Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	11078
Gene name	TRIO and F-actin binding protein
Gene symbol	TRIOBP
Synonyms (NCBI Gene)	DFNB28HRIHFB2122TAP68TARAdJ37E16.4
Chromosome	22
Chromosome location	22q13.1
Summary	This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility

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SNP ID	Visualize variation	Clinical significance	Consequence
rs34066624	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign, not-provided, benign-likely-benign	Genic upstream transcript variant, coding sequence variant, missense variant
rs55821172	G>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant
rs118204026	C>G,T	Pathogenic	Missense variant, coding sequence variant, stop gained, genic upstream transcript variant
rs118204027	C>T	Pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs118204028	C>T	Pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs118204029	C>T	Pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs118204030	C>T	Pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs118204031	C>T	Pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs138139146	G>A	Conflicting-interpretations-of-pathogenicity, benign-likely-benign	Coding sequence variant, genic downstream transcript variant, missense variant
rs143157673	C>T	Conflicting-interpretations-of-pathogenicity, benign-likely-benign	Missense variant, coding sequence variant, genic upstream transcript variant
rs199594270	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs200045032	G>T	Uncertain-significance, pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant
rs200793989	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, synonymous variant
rs201117318	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic upstream transcript variant
rs368119524	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs375936342	C>T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, synonymous variant, coding sequence variant
rs377748152	C>G,T	Likely-pathogenic	Stop gained, missense variant, coding sequence variant, genic upstream transcript variant
rs549095193	G>A,T	Pathogenic	Missense variant, coding sequence variant, genic upstream transcript variant
rs727503528	C>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs747619979	G>A	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs750078356	C>G,T	Pathogenic	Genic upstream transcript variant, coding sequence variant, missense variant, stop gained
rs750744696	GA>-	Likely-pathogenic	Genic upstream transcript variant, frameshift variant, coding sequence variant
rs776720591	A>G	Likely-pathogenic	Splice acceptor variant
rs1057520081	T>C,G	Likely-pathogenic	Splice donor variant, genic upstream transcript variant
rs1060499809	C>T	Pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs1228392408	C>T	Pathogenic	Stop gained, coding sequence variant, genic upstream transcript variant
rs1233777224	GA>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic upstream transcript variant
rs1555894574	AGAGGTGGGTAGAGTCCCAGGGCCCA>-	Pathogenic	Genic upstream transcript variant, intron variant, coding sequence variant, splice donor variant
rs1555896285	AG>-	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs1569034190	C>G	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs1569040134	C>T	Likely-pathogenic	Genic upstream transcript variant, missense variant, coding sequence variant
rs1569042640	CCTGTGTGCATTGGGCACCGGGATGCACCCTCCTTCTCATCCCCACC>-	Pathogenic	Genic upstream transcript variant, coding sequence variant, frameshift variant
rs1569042693	C>A	Pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs1569042782	CTGATCCCCCAAG>-	Pathogenic	Genic upstream transcript variant, coding sequence variant, frameshift variant
rs1569046250	G>T	Pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs1601632909	CG>-	Pathogenic	Genic upstream transcript variant, coding sequence variant, frameshift variant
rs1601639680	GA>-	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, frameshift variant

