CLCN6 (chloride voltage-gated channel 6)

Gene

• Entrez ID: 1185
• Gene name: Chloride voltage-gated channel 6
• Gene symbol: CLCN6
• Synonyms (NCBI Gene): CLC-6, CONRIBA
• Chromosome: 1
• Chromosome location: 1p36.22
• Summary: This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton a

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017686	hsa-miR-335-5p	Microarray	18185580
MIRT046450	hsa-miR-15b-5p	CLASH	23622248
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22291592
MIRT448912	hsa-miR-3167	PAR-CLIP	22291592
MIRT448911	hsa-miR-378j	PAR-CLIP	22291592
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22291592
MIRT448909	hsa-miR-4635	PAR-CLIP	22291592
MIRT448908	hsa-miR-3135b	PAR-CLIP	22291592
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22291592
MIRT448906	hsa-miR-1290	PAR-CLIP	22291592
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22291592
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22291592
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT448901	hsa-miR-578	PAR-CLIP	22291592
MIRT495867	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495866	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495865	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT495864	hsa-miR-6865-3p	PAR-CLIP	22291592
MIRT495863	hsa-miR-877-3p	PAR-CLIP	22291592
MIRT495862	hsa-miR-372-5p	PAR-CLIP	22291592
MIRT495861	hsa-miR-1236-3p	PAR-CLIP	22291592
MIRT495860	hsa-miR-4529-5p	PAR-CLIP	22291592
MIRT495859	hsa-miR-5704	PAR-CLIP	22291592
MIRT495858	hsa-miR-3671	PAR-CLIP	22291592
MIRT495857	hsa-miR-670-3p	PAR-CLIP	22291592
MIRT495867	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495866	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495865	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT495864	hsa-miR-6865-3p	PAR-CLIP	22291592
MIRT495863	hsa-miR-877-3p	PAR-CLIP	22291592
MIRT495862	hsa-miR-372-5p	PAR-CLIP	22291592
MIRT495861	hsa-miR-1236-3p	PAR-CLIP	22291592
MIRT495860	hsa-miR-4529-5p	PAR-CLIP	22291592
MIRT495859	hsa-miR-5704	PAR-CLIP	22291592
MIRT495858	hsa-miR-3671	PAR-CLIP	22291592
MIRT495857	hsa-miR-670-3p	PAR-CLIP	22291592
MIRT448917	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT448916	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448915	hsa-miR-1302	PAR-CLIP	22100165
MIRT448914	hsa-miR-4298	PAR-CLIP	22100165
MIRT450892	hsa-miR-3122	PAR-CLIP	22100165
MIRT450891	hsa-miR-3913-5p	PAR-CLIP	22100165
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22100165
MIRT448912	hsa-miR-3167	PAR-CLIP	22100165
MIRT448911	hsa-miR-378j	PAR-CLIP	22100165
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22100165
MIRT448909	hsa-miR-4635	PAR-CLIP	22100165
MIRT448908	hsa-miR-3135b	PAR-CLIP	22100165
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22100165
MIRT448906	hsa-miR-1290	PAR-CLIP	22100165
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT448901	hsa-miR-578	PAR-CLIP	22100165
MIRT448917	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT448916	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448915	hsa-miR-1302	PAR-CLIP	22100165
MIRT448914	hsa-miR-4298	PAR-CLIP	22100165
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22100165
MIRT448912	hsa-miR-3167	PAR-CLIP	22100165
MIRT448911	hsa-miR-378j	PAR-CLIP	22100165
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22100165
MIRT448909	hsa-miR-4635	PAR-CLIP	22100165
MIRT448908	hsa-miR-3135b	PAR-CLIP	22100165
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22100165
MIRT448906	hsa-miR-1290	PAR-CLIP	22100165
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT448901	hsa-miR-578	PAR-CLIP	22100165
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22291592
MIRT448912	hsa-miR-3167	PAR-CLIP	22291592
MIRT448911	hsa-miR-378j	PAR-CLIP	22291592
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22291592
MIRT448909	hsa-miR-4635	PAR-CLIP	22291592
MIRT448908	hsa-miR-3135b	PAR-CLIP	22291592
