OSBPL11 (oxysterol binding protein like 11)

Gene

• Entrez ID: 114885
• Gene name: Oxysterol binding protein like 11
• Gene symbol: OSBPL11
• Synonyms (NCBI Gene): ORP-11, ORP11, OSBP12, TCCCIA00292
• Chromosome: 3
• Chromosome location: 3q21.2
• Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like stero

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019404	hsa-miR-148b-3p	Microarray	17612493
MIRT025790	hsa-miR-7-5p	Microarray	17612493
MIRT040400	hsa-miR-615-3p	CLASH	23622248
MIRT025790	hsa-miR-7-5p	Luciferase reporter assay, Western blotting, qRT-PCR	35012554
MIRT1205988	hsa-miR-1185	CLIP-seq
MIRT1205989	hsa-miR-1202	CLIP-seq
MIRT1205990	hsa-miR-1224-5p	CLIP-seq
MIRT1205991	hsa-miR-1243	CLIP-seq
MIRT1205992	hsa-miR-1251	CLIP-seq
MIRT1205993	hsa-miR-1253	CLIP-seq
MIRT1205994	hsa-miR-1261	CLIP-seq
MIRT1205995	hsa-miR-1279	CLIP-seq
MIRT1205996	hsa-miR-1283	CLIP-seq
MIRT1205997	hsa-miR-1290	CLIP-seq
MIRT1205998	hsa-miR-1297	CLIP-seq
MIRT1205999	hsa-miR-1304	CLIP-seq
MIRT1206000	hsa-miR-1305	CLIP-seq
MIRT1206001	hsa-miR-130a	CLIP-seq
MIRT1206002	hsa-miR-130b	CLIP-seq
MIRT1206003	hsa-miR-1324	CLIP-seq
MIRT1206004	hsa-miR-133a	CLIP-seq
MIRT1206005	hsa-miR-133b	CLIP-seq
MIRT1206006	hsa-miR-136	CLIP-seq
MIRT1206007	hsa-miR-141	CLIP-seq
MIRT1206008	hsa-miR-147	CLIP-seq
MIRT1206009	hsa-miR-148a	CLIP-seq
MIRT1206010	hsa-miR-148b	CLIP-seq
MIRT1206011	hsa-miR-152	CLIP-seq
MIRT1206012	hsa-miR-181a	CLIP-seq
MIRT1206013	hsa-miR-181b	CLIP-seq
MIRT1206014	hsa-miR-181c	CLIP-seq
MIRT1206015	hsa-miR-181d	CLIP-seq
MIRT1206016	hsa-miR-1913	CLIP-seq
MIRT1206017	hsa-miR-1914	CLIP-seq
MIRT1206018	hsa-miR-200a	CLIP-seq
MIRT1206019	hsa-miR-200b	CLIP-seq
MIRT1206020	hsa-miR-200c	CLIP-seq
MIRT1206021	hsa-miR-2054	CLIP-seq
MIRT1206022	hsa-miR-2117	CLIP-seq
MIRT1206023	hsa-miR-216a	CLIP-seq
MIRT1206024	hsa-miR-26a	CLIP-seq
MIRT1206025	hsa-miR-26b	CLIP-seq
MIRT1206026	hsa-miR-27a	CLIP-seq
MIRT1206027	hsa-miR-27b	CLIP-seq
MIRT1206028	hsa-miR-2909	CLIP-seq
MIRT1206029	hsa-miR-301a	CLIP-seq
MIRT1206030	hsa-miR-301b	CLIP-seq
MIRT1206031	hsa-miR-302f	CLIP-seq
MIRT1206032	hsa-miR-30a	CLIP-seq
MIRT1206033	hsa-miR-30b	CLIP-seq
MIRT1206034	hsa-miR-30c	CLIP-seq
MIRT1206035	hsa-miR-30d	CLIP-seq
MIRT1206036	hsa-miR-30e	CLIP-seq
MIRT1206037	hsa-miR-3120-3p	CLIP-seq
MIRT1206038	hsa-miR-3157-3p	CLIP-seq
MIRT1206039	hsa-miR-3165	CLIP-seq
MIRT1206040	hsa-miR-3192	CLIP-seq