443

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miRTarBase ID	miRNA	Experiments	Reference
MIRT029872	hsa-miR-26b-5p	Microarray	19088304
MIRT716799	hsa-miR-4312	HITS-CLIP	19536157
MIRT716798	hsa-miR-3912-5p	HITS-CLIP	19536157
MIRT716797	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT698071	hsa-miR-302f	HITS-CLIP	23313552
MIRT698070	hsa-miR-6753-5p	HITS-CLIP	23313552
MIRT698069	hsa-miR-5582-5p	HITS-CLIP	23313552
MIRT698068	hsa-miR-296-3p	HITS-CLIP	23313552
MIRT698067	hsa-miR-4733-3p	HITS-CLIP	23313552
MIRT698066	hsa-miR-4691-3p	HITS-CLIP	23313552
MIRT698065	hsa-miR-6823-5p	HITS-CLIP	23313552
MIRT698064	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT698063	hsa-miR-3612	HITS-CLIP	23313552
MIRT698062	hsa-miR-650	HITS-CLIP	23313552
MIRT698061	hsa-miR-4443	HITS-CLIP	23313552
MIRT698060	hsa-miR-6515-5p	HITS-CLIP	23313552
MIRT698059	hsa-miR-3194-5p	HITS-CLIP	23313552
MIRT686510	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686509	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686508	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686507	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686506	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686505	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686504	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686503	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686502	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686501	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686500	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686499	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686498	hsa-miR-302e	HITS-CLIP	23313552
MIRT686497	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686496	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686495	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686494	hsa-miR-520b	HITS-CLIP	23313552
MIRT686493	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686492	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686491	hsa-miR-520e	HITS-CLIP	23313552
MIRT686488	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686487	hsa-miR-532-5p	HITS-CLIP	23313552
MIRT686486	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686484	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686483	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT686482	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686481	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686480	hsa-miR-1254	HITS-CLIP	23313552
MIRT686479	hsa-miR-3116	HITS-CLIP	23313552
MIRT686478	hsa-miR-661	HITS-CLIP	23313552
MIRT686477	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686476	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT686475	hsa-miR-4633-5p	HITS-CLIP	23313552
MIRT686474	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686473	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686510	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686509	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686508	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686507	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686506	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686505	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686504	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686503	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686502	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686501	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686500	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686499	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686498	hsa-miR-302e	HITS-CLIP	23313552
MIRT686497	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686496	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686495	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686494	hsa-miR-520b	HITS-CLIP	23313552
