Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	11141
Gene name	Interleukin 1 receptor accessory protein like 1
Gene symbol	IL1RAPL1
Synonyms (NCBI Gene)	IL-1-RAPL-1IL-1RAPL-1IL1R8IL1RAPLIL1RAPL-1MRX10MRX21MRX34OPHN4TIGIRR-2
Chromosome	X
Chromosome location	Xp21.3-p21.2
Summary	The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane do

Show/Hide all (6)

SNP ID	Visualize variation	Clinical significance	Consequence
rs122461160	C>A	Pathogenic	Coding sequence variant, stop gained
rs122461161	G>A	Pathogenic	Coding sequence variant, stop gained
rs878853146	TTGGGAAAGT>-	Pathogenic	Frameshift variant, coding sequence variant
rs886041775	G>A	Pathogenic	Splice donor variant
rs1064795372	AGA>-	Likely-pathogenic, not-provided	Coding sequence variant, inframe deletion
rs1569203705	C>T	Pathogenic	Coding sequence variant, stop gained

378

Show/Hide all (378)

miRTarBase ID	miRNA	Experiments	Reference
MIRT053613	hsa-miR-151a-5p	Luciferase reporter assayqRT-PCRWestern blot	22928040
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628102	hsa-miR-663b	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT1064396	hsa-miR-1269	CLIP-seq
MIRT1064397	hsa-miR-1269b	CLIP-seq
MIRT1064398	hsa-miR-1288	CLIP-seq
MIRT1064399	hsa-miR-3158-5p	CLIP-seq
MIRT1064400	hsa-miR-3654	CLIP-seq
MIRT1064401	hsa-miR-378	CLIP-seq
MIRT1064402	hsa-miR-378b	CLIP-seq
MIRT1064403	hsa-miR-378c	CLIP-seq
MIRT1064404	hsa-miR-378d	CLIP-seq
MIRT1064405	hsa-miR-378e	CLIP-seq
MIRT1064406	hsa-miR-378f	CLIP-seq
MIRT1064407	hsa-miR-378h	CLIP-seq
MIRT1064408	hsa-miR-378i	CLIP-seq
MIRT1064409	hsa-miR-422a	CLIP-seq
MIRT1064410	hsa-miR-4269	CLIP-seq
MIRT1064411	hsa-miR-4418	CLIP-seq
MIRT1064412	hsa-miR-4515	CLIP-seq
MIRT1064413	hsa-miR-4645-5p	CLIP-seq
MIRT1064414	hsa-miR-4673	CLIP-seq
MIRT1064415	hsa-miR-4740-5p	CLIP-seq
MIRT1064416	hsa-miR-509-3-5p	CLIP-seq
MIRT1064417	hsa-miR-509-5p	CLIP-seq
MIRT2015297	hsa-miR-1915	CLIP-seq
MIRT2015298	hsa-miR-2964a-5p	CLIP-seq
MIRT2015299	hsa-miR-4714-3p	CLIP-seq
MIRT2015300	hsa-miR-4726-3p	CLIP-seq

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005102	Function	Signaling receptor binding	ISS
GO:0005515	Function	Protein binding	IPI	12783849, 21940441
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	12783849
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	IBA
GO:0009986	Component	Cell surface	IBA
GO:0009986	Component	Cell surface	ISS
GO:0010975	Process	Regulation of neuron projection development	ISS
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019966	Function	Interleukin-1 binding	IDA	12783849
GO:0030182	Process	Neuron differentiation	ISS
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0042995	Component	Cell projection	IEA
GO:0045211	Component	Postsynaptic membrane	NAS	21940441
GO:0045920	Process	Negative regulation of exocytosis	IBA
GO:0045920	Process	Negative regulation of exocytosis	IDA	12783849
GO:0051965	Process	Positive regulation of synapse assembly	ISS
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	ISS
GO:0061809	Function	NAD+ nucleosidase activity, cyclic ADP-ribose generating	IEA
GO:0097105	Process	Presynaptic membrane assembly	ISS
GO:0098978	Component	Glutamatergic synapse	IDA	21926414
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098978	Component	Glutamatergic synapse	IMP	21926414
GO:0099175	Process	Regulation of postsynapse organization	IDA	21926414
GO:0099175	Process	Regulation of postsynapse organization	IMP	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IDA	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IMP	21926414
GO:0099560	Process	Synaptic membrane adhesion	ISS
GO:1905606	Process	Regulation of presynapse assembly	IDA	21926414
GO:1905606	Process	Regulation of presynapse assembly	IEA
GO:1905606	Process	Regulation of presynapse assembly	IMP	21926414

