MYOCOS (myocilin opposite strand)

Gene

• Entrez ID: 110806290
• Gene name: Myocilin opposite strand
• Gene symbol: MYOCOS
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1q24.3

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A0A1B0GUC4
• Protein name: Myocilin opposite strand protein
• Sequence:

  MAQKSLANNSINLPYKDLTSEVTRRRVTMITRKEIITQKSDEAKEMLSHLDLEQAPPPHR
  TYLTVPPAPPPSPAEDPTPDGLSFKIREAGTSVSSDFSSWKAKVSKFH

• Sequence length: 108

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPEN-ANGLE GLAUCOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Combined immunodeficiency	Severe combined immunodeficiency disease	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Glaucoma	Glaucoma	GWASCAT_DG	30104761		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Glaucoma	Glaucoma	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA 1, OPEN ANGLE, A	Glaucoma	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Glaucoma, Primary Open Angle	Glaucoma	CLINVAR_DG	10815160, 11535458, 11803488, 11815346, 12189160, 12872267, 17562996, 17615537, 19023451, 20021252, 22933836, 23304066, 24732711, 9005853, 9639450		★☆☆☆☆ Found in Text Mining only
Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Lymphopenia	Lymphopenia	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Severe Combined Immunodeficiency	Severe combined immunodeficiency disease	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only