MIRT686493	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686492	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686491	hsa-miR-520e	HITS-CLIP	23313552
MIRT686490	hsa-miR-3200-3p	HITS-CLIP	23313552
MIRT686489	hsa-miR-6813-3p	HITS-CLIP	23313552
MIRT686488	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686487	hsa-miR-532-5p	HITS-CLIP	23313552
MIRT686486	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686485	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT686484	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686483	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT686482	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686481	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686480	hsa-miR-1254	HITS-CLIP	23313552
MIRT686479	hsa-miR-3116	HITS-CLIP	23313552
MIRT686478	hsa-miR-661	HITS-CLIP	23313552
MIRT686477	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686476	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT686475	hsa-miR-4633-5p	HITS-CLIP	23313552
MIRT686474	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686473	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT607635	hsa-miR-541-3p	HITS-CLIP	24906430
MIRT607634	hsa-miR-654-5p	HITS-CLIP	24906430
MIRT607633	hsa-miR-92a-2-5p	HITS-CLIP	24906430
MIRT607632	hsa-miR-6769a-5p	HITS-CLIP	24906430
MIRT607631	hsa-miR-6769b-5p	HITS-CLIP	24906430
MIRT607630	hsa-miR-6748-5p	HITS-CLIP	24906430
MIRT607629	hsa-miR-3911	HITS-CLIP	24906430
MIRT607628	hsa-miR-644a	HITS-CLIP	24906430
MIRT395630	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT607627	hsa-miR-6741-5p	HITS-CLIP	24906430
MIRT395624	hsa-miR-147a	HITS-CLIP	24906430
MIRT607626	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT443007	hsa-miR-497-3p	PAR-CLIP	22100165
MIRT443006	hsa-miR-6715a-3p	PAR-CLIP	22100165
MIRT443005	hsa-miR-7156-3p	PAR-CLIP	22100165
MIRT443004	hsa-miR-1301-3p	PAR-CLIP	22100165
MIRT443003	hsa-miR-5047	PAR-CLIP	22100165
MIRT716799	hsa-miR-4312	HITS-CLIP	19536157
MIRT716798	hsa-miR-3912-5p	HITS-CLIP	19536157
MIRT716797	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT698071	hsa-miR-302f	HITS-CLIP	23313552
MIRT698070	hsa-miR-6753-5p	HITS-CLIP	23313552
MIRT698069	hsa-miR-5582-5p	HITS-CLIP	23313552
MIRT698068	hsa-miR-296-3p	HITS-CLIP	23313552
MIRT698067	hsa-miR-4733-3p	HITS-CLIP	23313552
MIRT698066	hsa-miR-4691-3p	HITS-CLIP	23313552
MIRT698065	hsa-miR-6823-5p	HITS-CLIP	23313552
MIRT698064	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT698063	hsa-miR-3612	HITS-CLIP	23313552
MIRT698062	hsa-miR-650	HITS-CLIP	23313552
MIRT698061	hsa-miR-4443	HITS-CLIP	23313552
MIRT698060	hsa-miR-6515-5p	HITS-CLIP	23313552
MIRT698059	hsa-miR-3194-5p	HITS-CLIP	23313552
MIRT686510	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686509	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686508	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686507	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686506	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686505	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686504	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686503	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686502	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686501	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686500	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686499	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686498	hsa-miR-302e	HITS-CLIP	23313552
MIRT686497	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686496	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686495	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686494	hsa-miR-520b	HITS-CLIP	23313552
MIRT686493	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686492	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686491	hsa-miR-520e	HITS-CLIP	23313552
