Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	124245
Gene name	Zinc finger CCCH-type containing 18
Gene symbol	ZC3H18
Synonyms (NCBI Gene)	NHN1
Chromosome	16
Chromosome location	16q24.2

143

Show/Hide all (143)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052361	hsa-let-7a-5p	CLASH	23622248
MIRT052361	hsa-let-7a-5p	CLASH	23622248
MIRT051354	hsa-let-7f-5p	CLASH	23622248
MIRT050795	hsa-miR-17-5p	CLASH	23622248
MIRT050651	hsa-miR-18a-5p	CLASH	23622248
MIRT049858	hsa-miR-31-5p	CLASH	23622248
MIRT049259	hsa-miR-92a-3p	CLASH	23622248
MIRT047551	hsa-miR-10a-5p	CLASH	23622248
MIRT047405	hsa-miR-10b-5p	CLASH	23622248
MIRT047038	hsa-miR-183-5p	CLASH	23622248
MIRT046984	hsa-miR-218-5p	CLASH	23622248
MIRT044256	hsa-miR-106b-5p	CLASH	23622248
MIRT042403	hsa-miR-18b-5p	CLASH	23622248
MIRT041631	hsa-miR-484	CLASH	23622248
MIRT038721	hsa-miR-93-3p	CLASH	23622248
MIRT038709	hsa-miR-29b-2-5p	CLASH	23622248
MIRT035777	hsa-miR-1914-3p	CLASH	23622248
MIRT1505816	hsa-miR-1200	CLIP-seq
MIRT1505817	hsa-miR-1321	CLIP-seq
MIRT1505818	hsa-miR-133a	CLIP-seq
MIRT1505819	hsa-miR-133b	CLIP-seq
MIRT1505820	hsa-miR-146a	CLIP-seq
MIRT1505821	hsa-miR-146b-5p	CLIP-seq
MIRT1505822	hsa-miR-147	CLIP-seq
MIRT1505823	hsa-miR-1914	CLIP-seq
MIRT1505824	hsa-miR-2054	CLIP-seq
MIRT1505825	hsa-miR-3074-5p	CLIP-seq
MIRT1505826	hsa-miR-3150a-3p	CLIP-seq
MIRT1505827	hsa-miR-3163	CLIP-seq
MIRT1505828	hsa-miR-3175	CLIP-seq
MIRT1505829	hsa-miR-3180-5p	CLIP-seq
MIRT1505830	hsa-miR-3194-3p	CLIP-seq
MIRT1505831	hsa-miR-326	CLIP-seq
MIRT1505832	hsa-miR-330-5p	CLIP-seq
MIRT1505833	hsa-miR-3686	CLIP-seq
MIRT1505834	hsa-miR-3911	CLIP-seq
MIRT1505835	hsa-miR-3924	CLIP-seq
MIRT1505836	hsa-miR-4251	CLIP-seq
MIRT1505837	hsa-miR-4267	CLIP-seq
MIRT1505838	hsa-miR-4283	CLIP-seq
MIRT1505839	hsa-miR-4419a	CLIP-seq
MIRT1505840	hsa-miR-4474-3p	CLIP-seq
MIRT1505841	hsa-miR-4489	CLIP-seq
MIRT1505842	hsa-miR-4505	CLIP-seq
MIRT1505843	hsa-miR-4510	CLIP-seq
MIRT1505844	hsa-miR-4652-3p	CLIP-seq
MIRT1505845	hsa-miR-4666-5p	CLIP-seq
MIRT1505846	hsa-miR-4667-5p	CLIP-seq
MIRT1505847	hsa-miR-4700-5p	CLIP-seq
MIRT1505848	hsa-miR-4728-5p	CLIP-seq
MIRT1505849	hsa-miR-4731-5p	CLIP-seq
MIRT1505850	hsa-miR-4734	CLIP-seq
MIRT1505851	hsa-miR-4739	CLIP-seq
MIRT1505852	hsa-miR-4742-3p	CLIP-seq
MIRT1505853	hsa-miR-4756-5p	CLIP-seq
MIRT1505854	hsa-miR-485-5p	CLIP-seq
MIRT1505855	hsa-miR-539	CLIP-seq
MIRT1505856	hsa-miR-548c-3p	CLIP-seq
MIRT1505857	hsa-miR-568	CLIP-seq
MIRT1505858	hsa-miR-589	CLIP-seq
MIRT1505859	hsa-miR-616	CLIP-seq
MIRT1505860	hsa-miR-637	CLIP-seq
MIRT1505861	hsa-miR-644	CLIP-seq
MIRT1505862	hsa-miR-767-3p	CLIP-seq
MIRT1505863	hsa-miR-939	CLIP-seq
MIRT2152270	hsa-miR-1254	CLIP-seq
MIRT1505817	hsa-miR-1321	CLIP-seq
MIRT1505818	hsa-miR-133a	CLIP-seq
MIRT1505819	hsa-miR-133b	CLIP-seq
MIRT1505820	hsa-miR-146a	CLIP-seq
MIRT1505821	hsa-miR-146b-5p	CLIP-seq
MIRT2152271	hsa-miR-1539	CLIP-seq
MIRT1505823	hsa-miR-1914	CLIP-seq
MIRT1505824	hsa-miR-2054	CLIP-seq
MIRT2152272	hsa-miR-3064-5p	CLIP-seq
MIRT2152273	hsa-miR-3116	CLIP-seq
MIRT2152274	hsa-miR-3120-5p	CLIP-seq
MIRT1505826	hsa-miR-3150a-3p	CLIP-seq
MIRT1505828	hsa-miR-3175	CLIP-seq
MIRT1505829	hsa-miR-3180-5p	CLIP-seq
MIRT2152275	hsa-miR-3193	CLIP-seq
MIRT1505830	hsa-miR-3194-3p	CLIP-seq
MIRT1505831	hsa-miR-326	CLIP-seq
MIRT1505832	hsa-miR-330-5p	CLIP-seq
MIRT2152276	hsa-miR-3664-3p	CLIP-seq
MIRT2152277	hsa-miR-3690	CLIP-seq
MIRT2152278	hsa-miR-383	CLIP-seq
MIRT1505836	hsa-miR-4251	CLIP-seq
MIRT1505837	hsa-miR-4267	CLIP-seq
MIRT1505839	hsa-miR-4419a	CLIP-seq
MIRT2152279	hsa-miR-4433	CLIP-seq
MIRT2152280	hsa-miR-4454	CLIP-seq
MIRT2152281	hsa-miR-4459	CLIP-seq
MIRT1505842	hsa-miR-4505	CLIP-seq
MIRT1505843	hsa-miR-4510	CLIP-seq
MIRT1505845	hsa-miR-4666-5p	CLIP-seq
MIRT1505846	hsa-miR-4667-5p	CLIP-seq
