EVI5L (ecotropic viral integration site 5 like)

Gene

• Entrez ID: 115704
• Gene name: Ecotropic viral integration site 5 like
• Gene symbol: EVI5L
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT253418	hsa-miR-449b-5p	PAR-CLIP	21572407
MIRT253412	hsa-miR-34a-5p	PAR-CLIP	21572407
MIRT253414	hsa-miR-34c-5p	PAR-CLIP	21572407
MIRT253415	hsa-miR-449a	PAR-CLIP	21572407
MIRT253410	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT253411	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT253413	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT253416	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT349239	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT349235	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT349236	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT558061	hsa-miR-4716-3p	PAR-CLIP	21572407
MIRT558060	hsa-miR-6794-5p	PAR-CLIP	21572407
MIRT558058	hsa-miR-6805-5p	PAR-CLIP	21572407
MIRT558059	hsa-miR-6732-5p	PAR-CLIP	21572407
MIRT295049	hsa-miR-4280	PAR-CLIP	21572407
MIRT253417	hsa-miR-648	PAR-CLIP	21572407
MIRT253426	hsa-miR-4698	PAR-CLIP	21572407
MIRT349241	hsa-miR-4514	PAR-CLIP	21572407
MIRT349242	hsa-miR-4692	PAR-CLIP	21572407
MIRT253423	hsa-miR-4302	PAR-CLIP	21572407
MIRT253430	hsa-miR-7112-5p	PAR-CLIP	21572407
MIRT253424	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT253420	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT253421	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT253422	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT253419	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT253428	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT558057	hsa-miR-1908-5p	PAR-CLIP	21572407
MIRT558056	hsa-miR-663a	PAR-CLIP	21572407
MIRT558055	hsa-miR-6787-5p	PAR-CLIP	21572407
MIRT558054	hsa-miR-1268a	PAR-CLIP	21572407
MIRT558053	hsa-miR-1268b	PAR-CLIP	21572407
MIRT558052	hsa-miR-1237-5p	PAR-CLIP	21572407
MIRT558051	hsa-miR-4488	PAR-CLIP	21572407
MIRT558050	hsa-miR-4697-5p	PAR-CLIP	21572407
MIRT295048	hsa-miR-4278	PAR-CLIP	21572407
MIRT253427	hsa-miR-548aw	PAR-CLIP	21572407
MIRT295047	hsa-miR-135b-3p	PAR-CLIP	21572407
MIRT477216	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT477214	hsa-miR-4459	PAR-CLIP	23592263
MIRT477215	hsa-miR-665	PAR-CLIP	23592263
MIRT477213	hsa-miR-6089	PAR-CLIP	23592263
MIRT477212	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT477211	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT477210	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT477209	hsa-miR-5194	PAR-CLIP	23592263
MIRT477208	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT477207	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT477206	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT477205	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT253410	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT253411	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT253418	hsa-miR-449b-5p	PAR-CLIP	21572407
MIRT253412	hsa-miR-34a-5p	PAR-CLIP	21572407
MIRT253414	hsa-miR-34c-5p	PAR-CLIP	21572407
MIRT253415	hsa-miR-449a	PAR-CLIP	21572407
MIRT253410	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT253411	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT253413	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT253416	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT349239	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT349235	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT349236	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT558061	hsa-miR-4716-3p	PAR-CLIP	21572407
MIRT558060	hsa-miR-6794-5p	PAR-CLIP	21572407
MIRT558058	hsa-miR-6805-5p	PAR-CLIP	21572407
MIRT558059	hsa-miR-6732-5p	PAR-CLIP	21572407
MIRT295049	hsa-miR-4280	PAR-CLIP	21572407
MIRT253417	hsa-miR-648	PAR-CLIP	21572407
MIRT253426	hsa-miR-4698	PAR-CLIP	21572407
MIRT349241	hsa-miR-4514	PAR-CLIP	21572407
MIRT349242	hsa-miR-4692	PAR-CLIP	21572407
MIRT253423	hsa-miR-4302	PAR-CLIP	21572407
MIRT253430	hsa-miR-7112-5p	PAR-CLIP	21572407
MIRT253424	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT253420	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT253421	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT253422	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT253419	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT253428	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT558057	hsa-miR-1908-5p	PAR-CLIP	21572407
MIRT558056	hsa-miR-663a	PAR-CLIP	21572407