MIRT686488	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686487	hsa-miR-532-5p	HITS-CLIP	23313552
MIRT686486	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686484	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686483	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT686482	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686481	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686480	hsa-miR-1254	HITS-CLIP	23313552
MIRT686479	hsa-miR-3116	HITS-CLIP	23313552
MIRT686478	hsa-miR-661	HITS-CLIP	23313552
MIRT686477	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686476	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT686475	hsa-miR-4633-5p	HITS-CLIP	23313552
MIRT686474	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686473	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686510	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686509	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686508	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686507	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686506	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686505	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686504	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686503	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686502	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686501	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686500	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686499	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686498	hsa-miR-302e	HITS-CLIP	23313552
MIRT686497	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686496	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686495	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686494	hsa-miR-520b	HITS-CLIP	23313552
MIRT686493	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686492	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686491	hsa-miR-520e	HITS-CLIP	23313552
MIRT686490	hsa-miR-3200-3p	HITS-CLIP	23313552
MIRT686489	hsa-miR-6813-3p	HITS-CLIP	23313552
MIRT686488	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686487	hsa-miR-532-5p	HITS-CLIP	23313552
MIRT686486	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686485	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT686484	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686483	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT686482	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686481	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686480	hsa-miR-1254	HITS-CLIP	23313552
MIRT686479	hsa-miR-3116	HITS-CLIP	23313552
MIRT686478	hsa-miR-661	HITS-CLIP	23313552
MIRT686477	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686476	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT686475	hsa-miR-4633-5p	HITS-CLIP	23313552
MIRT686474	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686473	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT443007	hsa-miR-497-3p	PAR-CLIP	22100165
MIRT443006	hsa-miR-6715a-3p	PAR-CLIP	22100165
MIRT443005	hsa-miR-7156-3p	PAR-CLIP	22100165
MIRT443004	hsa-miR-1301-3p	PAR-CLIP	22100165
MIRT443003	hsa-miR-5047	PAR-CLIP	22100165
MIRT1456269	hsa-let-7a	CLIP-seq
MIRT1456270	hsa-let-7b	CLIP-seq
MIRT1456271	hsa-let-7c	CLIP-seq
MIRT1456272	hsa-let-7d	CLIP-seq
MIRT1456273	hsa-let-7e	CLIP-seq
MIRT1456274	hsa-let-7f	CLIP-seq
MIRT1456275	hsa-let-7g	CLIP-seq
MIRT1456276	hsa-let-7i	CLIP-seq
MIRT1456277	hsa-miR-106a	CLIP-seq
MIRT1456278	hsa-miR-106b	CLIP-seq
MIRT1456279	hsa-miR-1236	CLIP-seq
MIRT1456280	hsa-miR-1245	CLIP-seq
MIRT1456281	hsa-miR-125a-5p	CLIP-seq
MIRT1456282	hsa-miR-125b	CLIP-seq
MIRT1456283	hsa-miR-1265	CLIP-seq
MIRT1456284	hsa-miR-1297	CLIP-seq
MIRT1456285	hsa-miR-1343	CLIP-seq
MIRT1456286	hsa-miR-142-5p	CLIP-seq
MIRT1456287	hsa-miR-17	CLIP-seq
MIRT1456288	hsa-miR-1825	CLIP-seq