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22291592
MIRT448906	hsa-miR-1290	PAR-CLIP	22291592
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22291592
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22291592
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT448901	hsa-miR-578	PAR-CLIP	22291592
MIRT495867	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495866	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495865	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT495864	hsa-miR-6865-3p	PAR-CLIP	22291592
MIRT495863	hsa-miR-877-3p	PAR-CLIP	22291592
MIRT495862	hsa-miR-372-5p	PAR-CLIP	22291592
MIRT495861	hsa-miR-1236-3p	PAR-CLIP	22291592
MIRT495860	hsa-miR-4529-5p	PAR-CLIP	22291592
MIRT495859	hsa-miR-5704	PAR-CLIP	22291592
MIRT495858	hsa-miR-3671	PAR-CLIP	22291592
MIRT495857	hsa-miR-670-3p	PAR-CLIP	22291592
MIRT495867	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495866	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495865	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT495864	hsa-miR-6865-3p	PAR-CLIP	22291592
MIRT495863	hsa-miR-877-3p	PAR-CLIP	22291592
MIRT495862	hsa-miR-372-5p	PAR-CLIP	22291592
MIRT495861	hsa-miR-1236-3p	PAR-CLIP	22291592
MIRT495860	hsa-miR-4529-5p	PAR-CLIP	22291592
MIRT495859	hsa-miR-5704	PAR-CLIP	22291592
MIRT495858	hsa-miR-3671	PAR-CLIP	22291592
MIRT495857	hsa-miR-670-3p	PAR-CLIP	22291592
MIRT448917	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT448916	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448915	hsa-miR-1302	PAR-CLIP	22100165
MIRT448914	hsa-miR-4298	PAR-CLIP	22100165
MIRT450892	hsa-miR-3122	PAR-CLIP	22100165
MIRT450891	hsa-miR-3913-5p	PAR-CLIP	22100165
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22100165
MIRT448912	hsa-miR-3167	PAR-CLIP	22100165
MIRT448911	hsa-miR-378j	PAR-CLIP	22100165
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22100165
MIRT448909	hsa-miR-4635	PAR-CLIP	22100165
MIRT448908	hsa-miR-3135b	PAR-CLIP	22100165
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22100165
MIRT448906	hsa-miR-1290	PAR-CLIP	22100165
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT448901	hsa-miR-578	PAR-CLIP	22100165
MIRT448917	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT448916	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448915	hsa-miR-1302	PAR-CLIP	22100165
MIRT448914	hsa-miR-4298	PAR-CLIP	22100165
MIRT448913	hsa-miR-876-5p	PAR-CLIP	22100165
MIRT448912	hsa-miR-3167	PAR-CLIP	22100165
MIRT448911	hsa-miR-378j	PAR-CLIP	22100165
MIRT448910	hsa-miR-6839-5p	PAR-CLIP	22100165
MIRT448909	hsa-miR-4635	PAR-CLIP	22100165
MIRT448908	hsa-miR-3135b	PAR-CLIP	22100165
MIRT448907	hsa-miR-1287-5p	PAR-CLIP	22100165
MIRT448906	hsa-miR-1290	PAR-CLIP	22100165
MIRT448905	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT448904	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT448903	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT448901	hsa-miR-578	PAR-CLIP	22100165
MIRT894726	hsa-miR-105	CLIP-seq
MIRT894727	hsa-miR-1184	CLIP-seq
MIRT894728	hsa-miR-1205	CLIP-seq
MIRT894729	hsa-miR-1236	CLIP-seq
MIRT894730	hsa-miR-1237	CLIP-seq
MIRT894731	hsa-miR-1248	CLIP-seq
MIRT894732	hsa-miR-1251	CLIP-seq
MIRT894733	hsa-miR-1253	CLIP-seq
MIRT894734	hsa-miR-1254	CLIP-seq
MIRT894735	hsa-miR-1262	CLIP-seq
MIRT894736	hsa-miR-128	CLIP-seq
MIRT894737	hsa-miR-1292	CLIP-seq
MIRT894738	hsa-miR-130a	CLIP-seq
MIRT894739	hsa-miR-130b	CLIP-seq
MIRT894740	hsa-miR-134	CLIP-seq
MIRT894741	hsa-miR-141	CLIP-seq
MIRT894742	hsa-miR-148a	CLIP-seq
MIRT894743	hsa-miR-148b	CLIP-seq
MIRT894744	hsa-miR-149	CLIP-seq
MIRT894745	hsa-miR-152	CLIP-seq
MIRT894746	hsa-miR-15a	CLIP-seq
MIRT894747	hsa-miR-15b	CLIP-seq
MIRT894748	hsa-miR-16	CLIP-seq
MIRT894749	hsa-miR-185	CLIP-seq
MIRT894750	hsa-miR-1909	CLIP-seq
MIRT894751	hsa-miR-1915	CLIP-seq
MIRT894752	hsa-miR-195	CLIP-seq
MIRT894753	hsa-miR-19a	CLIP-seq