MIRT1206041	hsa-miR-3194-5p	CLIP-seq
MIRT1206042	hsa-miR-3201	CLIP-seq
MIRT1206043	hsa-miR-324-3p	CLIP-seq
MIRT1206044	hsa-miR-325	CLIP-seq
MIRT1206045	hsa-miR-3605-5p	CLIP-seq
MIRT1206046	hsa-miR-3654	CLIP-seq
MIRT1206047	hsa-miR-3662	CLIP-seq
MIRT1206048	hsa-miR-3666	CLIP-seq
MIRT1206049	hsa-miR-3679-5p	CLIP-seq
MIRT1206050	hsa-miR-3689a-3p	CLIP-seq
MIRT1206051	hsa-miR-3689c	CLIP-seq
MIRT1206052	hsa-miR-369-3p	CLIP-seq
MIRT1206053	hsa-miR-375	CLIP-seq
MIRT1206054	hsa-miR-3915	CLIP-seq
MIRT1206055	hsa-miR-3919	CLIP-seq
MIRT1206056	hsa-miR-3972	CLIP-seq
MIRT1206057	hsa-miR-409-3p	CLIP-seq
MIRT1206058	hsa-miR-4257	CLIP-seq
MIRT1206059	hsa-miR-4262	CLIP-seq
MIRT1206060	hsa-miR-4269	CLIP-seq
MIRT1206061	hsa-miR-4273	CLIP-seq
MIRT1206062	hsa-miR-4276	CLIP-seq
MIRT1206063	hsa-miR-4289	CLIP-seq
MIRT1206064	hsa-miR-429	CLIP-seq
MIRT1206065	hsa-miR-4295	CLIP-seq
MIRT1206066	hsa-miR-4311	CLIP-seq
MIRT1206067	hsa-miR-4314	CLIP-seq
MIRT1206068	hsa-miR-4326	CLIP-seq
MIRT1206069	hsa-miR-4422	CLIP-seq
MIRT1206070	hsa-miR-4446-5p	CLIP-seq
MIRT1206071	hsa-miR-4465	CLIP-seq
MIRT1206072	hsa-miR-4514	CLIP-seq
MIRT1206073	hsa-miR-454	CLIP-seq
MIRT1206074	hsa-miR-4646-5p	CLIP-seq
MIRT1206075	hsa-miR-4668-3p	CLIP-seq
MIRT1206076	hsa-miR-4677-5p	CLIP-seq
MIRT1206077	hsa-miR-4684-5p	CLIP-seq
MIRT1206078	hsa-miR-4686	CLIP-seq
MIRT1206079	hsa-miR-4689	CLIP-seq
MIRT1206080	hsa-miR-4692	CLIP-seq
MIRT1206081	hsa-miR-4709-3p	CLIP-seq
MIRT1206082	hsa-miR-4724-5p	CLIP-seq
MIRT1206083	hsa-miR-4728-5p	CLIP-seq
MIRT1206084	hsa-miR-4742-5p	CLIP-seq
MIRT1206085	hsa-miR-4749-3p	CLIP-seq
MIRT1206086	hsa-miR-4766-5p	CLIP-seq
MIRT1206087	hsa-miR-4789-3p	CLIP-seq
MIRT1206088	hsa-miR-4791	CLIP-seq
MIRT1206089	hsa-miR-4795-3p	CLIP-seq
MIRT1206090	hsa-miR-498	CLIP-seq
MIRT1206091	hsa-miR-5096	CLIP-seq
MIRT1206092	hsa-miR-513a-5p	CLIP-seq
MIRT1206093	hsa-miR-513c	CLIP-seq
MIRT1206094	hsa-miR-514b-5p	CLIP-seq
MIRT1206095	hsa-miR-520d-5p	CLIP-seq
MIRT1206096	hsa-miR-524-5p	CLIP-seq
MIRT1206097	hsa-miR-548a-3p	CLIP-seq
MIRT1206098	hsa-miR-548b-3p	CLIP-seq
MIRT1206099	hsa-miR-548e	CLIP-seq
MIRT1206100	hsa-miR-548f	CLIP-seq
MIRT1206101	hsa-miR-548t	CLIP-seq
MIRT1206102	hsa-miR-579	CLIP-seq
MIRT1206103	hsa-miR-593	CLIP-seq
MIRT1206104	hsa-miR-622	CLIP-seq
MIRT1206105	hsa-miR-656	CLIP-seq
MIRT1206106	hsa-miR-668	CLIP-seq
MIRT1206107	hsa-miR-873	CLIP-seq
MIRT1206047	hsa-miR-3662	CLIP-seq
MIRT1206090	hsa-miR-498	CLIP-seq
MIRT1206001	hsa-miR-130a	CLIP-seq
MIRT1206002	hsa-miR-130b	CLIP-seq
MIRT1206009	hsa-miR-148a	CLIP-seq
MIRT1206010	hsa-miR-148b	CLIP-seq
MIRT1206011	hsa-miR-152	CLIP-seq
MIRT2059354	hsa-miR-29a	CLIP-seq
MIRT2059355	hsa-miR-29b	CLIP-seq
MIRT2059356	hsa-miR-29c	CLIP-seq
MIRT1206029	hsa-miR-301a	CLIP-seq
MIRT1206030	hsa-miR-301b	CLIP-seq
MIRT2059357	hsa-miR-3153	CLIP-seq
MIRT1206039	hsa-miR-3165	CLIP-seq
MIRT2059358	hsa-miR-3663-3p	CLIP-seq
MIRT1206048	hsa-miR-3666	CLIP-seq
MIRT1206058	hsa-miR-4257	CLIP-seq
MIRT1206065	hsa-miR-4295	CLIP-seq
MIRT1206067	hsa-miR-4314	CLIP-seq
MIRT2059359	hsa-miR-4327	CLIP-seq
MIRT2059360	hsa-miR-4436b-5p	CLIP-seq
MIRT2059361	hsa-miR-4453	CLIP-seq
MIRT2059362	hsa-miR-4538	CLIP-seq
MIRT1206073	hsa-miR-454	CLIP-seq
MIRT2059363	hsa-miR-4668-5p	CLIP-seq
MIRT2059364	hsa-miR-4691-3p	CLIP-seq
MIRT1206086	hsa-miR-4766-5p	CLIP-seq
MIRT1206091	hsa-miR-5096	CLIP-seq
MIRT2059365	hsa-miR-548ag	CLIP-seq
MIRT2059366	hsa-miR-548ai	CLIP-seq
MIRT2059367	hsa-miR-635	CLIP-seq
MIRT1206106	hsa-miR-668	CLIP-seq
MIRT2059368	hsa-miR-767-5p	CLIP-seq
MIRT2059369	hsa-miR-802	CLIP-seq
MIRT1206107	hsa-miR-873	CLIP-seq
MIRT2287712	hsa-miR-124	CLIP-seq
MIRT1205994	hsa-miR-1261	CLIP-seq
MIRT2287713	hsa-miR-1272	CLIP-seq
MIRT1205996	hsa-miR-1283	CLIP-seq
MIRT1205997	hsa-miR-1290	CLIP-seq
MIRT1206003	hsa-miR-1324	CLIP-seq
MIRT1206004	hsa-miR-133a	CLIP-seq
MIRT1206005	hsa-miR-133b	CLIP-seq
MIRT1206006	hsa-miR-136	CLIP-seq
MIRT1206009	hsa-miR-148a	CLIP-seq
MIRT1206010	hsa-miR-148b	CLIP-seq
MIRT1206011	hsa-miR-152	CLIP-seq
MIRT1206012	hsa-miR-181a	CLIP-seq
MIRT1206013	hsa-miR-181b	CLIP-seq
MIRT1206014	hsa-miR-181c	CLIP-seq
MIRT1206015	hsa-miR-181d	CLIP-seq
MIRT1206026	hsa-miR-27a	CLIP-seq
MIRT1206027	hsa-miR-27b	CLIP-seq
MIRT1206028	hsa-miR-2909	CLIP-seq
MIRT2059354	hsa-miR-29a	CLIP-seq
MIRT2059355	hsa-miR-29b	CLIP-seq
MIRT2059356	hsa-miR-29c	CLIP-seq
MIRT1206032	hsa-miR-30a	CLIP-seq
MIRT1206033	hsa-miR-30b	CLIP-seq
MIRT1206034	hsa-miR-30c	CLIP-seq
MIRT1206035	hsa-miR-30d	CLIP-seq
MIRT1206036	hsa-miR-30e	CLIP-seq
MIRT1206037	hsa-miR-3120-3p	CLIP-seq
MIRT2287714	hsa-miR-3150a-5p	CLIP-seq
MIRT2287715	hsa-miR-3150b-5p	CLIP-seq
MIRT2059357	hsa-miR-3153	CLIP-seq
MIRT1206039	hsa-miR-3165	CLIP-seq
MIRT1206040	hsa-miR-3192	CLIP-seq
MIRT2059358	hsa-miR-3663-3p	CLIP-seq
MIRT1206050	hsa-miR-3689a-3p	CLIP-seq
MIRT1206051	hsa-miR-3689c	CLIP-seq
