Gene Gene information from NCBI Gene database.
Entrez ID 113178
Gene name Secretory carrier membrane protein 4
Gene symbol SCAMP4
Synonyms (NCBI Gene)
SCAMP-4
Chromosome 19
Chromosome location 19p13.3
Summary Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane region
miRNA miRNA information provided by mirtarbase database.
502
miRTarBase ID miRNA Experiments Reference
MIRT041297 hsa-miR-193b-3p CLASH 23622248
MIRT036439 hsa-miR-1226-3p CLASH 23622248
MIRT699849 hsa-miR-548c-3p HITS-CLIP 23313552
MIRT699848 hsa-miR-6849-3p HITS-CLIP 23313552
MIRT699847 hsa-miR-3190-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183, 32814053
GO:0006887 Process Exocytosis IBA
GO:0015031 Process Protein transport IEA
GO:0016020 Component Membrane IEA
GO:0032588 Component Trans-Golgi network membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613764 30385 ENSG00000227500
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q969E2
Protein name Secretory carrier-associated membrane protein 4 (Secretory carrier membrane protein 4)
Protein function Probably involved in membrane protein trafficking.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04144 SCAMP 5 179 SCAMP family Family
Sequence
Sequence length 229
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DISABILITY WITH STRABISMUS SYNDROME Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinogenesis Carcinogenesis Pubtator 34426610 Associate
★☆☆☆☆
Found in Text Mining only
Leukemia Myeloid Acute Myeloid leukemia Pubtator 34426610 Associate
★☆☆☆☆
Found in Text Mining only
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 36 Mental retardation CLINVAR_DG
★☆☆☆☆
Found in Text Mining only
Pancreatic Neoplasms Pancreatic neoplasm Pubtator 33493138 Stimulate
★☆☆☆☆
Found in Text Mining only
Strabismus Strabismus CLINVAR_DG
★☆☆☆☆
Found in Text Mining only