MIRT1456289	hsa-miR-197	CLIP-seq
MIRT1456290	hsa-miR-2052	CLIP-seq
MIRT1456291	hsa-miR-20a	CLIP-seq
MIRT1456292	hsa-miR-20b	CLIP-seq
MIRT1456293	hsa-miR-216b	CLIP-seq
MIRT1456294	hsa-miR-23a	CLIP-seq
MIRT1456295	hsa-miR-23b	CLIP-seq
MIRT1456296	hsa-miR-23c	CLIP-seq
MIRT1456297	hsa-miR-24	CLIP-seq
MIRT1456298	hsa-miR-2682	CLIP-seq
MIRT1456299	hsa-miR-26a	CLIP-seq
MIRT1456300	hsa-miR-26b	CLIP-seq
MIRT1456301	hsa-miR-3074-5p	CLIP-seq
MIRT1456302	hsa-miR-3130-5p	CLIP-seq
MIRT1456303	hsa-miR-3148	CLIP-seq
MIRT1456304	hsa-miR-3150b-3p	CLIP-seq
MIRT1456305	hsa-miR-3157-3p	CLIP-seq
MIRT1456306	hsa-miR-3163	CLIP-seq
MIRT1456307	hsa-miR-3178	CLIP-seq
MIRT1456308	hsa-miR-3184	CLIP-seq
MIRT1456309	hsa-miR-3187-3p	CLIP-seq
MIRT1456310	hsa-miR-3192	CLIP-seq
MIRT1456311	hsa-miR-340	CLIP-seq
MIRT1456312	hsa-miR-3605-3p	CLIP-seq
MIRT1456313	hsa-miR-3605-5p	CLIP-seq
MIRT1456314	hsa-miR-3609	CLIP-seq
MIRT1456315	hsa-miR-3663-5p	CLIP-seq
MIRT1456316	hsa-miR-3689a-3p	CLIP-seq
MIRT1456317	hsa-miR-3689c	CLIP-seq
MIRT1456318	hsa-miR-3934	CLIP-seq
MIRT1456319	hsa-miR-3978	CLIP-seq
MIRT1456320	hsa-miR-410	CLIP-seq
MIRT1456321	hsa-miR-412	CLIP-seq
MIRT1456322	hsa-miR-423-5p	CLIP-seq
MIRT1456323	hsa-miR-4258	CLIP-seq
MIRT1456324	hsa-miR-4266	CLIP-seq
MIRT1456325	hsa-miR-4284	CLIP-seq
MIRT1456326	hsa-miR-4300	CLIP-seq
MIRT1456327	hsa-miR-4302	CLIP-seq
MIRT1456328	hsa-miR-4319	CLIP-seq
MIRT1456329	hsa-miR-4326	CLIP-seq
MIRT1456330	hsa-miR-4330	CLIP-seq
MIRT1456331	hsa-miR-4435	CLIP-seq
MIRT1456332	hsa-miR-4436b-3p	CLIP-seq
MIRT1456333	hsa-miR-4458	CLIP-seq
MIRT1456334	hsa-miR-4465	CLIP-seq
MIRT1456335	hsa-miR-4482	CLIP-seq
MIRT1456336	hsa-miR-449c	CLIP-seq
MIRT1456337	hsa-miR-4500	CLIP-seq
MIRT1456338	hsa-miR-4689	CLIP-seq
MIRT1456339	hsa-miR-4695-5p	CLIP-seq
MIRT1456340	hsa-miR-4701-5p	CLIP-seq
MIRT1456341	hsa-miR-4708-3p	CLIP-seq
MIRT1456342	hsa-miR-4709-3p	CLIP-seq
MIRT1456343	hsa-miR-4716-5p	CLIP-seq
MIRT1456344	hsa-miR-4726-3p	CLIP-seq
MIRT1456345	hsa-miR-4727-5p	CLIP-seq
MIRT1456346	hsa-miR-4728-5p	CLIP-seq
MIRT1456347	hsa-miR-4732-5p	CLIP-seq
MIRT1456348	hsa-miR-4737	CLIP-seq
MIRT1456349	hsa-miR-4755-3p	CLIP-seq
MIRT1456350	hsa-miR-4761-3p	CLIP-seq
MIRT1456351	hsa-miR-4761-5p	CLIP-seq
MIRT1456352	hsa-miR-4772-3p	CLIP-seq
MIRT1456353	hsa-miR-4779	CLIP-seq
MIRT1456354	hsa-miR-4781-3p	CLIP-seq
MIRT1456355	hsa-miR-4784	CLIP-seq
MIRT1456356	hsa-miR-4786-5p	CLIP-seq
MIRT1456357	hsa-miR-4796-3p	CLIP-seq
MIRT1456358	hsa-miR-483-5p	CLIP-seq
MIRT1456359	hsa-miR-5096	CLIP-seq
MIRT1456360	hsa-miR-519d	CLIP-seq
MIRT1456361	hsa-miR-544b	CLIP-seq
MIRT1456362	hsa-miR-548a-5p	CLIP-seq
MIRT1456363	hsa-miR-548ab	CLIP-seq
MIRT1456364	hsa-miR-548ah	CLIP-seq
MIRT1456365	hsa-miR-548ak	CLIP-seq
MIRT1456366	hsa-miR-548b-5p	CLIP-seq
MIRT1456367	hsa-miR-548c-3p	CLIP-seq
MIRT1456368	hsa-miR-548c-5p	CLIP-seq
MIRT1456369	hsa-miR-548d-5p	CLIP-seq
MIRT1456370	hsa-miR-548h	CLIP-seq
MIRT1456371	hsa-miR-548i	CLIP-seq
MIRT1456372	hsa-miR-548j	CLIP-seq
MIRT1456373	hsa-miR-548k	CLIP-seq
MIRT1456374	hsa-miR-548l	CLIP-seq
MIRT1456375	hsa-miR-548s	CLIP-seq
MIRT1456376	hsa-miR-548w	CLIP-seq
MIRT1456377	hsa-miR-548y	CLIP-seq
MIRT1456378	hsa-miR-558	CLIP-seq
MIRT1456379	hsa-miR-559	CLIP-seq
MIRT1456380	hsa-miR-588	CLIP-seq
MIRT1456381	hsa-miR-604	CLIP-seq
MIRT1456382	hsa-miR-647	CLIP-seq
MIRT1456383	hsa-miR-769-5p	CLIP-seq
MIRT1456384	hsa-miR-891b	CLIP-seq
MIRT1456385	hsa-miR-920	CLIP-seq
MIRT1456386	hsa-miR-93	CLIP-seq
MIRT1456387	hsa-miR-940	CLIP-seq
MIRT1456388	hsa-miR-942	CLIP-seq
MIRT1456389	hsa-miR-98	CLIP-seq
MIRT1456288	hsa-miR-1825	CLIP-seq
MIRT1456302	hsa-miR-3130-5p	CLIP-seq
MIRT1456307	hsa-miR-3178	CLIP-seq
MIRT1456308	hsa-miR-3184	CLIP-seq
MIRT1456322	hsa-miR-423-5p	CLIP-seq
MIRT1456330	hsa-miR-4330	CLIP-seq
MIRT1456335	hsa-miR-4482	CLIP-seq
MIRT1456348	hsa-miR-4737	CLIP-seq
MIRT1456390	hsa-miR-4282	CLIP-seq
MIRT1456310	hsa-miR-3192	CLIP-seq
