Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	114294
Gene name	Lactamase beta
Gene symbol	LACTB
Synonyms (NCBI Gene)	G24MRPL56
Chromosome	15
Chromosome location	15q22.2
Summary	This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004998	hsa-miR-125b-5p	Microarray	17891175
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	22927820
MIRT643854	hsa-miR-764	HITS-CLIP	22927820
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	22927820
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	22927820
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	22927820
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	22927820
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	22927820
MIRT662109	hsa-miR-4635	HITS-CLIP	22927820
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	22927820
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	22927820
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	22927820
MIRT643848	hsa-miR-4297	HITS-CLIP	22927820
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	22927820
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	22927820
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	22927820
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	22927820
MIRT643847	hsa-miR-640	HITS-CLIP	22927820
MIRT683726	hsa-miR-4418	HITS-CLIP	23313552
MIRT683725	hsa-miR-509-3-5p	HITS-CLIP	23313552
MIRT683724	hsa-miR-509-5p	HITS-CLIP	23313552
MIRT683723	hsa-miR-217	HITS-CLIP	23313552
MIRT683722	hsa-miR-6807-3p	HITS-CLIP	23313552
MIRT683721	hsa-miR-1306-5p	HITS-CLIP	23313552
MIRT683720	hsa-miR-891b	HITS-CLIP	23313552
MIRT662102	hsa-miR-498	HITS-CLIP	23313552
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679042	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT679041	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT679040	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT679039	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT679038	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT679037	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT679036	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662102	hsa-miR-498	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT662109	hsa-miR-4635	HITS-CLIP	23824327
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662111	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT662110	hsa-miR-520h	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT662109	hsa-miR-4635	HITS-CLIP	23824327
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662102	hsa-miR-498	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT004998	hsa-miR-125b-5p	Luciferase reporter assayWestern blot	26603571
MIRT004998	hsa-miR-125b-5p	Luciferase reporter assayWestern blot	26603571
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	22927820
MIRT643854	hsa-miR-764	HITS-CLIP	22927820
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	22927820
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	22927820
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	22927820
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	22927820
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	22927820
MIRT662109	hsa-miR-4635	HITS-CLIP	22927820
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	22927820
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	22927820
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	22927820
MIRT643848	hsa-miR-4297	HITS-CLIP	22927820
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	22927820
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	22927820
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	22927820
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	22927820
MIRT643847	hsa-miR-640	HITS-CLIP	22927820
MIRT683726	hsa-miR-4418	HITS-CLIP	23313552
MIRT683725	hsa-miR-509-3-5p	HITS-CLIP	23313552
MIRT683724	hsa-miR-509-5p	HITS-CLIP	23313552
MIRT683723	hsa-miR-217	HITS-CLIP	23313552
MIRT683722	hsa-miR-6807-3p	HITS-CLIP	23313552
MIRT683721	hsa-miR-1306-5p	HITS-CLIP	23313552
MIRT683720	hsa-miR-891b	HITS-CLIP	23313552
MIRT662102	hsa-miR-498	HITS-CLIP	23313552
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679042	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT679041	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT679040	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT679039	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT679038	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT679037	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT679036	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662102	hsa-miR-498	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT662109	hsa-miR-4635	HITS-CLIP	23824327
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662111	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT662110	hsa-miR-520h	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT662109	hsa-miR-4635	HITS-CLIP	23824327
MIRT662108	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT662107	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT662106	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT662105	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT662104	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT662103	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT662102	hsa-miR-498	HITS-CLIP	23824327
MIRT643855	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT643854	hsa-miR-764	HITS-CLIP	23824327
MIRT643853	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT643852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT643851	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT643850	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT643848	hsa-miR-4297	HITS-CLIP	23824327
MIRT643849	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT643847	hsa-miR-640	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT631218	hsa-miR-4279	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT618130	hsa-miR-1471	HITS-CLIP	23824327
MIRT618129	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT618128	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT618127	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT618126	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT618125	hsa-miR-1976	HITS-CLIP	23824327
MIRT618124	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT618123	hsa-miR-3652	HITS-CLIP	23824327
MIRT618122	hsa-miR-4430	HITS-CLIP	23824327
MIRT618121	hsa-miR-4505	HITS-CLIP	23824327
MIRT618120	hsa-miR-5787	HITS-CLIP	23824327
MIRT618119	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT1103048	hsa-miR-2052	CLIP-seq
MIRT1103049	hsa-miR-3613-3p	CLIP-seq
MIRT1103050	hsa-miR-3671	CLIP-seq
MIRT1103051	hsa-miR-409-3p	CLIP-seq
MIRT1103052	hsa-miR-4307	CLIP-seq
MIRT1103053	hsa-miR-548c-3p	CLIP-seq
MIRT1103054	hsa-miR-607	CLIP-seq
MIRT1103055	hsa-miR-935	CLIP-seq
MIRT2028177	hsa-miR-4503	CLIP-seq
MIRT2028178	hsa-miR-520d-5p	CLIP-seq
MIRT2028179	hsa-miR-524-5p	CLIP-seq
MIRT2028180	hsa-miR-885-5p	CLIP-seq

Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28514442, 33961781
GO:0005739	Component	Mitochondrion	HDA	20833797
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	28329758
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006508	Process	Proteolysis	IBA
GO:0006508	Process	Proteolysis	IDA	28329758
GO:0006508	Process	Proteolysis	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0008233	Function	Peptidase activity	IBA
GO:0008233	Function	Peptidase activity	IDA	28329758
GO:0008233	Function	Peptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019216	Process	Regulation of lipid metabolic process	IBA
GO:0019216	Process	Regulation of lipid metabolic process	IDA	28329758
GO:0042802	Function	Identical protein binding	IEA

MIM	HGNC	e!Ensembl
608440	16468	ENSG00000103642

P83111

Protein name

Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)

Protein function

Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (

PDB

7ULW , 7V1Y , 7V1Z , 7V21

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00144	Beta-lactamase	111 → 253	Beta-lactamase	Domain
PF00144	Beta-lactamase	277 → 538	Beta-lactamase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed predominantly in skeletal muscle. {ECO:0000269|PubMed:11707067}.

Sequence

MYRLMSAVTARAAAPGGLASSCGRRGVHQRAGLPPLGHGWVGGLGLGLGLALGVKLAGGL
RGAAPAQSPAAPDPEASPLAEPPQEQSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKD
EVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEA
GKLDLDIPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALK
MMKENVAFEQEKEGKSNEKNDFTKFKTEQENEAKCRNSKPGKKKNDFEQGELYLREKFEN
SIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGCKYLDYMQKIFHDLDMLTTV
QEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQV
GLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVERKQTYGSCRKQR
HYASHTGGAVGASSVLLVLPEELDTETINNKVPPRGIIVSIICNMQSVGLNSTALKIALE
FDKDRSD

Sequence length

547

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Abnormality of neuronal migration	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DENTAL CARIES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUTROPENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (18)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	34937778	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	29790671		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	28835318, 36088805	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	36282364	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	38176415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	36375842	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29899406		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	36088805	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	28835318		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	28835318	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	36088805	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	28835318, 29790671		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29790671		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28329758, 29790671, 29899406		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	CTD_human_DG	18344982		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	36375842	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	33507917	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	38149985, 40603395	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

LACTB (lactamase beta)