Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	11201
Gene name	DNA polymerase iota
Gene symbol	POLI
Synonyms (NCBI Gene)	RAD30BRAD3OBeta2
Chromosome	18
Chromosome location	18q21.2
Summary	The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides acr

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Show/Hide all (249)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049053	hsa-miR-92a-3p	CLASH	23622248
MIRT497086	hsa-miR-455-5p	PAR-CLIP	22291592
MIRT450749	hsa-miR-4786-5p	PAR-CLIP	22291592
MIRT450750	hsa-miR-769-5p	PAR-CLIP	22291592
MIRT450748	hsa-miR-548aj-5p	PAR-CLIP	22291592
MIRT450747	hsa-miR-548f-5p	PAR-CLIP	22291592
MIRT450746	hsa-miR-548g-5p	PAR-CLIP	22291592
MIRT450745	hsa-miR-548x-5p	PAR-CLIP	22291592
MIRT450744	hsa-miR-1468-3p	PAR-CLIP	22291592
MIRT290693	hsa-miR-19a-3p	PAR-CLIP	22291592
MIRT290694	hsa-miR-19b-3p	PAR-CLIP	22291592
MIRT497085	hsa-miR-376a-5p	PAR-CLIP	22291592
MIRT450743	hsa-miR-340-5p	PAR-CLIP	22291592
MIRT450742	hsa-miR-3672	PAR-CLIP	22291592
MIRT450741	hsa-miR-6864-3p	PAR-CLIP	22291592
MIRT290698	hsa-miR-548aw	PAR-CLIP	22291592
MIRT290697	hsa-miR-4760-5p	PAR-CLIP	22291592
MIRT290699	hsa-miR-8061	PAR-CLIP	22291592
MIRT450753	hsa-miR-142-3p	PAR-CLIP	22100165
MIRT450752	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT199034	hsa-miR-5197-3p	PAR-CLIP	22100165
MIRT199032	hsa-miR-4255	PAR-CLIP	22100165
MIRT199031	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT450751	hsa-miR-889-3p	PAR-CLIP	22100165
MIRT199033	hsa-miR-3591-5p	PAR-CLIP	22100165
MIRT450749	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT450750	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT450748	hsa-miR-548aj-5p	PAR-CLIP	22100165
MIRT450747	hsa-miR-548f-5p	PAR-CLIP	22100165
MIRT450746	hsa-miR-548g-5p	PAR-CLIP	22100165
MIRT450745	hsa-miR-548x-5p	PAR-CLIP	22100165
MIRT450744	hsa-miR-1468-3p	PAR-CLIP	22100165
MIRT290693	hsa-miR-19a-3p	PAR-CLIP	22100165
MIRT290694	hsa-miR-19b-3p	PAR-CLIP	22100165
MIRT450743	hsa-miR-340-5p	PAR-CLIP	22100165
MIRT450742	hsa-miR-3672	PAR-CLIP	22100165
MIRT450741	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT290698	hsa-miR-548aw	PAR-CLIP	22100165
MIRT450749	hsa-miR-4786-5p	PAR-CLIP	27292025
MIRT497086	hsa-miR-455-5p	PAR-CLIP	22291592
MIRT450749	hsa-miR-4786-5p	PAR-CLIP	22291592
MIRT450750	hsa-miR-769-5p	PAR-CLIP	22291592
MIRT450748	hsa-miR-548aj-5p	PAR-CLIP	22291592
MIRT450747	hsa-miR-548f-5p	PAR-CLIP	22291592
MIRT450746	hsa-miR-548g-5p	PAR-CLIP	22291592
MIRT450745	hsa-miR-548x-5p	PAR-CLIP	22291592