MIRT558055	hsa-miR-6787-5p	PAR-CLIP	21572407
MIRT558054	hsa-miR-1268a	PAR-CLIP	21572407
MIRT558053	hsa-miR-1268b	PAR-CLIP	21572407
MIRT558052	hsa-miR-1237-5p	PAR-CLIP	21572407
MIRT558051	hsa-miR-4488	PAR-CLIP	21572407
MIRT558050	hsa-miR-4697-5p	PAR-CLIP	21572407
MIRT295048	hsa-miR-4278	PAR-CLIP	21572407
MIRT253427	hsa-miR-548aw	PAR-CLIP	21572407
MIRT295047	hsa-miR-135b-3p	PAR-CLIP	21572407
MIRT477216	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT477214	hsa-miR-4459	PAR-CLIP	23592263
MIRT477215	hsa-miR-665	PAR-CLIP	23592263
MIRT477213	hsa-miR-6089	PAR-CLIP	23592263
MIRT477212	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT477211	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT477210	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT477209	hsa-miR-5194	PAR-CLIP	23592263
MIRT477208	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT477207	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT477206	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT477205	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT972338	hsa-miR-150	CLIP-seq
MIRT972339	hsa-miR-299-3p	CLIP-seq
MIRT972340	hsa-miR-3151	CLIP-seq
MIRT972341	hsa-miR-3919	CLIP-seq
MIRT972342	hsa-miR-4447	CLIP-seq
MIRT972343	hsa-miR-4472	CLIP-seq
MIRT972344	hsa-miR-4713-5p	CLIP-seq
MIRT972345	hsa-miR-491-5p	CLIP-seq
MIRT972346	hsa-miR-532-3p	CLIP-seq
MIRT972347	hsa-miR-576-3p	CLIP-seq
MIRT1556324	hsa-miR-4532	CLIP-seq
MIRT1988049	hsa-miR-149	CLIP-seq
MIRT1988050	hsa-miR-661	CLIP-seq
MIRT2222530	hsa-miR-1908	CLIP-seq
MIRT2222531	hsa-miR-1910	CLIP-seq
MIRT2222532	hsa-miR-19a	CLIP-seq
MIRT2222533	hsa-miR-19b	CLIP-seq
MIRT2222534	hsa-miR-2355-5p	CLIP-seq
MIRT2222535	hsa-miR-2682	CLIP-seq
MIRT972340	hsa-miR-3151	CLIP-seq
MIRT2222536	hsa-miR-34a	CLIP-seq
MIRT2222537	hsa-miR-3652	CLIP-seq
MIRT972341	hsa-miR-3919	CLIP-seq
MIRT2222538	hsa-miR-4261	CLIP-seq
MIRT2222539	hsa-miR-4264	CLIP-seq
MIRT2222540	hsa-miR-4283	CLIP-seq
MIRT2222541	hsa-miR-4430	CLIP-seq
MIRT2222542	hsa-miR-4489	CLIP-seq
MIRT2222543	hsa-miR-4492	CLIP-seq
MIRT2222544	hsa-miR-4498	CLIP-seq
MIRT2222545	hsa-miR-449b	CLIP-seq
MIRT2222546	hsa-miR-449c	CLIP-seq
MIRT2222547	hsa-miR-455-3p	CLIP-seq
MIRT2222548	hsa-miR-4643	CLIP-seq
MIRT2222549	hsa-miR-522	CLIP-seq
MIRT2222550	hsa-miR-544b	CLIP-seq
MIRT2222551	hsa-miR-663	CLIP-seq
MIRT2222552	hsa-miR-762	CLIP-seq
MIRT2222553	hsa-miR-875-3p	CLIP-seq
MIRT972340	hsa-miR-3151	CLIP-seq
MIRT972342	hsa-miR-4447	CLIP-seq
MIRT972343	hsa-miR-4472	CLIP-seq
MIRT2387576	hsa-miR-486-3p	CLIP-seq
MIRT972345	hsa-miR-491-5p	CLIP-seq
MIRT2448980	hsa-miR-1252	CLIP-seq
MIRT2448981	hsa-miR-4722-3p	CLIP-seq
MIRT2448982	hsa-miR-4755-3p	CLIP-seq
MIRT2448983	hsa-miR-4763-5p	CLIP-seq
MIRT2448984	hsa-miR-596	CLIP-seq
MIRT2448985	hsa-miR-671-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IDA	17646400
GO:0005096	Function	GTPase activator activity	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 19060904, 32296183
GO:0031267	Function	Small GTPase binding	IEA
GO:0031267	Function	Small GTPase binding	IPI	17646400
GO:0043547	Process	Positive regulation of GTPase activity	IDA	17646400
GO:1902018	Process	Negative regulation of cilium assembly	IMP	17646400

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96CN4
• Protein name: EVI5-like protein (Ecotropic viral integration site 5-like protein)
• Protein function: Functions as a GTPase-activating protein (GAP) with a broad specificity.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00566	RabGAP-TBC	118 → 320	Rab-GTPase-TBC domain	Family

• Sequence:

  MASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNG
  SRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHF
  RAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLF
  NVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELG
  LCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEG
  LEIVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKM
  KRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKGQVTRAQEAEENYVIKRELA
  VVRQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALRE
  MQDKVLDMEKRNSSLPDENNVAQLQEELKALKVREGQAVASTRELKLQLQELSDTWQAHL
  ARGGRWKESPRKLVVGELQDELMSVRLREAQALAEGRELRQRVVELETQDHIHRNLLNRV
  EAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEM
  RQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKAEVRLLKGPPPFEDPLAFDG
  LSLARHLDEDSLPSSDEELLGVGVGAALQDALYPLSPRDARFFRRLERPAKDSEGSSDSD
  ADELAAPYSQGLDN

• Sequence length: 794

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations