Gene Gene information from NCBI Gene database.
Entrez ID 11237
Gene name Ring finger protein 24
Gene symbol RNF24
Synonyms (NCBI Gene)
G1L
Chromosome 20
Chromosome location 20p13
Summary This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of thes
miRNA miRNA information provided by mirtarbase database.
529
miRTarBase ID miRNA Experiments Reference
MIRT029537 hsa-miR-26b-5p Microarray 19088304
MIRT687032 hsa-miR-433-5p HITS-CLIP 23313552
MIRT687031 hsa-miR-6502-3p HITS-CLIP 23313552
MIRT687030 hsa-miR-6888-5p HITS-CLIP 23313552
MIRT687029 hsa-miR-4768-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005794 Component Golgi apparatus IDA
GO:0005794 Component Golgi apparatus IEA
GO:0008270 Function Zinc ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612489 13779 ENSG00000101236
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y225
Protein name RING finger protein 24
Protein function May play a role in TRPCs intracellular trafficking.
PDB 2EP4
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13639 zf-RING_2 76 119 Ring finger domain Domain
Sequence
MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY
KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM
PVLQLAQLHSKQDRGPPQGPLPGAENIV
Sequence length 148
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MALE REPRODUCTIVE SYSTEM DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Barrett Esophagus Barrett esophagus BEFREE 25228972
★☆☆☆☆
Found in Text Mining only
Barrett Esophagus Barrett esophagus Pubtator 25228972 Associate
★☆☆☆☆
Found in Text Mining only
Esophageal Neoplasms Esophageal neoplasm Pubtator 25228972 Associate
★☆☆☆☆
Found in Text Mining only
Ovarian Neoplasms Ovarian neoplasm Pubtator 35120576 Associate
★☆☆☆☆
Found in Text Mining only