Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	117143
Gene name	Transcriptional adaptor 1
Gene symbol	TADA1
Synonyms (NCBI Gene)	ADA1HFI1STAF42TADA1LhADA1
Chromosome	1
Chromosome location	1q24.1
Summary	TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr

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Show/Hide all (227)

miRTarBase ID	miRNA	Experiments
MIRT1408627	hsa-miR-1245	CLIP-seq
MIRT1408628	hsa-miR-1279	CLIP-seq
MIRT1408629	hsa-miR-1284	CLIP-seq
MIRT1408630	hsa-miR-1323	CLIP-seq
MIRT1408631	hsa-miR-135a	CLIP-seq
MIRT1408632	hsa-miR-135b	CLIP-seq
MIRT1408633	hsa-miR-141	CLIP-seq
MIRT1408634	hsa-miR-150	CLIP-seq
MIRT1408635	hsa-miR-154	CLIP-seq
MIRT1408636	hsa-miR-190	CLIP-seq
MIRT1408637	hsa-miR-190b	CLIP-seq
MIRT1408638	hsa-miR-1914	CLIP-seq
MIRT1408639	hsa-miR-200a	CLIP-seq
MIRT1408640	hsa-miR-202	CLIP-seq
MIRT1408641	hsa-miR-23a	CLIP-seq
MIRT1408642	hsa-miR-23b	CLIP-seq
MIRT1408643	hsa-miR-23c	CLIP-seq
MIRT1408644	hsa-miR-3074-5p	CLIP-seq
MIRT1408645	hsa-miR-3115	CLIP-seq
MIRT1408646	hsa-miR-3120-3p	CLIP-seq
MIRT1408647	hsa-miR-3173-3p	CLIP-seq
MIRT1408648	hsa-miR-3200-5p	CLIP-seq
MIRT1408649	hsa-miR-361-5p	CLIP-seq
MIRT1408650	hsa-miR-3617	CLIP-seq
MIRT1408651	hsa-miR-3671	CLIP-seq
MIRT1408652	hsa-miR-3691-3p	CLIP-seq
MIRT1408653	hsa-miR-370	CLIP-seq
MIRT1408654	hsa-miR-383	CLIP-seq
MIRT1408655	hsa-miR-3920	CLIP-seq
MIRT1408656	hsa-miR-3945	CLIP-seq
MIRT1408657	hsa-miR-3973	CLIP-seq
MIRT1408658	hsa-miR-3976	CLIP-seq
MIRT1408659	hsa-miR-4253	CLIP-seq
MIRT1408660	hsa-miR-4434	CLIP-seq
MIRT1408661	hsa-miR-4450	CLIP-seq
MIRT1408662	hsa-miR-4464	CLIP-seq
MIRT1408663	hsa-miR-4495	CLIP-seq
MIRT1408664	hsa-miR-4496	CLIP-seq
MIRT1408665	hsa-miR-4501	CLIP-seq
MIRT1408666	hsa-miR-4509	CLIP-seq
MIRT1408667	hsa-miR-4516	CLIP-seq
MIRT1408668	hsa-miR-4525	CLIP-seq
MIRT1408669	hsa-miR-4531	CLIP-seq
MIRT1408670	hsa-miR-4650-3p	CLIP-seq
MIRT1408671	hsa-miR-4653-3p	CLIP-seq
MIRT1408672	hsa-miR-4672	CLIP-seq
MIRT1408673	hsa-miR-4704-5p	CLIP-seq
MIRT1408674	hsa-miR-4713-5p	CLIP-seq
MIRT1408675	hsa-miR-4716-3p	CLIP-seq
MIRT1408676	hsa-miR-4738-3p	CLIP-seq
MIRT1408677	hsa-miR-4747-5p	CLIP-seq
MIRT1408678	hsa-miR-4748	CLIP-seq
MIRT1408679	hsa-miR-4772-5p	CLIP-seq
MIRT1408680	hsa-miR-4789-5p	CLIP-seq
MIRT1408681	hsa-miR-495	CLIP-seq
MIRT1408682	hsa-miR-513a-3p	CLIP-seq
MIRT1408683	hsa-miR-513b	CLIP-seq
MIRT1408684	hsa-miR-520g	CLIP-seq
MIRT1408685	hsa-miR-520h	CLIP-seq
MIRT1408686	hsa-miR-532-3p	CLIP-seq
MIRT1408687	hsa-miR-548a-5p	CLIP-seq
MIRT1408688	hsa-miR-548ab	CLIP-seq
MIRT1408689	hsa-miR-548ak	CLIP-seq
MIRT1408690	hsa-miR-548b-5p	CLIP-seq
MIRT1408691	hsa-miR-548c-5p	CLIP-seq
MIRT1408692	hsa-miR-548d-5p	CLIP-seq
MIRT1408693	hsa-miR-548h	CLIP-seq
MIRT1408694	hsa-miR-548i	CLIP-seq