MIRT2287716	hsa-miR-3714	CLIP-seq
MIRT2287717	hsa-miR-3907	CLIP-seq
MIRT2287718	hsa-miR-3910	CLIP-seq
MIRT1206055	hsa-miR-3919	CLIP-seq
MIRT1206058	hsa-miR-4257	CLIP-seq
MIRT1206059	hsa-miR-4262	CLIP-seq
MIRT1206062	hsa-miR-4276	CLIP-seq
MIRT2287719	hsa-miR-431	CLIP-seq
MIRT1206067	hsa-miR-4314	CLIP-seq
MIRT1206068	hsa-miR-4326	CLIP-seq
MIRT2059359	hsa-miR-4327	CLIP-seq
MIRT2059360	hsa-miR-4436b-5p	CLIP-seq
MIRT2287720	hsa-miR-4444	CLIP-seq
MIRT2287721	hsa-miR-4450	CLIP-seq
MIRT2059361	hsa-miR-4453	CLIP-seq
MIRT2059362	hsa-miR-4538	CLIP-seq
MIRT1206074	hsa-miR-4646-5p	CLIP-seq
MIRT2059363	hsa-miR-4668-5p	CLIP-seq
MIRT1206083	hsa-miR-4728-5p	CLIP-seq
MIRT1206086	hsa-miR-4766-5p	CLIP-seq
MIRT2287722	hsa-miR-506	CLIP-seq
MIRT1206091	hsa-miR-5096	CLIP-seq
MIRT1206092	hsa-miR-513a-5p	CLIP-seq
MIRT1206095	hsa-miR-520d-5p	CLIP-seq
MIRT1206096	hsa-miR-524-5p	CLIP-seq
MIRT2287723	hsa-miR-532-5p	CLIP-seq
MIRT2287724	hsa-miR-545	CLIP-seq
MIRT2059365	hsa-miR-548ag	CLIP-seq
MIRT2059366	hsa-miR-548ai	CLIP-seq
MIRT2287725	hsa-miR-562	CLIP-seq
MIRT2287726	hsa-miR-584	CLIP-seq
MIRT1206104	hsa-miR-622	CLIP-seq
MIRT2059367	hsa-miR-635	CLIP-seq
MIRT2059368	hsa-miR-767-5p	CLIP-seq
MIRT2059369	hsa-miR-802	CLIP-seq
MIRT2287727	hsa-miR-9	CLIP-seq
MIRT2287717	hsa-miR-3907	CLIP-seq
MIRT2585682	hsa-miR-1178	CLIP-seq
MIRT2287712	hsa-miR-124	CLIP-seq
MIRT1206004	hsa-miR-133a	CLIP-seq
MIRT1206005	hsa-miR-133b	CLIP-seq
MIRT2585683	hsa-miR-137	CLIP-seq
MIRT2059354	hsa-miR-29a	CLIP-seq
MIRT2059355	hsa-miR-29b	CLIP-seq
MIRT2059356	hsa-miR-29c	CLIP-seq
MIRT2585684	hsa-miR-3074-3p	CLIP-seq
MIRT2059357	hsa-miR-3153	CLIP-seq
MIRT2585685	hsa-miR-329	CLIP-seq
MIRT2585686	hsa-miR-361-5p	CLIP-seq
MIRT2585687	hsa-miR-362-3p	CLIP-seq
MIRT2585688	hsa-miR-3658	CLIP-seq
MIRT2059358	hsa-miR-3663-3p	CLIP-seq
MIRT2287716	hsa-miR-3714	CLIP-seq
MIRT2287718	hsa-miR-3910	CLIP-seq
MIRT2585689	hsa-miR-3941	CLIP-seq
MIRT2287719	hsa-miR-431	CLIP-seq
MIRT2059359	hsa-miR-4327	CLIP-seq
MIRT2585690	hsa-miR-4426	CLIP-seq
MIRT2059361	hsa-miR-4453	CLIP-seq
MIRT2059362	hsa-miR-4538	CLIP-seq
MIRT2585691	hsa-miR-4647	CLIP-seq
MIRT2585692	hsa-miR-466	CLIP-seq
MIRT2585693	hsa-miR-4662b	CLIP-seq
MIRT2059363	hsa-miR-4668-5p	CLIP-seq
MIRT2585694	hsa-miR-4672	CLIP-seq
MIRT2059364	hsa-miR-4691-3p	CLIP-seq
MIRT2585695	hsa-miR-4717-3p	CLIP-seq
MIRT2585696	hsa-miR-4797-5p	CLIP-seq
MIRT2585697	hsa-miR-499-3p	CLIP-seq