MIRT894754	hsa-miR-19b	CLIP-seq
MIRT894755	hsa-miR-200a	CLIP-seq
MIRT894756	hsa-miR-2115	CLIP-seq
MIRT894757	hsa-miR-2117	CLIP-seq
MIRT894758	hsa-miR-223	CLIP-seq
MIRT894759	hsa-miR-24	CLIP-seq
MIRT894760	hsa-miR-27a	CLIP-seq
MIRT894761	hsa-miR-27b	CLIP-seq
MIRT894762	hsa-miR-301a	CLIP-seq
MIRT894763	hsa-miR-301b	CLIP-seq
MIRT894764	hsa-miR-302a	CLIP-seq
MIRT894765	hsa-miR-302b	CLIP-seq
MIRT894766	hsa-miR-302c	CLIP-seq
MIRT894767	hsa-miR-302d	CLIP-seq
MIRT894768	hsa-miR-302e	CLIP-seq
MIRT894769	hsa-miR-3074-5p	CLIP-seq
MIRT894770	hsa-miR-3116	CLIP-seq
MIRT894771	hsa-miR-3118	CLIP-seq
MIRT894772	hsa-miR-3124-3p	CLIP-seq
MIRT894773	hsa-miR-3148	CLIP-seq
MIRT894774	hsa-miR-3158-5p	CLIP-seq
MIRT894775	hsa-miR-3160-5p	CLIP-seq
MIRT894776	hsa-miR-3166	CLIP-seq
MIRT894777	hsa-miR-3173-5p	CLIP-seq
MIRT894778	hsa-miR-3174	CLIP-seq
MIRT894779	hsa-miR-3175	CLIP-seq
MIRT894780	hsa-miR-3179	CLIP-seq
MIRT894781	hsa-miR-3192	CLIP-seq
MIRT894782	hsa-miR-3194-5p	CLIP-seq
MIRT894783	hsa-miR-320a	CLIP-seq
MIRT894784	hsa-miR-320b	CLIP-seq
MIRT894785	hsa-miR-320c	CLIP-seq
MIRT894786	hsa-miR-320d	CLIP-seq
MIRT894787	hsa-miR-3545-5p	CLIP-seq
MIRT894788	hsa-miR-3611	CLIP-seq
MIRT894789	hsa-miR-3653	CLIP-seq
MIRT894790	hsa-miR-3658	CLIP-seq
MIRT894791	hsa-miR-3666	CLIP-seq
MIRT894792	hsa-miR-3675-5p	CLIP-seq
MIRT894793	hsa-miR-372	CLIP-seq
MIRT894794	hsa-miR-373	CLIP-seq
MIRT894795	hsa-miR-3921	CLIP-seq
MIRT894796	hsa-miR-3977	CLIP-seq
MIRT894797	hsa-miR-3978	CLIP-seq
MIRT894798	hsa-miR-424	CLIP-seq
MIRT894799	hsa-miR-4254	CLIP-seq
MIRT894800	hsa-miR-4276	CLIP-seq
MIRT894801	hsa-miR-4283	CLIP-seq
MIRT894802	hsa-miR-4284	CLIP-seq
MIRT894803	hsa-miR-4295	CLIP-seq
MIRT894804	hsa-miR-4303	CLIP-seq
MIRT894805	hsa-miR-4306	CLIP-seq
MIRT894806	hsa-miR-4421	CLIP-seq
MIRT894807	hsa-miR-4429	CLIP-seq
MIRT894808	hsa-miR-4434	CLIP-seq
MIRT894809	hsa-miR-4436b-3p	CLIP-seq
MIRT894810	hsa-miR-4463	CLIP-seq
MIRT894811	hsa-miR-4471	CLIP-seq
MIRT894812	hsa-miR-4480	CLIP-seq
MIRT894813	hsa-miR-4481	CLIP-seq
MIRT894814	hsa-miR-4489	CLIP-seq
MIRT894815	hsa-miR-4496	CLIP-seq
MIRT894816	hsa-miR-4516	CLIP-seq
MIRT894817	hsa-miR-4531	CLIP-seq
MIRT894818	hsa-miR-4534	CLIP-seq
MIRT894819	hsa-miR-454	CLIP-seq
MIRT894820	hsa-miR-4640-5p	CLIP-seq
MIRT894821	hsa-miR-4644	CLIP-seq
MIRT894822	hsa-miR-4646-5p	CLIP-seq
MIRT894823	hsa-miR-4653-5p	CLIP-seq
MIRT894824	hsa-miR-4671-3p	CLIP-seq
MIRT894825	hsa-miR-4682	CLIP-seq
MIRT894826	hsa-miR-4684-5p	CLIP-seq
MIRT894827	hsa-miR-4697-3p	CLIP-seq
MIRT894828	hsa-miR-4701-3p	CLIP-seq
MIRT894829	hsa-miR-4711-5p	CLIP-seq
MIRT894830	hsa-miR-4719	CLIP-seq
MIRT894831	hsa-miR-4726-5p	CLIP-seq
MIRT894832	hsa-miR-4745-5p	CLIP-seq
MIRT894833	hsa-miR-4758-5p	CLIP-seq
MIRT894834	hsa-miR-4762-3p	CLIP-seq
MIRT894835	hsa-miR-4765	CLIP-seq
MIRT894836	hsa-miR-4769-3p	CLIP-seq
MIRT894837	hsa-miR-485-3p	CLIP-seq
MIRT894838	hsa-miR-487a	CLIP-seq
MIRT894839	hsa-miR-495	CLIP-seq
MIRT894840	hsa-miR-497	CLIP-seq
MIRT894841	hsa-miR-516a-3p	CLIP-seq
MIRT894842	hsa-miR-520a-3p	CLIP-seq
MIRT894843	hsa-miR-520b	CLIP-seq
MIRT894844	hsa-miR-520c-3p	CLIP-seq
MIRT894845	hsa-miR-520d-3p	CLIP-seq
MIRT894846	hsa-miR-520e	CLIP-seq
MIRT894847	hsa-miR-520f	CLIP-seq
MIRT894848	hsa-miR-541	CLIP-seq
MIRT894849	hsa-miR-544	CLIP-seq
MIRT894850	hsa-miR-654-5p	CLIP-seq
MIRT894851	hsa-miR-758	CLIP-seq
MIRT894852	hsa-miR-892b	CLIP-seq
MIRT894853	hsa-miR-9	CLIP-seq
MIRT894726	hsa-miR-105	CLIP-seq
MIRT1965371	hsa-miR-1270	CLIP-seq
MIRT1965372	hsa-miR-133a	CLIP-seq
MIRT1965373	hsa-miR-133b	CLIP-seq
MIRT1965374	hsa-miR-143	CLIP-seq
MIRT1965375	hsa-miR-297	CLIP-seq
MIRT1965376	hsa-miR-320e	CLIP-seq
MIRT1965377	hsa-miR-3591-3p	CLIP-seq
MIRT894797	hsa-miR-3978	CLIP-seq
MIRT1965378	hsa-miR-4270	CLIP-seq
MIRT1965379	hsa-miR-4441	CLIP-seq
MIRT1965380	hsa-miR-4683	CLIP-seq
MIRT894829	hsa-miR-4711-5p	CLIP-seq
MIRT894830	hsa-miR-4719	CLIP-seq
MIRT1965381	hsa-miR-4770	CLIP-seq