MIRT450744	hsa-miR-1468-3p	PAR-CLIP	22291592
MIRT290693	hsa-miR-19a-3p	PAR-CLIP	22291592
MIRT290694	hsa-miR-19b-3p	PAR-CLIP	22291592
MIRT497085	hsa-miR-376a-5p	PAR-CLIP	22291592
MIRT450743	hsa-miR-340-5p	PAR-CLIP	22291592
MIRT450742	hsa-miR-3672	PAR-CLIP	22291592
MIRT450741	hsa-miR-6864-3p	PAR-CLIP	22291592
MIRT290698	hsa-miR-548aw	PAR-CLIP	22291592
MIRT290697	hsa-miR-4760-5p	PAR-CLIP	22291592
MIRT290699	hsa-miR-8061	PAR-CLIP	22291592
MIRT450753	hsa-miR-142-3p	PAR-CLIP	22100165
MIRT450752	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT199034	hsa-miR-5197-3p	PAR-CLIP	22100165
MIRT199032	hsa-miR-4255	PAR-CLIP	22100165
MIRT199031	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT450751	hsa-miR-889-3p	PAR-CLIP	22100165
MIRT199033	hsa-miR-3591-5p	PAR-CLIP	22100165
MIRT450749	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT450750	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT450748	hsa-miR-548aj-5p	PAR-CLIP	22100165
MIRT450747	hsa-miR-548f-5p	PAR-CLIP	22100165
MIRT450746	hsa-miR-548g-5p	PAR-CLIP	22100165
MIRT450745	hsa-miR-548x-5p	PAR-CLIP	22100165
MIRT450744	hsa-miR-1468-3p	PAR-CLIP	22100165
MIRT290693	hsa-miR-19a-3p	PAR-CLIP	22100165
MIRT290694	hsa-miR-19b-3p	PAR-CLIP	22100165
MIRT450743	hsa-miR-340-5p	PAR-CLIP	22100165
MIRT450742	hsa-miR-3672	PAR-CLIP	22100165
MIRT450741	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT290698	hsa-miR-548aw	PAR-CLIP	22100165
MIRT1247913	hsa-miR-1271	CLIP-seq
MIRT1247914	hsa-miR-1273	CLIP-seq
MIRT1247915	hsa-miR-1273e	CLIP-seq
MIRT1247916	hsa-miR-1276	CLIP-seq
MIRT1247917	hsa-miR-1298	CLIP-seq
MIRT1247918	hsa-miR-139-5p	CLIP-seq
MIRT1247919	hsa-miR-1537	CLIP-seq
MIRT1247920	hsa-miR-181a	CLIP-seq
MIRT1247921	hsa-miR-181b	CLIP-seq
MIRT1247922	hsa-miR-181c	CLIP-seq
MIRT1247923	hsa-miR-181d	CLIP-seq
MIRT1247924	hsa-miR-182	CLIP-seq
MIRT1247925	hsa-miR-1827	CLIP-seq
MIRT1247926	hsa-miR-194	CLIP-seq
MIRT1247927	hsa-miR-224	CLIP-seq
MIRT1247928	hsa-miR-23a	CLIP-seq
MIRT1247929	hsa-miR-23b	CLIP-seq
MIRT1247930	hsa-miR-23c	CLIP-seq
MIRT1247931	hsa-miR-2964a-3p	CLIP-seq
MIRT1247932	hsa-miR-302f	CLIP-seq
MIRT1247933	hsa-miR-3120-5p	CLIP-seq
MIRT1247934	hsa-miR-3143	CLIP-seq
MIRT1247935	hsa-miR-3145-5p	CLIP-seq
MIRT1247936	hsa-miR-3160-3p	CLIP-seq
MIRT1247937	hsa-miR-3174	CLIP-seq
MIRT1247938	hsa-miR-3192	CLIP-seq
MIRT1247939	hsa-miR-3200-3p	CLIP-seq
MIRT1247940	hsa-miR-335	CLIP-seq
MIRT1247941	hsa-miR-3605-5p	CLIP-seq
MIRT1247942	hsa-miR-3620	CLIP-seq
MIRT1247943	hsa-miR-3664-5p	CLIP-seq
