Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	113402
Gene name	SFT2 domain containing 1
Gene symbol	SFT2D1
Synonyms (NCBI Gene)	C6orf83pRGR1
Chromosome	6
Chromosome location	6q27

142

Show/Hide all (142)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016674	hsa-miR-425-5p	Sequencing	20371350
MIRT046559	hsa-let-7g-5p	CLASH	23622248
MIRT046469	hsa-miR-15b-5p	CLASH	23622248
MIRT1341991	hsa-miR-122	CLIP-seq
MIRT1341992	hsa-miR-1343	CLIP-seq
MIRT1341993	hsa-miR-197	CLIP-seq
MIRT1341994	hsa-miR-2110	CLIP-seq
MIRT1341995	hsa-miR-223	CLIP-seq
MIRT1341996	hsa-miR-3115	CLIP-seq
MIRT1341997	hsa-miR-3659	CLIP-seq
MIRT1341998	hsa-miR-3675-5p	CLIP-seq
MIRT1341999	hsa-miR-3690	CLIP-seq
MIRT1342000	hsa-miR-412	CLIP-seq
MIRT1342001	hsa-miR-4254	CLIP-seq
MIRT1342002	hsa-miR-4271	CLIP-seq
MIRT1342003	hsa-miR-4326	CLIP-seq
MIRT1342004	hsa-miR-4668-5p	CLIP-seq
MIRT1342005	hsa-miR-4725-3p	CLIP-seq
MIRT2101220	hsa-miR-300	CLIP-seq
MIRT2101221	hsa-miR-3662	CLIP-seq
MIRT2101222	hsa-miR-381	CLIP-seq
MIRT2101223	hsa-miR-4666-3p	CLIP-seq
MIRT2101224	hsa-miR-4698	CLIP-seq
MIRT2101225	hsa-miR-4703-3p	CLIP-seq
MIRT2325595	hsa-miR-1297	CLIP-seq
MIRT2325596	hsa-miR-181a	CLIP-seq
MIRT2325597	hsa-miR-181b	CLIP-seq
MIRT2325598	hsa-miR-181c	CLIP-seq
MIRT2325599	hsa-miR-181d	CLIP-seq
MIRT2325600	hsa-miR-1911	CLIP-seq
MIRT2325601	hsa-miR-26a	CLIP-seq
MIRT2325602	hsa-miR-26b	CLIP-seq
MIRT2101220	hsa-miR-300	CLIP-seq
MIRT2325603	hsa-miR-302a	CLIP-seq
MIRT2325604	hsa-miR-302b	CLIP-seq
MIRT2325605	hsa-miR-302c	CLIP-seq
MIRT2325606	hsa-miR-302d	CLIP-seq
MIRT2325607	hsa-miR-302e	CLIP-seq
MIRT2101221	hsa-miR-3662	CLIP-seq
MIRT2325608	hsa-miR-3672	CLIP-seq
MIRT2325609	hsa-miR-372	CLIP-seq
MIRT2325610	hsa-miR-373	CLIP-seq
MIRT2101222	hsa-miR-381	CLIP-seq
MIRT2325611	hsa-miR-4262	CLIP-seq
MIRT2325612	hsa-miR-4465	CLIP-seq
MIRT2101223	hsa-miR-4666-3p	CLIP-seq
MIRT2101224	hsa-miR-4698	CLIP-seq
MIRT2101225	hsa-miR-4703-3p	CLIP-seq
MIRT2325613	hsa-miR-520a-3p	CLIP-seq
MIRT2325614	hsa-miR-520b	CLIP-seq
MIRT2325615	hsa-miR-520c-3p	CLIP-seq
MIRT2325616	hsa-miR-520d-3p	CLIP-seq
MIRT2325617	hsa-miR-520e	CLIP-seq
MIRT2325618	hsa-miR-543	CLIP-seq
MIRT2325619	hsa-miR-553	CLIP-seq
MIRT1341991	hsa-miR-122	CLIP-seq
MIRT1341992	hsa-miR-1343	CLIP-seq
MIRT1341995	hsa-miR-223	CLIP-seq
MIRT1341997	hsa-miR-3659	CLIP-seq
MIRT1341999	hsa-miR-3690	CLIP-seq
MIRT1342001	hsa-miR-4254	CLIP-seq
MIRT1342003	hsa-miR-4326	CLIP-seq
MIRT1341991	hsa-miR-122	CLIP-seq
MIRT2325595	hsa-miR-1297	CLIP-seq
MIRT1341992	hsa-miR-1343	CLIP-seq
MIRT2325596	hsa-miR-181a	CLIP-seq
MIRT2325597	hsa-miR-181b	CLIP-seq
MIRT2325598	hsa-miR-181c	CLIP-seq
MIRT2325599	hsa-miR-181d	CLIP-seq
MIRT2325600	hsa-miR-1911	CLIP-seq
MIRT1341993	hsa-miR-197	CLIP-seq
MIRT1341994	hsa-miR-2110	CLIP-seq
MIRT1341995	hsa-miR-223	CLIP-seq
MIRT2325601	hsa-miR-26a	CLIP-seq
MIRT2325602	hsa-miR-26b	CLIP-seq
MIRT2325603	hsa-miR-302a	CLIP-seq
MIRT2325604	hsa-miR-302b	CLIP-seq
MIRT2325605	hsa-miR-302c	CLIP-seq
MIRT2325606	hsa-miR-302d	CLIP-seq