MIRT894849	hsa-miR-544	CLIP-seq
MIRT1965382	hsa-miR-567	CLIP-seq
MIRT1965383	hsa-miR-620	CLIP-seq
MIRT2201298	hsa-miR-100	CLIP-seq
MIRT894726	hsa-miR-105	CLIP-seq
MIRT2201299	hsa-miR-1178	CLIP-seq
MIRT894728	hsa-miR-1205	CLIP-seq
MIRT2201300	hsa-miR-1228	CLIP-seq
MIRT2201301	hsa-miR-1266	CLIP-seq
MIRT2201302	hsa-miR-1285	CLIP-seq
MIRT894737	hsa-miR-1292	CLIP-seq
MIRT2201303	hsa-miR-140-3p	CLIP-seq
MIRT894742	hsa-miR-148a	CLIP-seq
MIRT894743	hsa-miR-148b	CLIP-seq
MIRT894745	hsa-miR-152	CLIP-seq
MIRT894750	hsa-miR-1909	CLIP-seq
MIRT894751	hsa-miR-1915	CLIP-seq
MIRT2201304	hsa-miR-200b	CLIP-seq
MIRT2201305	hsa-miR-200c	CLIP-seq
MIRT2201306	hsa-miR-217	CLIP-seq
MIRT894758	hsa-miR-223	CLIP-seq
MIRT2201307	hsa-miR-31	CLIP-seq
MIRT2201308	hsa-miR-3126-3p	CLIP-seq
MIRT2201309	hsa-miR-3127-5p	CLIP-seq
MIRT2201310	hsa-miR-3187-5p	CLIP-seq
MIRT2201311	hsa-miR-326	CLIP-seq
MIRT2201312	hsa-miR-330-5p	CLIP-seq
MIRT2201313	hsa-miR-342-3p	CLIP-seq
MIRT2201314	hsa-miR-3659	CLIP-seq
MIRT2201315	hsa-miR-3675-3p	CLIP-seq
MIRT2201316	hsa-miR-378g	CLIP-seq
MIRT2201317	hsa-miR-3918	CLIP-seq
MIRT2201318	hsa-miR-3937	CLIP-seq
MIRT894796	hsa-miR-3977	CLIP-seq
MIRT2201319	hsa-miR-429	CLIP-seq
MIRT2201320	hsa-miR-4299	CLIP-seq
MIRT2201321	hsa-miR-4418	CLIP-seq
MIRT2201322	hsa-miR-4420	CLIP-seq
MIRT894809	hsa-miR-4436b-3p	CLIP-seq
MIRT2201323	hsa-miR-4446-3p	CLIP-seq
MIRT2201324	hsa-miR-4456	CLIP-seq
MIRT2201325	hsa-miR-4468	CLIP-seq
MIRT894811	hsa-miR-4471	CLIP-seq
MIRT2201326	hsa-miR-4486	CLIP-seq
MIRT2201327	hsa-miR-4492	CLIP-seq
MIRT2201328	hsa-miR-4498	CLIP-seq
MIRT2201329	hsa-miR-4518	CLIP-seq
MIRT2201330	hsa-miR-4696	CLIP-seq
MIRT894827	hsa-miR-4697-3p	CLIP-seq
MIRT894829	hsa-miR-4711-5p	CLIP-seq
MIRT894830	hsa-miR-4719	CLIP-seq
MIRT2201331	hsa-miR-4724-5p	CLIP-seq
MIRT2201332	hsa-miR-4740-5p	CLIP-seq
MIRT2201333	hsa-miR-4796-5p	CLIP-seq
MIRT2201334	hsa-miR-509-3-5p	CLIP-seq
MIRT2201335	hsa-miR-509-5p	CLIP-seq
MIRT894848	hsa-miR-541	CLIP-seq
MIRT894849	hsa-miR-544	CLIP-seq
MIRT2201336	hsa-miR-548g	CLIP-seq
MIRT2201337	hsa-miR-548q	CLIP-seq
MIRT2201338	hsa-miR-612	CLIP-seq
MIRT2201339	hsa-miR-640	CLIP-seq
MIRT894850	hsa-miR-654-5p	CLIP-seq
MIRT2201340	hsa-miR-665	CLIP-seq
MIRT2201341	hsa-miR-759	CLIP-seq
MIRT2201342	hsa-miR-762	CLIP-seq
MIRT2201343	hsa-miR-767-3p	CLIP-seq
MIRT2201344	hsa-miR-99a	CLIP-seq
MIRT2201345	hsa-miR-99b	CLIP-seq
MIRT894751	hsa-miR-1915	CLIP-seq
MIRT894726	hsa-miR-105	CLIP-seq
MIRT2201299	hsa-miR-1178	CLIP-seq
MIRT2504088	hsa-miR-1185	CLIP-seq
MIRT2504089	hsa-miR-1207-3p	CLIP-seq
MIRT2201300	hsa-miR-1228	CLIP-seq
MIRT894730	hsa-miR-1237	CLIP-seq
MIRT2504090	hsa-miR-124	CLIP-seq
MIRT894731	hsa-miR-1248	CLIP-seq
MIRT894732	hsa-miR-1251	CLIP-seq
MIRT2504091	hsa-miR-125a-3p	CLIP-seq
MIRT894735	hsa-miR-1262	CLIP-seq
MIRT2504092	hsa-miR-1265	CLIP-seq
MIRT2201301	hsa-miR-1266	CLIP-seq
MIRT2504093	hsa-miR-1269	CLIP-seq
MIRT2504094	hsa-miR-1269b	CLIP-seq
MIRT2504095	hsa-miR-1273f	CLIP-seq
MIRT2504096	hsa-miR-1275	CLIP-seq
MIRT894736	hsa-miR-128	CLIP-seq
MIRT2504097	hsa-miR-1288	CLIP-seq
MIRT894737	hsa-miR-1292	CLIP-seq
MIRT2504098	hsa-miR-1299	CLIP-seq
MIRT894741	hsa-miR-141	CLIP-seq
MIRT1965374	hsa-miR-143	CLIP-seq
MIRT894742	hsa-miR-148a	CLIP-seq
MIRT894743	hsa-miR-148b	CLIP-seq
MIRT894744	hsa-miR-149	CLIP-seq
MIRT894745	hsa-miR-152	CLIP-seq
MIRT2504099	hsa-miR-1587	CLIP-seq
MIRT894746	hsa-miR-15a	CLIP-seq
MIRT894747	hsa-miR-15b	CLIP-seq
MIRT894748	hsa-miR-16	CLIP-seq
MIRT2504100	hsa-miR-181a	CLIP-seq
MIRT2504101	hsa-miR-181b	CLIP-seq
MIRT2504102	hsa-miR-181c	CLIP-seq
MIRT2504103	hsa-miR-181d	CLIP-seq
MIRT894751	hsa-miR-1915	CLIP-seq
MIRT894752	hsa-miR-195	CLIP-seq
MIRT2504104	hsa-miR-1976	CLIP-seq
MIRT894755	hsa-miR-200a	CLIP-seq
MIRT2504105	hsa-miR-204	CLIP-seq
MIRT2504106	hsa-miR-211	CLIP-seq
MIRT894757	hsa-miR-2117	CLIP-seq
MIRT894758	hsa-miR-223	CLIP-seq
MIRT894760	hsa-miR-27a	CLIP-seq
MIRT894761	hsa-miR-27b	CLIP-seq
MIRT2504107	hsa-miR-2861	CLIP-seq
MIRT2504108	hsa-miR-3064-5p	CLIP-seq
MIRT2201308	hsa-miR-3126-3p	CLIP-seq
MIRT2201309	hsa-miR-3127-5p	CLIP-seq
MIRT2504109	hsa-miR-3135	CLIP-seq
MIRT2504110	hsa-miR-3140-5p	CLIP-seq
MIRT2504111	hsa-miR-3143	CLIP-seq
MIRT2504112	hsa-miR-3154	CLIP-seq
MIRT2504113	hsa-miR-3165	CLIP-seq
MIRT2504114	hsa-miR-3173-3p	CLIP-seq
MIRT2504115	hsa-miR-3180	CLIP-seq
MIRT2504116	hsa-miR-3180-3p	CLIP-seq
MIRT2504117	hsa-miR-3187-3p	CLIP-seq
MIRT894782	hsa-miR-3194-5p	CLIP-seq
MIRT2504118	hsa-miR-3196	CLIP-seq
MIRT2504119	hsa-miR-3202	CLIP-seq
MIRT2504120	hsa-miR-323b-3p	CLIP-seq
MIRT2504121	hsa-miR-365	CLIP-seq
MIRT2504122	hsa-miR-3657	CLIP-seq
MIRT2201314	hsa-miR-3659	CLIP-seq
MIRT2504123	hsa-miR-3668	CLIP-seq
MIRT894792	hsa-miR-3675-5p	CLIP-seq
MIRT2504124	hsa-miR-3679-5p	CLIP-seq
MIRT2504125	hsa-miR-3714	CLIP-seq
MIRT2504126	hsa-miR-377	CLIP-seq
MIRT2504127	hsa-miR-3910	CLIP-seq
MIRT2201317	hsa-miR-3918	CLIP-seq
MIRT2504128	hsa-miR-3926	CLIP-seq
MIRT2201318	hsa-miR-3937	CLIP-seq
MIRT2504129	hsa-miR-3940-3p	CLIP-seq
MIRT2504130	hsa-miR-3944-5p	CLIP-seq
MIRT894797	hsa-miR-3978	CLIP-seq
MIRT2504131	hsa-miR-423-3p	CLIP-seq
MIRT894798	hsa-miR-424	CLIP-seq
MIRT2504132	hsa-miR-4257	CLIP-seq
MIRT2504133	hsa-miR-4262	CLIP-seq
MIRT2504134	hsa-miR-4263	CLIP-seq
MIRT2504135	hsa-miR-4267	CLIP-seq
MIRT2504136	hsa-miR-4271	CLIP-seq
MIRT2504137	hsa-miR-4279	CLIP-seq
MIRT894801	hsa-miR-4283	CLIP-seq
MIRT2201320	hsa-miR-4299	CLIP-seq
MIRT2504138	hsa-miR-4324	CLIP-seq
MIRT2504139	hsa-miR-4426	CLIP-seq
MIRT894808	hsa-miR-4434	CLIP-seq
MIRT2504140	hsa-miR-4435	CLIP-seq
MIRT894809	hsa-miR-4436b-3p	CLIP-seq
MIRT2201323	hsa-miR-4446-3p	CLIP-seq
MIRT2504141	hsa-miR-4446-5p	CLIP-seq
MIRT2504142	hsa-miR-4447	CLIP-seq
MIRT2504143	hsa-miR-4452	CLIP-seq
MIRT2201324	hsa-miR-4456	CLIP-seq
MIRT2504144	hsa-miR-4459	CLIP-seq
MIRT2201325	hsa-miR-4468	CLIP-seq
MIRT894811	hsa-miR-4471	CLIP-seq
MIRT2504145	hsa-miR-4472	CLIP-seq
MIRT2504146	hsa-miR-4477b	CLIP-seq
MIRT894813	hsa-miR-4481	CLIP-seq
MIRT2504147	hsa-miR-4488	CLIP-seq
MIRT894814	hsa-miR-4489	CLIP-seq
MIRT2201327	hsa-miR-4492	CLIP-seq
MIRT894815	hsa-miR-4496	CLIP-seq
MIRT2201328	hsa-miR-4498	CLIP-seq
MIRT2504148	hsa-miR-4504	CLIP-seq
MIRT2504149	hsa-miR-4505	CLIP-seq
MIRT2504150	hsa-miR-4506	CLIP-seq
MIRT2504151	hsa-miR-4515	CLIP-seq
MIRT894816	hsa-miR-4516	CLIP-seq
MIRT2201329	hsa-miR-4518	CLIP-seq
MIRT2504152	hsa-miR-4520a-3p	CLIP-seq
MIRT2504153	hsa-miR-4520b-3p	CLIP-seq
MIRT2504154	hsa-miR-4525	CLIP-seq
MIRT894817	hsa-miR-4531	CLIP-seq
MIRT2504155	hsa-miR-4532	CLIP-seq
MIRT2504156	hsa-miR-4533	CLIP-seq
MIRT2504157	hsa-miR-4539	CLIP-seq
MIRT894820	hsa-miR-4640-5p	CLIP-seq
MIRT894822	hsa-miR-4646-5p	CLIP-seq
MIRT2504158	hsa-miR-4647	CLIP-seq
MIRT2504159	hsa-miR-4655-5p	CLIP-seq
MIRT2504160	hsa-miR-4662b	CLIP-seq
MIRT2504161	hsa-miR-4665-5p	CLIP-seq
MIRT2504162	hsa-miR-4674	CLIP-seq
MIRT894826	hsa-miR-4684-5p	CLIP-seq
MIRT2504163	hsa-miR-4685-5p	CLIP-seq
MIRT2504164	hsa-miR-4687-5p	CLIP-seq
MIRT2504165	hsa-miR-4694-3p	CLIP-seq
MIRT894827	hsa-miR-4697-3p	CLIP-seq
MIRT2504166	hsa-miR-4697-5p	CLIP-seq
MIRT894828	hsa-miR-4701-3p	CLIP-seq
MIRT2504167	hsa-miR-4701-5p	CLIP-seq
MIRT2504168	hsa-miR-4707-3p	CLIP-seq
MIRT2504169	hsa-miR-4708-5p	CLIP-seq
MIRT894829	hsa-miR-4711-5p	CLIP-seq
MIRT894830	hsa-miR-4719	CLIP-seq
MIRT2504170	hsa-miR-4723-5p	CLIP-seq
MIRT2504171	hsa-miR-4725-3p	CLIP-seq
MIRT894831	hsa-miR-4726-5p	CLIP-seq
MIRT2504172	hsa-miR-4728-3p	CLIP-seq
MIRT2201332	hsa-miR-4740-5p	CLIP-seq
MIRT894832	hsa-miR-4745-5p	CLIP-seq
MIRT2504173	hsa-miR-4747-3p	CLIP-seq
MIRT2504174	hsa-miR-4755-3p	CLIP-seq
MIRT2504175	hsa-miR-4755-5p	CLIP-seq
MIRT894833	hsa-miR-4758-5p	CLIP-seq
MIRT2504176	hsa-miR-4764-5p	CLIP-seq
MIRT2504177	hsa-miR-4766-5p	CLIP-seq
MIRT894836	hsa-miR-4769-3p	CLIP-seq
MIRT1965381	hsa-miR-4770	CLIP-seq