MIRT1456312	hsa-miR-3605-3p	CLIP-seq
MIRT1456326	hsa-miR-4300	CLIP-seq
MIRT1456378	hsa-miR-558	CLIP-seq
MIRT1456385	hsa-miR-920	CLIP-seq
MIRT1456388	hsa-miR-942	CLIP-seq
MIRT2136797	hsa-miR-1182	CLIP-seq
MIRT1456353	hsa-miR-4779	CLIP-seq
MIRT2357585	hsa-miR-122	CLIP-seq
MIRT1456279	hsa-miR-1236	CLIP-seq
MIRT1456281	hsa-miR-125a-5p	CLIP-seq
MIRT1456282	hsa-miR-125b	CLIP-seq
MIRT1456284	hsa-miR-1297	CLIP-seq
MIRT1456285	hsa-miR-1343	CLIP-seq
MIRT2357586	hsa-miR-147	CLIP-seq
MIRT1456293	hsa-miR-216b	CLIP-seq
MIRT1456294	hsa-miR-23a	CLIP-seq
MIRT1456295	hsa-miR-23b	CLIP-seq
MIRT1456296	hsa-miR-23c	CLIP-seq
MIRT1456298	hsa-miR-2682	CLIP-seq
MIRT1456299	hsa-miR-26a	CLIP-seq
MIRT1456300	hsa-miR-26b	CLIP-seq
MIRT2357587	hsa-miR-3135b	CLIP-seq
MIRT1456304	hsa-miR-3150b-3p	CLIP-seq
MIRT1456305	hsa-miR-3157-3p	CLIP-seq
MIRT1456306	hsa-miR-3163	CLIP-seq
MIRT1456310	hsa-miR-3192	CLIP-seq
MIRT2357588	hsa-miR-3652	CLIP-seq
MIRT2357589	hsa-miR-377	CLIP-seq
MIRT1456320	hsa-miR-410	CLIP-seq
MIRT1456321	hsa-miR-412	CLIP-seq
MIRT1456326	hsa-miR-4300	CLIP-seq
MIRT1456328	hsa-miR-4319	CLIP-seq
MIRT1456330	hsa-miR-4330	CLIP-seq
MIRT2357590	hsa-miR-4430	CLIP-seq
MIRT2357591	hsa-miR-4438	CLIP-seq
MIRT1456334	hsa-miR-4465	CLIP-seq
MIRT1456336	hsa-miR-449c	CLIP-seq
MIRT2357592	hsa-miR-4634	CLIP-seq
MIRT1456338	hsa-miR-4689	CLIP-seq
MIRT2357593	hsa-miR-4711-3p	CLIP-seq
MIRT1456345	hsa-miR-4727-5p	CLIP-seq
MIRT1456353	hsa-miR-4779	CLIP-seq
MIRT1456355	hsa-miR-4784	CLIP-seq
MIRT2357594	hsa-miR-4793-5p	CLIP-seq
MIRT2357595	hsa-miR-496	CLIP-seq
MIRT2357596	hsa-miR-541	CLIP-seq
MIRT1456361	hsa-miR-544b	CLIP-seq
MIRT1456367	hsa-miR-548c-3p	CLIP-seq
MIRT1456378	hsa-miR-558	CLIP-seq
MIRT2357597	hsa-miR-644	CLIP-seq
MIRT1456384	hsa-miR-891b	CLIP-seq
MIRT1456385	hsa-miR-920	CLIP-seq
MIRT1456387	hsa-miR-940	CLIP-seq
MIRT2651263	hsa-miR-1200	CLIP-seq
MIRT2651264	hsa-miR-129-5p	CLIP-seq
MIRT1456284	hsa-miR-1297	CLIP-seq
MIRT1456285	hsa-miR-1343	CLIP-seq
MIRT2651265	hsa-miR-149	CLIP-seq
MIRT1456288	hsa-miR-1825	CLIP-seq
MIRT2651266	hsa-miR-1976	CLIP-seq
MIRT2651267	hsa-miR-2276	CLIP-seq
MIRT1456299	hsa-miR-26a	CLIP-seq
MIRT1456300	hsa-miR-26b	CLIP-seq
MIRT2651268	hsa-miR-3064-5p	CLIP-seq
MIRT1456302	hsa-miR-3130-5p	CLIP-seq
MIRT2651269	hsa-miR-3149	CLIP-seq
MIRT2651270	hsa-miR-3177-5p	CLIP-seq
MIRT1456307	hsa-miR-3178	CLIP-seq
MIRT1456308	hsa-miR-3184	CLIP-seq
MIRT2651271	hsa-miR-3545-3p	CLIP-seq
MIRT2651272	hsa-miR-3713	CLIP-seq
MIRT1456322	hsa-miR-423-5p	CLIP-seq
MIRT2651273	hsa-miR-4279	CLIP-seq
MIRT1456327	hsa-miR-4302	CLIP-seq
MIRT2651274	hsa-miR-4324	CLIP-seq
MIRT1456330	hsa-miR-4330	CLIP-seq
MIRT1456334	hsa-miR-4465	CLIP-seq
MIRT1456335	hsa-miR-4482	CLIP-seq
MIRT2651275	hsa-miR-4666-5p	CLIP-seq
MIRT2651276	hsa-miR-4722-3p	CLIP-seq
MIRT1456345	hsa-miR-4727-5p	CLIP-seq
MIRT2651277	hsa-miR-4735-5p	CLIP-seq
MIRT1456348	hsa-miR-4737	CLIP-seq
MIRT2651278	hsa-miR-4775	CLIP-seq
MIRT1456356	hsa-miR-4786-5p	CLIP-seq
MIRT2651279	hsa-miR-4794	CLIP-seq
MIRT2651280	hsa-miR-4800-3p	CLIP-seq
MIRT1456361	hsa-miR-544b	CLIP-seq
MIRT2651281	hsa-miR-590-3p	CLIP-seq
MIRT1456383	hsa-miR-769-5p	CLIP-seq
MIRT1456384	hsa-miR-891b	CLIP-seq
MIRT2651264	hsa-miR-129-5p	CLIP-seq
MIRT1456284	hsa-miR-1297	CLIP-seq
MIRT1456285	hsa-miR-1343	CLIP-seq
MIRT2651265	hsa-miR-149	CLIP-seq
MIRT2651266	hsa-miR-1976	CLIP-seq
MIRT1456299	hsa-miR-26a	CLIP-seq
MIRT1456300	hsa-miR-26b	CLIP-seq
MIRT2651268	hsa-miR-3064-5p	CLIP-seq
MIRT2651269	hsa-miR-3149	CLIP-seq
MIRT2694205	hsa-miR-411	CLIP-seq
MIRT2651273	hsa-miR-4279	CLIP-seq
MIRT1456334	hsa-miR-4465	CLIP-seq
MIRT2651276	hsa-miR-4722-3p	CLIP-seq
MIRT1456345	hsa-miR-4727-5p	CLIP-seq
MIRT2651277	hsa-miR-4735-5p	CLIP-seq
MIRT2651278	hsa-miR-4775	CLIP-seq
MIRT2651279	hsa-miR-4794	CLIP-seq
MIRT1456358	hsa-miR-483-5p	CLIP-seq
MIRT2651281	hsa-miR-590-3p	CLIP-seq
MIRT1456384	hsa-miR-891b	CLIP-seq

Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000781	Component	Chromosome, telomeric region	IEA
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	24692559
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007605	Process	Sensory perception of sound	IEA
GO:0015629	Component	Actin cytoskeleton	IBA
GO:0015629	Component	Actin cytoskeleton	IDA	11148140
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0015629	Component	Actin cytoskeleton	NAS	11148140
GO:0030047	Process	Actin modification	NAS	11148140
GO:0030496	Component	Midbody	IEA
GO:0031267	Function	Small GTPase binding	NAS	11148140
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	18194665
GO:0045159	Function	Myosin II binding	NAS	11148140
GO:0051015	Function	Actin filament binding	IBA
GO:0051015	Function	Actin filament binding	IDA	11148140
GO:0051016	Process	Barbed-end actin filament capping	NAS	11148140
GO:0051301	Process	Cell division	IEA
GO:0060088	Process	Auditory receptor cell stereocilium organization	IEA
GO:0120044	Component	Stereocilium base	IEA
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IBA
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IDA	11148140
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IEA

MIM	HGNC	e!Ensembl
609761	17009	ENSG00000100106

Q9H2D6

Protein name

TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)

Protein function

[Isoform 1]: Regulates actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin and prevents its depolymerization (PubMed:18194665, PubMed:28438837). May also serve as a linker

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00169	PH	1779 → 1887	PH domain	Domain

Tissue specificity

TISSUE SPECIFICITY: [Isoform 1]: Widely expressed. Highly expressed in heart and placenta. {ECO:0000269|PubMed:11148140}.; TISSUE SPECIFICITY: [Isoform 3]: Expressed in fetal brain, retina and cochlea but is not detectable in the other tissues. {ECO:00002