MIRT1247944	hsa-miR-3689a-3p	CLIP-seq
MIRT1247945	hsa-miR-3689c	CLIP-seq
MIRT1247946	hsa-miR-3929	CLIP-seq
MIRT1247947	hsa-miR-4252	CLIP-seq
MIRT1247948	hsa-miR-4262	CLIP-seq
MIRT1247949	hsa-miR-4292	CLIP-seq
MIRT1247950	hsa-miR-4311	CLIP-seq
MIRT1247951	hsa-miR-4419b	CLIP-seq
MIRT1247952	hsa-miR-4459	CLIP-seq
MIRT1247953	hsa-miR-4478	CLIP-seq
MIRT1247954	hsa-miR-4486	CLIP-seq
MIRT1247955	hsa-miR-4487	CLIP-seq
MIRT1247956	hsa-miR-4522	CLIP-seq
MIRT1247957	hsa-miR-4649-3p	CLIP-seq
MIRT1247958	hsa-miR-4649-5p	CLIP-seq
MIRT1247959	hsa-miR-4662a-5p	CLIP-seq
MIRT1247960	hsa-miR-4668-5p	CLIP-seq
MIRT1247961	hsa-miR-4695-5p	CLIP-seq
MIRT1247962	hsa-miR-4722-5p	CLIP-seq
MIRT1247963	hsa-miR-4728-5p	CLIP-seq
MIRT1247964	hsa-miR-4747-3p	CLIP-seq
MIRT1247965	hsa-miR-4768-3p	CLIP-seq
MIRT1247966	hsa-miR-4797-5p	CLIP-seq
MIRT1247967	hsa-miR-485-5p	CLIP-seq
MIRT1247968	hsa-miR-490-3p	CLIP-seq
MIRT1247969	hsa-miR-508-5p	CLIP-seq
MIRT1247970	hsa-miR-515-5p	CLIP-seq
MIRT1247971	hsa-miR-543	CLIP-seq
MIRT1247972	hsa-miR-558	CLIP-seq
MIRT1247973	hsa-miR-583	CLIP-seq
MIRT1247974	hsa-miR-658	CLIP-seq
MIRT1247975	hsa-miR-664	CLIP-seq
MIRT1247976	hsa-miR-888	CLIP-seq
MIRT1247977	hsa-miR-889	CLIP-seq
MIRT1247978	hsa-miR-921	CLIP-seq
MIRT1247979	hsa-miR-940	CLIP-seq
MIRT1247980	hsa-miR-96	CLIP-seq
MIRT1247915	hsa-miR-1273e	CLIP-seq
MIRT1247925	hsa-miR-1827	CLIP-seq
MIRT2073174	hsa-miR-190	CLIP-seq
MIRT2073175	hsa-miR-190b	CLIP-seq
MIRT1247931	hsa-miR-2964a-3p	CLIP-seq
MIRT1247932	hsa-miR-302f	CLIP-seq
MIRT1247936	hsa-miR-3160-3p	CLIP-seq
MIRT2073176	hsa-miR-3160-5p	CLIP-seq
MIRT1247937	hsa-miR-3174	CLIP-seq
MIRT1247938	hsa-miR-3192	CLIP-seq
MIRT2073177	hsa-miR-3664-3p	CLIP-seq
MIRT1247944	hsa-miR-3689a-3p	CLIP-seq
MIRT1247945	hsa-miR-3689c	CLIP-seq
MIRT1247946	hsa-miR-3929	CLIP-seq
MIRT1247951	hsa-miR-4419b	CLIP-seq
MIRT2073178	hsa-miR-4433	CLIP-seq
MIRT1247952	hsa-miR-4459	CLIP-seq
MIRT1247953	hsa-miR-4478	CLIP-seq
MIRT1247955	hsa-miR-4487	CLIP-seq
MIRT2073179	hsa-miR-4520a-3p	CLIP-seq
MIRT2073180	hsa-miR-4520b-3p	CLIP-seq
MIRT1247957	hsa-miR-4649-3p	CLIP-seq
MIRT1247961	hsa-miR-4695-5p	CLIP-seq
MIRT1247962	hsa-miR-4722-5p	CLIP-seq
MIRT1247963	hsa-miR-4728-5p	CLIP-seq
MIRT2073181	hsa-miR-4753-3p	CLIP-seq
MIRT1247965	hsa-miR-4768-3p	CLIP-seq
MIRT2073182	hsa-miR-4768-5p	CLIP-seq
MIRT1247967	hsa-miR-485-5p	CLIP-seq
MIRT1247968	hsa-miR-490-3p	CLIP-seq
MIRT2073183	hsa-miR-510	CLIP-seq
MIRT2073184	hsa-miR-512-5p	CLIP-seq
MIRT2073185	hsa-miR-526b	CLIP-seq