MIRT2325607	hsa-miR-302e	CLIP-seq
MIRT1341996	hsa-miR-3115	CLIP-seq
MIRT1341997	hsa-miR-3659	CLIP-seq
MIRT1341998	hsa-miR-3675-5p	CLIP-seq
MIRT1341999	hsa-miR-3690	CLIP-seq
MIRT2621355	hsa-miR-3692	CLIP-seq
MIRT2325609	hsa-miR-372	CLIP-seq
MIRT2325610	hsa-miR-373	CLIP-seq
MIRT2621356	hsa-miR-376c	CLIP-seq
MIRT1342000	hsa-miR-412	CLIP-seq
MIRT1342001	hsa-miR-4254	CLIP-seq
MIRT2325611	hsa-miR-4262	CLIP-seq
MIRT1342002	hsa-miR-4271	CLIP-seq
MIRT1342003	hsa-miR-4326	CLIP-seq
MIRT2325612	hsa-miR-4465	CLIP-seq
MIRT1342004	hsa-miR-4668-5p	CLIP-seq
MIRT1342005	hsa-miR-4725-3p	CLIP-seq
MIRT2325613	hsa-miR-520a-3p	CLIP-seq
MIRT2325614	hsa-miR-520b	CLIP-seq
MIRT2325615	hsa-miR-520c-3p	CLIP-seq
MIRT2325616	hsa-miR-520d-3p	CLIP-seq
MIRT2325617	hsa-miR-520e	CLIP-seq
MIRT2325618	hsa-miR-543	CLIP-seq
MIRT1341991	hsa-miR-122	CLIP-seq
MIRT2325595	hsa-miR-1297	CLIP-seq
MIRT1341992	hsa-miR-1343	CLIP-seq
MIRT2325596	hsa-miR-181a	CLIP-seq
MIRT2325597	hsa-miR-181b	CLIP-seq
MIRT2325598	hsa-miR-181c	CLIP-seq
MIRT2325599	hsa-miR-181d	CLIP-seq
MIRT2325600	hsa-miR-1911	CLIP-seq
MIRT1341993	hsa-miR-197	CLIP-seq
MIRT1341994	hsa-miR-2110	CLIP-seq
MIRT1341995	hsa-miR-223	CLIP-seq
MIRT2325601	hsa-miR-26a	CLIP-seq
MIRT2325602	hsa-miR-26b	CLIP-seq
MIRT2325603	hsa-miR-302a	CLIP-seq
MIRT2325604	hsa-miR-302b	CLIP-seq
MIRT2325605	hsa-miR-302c	CLIP-seq
MIRT2325606	hsa-miR-302d	CLIP-seq
MIRT2325607	hsa-miR-302e	CLIP-seq
MIRT1341996	hsa-miR-3115	CLIP-seq
MIRT1341997	hsa-miR-3659	CLIP-seq
MIRT1341998	hsa-miR-3675-5p	CLIP-seq
MIRT1341999	hsa-miR-3690	CLIP-seq
MIRT2621355	hsa-miR-3692	CLIP-seq
MIRT2325609	hsa-miR-372	CLIP-seq
MIRT2325610	hsa-miR-373	CLIP-seq
MIRT2621356	hsa-miR-376c	CLIP-seq
MIRT1342000	hsa-miR-412	CLIP-seq
MIRT1342001	hsa-miR-4254	CLIP-seq
MIRT2325611	hsa-miR-4262	CLIP-seq
MIRT1342002	hsa-miR-4271	CLIP-seq
MIRT1342003	hsa-miR-4326	CLIP-seq
MIRT2325612	hsa-miR-4465	CLIP-seq
MIRT1342004	hsa-miR-4668-5p	CLIP-seq
MIRT1342005	hsa-miR-4725-3p	CLIP-seq
MIRT2325613	hsa-miR-520a-3p	CLIP-seq
MIRT2325614	hsa-miR-520b	CLIP-seq
MIRT2325615	hsa-miR-520c-3p	CLIP-seq
MIRT2325616	hsa-miR-520d-3p	CLIP-seq
MIRT2325617	hsa-miR-520e	CLIP-seq
MIRT2325618	hsa-miR-543	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0012505	Component	Endomembrane system	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q8WV19

Protein name

Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1)

Protein function

May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04178	Got1	38 → 155	Got1/Sft2-like family	Family

Sequence

MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGG
IKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHK
KGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS

Sequence length

159

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Neuroblastoma	Neuroblastoma	Pubtator	31959052	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	32907841	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SFT2D1 (SFT2 domain containing 1)