MIRT2504178	hsa-miR-4771	CLIP-seq
MIRT2504179	hsa-miR-4794	CLIP-seq
MIRT2504180	hsa-miR-486-3p	CLIP-seq
MIRT2504181	hsa-miR-488	CLIP-seq
MIRT894840	hsa-miR-497	CLIP-seq
MIRT2504182	hsa-miR-499a-5p	CLIP-seq
MIRT2504183	hsa-miR-506	CLIP-seq
MIRT2504184	hsa-miR-511	CLIP-seq
MIRT894841	hsa-miR-516a-3p	CLIP-seq
MIRT2504185	hsa-miR-542-3p	CLIP-seq
MIRT2504186	hsa-miR-543	CLIP-seq
MIRT894849	hsa-miR-544	CLIP-seq
MIRT2504187	hsa-miR-548aa	CLIP-seq
MIRT2504188	hsa-miR-548an	CLIP-seq
MIRT2504189	hsa-miR-548p	CLIP-seq
MIRT2201337	hsa-miR-548q	CLIP-seq
MIRT2504190	hsa-miR-548s	CLIP-seq
MIRT2504191	hsa-miR-552	CLIP-seq
MIRT2504192	hsa-miR-562	CLIP-seq
MIRT2504193	hsa-miR-576-5p	CLIP-seq
MIRT2504194	hsa-miR-588	CLIP-seq
MIRT2504195	hsa-miR-615-5p	CLIP-seq
MIRT2504196	hsa-miR-623	CLIP-seq
MIRT2504197	hsa-miR-625	CLIP-seq
MIRT2504198	hsa-miR-626	CLIP-seq
MIRT2201339	hsa-miR-640	CLIP-seq
MIRT2504199	hsa-miR-646	CLIP-seq
MIRT2201340	hsa-miR-665	CLIP-seq
MIRT2201341	hsa-miR-759	CLIP-seq
MIRT2504200	hsa-miR-760	CLIP-seq
MIRT2201342	hsa-miR-762	CLIP-seq
MIRT2504201	hsa-miR-764	CLIP-seq
MIRT2504202	hsa-miR-873	CLIP-seq
MIRT2504203	hsa-miR-875-3p	CLIP-seq
MIRT2504204	hsa-miR-890	CLIP-seq
MIRT894853	hsa-miR-9	CLIP-seq
MIRT2201299	hsa-miR-1178	CLIP-seq
MIRT2201300	hsa-miR-1228	CLIP-seq
MIRT894730	hsa-miR-1237	CLIP-seq
MIRT2504090	hsa-miR-124	CLIP-seq
MIRT894731	hsa-miR-1248	CLIP-seq
MIRT894732	hsa-miR-1251	CLIP-seq
MIRT2504091	hsa-miR-125a-3p	CLIP-seq
MIRT894735	hsa-miR-1262	CLIP-seq
MIRT2504092	hsa-miR-1265	CLIP-seq
MIRT2201301	hsa-miR-1266	CLIP-seq
MIRT2504095	hsa-miR-1273f	CLIP-seq
MIRT2504096	hsa-miR-1275	CLIP-seq
MIRT894736	hsa-miR-128	CLIP-seq
MIRT894741	hsa-miR-141	CLIP-seq
MIRT1965374	hsa-miR-143	CLIP-seq
MIRT2504100	hsa-miR-181a	CLIP-seq
MIRT2504101	hsa-miR-181b	CLIP-seq
MIRT2504102	hsa-miR-181c	CLIP-seq
MIRT2504103	hsa-miR-181d	CLIP-seq
MIRT894751	hsa-miR-1915	CLIP-seq
MIRT2504104	hsa-miR-1976	CLIP-seq
MIRT894755	hsa-miR-200a	CLIP-seq
MIRT2504105	hsa-miR-204	CLIP-seq
MIRT2504106	hsa-miR-211	CLIP-seq
MIRT894757	hsa-miR-2117	CLIP-seq
MIRT894760	hsa-miR-27a	CLIP-seq
MIRT894761	hsa-miR-27b	CLIP-seq
MIRT2504107	hsa-miR-2861	CLIP-seq
MIRT2201309	hsa-miR-3127-5p	CLIP-seq
MIRT2504109	hsa-miR-3135	CLIP-seq
MIRT2504111	hsa-miR-3143	CLIP-seq
MIRT2504112	hsa-miR-3154	CLIP-seq
MIRT2504114	hsa-miR-3173-3p	CLIP-seq
MIRT2504117	hsa-miR-3187-3p	CLIP-seq
MIRT2504119	hsa-miR-3202	CLIP-seq
MIRT2504120	hsa-miR-323b-3p	CLIP-seq
MIRT2504121	hsa-miR-365	CLIP-seq
MIRT2201314	hsa-miR-3659	CLIP-seq
MIRT2504123	hsa-miR-3668	CLIP-seq
MIRT894792	hsa-miR-3675-5p	CLIP-seq
MIRT2504125	hsa-miR-3714	CLIP-seq
MIRT2504126	hsa-miR-377	CLIP-seq
MIRT2504127	hsa-miR-3910	CLIP-seq
MIRT2201317	hsa-miR-3918	CLIP-seq
MIRT2504128	hsa-miR-3926	CLIP-seq
MIRT2201318	hsa-miR-3937	CLIP-seq
MIRT2504129	hsa-miR-3940-3p	CLIP-seq
MIRT2504130	hsa-miR-3944-5p	CLIP-seq
MIRT2504131	hsa-miR-423-3p	CLIP-seq
MIRT2504133	hsa-miR-4262	CLIP-seq
MIRT2504134	hsa-miR-4263	CLIP-seq
MIRT2504136	hsa-miR-4271	CLIP-seq
MIRT2504137	hsa-miR-4279	CLIP-seq
MIRT894801	hsa-miR-4283	CLIP-seq
MIRT2504138	hsa-miR-4324	CLIP-seq
MIRT2504139	hsa-miR-4426	CLIP-seq
MIRT2504140	hsa-miR-4435	CLIP-seq
MIRT894809	hsa-miR-4436b-3p	CLIP-seq
MIRT2201323	hsa-miR-4446-3p	CLIP-seq
MIRT2504141	hsa-miR-4446-5p	CLIP-seq
MIRT2504142	hsa-miR-4447	CLIP-seq
MIRT2504143	hsa-miR-4452	CLIP-seq
MIRT2201325	hsa-miR-4468	CLIP-seq
MIRT2504145	hsa-miR-4472	CLIP-seq
MIRT2504146	hsa-miR-4477b	CLIP-seq
MIRT894814	hsa-miR-4489	CLIP-seq
MIRT2201327	hsa-miR-4492	CLIP-seq
MIRT894815	hsa-miR-4496	CLIP-seq
MIRT2201328	hsa-miR-4498	CLIP-seq
MIRT2504148	hsa-miR-4504	CLIP-seq
MIRT2504149	hsa-miR-4505	CLIP-seq
MIRT2504150	hsa-miR-4506	CLIP-seq
MIRT2201329	hsa-miR-4518	CLIP-seq
MIRT2504152	hsa-miR-4520a-3p	CLIP-seq
MIRT2504153	hsa-miR-4520b-3p	CLIP-seq
MIRT2504154	hsa-miR-4525	CLIP-seq
MIRT2504156	hsa-miR-4533	CLIP-seq