MIM	HGNC	e!Ensembl
300206	5996	ENSG00000169306

Q9NZN1

Protein name

Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1)

Protein function

May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:12783849). May activate the MAP kinase JNK (PubMed:15123616). Plays a role in neurite outgrowth (By similar

PDB

1T3G , 4M92 , 5WY8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF18452	Ig_6	92 → 143	Immunoglobulin domain	Domain
PF00047	ig	251 → 348	Immunoglobulin domain	Domain
PF01582	TIR	404 → 579	TIR domain	Family

Tissue specificity

TISSUE SPECIFICITY: Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta,

Sequence

MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI
RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI
RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL
WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK
PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE
SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL
AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN
QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN
YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH
GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL
ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ
RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW

Sequence length

696

Interactions

View interactions

	Reactome
			Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
IL1RAPL1-related disorder	Likely pathogenic	rs1064795372	RCV000509346	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual disability	Pathogenic; Likely pathogenic	rs878853146, rs1933958646	RCV000224084 RCV001260739	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual disability, X-linked 21	Likely pathogenic; Pathogenic	rs2147259265, rs2147251555, rs2147258610, rs781674023, rs122461160, rs122461161, rs2519091663, rs2518875196, rs2518941201, rs1569208908, rs1569203705	RCV001527626 RCV001775394 RCV001779415 RCV001814756 RCV000012235 View all (6 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (21)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTISM SPECTRUM DISORDER	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL DISABILITIES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
History of neurodevelopmental disorder	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 21	—	CTD, Disgenet, HPO CTD, Disgenet, HPO CTD, Disgenet, HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL RETARDATION	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL RETARDATION, X-LINKED NONSYNDROMIC	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROTIC DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Non-syndromic X-linked intellectual disability	Uncertain significance; Benign	ClinVar ClinGen, GWAS catalog	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Nonpapillary renal cell carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Uncertain significance	ClinVar Disgenet, GWAS catalog Disgenet, GWAS catalog	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
SCHIZOPHRENIA AND RELATED DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VITILIGO	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED INTELLECTUAL DISABILITY	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED NON-SYNDROMIC INTELLECTUAL DISABILITY	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (73)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
2-3 toe syndactyly	Syndactyly Of The Toes	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenal Hyperplasia Congenital	Congenital adrenal hyperplasia	Pubtator	12940459	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	28120837		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	28120837	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atkin syndrome	Atkin-Flaitz syndrome	CLINGEN_DG	10471494, 16470793, 18801879, 19012350, 24680889, 28576939		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atkin syndrome	Atkin-Flaitz syndrome	GENOMICS_ENGLAND_DG	19012350		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atkin syndrome	Atkin-Flaitz syndrome	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	20479760, 25305082	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorders	Autism Spectrum Disorder	CTD_human_DG	20479760		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	20479890, 21491612, 23613341, 23785489, 25305082, 30548231		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic behavior	Autism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	18801879, 20437600, 20479890, 21384559, 21926414, 23785489		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	CTD_human_DG	18801879, 20437600		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	HPO_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autoimmune Diseases	Autoimmune Diseases	BEFREE	31018956, 31387327		★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	31018956		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	18253029		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	LHGDN	18253029		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bronchopulmonary Dysplasia	Bronchopulmonary Dysplasia	GWASDB_DG	21836138		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	20838585		★★★★★ ★☆☆☆☆ Found in Text Mining only