MIRT1247972	hsa-miR-558	CLIP-seq
MIRT2073186	hsa-miR-578	CLIP-seq
MIRT1247973	hsa-miR-583	CLIP-seq
MIRT1247974	hsa-miR-658	CLIP-seq
MIRT2073187	hsa-miR-890	CLIP-seq
MIRT1247978	hsa-miR-921	CLIP-seq
MIRT2073188	hsa-miR-935	CLIP-seq
MIRT1247979	hsa-miR-940	CLIP-seq
MIRT2300290	hsa-miR-1295	CLIP-seq
MIRT2300291	hsa-miR-1299	CLIP-seq
MIRT2300292	hsa-miR-1303	CLIP-seq
MIRT2300293	hsa-miR-15a	CLIP-seq
MIRT2300294	hsa-miR-15b	CLIP-seq
MIRT2300295	hsa-miR-16	CLIP-seq
MIRT1247925	hsa-miR-1827	CLIP-seq
MIRT2300296	hsa-miR-195	CLIP-seq
MIRT2300297	hsa-miR-3126-3p	CLIP-seq
MIRT2300298	hsa-miR-3140-3p	CLIP-seq
MIRT1247936	hsa-miR-3160-3p	CLIP-seq
MIRT1247937	hsa-miR-3174	CLIP-seq
MIRT1247938	hsa-miR-3192	CLIP-seq
MIRT1247944	hsa-miR-3689a-3p	CLIP-seq
MIRT1247945	hsa-miR-3689c	CLIP-seq
MIRT1247946	hsa-miR-3929	CLIP-seq
MIRT2300299	hsa-miR-424	CLIP-seq
MIRT2300300	hsa-miR-4253	CLIP-seq
MIRT2300301	hsa-miR-4279	CLIP-seq
MIRT1247951	hsa-miR-4419b	CLIP-seq
MIRT2300302	hsa-miR-4422	CLIP-seq
MIRT2073178	hsa-miR-4433	CLIP-seq
MIRT1247953	hsa-miR-4478	CLIP-seq
MIRT1247955	hsa-miR-4487	CLIP-seq
MIRT2300303	hsa-miR-451b	CLIP-seq
MIRT1247957	hsa-miR-4649-3p	CLIP-seq
MIRT2300304	hsa-miR-4661-5p	CLIP-seq
MIRT1247963	hsa-miR-4728-5p	CLIP-seq
MIRT1247964	hsa-miR-4747-3p	CLIP-seq
MIRT2300305	hsa-miR-4761-5p	CLIP-seq
MIRT1247965	hsa-miR-4768-3p	CLIP-seq
MIRT1247968	hsa-miR-490-3p	CLIP-seq
MIRT2300306	hsa-miR-497	CLIP-seq
MIRT2300307	hsa-miR-520f	CLIP-seq
MIRT1247972	hsa-miR-558	CLIP-seq
MIRT1247974	hsa-miR-658	CLIP-seq
MIRT2300308	hsa-miR-765	CLIP-seq
MIRT2300309	hsa-miR-875-3p	CLIP-seq
MIRT1247978	hsa-miR-921	CLIP-seq
MIRT2300310	hsa-miR-922	CLIP-seq
MIRT2456866	hsa-miR-3136-3p	CLIP-seq
MIRT2456867	hsa-miR-4637	CLIP-seq
MIRT2456868	hsa-miR-548aa	CLIP-seq
MIRT1247933	hsa-miR-3120-5p	CLIP-seq
MIRT1247943	hsa-miR-3664-5p	CLIP-seq
MIRT1247956	hsa-miR-4522	CLIP-seq
MIRT1247966	hsa-miR-4797-5p	CLIP-seq
MIRT1247970	hsa-miR-515-5p	CLIP-seq
MIRT2597058	hsa-miR-759	CLIP-seq
MIRT1247933	hsa-miR-3120-5p	CLIP-seq
MIRT2073177	hsa-miR-3664-3p	CLIP-seq
MIRT1247943	hsa-miR-3664-5p	CLIP-seq
MIRT2300300	hsa-miR-4253	CLIP-seq
MIRT2073178	hsa-miR-4433	CLIP-seq
MIRT1247952	hsa-miR-4459	CLIP-seq
MIRT1247956	hsa-miR-4522	CLIP-seq
MIRT1247961	hsa-miR-4695-5p	CLIP-seq
MIRT2688344	hsa-miR-4761-3p	CLIP-seq
MIRT1247965	hsa-miR-4768-3p	CLIP-seq
MIRT1247966	hsa-miR-4797-5p	CLIP-seq
MIRT2073183	hsa-miR-510	CLIP-seq
MIRT2073184	hsa-miR-512-5p	CLIP-seq
MIRT1247970	hsa-miR-515-5p	CLIP-seq
MIRT2597058	hsa-miR-759	CLIP-seq

Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003684	Function	Damaged DNA binding	IEA
GO:0003887	Function	DNA-directed DNA polymerase activity	IBA
GO:0003887	Function	DNA-directed DNA polymerase activity	IEA
GO:0003887	Function	DNA-directed DNA polymerase activity	TAS	10458907
GO:0005515	Function	Protein binding	IPI	16189514, 16763556, 18923427, 19060904, 21516116, 25416956, 30659753, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS	10458907
GO:0006260	Process	DNA replication	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006281	Process	DNA repair	TAS	10458907
GO:0006974	Process	DNA damage response	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0016779	Function	Nucleotidyltransferase activity	IEA
GO:0019985	Process	Translesion synthesis	IBA
GO:0019985	Process	Translesion synthesis	IEA
GO:0034061	Function	DNA polymerase activity	IEA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0042276	Process	Error-prone translesion synthesis	TAS
GO:0046872	Function	Metal ion binding	IEA
GO:0071897	Process	DNA biosynthetic process	IEA

MIM	HGNC	e!Ensembl
605252	9182	ENSG00000101751

Q9UNA4

Protein name

DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)

Protein function

Error-prone DNA polymerase specifically involved in DNA repair (PubMed:11013228, PubMed:11387224). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls (PubMed:1

PDB

1T3N , 1ZET , 2ALZ , 2DPI , 2DPJ , 2FLL , 2FLN , 2FLP , 2KHU , 2KHW , 2KTF , 2L0F , 2L0G , 2MBB , 3EPG , 3EPI , 3G6V , 3G6X , 3G6Y , 3GV5 , 3GV7 , 3GV8 , 3H40 , 3H4B , 3H4D , 3NGD , 3OSN , 3Q8P , 3Q8Q , 3Q8R , 3Q8S , 4EBC , 4EBD , 4EBE , 4EYH , 4EYI , 4FS1 , 4FS2 , 5KT2 , 5KT3 , 5KT4 , 5KT5 , 5KT6 , 5KT7 , 5ULW , 5ULX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00817	IMS	58 → 236	impB/mucB/samB family	Family
PF11799	IMS_C	320 → 446	impB/mucB/samB family C-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Highly expressed in testis. {ECO:0000269|PubMed:10458907, ECO:0000269|PubMed:11387224}.

Sequence

MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQ
EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
QKELLAEWKRAGSDFHIGHK

Sequence length

740

Interactions

View interactions

	KEGG		Reactome
	Fanconi anemia pathway		Translesion synthesis by POLI Termination of translesion DNA synthesis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ASTHMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHILDHOOD ONSET ASTHMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ERYTHEMATOSQUAMOUS DERMATOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY SKIN DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS VULGARIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEBORRHEIC DERMATITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (36)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	15609317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	GWASCAT_DG	30929738		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bladder Neoplasm	Bladder Neoplasm	BEFREE	23922701		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	15313897, 30829610		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	27485818, 30829610	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	LHGDN	12410315		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	36526675	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	23922701		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	15609317, 30060029		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	18194848		★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood asthma	Asthma	GWASCAT_DG	30929738		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	30617956		★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	34887565	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	GWASCAT_DG	30595370		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	22509890		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	22509890, 26097541	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	22509890, 28905458	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi anemia	Pubtator	33376220	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	17499043	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	30617956		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leiomyosarcoma	Leiomyosarcoma	Pubtator	35201535	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	15313897, 30829610		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	15609317, 30060029		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	19861517		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	23922701		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	15313897		★★★★★ ★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	GWASDB_DG	19629137		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22509890		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	28777933	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	35955705	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	19861517		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psoriasis	Psoriasis	GWASCAT_DG	23143594, 25574825, 25903422		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psoriasis	Psoriasis	GWASDB_DG	23143594		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell carcinoma	Carcinoma	BEFREE	15609317, 18194848		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	22509890, 27057634, 28905458		★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	23922701	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

POLI (DNA polymerase iota)