MIRT2585698	hsa-miR-499a-3p	CLIP-seq
MIRT2287722	hsa-miR-506	CLIP-seq
MIRT2585699	hsa-miR-509-3p	CLIP-seq
MIRT2059365	hsa-miR-548ag	CLIP-seq
MIRT2059366	hsa-miR-548ai	CLIP-seq
MIRT2585700	hsa-miR-567	CLIP-seq
MIRT2585701	hsa-miR-603	CLIP-seq
MIRT2059367	hsa-miR-635	CLIP-seq
MIRT2585702	hsa-miR-7	CLIP-seq
MIRT2059368	hsa-miR-767-5p	CLIP-seq
MIRT2059369	hsa-miR-802	CLIP-seq
MIRT2585703	hsa-miR-892a	CLIP-seq
MIRT2287727	hsa-miR-9	CLIP-seq
MIRT2585682	hsa-miR-1178	CLIP-seq
MIRT2287712	hsa-miR-124	CLIP-seq
MIRT1206004	hsa-miR-133a	CLIP-seq
MIRT1206005	hsa-miR-133b	CLIP-seq
MIRT2585683	hsa-miR-137	CLIP-seq
MIRT2059354	hsa-miR-29a	CLIP-seq
MIRT2059355	hsa-miR-29b	CLIP-seq
MIRT2059356	hsa-miR-29c	CLIP-seq
MIRT2585684	hsa-miR-3074-3p	CLIP-seq
MIRT2059357	hsa-miR-3153	CLIP-seq
MIRT2585685	hsa-miR-329	CLIP-seq
MIRT2585686	hsa-miR-361-5p	CLIP-seq
MIRT2585687	hsa-miR-362-3p	CLIP-seq
MIRT2585688	hsa-miR-3658	CLIP-seq
MIRT2059358	hsa-miR-3663-3p	CLIP-seq
MIRT2287716	hsa-miR-3714	CLIP-seq
MIRT2287718	hsa-miR-3910	CLIP-seq
MIRT2585689	hsa-miR-3941	CLIP-seq
MIRT2287719	hsa-miR-431	CLIP-seq
MIRT2059359	hsa-miR-4327	CLIP-seq
MIRT2585690	hsa-miR-4426	CLIP-seq
MIRT2059361	hsa-miR-4453	CLIP-seq
MIRT2059362	hsa-miR-4538	CLIP-seq
MIRT2585691	hsa-miR-4647	CLIP-seq
MIRT2585692	hsa-miR-466	CLIP-seq
MIRT2585693	hsa-miR-4662b	CLIP-seq
MIRT2059363	hsa-miR-4668-5p	CLIP-seq
MIRT2585694	hsa-miR-4672	CLIP-seq
MIRT2059364	hsa-miR-4691-3p	CLIP-seq
MIRT2585695	hsa-miR-4717-3p	CLIP-seq
MIRT2585696	hsa-miR-4797-5p	CLIP-seq
MIRT2585697	hsa-miR-499-3p	CLIP-seq
MIRT2585698	hsa-miR-499a-3p	CLIP-seq
MIRT2287722	hsa-miR-506	CLIP-seq
MIRT2585699	hsa-miR-509-3p	CLIP-seq
MIRT2059365	hsa-miR-548ag	CLIP-seq
MIRT2059366	hsa-miR-548ai	CLIP-seq
MIRT2585700	hsa-miR-567	CLIP-seq
MIRT2585701	hsa-miR-603	CLIP-seq
MIRT2059367	hsa-miR-635	CLIP-seq
MIRT2585702	hsa-miR-7	CLIP-seq
MIRT2059368	hsa-miR-767-5p	CLIP-seq
MIRT2059369	hsa-miR-802	CLIP-seq
MIRT2585703	hsa-miR-892a	CLIP-seq
MIRT2287727	hsa-miR-9	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19615732, 20599956, 22906437, 35271311
GO:0005654	Component	Nucleoplasm	IDA
GO:0005768	Component	Endosome	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	IBA
GO:0006869	Process	Lipid transport	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0032934	Function	Sterol binding	IBA
GO:0045444	Process	Fat cell differentiation	IMP	23028956
GO:0070328	Process	Triglyceride homeostasis	IMP	23028956

Other IDs

• MIM: 606739
• HGNC: 16397
• e!Ensembl: ENSG00000144909

Protein

• UniProt ID: Q9BXB4
• Protein name: Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)
• Protein function: Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193). Interacts with OSBPL9
• PDB: 2D9X
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00169	PH	60 → 155	PH domain	Domain
  PF01237	Oxysterol_BP	372 → 738	Oxysterol-binding protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present
• Sequence:

  MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMEN
  VYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDS
  HTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSN
  SPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIEC
  LPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKI
  SLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDL
  GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGAT
  AEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG
  VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL
  GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASI
  TFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTK
  KRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKT
  KYFIKEGDGWVYHKPLWKIIPTTQPAE

• Sequence length: 747

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ASTROCYTOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	31173207, 36918840	Associate	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	19325544		★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	19325544	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	19325544	Associate	★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	Pubtator	19325544	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	31173207		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Mandibulofacial Dysostosis	Mandibulofacial dysostosis	Pubtator	28051070	Associate	★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	19325544	Stimulate	★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	19325544	Associate	★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	19325544		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	28051070	Associate	★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	19325544		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	19325544	Associate	★☆☆☆☆ Found in Text Mining only