Class III malocclusion	Malocclusion	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Coffin-Lowry syndrome	Coffin-Lowry Syndrome	BEFREE	8826457		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	28576939		★★★★★ ★☆☆☆☆ Found in Text Mining only
Complex Glycerol Kinase Deficiency	Complex Glycerol Kinase Deficiency	BEFREE	15300857		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Abnormalities	Congenital abnormalities	Pubtator	21933724, 25305082	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	21271657		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital hypoplasia of adrenal gland	Congenital adrenal hypoplasia	BEFREE	12940459		★★★★★ ★☆☆☆☆ Found in Text Mining only
Contiguous gene syndrome	Contiguous gene syndrome	BEFREE	12940459, 21271657		★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive Disorder Major	Major depressive disorder	Pubtator	27440233	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	27761175	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	31018956		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysmorphic features	Dysmorphic Features	BEFREE	21933724		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysmorphism	Dysmorphism	BEFREE	21484992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Facial paralysis	Facial paralysis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Iga nephropathy	Pubtator	22318827	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	21926414		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	10757639, 12940459, 14610352, 15300857, 16118346, 16470793, 18801879, 21484992, 21933724, 22456342, 23613341, 23785489, 25305082, 26290131, 27470653, 28576939, 30103804, 30548231 View all (3 more)		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Intellectual developmental disorder	Pubtator	10882729, 12940459, 21933724, 22456342, 25305082, 30103804, 33774333, 34452636	Associate	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Liver carcinoma	Liver carcinoma	BEFREE	27988500		★★★★★ ★☆☆☆☆ Found in Text Mining only
Macrocephaly	Macrocephaly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28882220		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	28533483		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meckel Diverticulum	Meckel Diverticulum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	CTD_human_DG	22535842		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	BEFREE	27988500		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mental Retardation	Mental retardation	BEFREE	10757639, 12940459, 14610352, 15300857, 16118346, 18801879, 22456342, 23785489		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mental Retardation	Mental retardation	CLINVAR_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mental Retardation, X-Linked	Mental retardation	BEFREE	15300857, 1605217, 16221525, 16470793, 19012350, 21384559, 21926414, 23785489		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	CTD_human_DG	18801879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	LHGDN	19012350		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	GENOMICS_ENGLAND_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked 1	Mental Retardation, X-Linked	ORPHANET_DG	16470793, 19012350		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked 1	Mental Retardation, X-Linked	BEFREE	19012350		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked 19	Mental Retardation, X-Linked	BEFREE	8826457		★★★★★ ★☆☆☆☆ Found in Text Mining only
MENTAL RETARDATION, X-LINKED 34 (disorder)	Mental retardation	CLINGEN_DG	10471494, 16470793, 18801879, 19012350, 24680889, 28576939		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild Mental Retardation	Mental retardation	BEFREE	12428212, 23613341		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild neurosensory hearing impairment	Neurosensory Hearing impairment	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Moderate intellectual disability	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood disorder	Pubtator	27440233	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Pervasive Development Disorder	Autism spectrum disorder	BEFREE	23613341, 23785489, 25305082		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	31376255		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	20479760	Associate	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Schizophrenia and related disorders	Schizophrenia	BEFREE	21982423		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia and related disorders	Schizophrenia	PSYGENET_DG	21982423		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Severe intellectual disability	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Synophrys	Synophrys	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Tonic - clonic seizures	Seizure	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Vitiligo	Vitiligo	GWASCAT_DG	27723757		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-linked Adrenal Hypoplasia	Adrenal Hypoplasia, X-Linked	BEFREE	12940459		★★★★★ ★☆☆☆☆ Found in Text Mining only
X-linked non-syndromic intellectual disability	Non-Syndromic Intellectual Disability, X-Linked	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

IL1RAPL1 (interleukin 1 receptor accessory protein like 1)