MIRT1408695	hsa-miR-548j	CLIP-seq
MIRT1408696	hsa-miR-548k	CLIP-seq
MIRT1408697	hsa-miR-548l	CLIP-seq
MIRT1408698	hsa-miR-548o	CLIP-seq
MIRT1408699	hsa-miR-548w	CLIP-seq
MIRT1408700	hsa-miR-548y	CLIP-seq
MIRT1408701	hsa-miR-553	CLIP-seq
MIRT1408702	hsa-miR-559	CLIP-seq
MIRT1408703	hsa-miR-561	CLIP-seq
MIRT1408704	hsa-miR-582-3p	CLIP-seq
MIRT1408705	hsa-miR-587	CLIP-seq
MIRT1408706	hsa-miR-627	CLIP-seq
MIRT1408707	hsa-miR-641	CLIP-seq
MIRT1408708	hsa-miR-656	CLIP-seq
MIRT1408709	hsa-miR-7	CLIP-seq
MIRT1408710	hsa-miR-802	CLIP-seq
MIRT1408711	hsa-miR-888	CLIP-seq
MIRT1408712	hsa-miR-892a	CLIP-seq
MIRT1408713	hsa-miR-944	CLIP-seq
MIRT1408627	hsa-miR-1245	CLIP-seq
MIRT1408628	hsa-miR-1279	CLIP-seq
MIRT1408629	hsa-miR-1284	CLIP-seq
MIRT1408633	hsa-miR-141	CLIP-seq
MIRT2122575	hsa-miR-151-3p	CLIP-seq
MIRT1408635	hsa-miR-154	CLIP-seq
MIRT1408638	hsa-miR-1914	CLIP-seq
MIRT1408639	hsa-miR-200a	CLIP-seq
MIRT1408641	hsa-miR-23a	CLIP-seq
MIRT1408642	hsa-miR-23b	CLIP-seq
MIRT1408643	hsa-miR-23c	CLIP-seq
MIRT1408644	hsa-miR-3074-5p	CLIP-seq
MIRT2122576	hsa-miR-3157-5p	CLIP-seq
MIRT1408649	hsa-miR-361-5p	CLIP-seq
MIRT1408652	hsa-miR-3691-3p	CLIP-seq
MIRT1408662	hsa-miR-4464	CLIP-seq
MIRT1408664	hsa-miR-4496	CLIP-seq
MIRT1408671	hsa-miR-4653-3p	CLIP-seq
MIRT1408672	hsa-miR-4672	CLIP-seq
MIRT1408673	hsa-miR-4704-5p	CLIP-seq
MIRT1408676	hsa-miR-4738-3p	CLIP-seq
MIRT1408678	hsa-miR-4748	CLIP-seq
MIRT2122577	hsa-miR-4777-5p	CLIP-seq
MIRT1408680	hsa-miR-4789-5p	CLIP-seq
MIRT2122578	hsa-miR-518d-5p	CLIP-seq
MIRT2122579	hsa-miR-519b-5p	CLIP-seq
MIRT2122580	hsa-miR-519c-5p	CLIP-seq
MIRT2122581	hsa-miR-520c-5p	CLIP-seq
MIRT2122582	hsa-miR-526a	CLIP-seq
MIRT1408705	hsa-miR-587	CLIP-seq
MIRT2122583	hsa-miR-590-3p	CLIP-seq
MIRT1408710	hsa-miR-802	CLIP-seq
MIRT1408711	hsa-miR-888	CLIP-seq
MIRT1408713	hsa-miR-944	CLIP-seq
MIRT1408629	hsa-miR-1284	CLIP-seq
MIRT1408631	hsa-miR-135a	CLIP-seq
MIRT1408632	hsa-miR-135b	CLIP-seq
MIRT2344974	hsa-miR-140-3p	CLIP-seq
MIRT1408633	hsa-miR-141	CLIP-seq
MIRT2122575	hsa-miR-151-3p	CLIP-seq
MIRT1408635	hsa-miR-154	CLIP-seq
MIRT1408636	hsa-miR-190	CLIP-seq
MIRT1408637	hsa-miR-190b	CLIP-seq
MIRT1408639	hsa-miR-200a	CLIP-seq
MIRT1408640	hsa-miR-202	CLIP-seq
MIRT2344975	hsa-miR-203	CLIP-seq
MIRT1408641	hsa-miR-23a	CLIP-seq
MIRT1408642	hsa-miR-23b	CLIP-seq
MIRT1408643	hsa-miR-23c	CLIP-seq
MIRT1408646	hsa-miR-3120-3p	CLIP-seq
MIRT2122576	hsa-miR-3157-5p	CLIP-seq
MIRT2344976	hsa-miR-3166	CLIP-seq
MIRT1408647	hsa-miR-3173-3p	CLIP-seq
MIRT1408648	hsa-miR-3200-5p	CLIP-seq
MIRT2344977	hsa-miR-3545-3p	CLIP-seq
MIRT1408649	hsa-miR-361-5p	CLIP-seq
MIRT1408651	hsa-miR-3671	CLIP-seq
MIRT2344978	hsa-miR-3714	CLIP-seq
MIRT1408655	hsa-miR-3920	CLIP-seq
MIRT2344979	hsa-miR-4266	CLIP-seq
MIRT1408663	hsa-miR-4495	CLIP-seq
MIRT1408664	hsa-miR-4496	CLIP-seq
MIRT1408665	hsa-miR-4501	CLIP-seq
MIRT1408666	hsa-miR-4509	CLIP-seq
MIRT1408670	hsa-miR-4650-3p	CLIP-seq
MIRT1408672	hsa-miR-4672	CLIP-seq
MIRT2344980	hsa-miR-4698	CLIP-seq
MIRT1408673	hsa-miR-4704-5p	CLIP-seq
MIRT1408676	hsa-miR-4738-3p	CLIP-seq
MIRT2344981	hsa-miR-4771	CLIP-seq
MIRT2122577	hsa-miR-4777-5p	CLIP-seq
MIRT1408680	hsa-miR-4789-5p	CLIP-seq
MIRT1408683	hsa-miR-513b	CLIP-seq
MIRT2122578	hsa-miR-518d-5p	CLIP-seq
MIRT2122579	hsa-miR-519b-5p	CLIP-seq
MIRT2122580	hsa-miR-519c-5p	CLIP-seq
MIRT2122581	hsa-miR-520c-5p	CLIP-seq
MIRT2122582	hsa-miR-526a	CLIP-seq
MIRT1408687	hsa-miR-548a-5p	CLIP-seq
MIRT1408688	hsa-miR-548ab	CLIP-seq
MIRT1408689	hsa-miR-548ak	CLIP-seq
MIRT2344982	hsa-miR-548an	CLIP-seq
MIRT1408690	hsa-miR-548b-5p	CLIP-seq
MIRT1408691	hsa-miR-548c-5p	CLIP-seq
MIRT1408692	hsa-miR-548d-5p	CLIP-seq
MIRT1408693	hsa-miR-548h	CLIP-seq
MIRT1408694	hsa-miR-548i	CLIP-seq
MIRT1408695	hsa-miR-548j	CLIP-seq
MIRT1408696	hsa-miR-548k	CLIP-seq
MIRT1408697	hsa-miR-548l	CLIP-seq
MIRT1408699	hsa-miR-548w	CLIP-seq
MIRT1408700	hsa-miR-548y	CLIP-seq
MIRT1408702	hsa-miR-559	CLIP-seq
MIRT1408704	hsa-miR-582-3p	CLIP-seq
MIRT1408705	hsa-miR-587	CLIP-seq
MIRT2122583	hsa-miR-590-3p	CLIP-seq
MIRT2344983	hsa-miR-651	CLIP-seq
MIRT1408708	hsa-miR-656	CLIP-seq
MIRT1408710	hsa-miR-802	CLIP-seq
MIRT1408711	hsa-miR-888	CLIP-seq
MIRT1408712	hsa-miR-892a	CLIP-seq
MIRT1408713	hsa-miR-944	CLIP-seq
MIRT2638105	hsa-miR-1265	CLIP-seq
MIRT1408629	hsa-miR-1284	CLIP-seq
MIRT2638106	hsa-miR-181a	CLIP-seq
MIRT2638107	hsa-miR-181b	CLIP-seq
MIRT2638108	hsa-miR-181c	CLIP-seq
MIRT2638109	hsa-miR-181d	CLIP-seq
MIRT2638110	hsa-miR-2392	CLIP-seq
MIRT1408653	hsa-miR-370	CLIP-seq
MIRT2638111	hsa-miR-375	CLIP-seq
MIRT1408654	hsa-miR-383	CLIP-seq
MIRT2638112	hsa-miR-4262	CLIP-seq
MIRT2638113	hsa-miR-4273	CLIP-seq
MIRT1408661	hsa-miR-4450	CLIP-seq
MIRT1408668	hsa-miR-4525	CLIP-seq
MIRT2638114	hsa-miR-4666-5p	CLIP-seq
MIRT2638115	hsa-miR-4677-5p	CLIP-seq
MIRT1408675	hsa-miR-4716-3p	CLIP-seq
MIRT2638116	hsa-miR-4719	CLIP-seq
MIRT2638117	hsa-miR-4735-5p	CLIP-seq
MIRT1408679	hsa-miR-4772-5p	CLIP-seq
MIRT1408683	hsa-miR-513b	CLIP-seq
MIRT2638118	hsa-miR-576-5p	CLIP-seq
MIRT2638119	hsa-miR-600	CLIP-seq
MIRT1408629	hsa-miR-1284	CLIP-seq
MIRT2638106	hsa-miR-181a	CLIP-seq
MIRT2638107	hsa-miR-181b	CLIP-seq
MIRT2638108	hsa-miR-181c	CLIP-seq
MIRT2638109	hsa-miR-181d	CLIP-seq
MIRT1408653	hsa-miR-370	CLIP-seq
MIRT1408654	hsa-miR-383	CLIP-seq
MIRT2638112	hsa-miR-4262	CLIP-seq
MIRT1408661	hsa-miR-4450	CLIP-seq
MIRT1408668	hsa-miR-4525	CLIP-seq
MIRT1408675	hsa-miR-4716-3p	CLIP-seq
MIRT2638116	hsa-miR-4719	CLIP-seq
MIRT1408679	hsa-miR-4772-5p	CLIP-seq
MIRT1408683	hsa-miR-513b	CLIP-seq
MIRT2638118	hsa-miR-576-5p	CLIP-seq

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000124	Component	SAGA complex	IBA
GO:0000124	Component	SAGA complex	IDA	11564863
GO:0000124	Component	SAGA complex	NAS	19114550
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	11564863
GO:0005634	Component	Nucleus	IDA	11564863
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005925	Component	Focal adhesion	IDA
GO:0006282	Process	Regulation of DNA repair	NAS	11564863
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0043484	Process	Regulation of RNA splicing	NAS	11564863
GO:0045893	Process	Positive regulation of DNA-templated transcription	NAS	18206972
GO:0070461	Component	SAGA-type complex	IEA

MIM	HGNC	e!Ensembl
612763	30631	ENSG00000152382

Q96BN2

Protein name

Transcriptional adapter 1 (SPT3-associated factor 42) (STAF42) (Transcriptional adapter 1-like protein)

Protein function

Probably involved in transcriptional regulation.

PDB

7KTR , 7KTS , 8H7G

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12767	SAGA-Tad1	6 → 129	Transcriptional regulator of RNA polII, SAGA, subunit	Family
PF12767	SAGA-Tad1	114 → 194	Transcriptional regulator of RNA polII, SAGA, subunit	Family

Sequence

MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHN
DFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLS
GAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVE
NHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCA
GQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALN
IERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC

Sequence length

335

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Nonpapillary renal cell carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (34)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	30581348		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	30581348		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	30641086		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	12632419, 20943049	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	16754522		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	30641086		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	11121182		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	35663977	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinosarcoma	Carcinoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	30581348		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30210694		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	17287605, 20581655		★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	12632419		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	20581655		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	20581655		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	19789510, 20480728, 20805743, 25125338		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	15281007		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	35663977	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	30192643	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild Mental Retardation	Mental retardation	BEFREE	16970880		★★★★★ ★☆☆☆☆ Found in Text Mining only
MYOTONIC DYSTROPHY 1	Myotonic dystrophy	BEFREE	20480728		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Diseases	Ovarian diseases	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	26980102		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	12632419, 20943049		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Severe Combined Immunodeficiency	Severe combined immunodeficiency	Pubtator	15926889, 20147294, 35967411	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Severe intellectual disability	Mental retardation	BEFREE	16970880		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	35663977	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TADA1 (transcriptional adaptor 1)