Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Other IDs Protein Associated diseases
Entrez ID	121006
Gene name	Family with sequence similarity 186 member A
Gene symbol	FAM186A
Synonyms (NCBI Gene)	-
Chromosome	12
Chromosome location	12q13.12

Show/Hide all (54)

miRTarBase ID	miRNA	Experiments	Reference
MIRT629229	hsa-miR-4445-3p	HITS-CLIP	23824327
MIRT629228	hsa-miR-548al	HITS-CLIP	23824327
MIRT629227	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629224	hsa-miR-92b-5p	HITS-CLIP	23824327
MIRT629223	hsa-miR-7977	HITS-CLIP	23824327
MIRT629222	hsa-miR-1302	HITS-CLIP	23824327
MIRT629221	hsa-miR-4298	HITS-CLIP	23824327
MIRT629220	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629219	hsa-miR-3122	HITS-CLIP	23824327
MIRT629218	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629217	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629216	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT629230	hsa-miR-3714	HITS-CLIP	23824327
MIRT629229	hsa-miR-4445-3p	HITS-CLIP	23824327
MIRT629228	hsa-miR-548al	HITS-CLIP	23824327
MIRT629227	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629226	hsa-miR-4708-3p	HITS-CLIP	23824327
MIRT629225	hsa-miR-6809-5p	HITS-CLIP	23824327
MIRT629224	hsa-miR-92b-5p	HITS-CLIP	23824327
MIRT629223	hsa-miR-7977	HITS-CLIP	23824327
MIRT629222	hsa-miR-1302	HITS-CLIP	23824327
MIRT629221	hsa-miR-4298	HITS-CLIP	23824327
MIRT629220	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629219	hsa-miR-3122	HITS-CLIP	23824327
MIRT629218	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629217	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629216	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT629229	hsa-miR-4445-3p	HITS-CLIP	23824327
MIRT629228	hsa-miR-548al	HITS-CLIP	23824327
MIRT629227	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629224	hsa-miR-92b-5p	HITS-CLIP	23824327
MIRT629223	hsa-miR-7977	HITS-CLIP	23824327
MIRT629222	hsa-miR-1302	HITS-CLIP	23824327
MIRT629221	hsa-miR-4298	HITS-CLIP	23824327
MIRT629220	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629219	hsa-miR-3122	HITS-CLIP	23824327
MIRT629218	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629217	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629216	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT629230	hsa-miR-3714	HITS-CLIP	23824327
MIRT629229	hsa-miR-4445-3p	HITS-CLIP	23824327
MIRT629228	hsa-miR-548al	HITS-CLIP	23824327
MIRT629227	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629226	hsa-miR-4708-3p	HITS-CLIP	23824327
MIRT629225	hsa-miR-6809-5p	HITS-CLIP	23824327
MIRT629224	hsa-miR-92b-5p	HITS-CLIP	23824327
MIRT629223	hsa-miR-7977	HITS-CLIP	23824327
MIRT629222	hsa-miR-1302	HITS-CLIP	23824327
MIRT629221	hsa-miR-4298	HITS-CLIP	23824327
MIRT629220	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629219	hsa-miR-3122	HITS-CLIP	23824327
MIRT629218	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629217	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629216	hsa-miR-6513-5p	HITS-CLIP	23824327

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

A6NE01

Protein name

Protein FAM186A

Family and domains

Sequence

MFFKMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLH
RAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTI
EIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFS
TSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVSEIQGM
LQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKE
LSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQS
SRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL
RQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNK
SGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTS
MMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEP
QKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESP
DGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEE
YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS
YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLK
QQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQ
AEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHR
RREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDV
QRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQA
QEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQT
QVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA
QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV
QELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQA
QALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQA
QELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQA
QALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQA
QALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQA
QELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQA
QALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQA
QEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSL
ASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQ
TLVYGGQSTSAQFPAPQAPPSPGQLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQ
PLVPEASSIPGDLLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRAS
SLWIPPTSRHPPTLWPSPAPGKPQKSWSPSVAKKRLAIISSLKSKSVLIHPSAPDFKVAQ
VPFTTKKFQMSEVSDTSEETQILRDTFAIESFRTFQSHFTKYRTPVYQTPYTDERALLTL
MKPTTSPSSLTTLLRTSQISPLEWYQKSRFPPIDKPWILSSVSDTKKPKVMVPPSSPQEL
EEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLFRKYIA
YRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSLGQKRN
QCLKKMIHVFNQLKKIHELNLSQPIPLIIEEKQIPASTTFVQKPFLKLLMEEDRTSDICK
KFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLLQLEVQSTFRKSLA
SLQSRVKKIPK

Sequence length

2351

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
beta Thalassemia	Beta thalassemia	Pubtator	36939018	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	26553438		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	26553438	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

FAM186A (family with sequence similarity 186 member A)