Sequence

MEEVPGDALCEHFEANILTQNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAP
EDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTT
SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE
GPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL
TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEIS
RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQ
QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSP
NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS
CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS
PNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTT
SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA
SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP
RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRT
SSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTK
RDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRT
NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDP
PQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH
RDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHT
QFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLP
RASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLA
PSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGE
TRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEA
AGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPE
KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPH
RHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTH
ELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWR
DLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTND
VPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG
LEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGS
PLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLT
TTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHT
KDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGE
QRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDLA
QRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRE
NKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGH
IPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIE
AMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALM
RQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSC
ELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIE
QLKEHLRLAMAALQEKESMRNSLAE

Sequence length

2365

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Autosomal recessive nonsyndromic hearing loss 28	Pathogenic; Likely pathogenic	rs768625959, rs1485334519, rs773152243, rs2145835560, rs369119867, rs371412957, rs1329127252, rs375857763, rs575123401, rs2145833313, rs118204026, rs118204027, rs118204028, rs118204029, rs118204030 View all (18 more)	RCV001337107 RCV001799527 RCV001822908 RCV001823265 RCV004820887 View all (28 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Hearing impairment	Likely pathogenic	rs756145453	RCV001375213	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Hearing loss, autosomal recessive	Pathogenic; Likely pathogenic	rs777561677, rs1569042782, rs771696726	RCV004719051 RCV001291492 RCV001291491	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Nonsyndromic genetic hearing loss	Pathogenic	rs118204027, rs727503528	RCV004017219 RCV000152152	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Rare genetic deafness	Pathogenic; Likely pathogenic	rs768625959, rs766809690, rs2518161108, rs1569034200, rs750078356	RCV004017820 RCV004017874 RCV004018188 RCV004018209 RCV004017663	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
TRIOBP-related disorder	Pathogenic; Likely pathogenic	rs745776539, rs2518225761, rs767529592	RCV003420587 RCV003397534 RCV003414262	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (31)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Adrenocortical carcinoma, hereditary	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTOSOMAL RECESSIVE ISOLATED SENSORINEURAL DEAFNESS TYPE DFNB	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Deafness	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, AUTOSOMAL RECESSIVE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, AUTOSOMAL RECESSIVE 28	—	CTD, Disgenet, HPO CTD, Disgenet, HPO CTD, Disgenet, HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEARING LOSS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign; Benign; Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Meniere disease	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
NEPHROLITHIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPEN-ANGLE GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SENSORINEURAL HEARING LOSS OF BILATERAL EARS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell lung carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRIOBP-related hearing loss	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (25)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Autosomal recessive non-syndromic sensorineural deafness type DFNB	Non-Syndromic Sensorineural Deafness	Orphanet			★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	32188867	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	38179759	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	28125788		★★★★★ ★☆☆☆☆ Found in Text Mining only
Deafness	Deafness	Pubtator	23226338, 25333879, 27344577, 29568747, 32487028, 35062939, 36029164, 39533558	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Deafness Autosomal Recessive	Deafness	Pubtator	29568747	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	Deafness	CLINGEN_DG	16385457, 16385458, 20510926, 23226338, 24853665, 27014650, 27344577, 27764096		★★★★★ ★☆☆☆☆ Found in Text Mining only
Deafness, Autosomal Recessive 28	Deafness	UNIPROT_DG	16385457, 16385458		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Deafness, Autosomal Recessive 28	Deafness	GENOMICS_ENGLAND_DG	20510926		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Deafness, Autosomal Recessive 28	Deafness	CLINVAR_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Deafness, Autosomal Recessive 28	Deafness	CTD_human_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	28736931		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	29363730		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	29363730	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	29363730		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29363730		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29363730	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hearing Loss	Hearing loss	Pubtator	29197352, 29363730, 32487028, 32682410, 35062939, 36029164	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hearing Loss Sensorineural	Hearing loss	Pubtator	29197352, 36029164	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29363730, 29890989		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nonsyndromic Deafness	Nonsyndromic Deafness	BEFREE	16385457, 16385458, 27764096, 29890989		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	37579195	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	Pubtator	25333879	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Skin Neoplasms	Skin neoplasm	Pubtator	32188867	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	26872740	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TRIOBP (TRIO and F-actin binding protein)