
MIRT1362267	hsa-miR-939	CLIP-seq
MIRT2107323	hsa-miR-1324	CLIP-seq
MIRT1362251	hsa-miR-3150a-3p	CLIP-seq
MIRT1362252	hsa-miR-3175	CLIP-seq
MIRT2107324	hsa-miR-3616-3p	CLIP-seq
MIRT1362254	hsa-miR-4292	CLIP-seq
MIRT2107325	hsa-miR-4512	CLIP-seq
MIRT1362260	hsa-miR-4667-5p	CLIP-seq
MIRT1362261	hsa-miR-4700-5p	CLIP-seq
MIRT1362267	hsa-miR-939	CLIP-seq
MIRT2625873	hsa-miR-1226	CLIP-seq
MIRT2107323	hsa-miR-1324	CLIP-seq
MIRT1362250	hsa-miR-2355-5p	CLIP-seq
MIRT2625874	hsa-miR-3192	CLIP-seq
MIRT2625875	hsa-miR-3614-5p	CLIP-seq
MIRT2107324	hsa-miR-3616-3p	CLIP-seq
MIRT2625876	hsa-miR-4267	CLIP-seq
MIRT1362255	hsa-miR-4293	CLIP-seq
MIRT2107325	hsa-miR-4512	CLIP-seq
MIRT1362259	hsa-miR-4660	CLIP-seq
MIRT2625877	hsa-miR-4710	CLIP-seq
MIRT2625878	hsa-miR-4721	CLIP-seq
MIRT2625879	hsa-miR-4792	CLIP-seq
MIRT1362265	hsa-miR-646	CLIP-seq
MIRT1362266	hsa-miR-658	CLIP-seq
MIRT2625880	hsa-miR-661	CLIP-seq
MIRT2625881	hsa-miR-767-5p	CLIP-seq
MIRT2625873	hsa-miR-1226	CLIP-seq
MIRT1362250	hsa-miR-2355-5p	CLIP-seq
MIRT2625874	hsa-miR-3192	CLIP-seq
MIRT2625876	hsa-miR-4267	CLIP-seq
MIRT1362255	hsa-miR-4293	CLIP-seq
MIRT1362259	hsa-miR-4660	CLIP-seq
MIRT1362265	hsa-miR-646	CLIP-seq
MIRT1362266	hsa-miR-658	CLIP-seq
MIRT2625880	hsa-miR-661	CLIP-seq
MIRT2625881	hsa-miR-767-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0003333	Process	Amino acid transmembrane transport	IBA
GO:0005794	Component	Golgi apparatus	IDA
GO:0006865	Process	Amino acid transport	IEA
GO:0015179	Function	L-amino acid transmembrane transporter activity	IBA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0060348	Process	Bone development	IEA
GO:1902475	Process	L-alpha-amino acid transmembrane transport	IEA

MIM	HGNC	e!Ensembl
616525	28237	ENSG00000157637

Q9HBR0

Protein name

Solute carrier family 38 member 10 (Amino acid transporter SLC38A10)

Protein function

Facilitates bidirectional transport of amino acids. May act as a glutamate sensor that regulates glutamate-glutamine cycle and mTOR signaling in the brain. The transport mechanism remains to be elucidated.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01490	Aa_trans	4 → 398	Transmembrane amino acid transporter protein	Family

Sequence

MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKS
ASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQV
GGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSG
QWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTF
YVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLL
CEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFI
CPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGL
MKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQL
DRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAP
PLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGD
RGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPA
PGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQE
KLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLP
LDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDA
APRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVA
ATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPE
LRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPEL
GLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDV
QVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES

Sequence length

1119

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SLC38A10-related disorder	Likely benign; Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

SLC38A10 (solute carrier family 38 member 10)