MIRT2504157	hsa-miR-4539	CLIP-seq
MIRT894820	hsa-miR-4640-5p	CLIP-seq
MIRT2504158	hsa-miR-4647	CLIP-seq
MIRT2504159	hsa-miR-4655-5p	CLIP-seq
MIRT2504160	hsa-miR-4662b	CLIP-seq
MIRT2504161	hsa-miR-4665-5p	CLIP-seq
MIRT894826	hsa-miR-4684-5p	CLIP-seq
MIRT2504163	hsa-miR-4685-5p	CLIP-seq
MIRT2504164	hsa-miR-4687-5p	CLIP-seq
MIRT2504165	hsa-miR-4694-3p	CLIP-seq
MIRT894828	hsa-miR-4701-3p	CLIP-seq
MIRT2504167	hsa-miR-4701-5p	CLIP-seq
MIRT2504169	hsa-miR-4708-5p	CLIP-seq
MIRT2504170	hsa-miR-4723-5p	CLIP-seq
MIRT2504171	hsa-miR-4725-3p	CLIP-seq
MIRT894831	hsa-miR-4726-5p	CLIP-seq
MIRT2504172	hsa-miR-4728-3p	CLIP-seq
MIRT2504173	hsa-miR-4747-3p	CLIP-seq
MIRT2504174	hsa-miR-4755-3p	CLIP-seq
MIRT2504175	hsa-miR-4755-5p	CLIP-seq
MIRT2504176	hsa-miR-4764-5p	CLIP-seq
MIRT894836	hsa-miR-4769-3p	CLIP-seq
MIRT1965381	hsa-miR-4770	CLIP-seq
MIRT2504178	hsa-miR-4771	CLIP-seq
MIRT2504180	hsa-miR-486-3p	CLIP-seq
MIRT2504181	hsa-miR-488	CLIP-seq
MIRT2504182	hsa-miR-499a-5p	CLIP-seq
MIRT2504183	hsa-miR-506	CLIP-seq
MIRT894841	hsa-miR-516a-3p	CLIP-seq
MIRT2504185	hsa-miR-542-3p	CLIP-seq
MIRT2504186	hsa-miR-543	CLIP-seq
MIRT2504187	hsa-miR-548aa	CLIP-seq
MIRT2504188	hsa-miR-548an	CLIP-seq
MIRT2504189	hsa-miR-548p	CLIP-seq
MIRT2504190	hsa-miR-548s	CLIP-seq
MIRT2504191	hsa-miR-552	CLIP-seq
MIRT2504192	hsa-miR-562	CLIP-seq
MIRT2504193	hsa-miR-576-5p	CLIP-seq
MIRT2504194	hsa-miR-588	CLIP-seq
MIRT2504195	hsa-miR-615-5p	CLIP-seq
MIRT2504196	hsa-miR-623	CLIP-seq
MIRT2504197	hsa-miR-625	CLIP-seq
MIRT2201339	hsa-miR-640	CLIP-seq
MIRT2201340	hsa-miR-665	CLIP-seq
MIRT2201341	hsa-miR-759	CLIP-seq
MIRT2201342	hsa-miR-762	CLIP-seq
MIRT2504201	hsa-miR-764	CLIP-seq
MIRT2504202	hsa-miR-873	CLIP-seq
MIRT2504204	hsa-miR-890	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005247	Function	Voltage-gated chloride channel activity	IBA
GO:0005247	Function	Voltage-gated chloride channel activity	IDA	20466723
GO:0005247	Function	Voltage-gated chloride channel activity	IEA
GO:0005247	Function	Voltage-gated chloride channel activity	NAS	8543009, 9224655
GO:0005254	Function	Chloride channel activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005765	Component	Lysosomal membrane	HDA	17897319
GO:0005768	Component	Endosome	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006821	Process	Chloride transport	IBA
GO:0006821	Process	Chloride transport	IDA	20466723
GO:0006821	Process	Chloride transport	IEA
GO:0006821	Process	Chloride transport	NAS	8543009, 9224655
GO:0006884	Process	Cell volume homeostasis	NAS	8543009, 9224655
GO:0007165	Process	Signal transduction	NAS	8543009, 9224655
GO:0009612	Process	Response to mechanical stimulus	IEA
GO:0010008	Component	Endosome membrane	TAS
GO:0015108	Function	Chloride transmembrane transporter activity	IEA
GO:0015297	Function	Antiporter activity	IEA
GO:0015297	Function	Antiporter activity	TAS
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	8543009, 9224655
GO:0031902	Component	Late endosome membrane	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	TAS
GO:0055085	Process	Transmembrane transport	IEA
GO:1902476	Process	Chloride transmembrane transport	IEA

Other IDs

• MIM: 602726
• HGNC: 2024
• e!Ensembl: ENSG00000011021

Protein

• UniProt ID: P51797
• Protein name: H(+)/Cl(-) exchange transporter 6 (Chloride channel protein 6) (ClC-6) (Chloride transport protein 6)
• Protein function: Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled ani
• PDB: 8JPJ, 8JPO, 8JPR
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00654	Voltage_CLC	138 → 570	Voltage gated chloride channel	Family
  PF00571	CBS	601 → 645	CBS domain	Domain
  PF00571	CBS	801 → 857	CBS domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney. {ECO:0000269|PubMed:10198195, ECO:
• Sequence:

  MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP
  YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC
  SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL
  LCKVLGVLFSVAGGLFVEKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD
  FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF
  GSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAK
  YRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSSSQIGNDSFQLQVTED
  VNSSIKTFFCPNDTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTY
  GISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISL
  TVILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLR
  ASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFK
  KSSILTRAGEQRKRSQSMKSYPSSELRNMCDEHIASEEPAEKEDLLQQMLERRYTPYPNL
  YPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAED
  YPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNA
  VGEIVGIITRHNLTYEFLQARLRQHYQTI

• Sequence length: 869

Pathways

Reactome:

Stimuli-sensing channels
Signaling by BRAF and RAF fusions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Adrenocortical carcinoma, hereditary	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CEROID LIPOFUSCINOSIS, NEURONAL, 15	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC ISCHEMIC HEART DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLCN6-RELATED CHILDHOOD-ONSET PROGRESSIVE NEURODEGENERATION-PERIPHERAL NEUROPATHY SYNDROME	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLCN6-related disorder	Likely benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERIOSCLEROSIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY HEART DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLOBAL DEVELOPMENTAL DELAY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOVEMENT DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL ISCHEMIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodegeneration, childhood-onset, with hypotonia, respiratory insufficiency, and brain imaging abnormalities	Uncertain significance; Benign; Likely benign; Conflicting classifications of pathogenicity	ClinVar ClinGen, ClinVar, Disgenet, GWAS catalog ClinGen, ClinVar, Disgenet, GWAS catalog	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Papillary renal cell carcinoma type 1	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PREECLAMPSIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uveal melanoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Asthma	Asthma	Pubtator	32512817	Associate	★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation, Familial, 6	Atrial Fibrillation	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
ATRIAL STANDSTILL 2	Atrial standstill	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	38095064	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsies, Partial	Epilepsy	BEFREE	25794116		★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	Pubtator	28074849	Associate	★☆☆☆☆ Found in Text Mining only
Febrile Convulsions	Febrile seizures	BEFREE	25794116		★☆☆☆☆ Found in Text Mining only
Frontotemporal Dementia	Frontotemporal dementia	Pubtator	33737586	Associate	★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	34126931	Associate	★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	24006081, 26658788		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	35262198, 37831762, 38095064	Associate	★☆☆☆☆ Found in Text Mining only
Neuronal Ceroid-Lipofuscinoses	Neuronal Ceroid Lipofuscinosis	BEFREE	16950870		★☆☆☆☆ Found in Text Mining only
Osteopetrosis	Osteopetrosis	Pubtator	37937509	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	36246902	Associate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	GWASCAT_DG	25854761		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Spasms Infantile	Infantile spasms	Pubtator	29667327	Associate	★☆☆☆☆ Found in Text Mining only
Stroke	Stroke	Pubtator	25452597	Associate	★☆☆☆☆ Found in Text Mining only
Vision Disorders	Visual disorder	Pubtator	38095064	Associate	★☆☆☆☆ Found in Text Mining only