MIRT1505847	hsa-miR-4700-5p	CLIP-seq
MIRT2152282	hsa-miR-4711-3p	CLIP-seq
MIRT1505848	hsa-miR-4728-5p	CLIP-seq
MIRT1505850	hsa-miR-4734	CLIP-seq
MIRT1505851	hsa-miR-4739	CLIP-seq
MIRT1505853	hsa-miR-4756-5p	CLIP-seq
MIRT2152283	hsa-miR-4762-3p	CLIP-seq
MIRT2152284	hsa-miR-4768-3p	CLIP-seq
MIRT2152285	hsa-miR-4772-5p	CLIP-seq
MIRT2152286	hsa-miR-4779	CLIP-seq
MIRT1505854	hsa-miR-485-5p	CLIP-seq
MIRT1505855	hsa-miR-539	CLIP-seq
MIRT1505858	hsa-miR-589	CLIP-seq
MIRT2152287	hsa-miR-604	CLIP-seq
MIRT1505859	hsa-miR-616	CLIP-seq
MIRT2152288	hsa-miR-626	CLIP-seq
MIRT1505860	hsa-miR-637	CLIP-seq
MIRT2152289	hsa-miR-647	CLIP-seq
MIRT2152290	hsa-miR-661	CLIP-seq
MIRT2152291	hsa-miR-711	CLIP-seq
MIRT1505862	hsa-miR-767-3p	CLIP-seq
MIRT1505863	hsa-miR-939	CLIP-seq
MIRT2152270	hsa-miR-1254	CLIP-seq
MIRT2665567	hsa-miR-140-5p	CLIP-seq
MIRT2665568	hsa-miR-1468	CLIP-seq
MIRT2665569	hsa-miR-1912	CLIP-seq
MIRT2152272	hsa-miR-3064-5p	CLIP-seq
MIRT2152273	hsa-miR-3116	CLIP-seq
MIRT2152276	hsa-miR-3664-3p	CLIP-seq
MIRT2152277	hsa-miR-3690	CLIP-seq
MIRT1505838	hsa-miR-4283	CLIP-seq
MIRT1505839	hsa-miR-4419a	CLIP-seq
MIRT2152279	hsa-miR-4433	CLIP-seq
MIRT2152281	hsa-miR-4459	CLIP-seq
MIRT2665570	hsa-miR-4487	CLIP-seq
MIRT1505841	hsa-miR-4489	CLIP-seq
MIRT1505843	hsa-miR-4510	CLIP-seq
MIRT2665571	hsa-miR-4650-5p	CLIP-seq
MIRT2665572	hsa-miR-4715-3p	CLIP-seq
MIRT1505849	hsa-miR-4731-5p	CLIP-seq
MIRT2152284	hsa-miR-4768-3p	CLIP-seq
MIRT2152286	hsa-miR-4779	CLIP-seq
MIRT2152287	hsa-miR-604	CLIP-seq
MIRT2152289	hsa-miR-647	CLIP-seq
MIRT2152290	hsa-miR-661	CLIP-seq
MIRT2152291	hsa-miR-711	CLIP-seq

Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	21044950, 23793891, 27871484, 32353859, 33060197, 36217030
GO:0005634	Component	Nucleus	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	28297668
GO:0032991	Component	Protein-containing complex	IDA	23793891
GO:0046872	Function	Metal ion binding	IEA
GO:0050779	Process	RNA destabilization	IMP	28297668
GO:0140262	Function	MRNA cap binding complex binding	IDA	28297668
GO:1990904	Component	Ribonucleoprotein complex	IDA	28297668

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q86VM9

Protein name

Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF18044	zf-CCCH_4	222 → 243	CCCH-type zinc finger	Domain

Sequence

MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ
EEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT
RELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL
EAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRF
IHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESA
WERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVR
DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERE
RERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK
GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR
RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR
SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT
KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS
SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK
SAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR
QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS
KVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA

Sequence length

953

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	31604914		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	22371884	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	31604914		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neutropenia Severe Congenital Autosomal Recessive 3	Severe congenital neutropenia	Pubtator	22371884	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	31604914		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	31604914	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZC3H18 (zinc finger CCCH-type containing 18)