Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	11034
Gene name	Destrin, actin depolymerizing factor
Gene symbol	DSTN
Synonyms (NCBI Gene)	ACTDPADFHEL32bA462D18.2
Chromosome	20
Chromosome location	20p12.1
Summary	The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) an

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miRTarBase ID	miRNA	Experiments	Reference
MIRT041745	hsa-miR-484	CLASH	23622248
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT507529	hsa-miR-942-3p	PAR-CLIP	21572407
MIRT545615	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT329006	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	21572407
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	21572407
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	21572407
MIRT329015	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT507525	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT329008	hsa-miR-655-5p	PAR-CLIP	21572407
MIRT545614	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT545613	hsa-miR-6086	PAR-CLIP	21572407
MIRT545612	hsa-miR-4663	PAR-CLIP	21572407
MIRT545611	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT545610	hsa-miR-8077	PAR-CLIP	21572407
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT507518	hsa-miR-23c	PAR-CLIP	21572407
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	21572407
MIRT329009	hsa-miR-2054	PAR-CLIP	21572407
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	21572407
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT733526	hsa-miR-362-5p	Western blottingMicroarrayRNA-seq	34120636
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT507529	hsa-miR-942-3p	PAR-CLIP	21572407
MIRT545615	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT329006	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	21572407
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	21572407
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	21572407
MIRT329015	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT507525	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT329008	hsa-miR-655-5p	PAR-CLIP	21572407
MIRT545614	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT545613	hsa-miR-6086	PAR-CLIP	21572407
MIRT545612	hsa-miR-4663	PAR-CLIP	21572407
MIRT545611	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT545610	hsa-miR-8077	PAR-CLIP	21572407
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT507518	hsa-miR-23c	PAR-CLIP	21572407
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	21572407
MIRT329009	hsa-miR-2054	PAR-CLIP	21572407
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	21572407
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946302	hsa-miR-33a	CLIP-seq
MIRT946303	hsa-miR-33b	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946308	hsa-miR-4775	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT946312	hsa-miR-548a-3p	CLIP-seq
MIRT946313	hsa-miR-548e	CLIP-seq
MIRT946314	hsa-miR-548f	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT946316	hsa-miR-1323	CLIP-seq
MIRT946317	hsa-miR-3187-3p	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT946320	hsa-miR-3926	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946322	hsa-miR-4435	CLIP-seq
MIRT946323	hsa-miR-4652-3p	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT946324	hsa-miR-4701-5p	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT946308	hsa-miR-4775	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT946328	hsa-miR-548o	CLIP-seq
MIRT946329	hsa-miR-548s	CLIP-seq
MIRT946330	hsa-miR-588	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT946316	hsa-miR-1323	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT1980227	hsa-miR-1976	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT1980228	hsa-miR-3140-5p	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT946317	hsa-miR-3187-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT946320	hsa-miR-3926	CLIP-seq
MIRT1980234	hsa-miR-412	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1980235	hsa-miR-4279	CLIP-seq
MIRT946322	hsa-miR-4435	CLIP-seq
MIRT946324	hsa-miR-4701-5p	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT946328	hsa-miR-548o	CLIP-seq
MIRT946329	hsa-miR-548s	CLIP-seq
MIRT946330	hsa-miR-588	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT2215313	hsa-miR-1200	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215314	hsa-miR-1257	CLIP-seq
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215317	hsa-miR-140-3p	CLIP-seq
MIRT2215318	hsa-miR-151-3p	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT1980227	hsa-miR-1976	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT2215320	hsa-miR-299-3p	CLIP-seq
MIRT2215321	hsa-miR-3138	CLIP-seq
MIRT1980228	hsa-miR-3140-5p	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946302	hsa-miR-33a	CLIP-seq
MIRT946303	hsa-miR-33b	CLIP-seq
MIRT2215322	hsa-miR-340	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT2215323	hsa-miR-3685	CLIP-seq
MIRT2215324	hsa-miR-374a	CLIP-seq
MIRT2215325	hsa-miR-374b	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT2215326	hsa-miR-384	CLIP-seq
MIRT2215327	hsa-miR-3934	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT2215329	hsa-miR-3973	CLIP-seq
MIRT1980234	hsa-miR-412	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1980235	hsa-miR-4279	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2215330	hsa-miR-4324	CLIP-seq
MIRT2215331	hsa-miR-4453	CLIP-seq
MIRT2215332	hsa-miR-4491	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT2215334	hsa-miR-452	CLIP-seq
MIRT2215335	hsa-miR-4528	CLIP-seq
MIRT2215336	hsa-miR-4538	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215338	hsa-miR-4639-3p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2215340	hsa-miR-4657	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215342	hsa-miR-4666-3p	CLIP-seq
MIRT2215343	hsa-miR-4668-3p	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT2215346	hsa-miR-4755-3p	CLIP-seq
MIRT2215347	hsa-miR-4760-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215349	hsa-miR-4790-3p	CLIP-seq
MIRT2215350	hsa-miR-4800-5p	CLIP-seq
MIRT2215351	hsa-miR-4804-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT2215352	hsa-miR-544b	CLIP-seq
MIRT946312	hsa-miR-548a-3p	CLIP-seq
MIRT2215353	hsa-miR-548a-5p	CLIP-seq
MIRT2215354	hsa-miR-548ab	CLIP-seq
MIRT2215355	hsa-miR-548ak	CLIP-seq
MIRT2215356	hsa-miR-548b-5p	CLIP-seq
MIRT2215357	hsa-miR-548c-3p	CLIP-seq
MIRT2215358	hsa-miR-548c-5p	CLIP-seq
MIRT2215359	hsa-miR-548d-5p	CLIP-seq
MIRT946313	hsa-miR-548e	CLIP-seq
MIRT946314	hsa-miR-548f	CLIP-seq
MIRT2215360	hsa-miR-548h	CLIP-seq
MIRT2215361	hsa-miR-548i	CLIP-seq
MIRT2215362	hsa-miR-548j	CLIP-seq
MIRT2215363	hsa-miR-548p	CLIP-seq
MIRT2215364	hsa-miR-548w	CLIP-seq
MIRT2215365	hsa-miR-548y	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT2215367	hsa-miR-552	CLIP-seq
MIRT2215368	hsa-miR-559	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2215369	hsa-miR-668	CLIP-seq
MIRT2215370	hsa-miR-676	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215314	hsa-miR-1257	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT2519772	hsa-miR-186	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT2519773	hsa-miR-3133	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT2519774	hsa-miR-3529	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT2519775	hsa-miR-3619-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT2519776	hsa-miR-3688-5p	CLIP-seq
MIRT2519777	hsa-miR-379	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2519778	hsa-miR-4451	CLIP-seq
MIRT2519779	hsa-miR-4474-3p	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT2519780	hsa-miR-4520b-3p	CLIP-seq
MIRT2519781	hsa-miR-4529-3p	CLIP-seq
MIRT2519782	hsa-miR-4535	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215338	hsa-miR-4639-3p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2519783	hsa-miR-4650-3p	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT2215346	hsa-miR-4755-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT2519784	hsa-miR-4776-5p	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215349	hsa-miR-4790-3p	CLIP-seq
MIRT2519785	hsa-miR-4802-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2215369	hsa-miR-668	CLIP-seq
MIRT2519786	hsa-miR-671-5p	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT2519772	hsa-miR-186	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT2215320	hsa-miR-299-3p	CLIP-seq
MIRT2519773	hsa-miR-3133	CLIP-seq
MIRT2215321	hsa-miR-3138	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT2519774	hsa-miR-3529	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT2519775	hsa-miR-3619-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT2519776	hsa-miR-3688-5p	CLIP-seq
MIRT2519777	hsa-miR-379	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2519778	hsa-miR-4451	CLIP-seq
MIRT2519779	hsa-miR-4474-3p	CLIP-seq
MIRT2215332	hsa-miR-4491	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT2519780	hsa-miR-4520b-3p	CLIP-seq
MIRT2519781	hsa-miR-4529-3p	CLIP-seq
MIRT2519782	hsa-miR-4535	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2519783	hsa-miR-4650-3p	CLIP-seq
MIRT2215340	hsa-miR-4657	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT2519784	hsa-miR-4776-5p	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215350	hsa-miR-4800-5p	CLIP-seq
MIRT2519785	hsa-miR-4802-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2519786	hsa-miR-671-5p	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 26618866, 29892012, 29924966, 31324722, 31515488, 32296183, 35156780, 35271311
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0008154	Process	Actin polymerization or depolymerization	IEA
GO:0008154	Process	Actin polymerization or depolymerization	TAS	8399167
GO:0015629	Component	Actin cytoskeleton	IBA
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0015629	Component	Actin cytoskeleton	TAS	8399167
GO:0030042	Process	Actin filament depolymerization	IDA	11812157
GO:0030042	Process	Actin filament depolymerization	IEA
GO:0030043	Process	Actin filament fragmentation	IBA
GO:0030043	Process	Actin filament fragmentation	IEA
GO:0030836	Process	Positive regulation of actin filament depolymerization	IEA
GO:0030864	Component	Cortical actin cytoskeleton	IEA
GO:0048870	Process	Cell motility	IEA
GO:0051014	Process	Actin filament severing	IBA
GO:0051014	Process	Actin filament severing	TAS	8399167
GO:0051015	Function	Actin filament binding	IBA
GO:0051015	Function	Actin filament binding	IDA	8399167, 11812157
GO:0051015	Function	Actin filament binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0098793	Component	Presynapse	IEA
GO:0098794	Component	Postsynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA

MIM	HGNC	e!Ensembl
609114	15750	ENSG00000125868

P60981

Protein name

Destrin (Actin-depolymerizing factor) (ADF)

Protein function

Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00241	Cofilin_ADF	23 → 151	Cofilin/tropomyosin-type actin-binding protein	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely distributed in various tissues.

Sequence

MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV

Sequence length

165

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CONGESTIVE HEART FAILURE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART FAILURE	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENTRICULAR REMODELING	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (35)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult T-Cell Lymphoma/Leukemia	T-Cell Lymphoma/Leukemia	BEFREE	2999237		★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	17201177, 19143767		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial fibrillation	Pubtator	21736391	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	8639174		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29989053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	38292868	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic sinusitis	Sinusitis	BEFREE	25573836		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	17583572, 28358024		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	LHGDN	17583572		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28358024	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Complete atrioventricular block	Complete Atrioventricular Block	BEFREE	25800974		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	CTD_human_DG	29394407		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dejerine-Sottas Disease (disorder)	Charcot-Marie-Tooth disease	BEFREE	31355393		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fragile X Syndrome	Fragile X Syndrome	BEFREE	29114038		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	10455409, 17699103, 20528917, 26079827		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	10455409, 17699103, 20528917, 26079827, 29340013		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	7519632		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	CTD_human_DG	29394407		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Heart Failure, Right-Sided	Heart Failure	CTD_human_DG	29394407		★★★★★ ★☆☆☆☆ Found in Text Mining only
Left-Sided Heart Failure	Heart Failure	CTD_human_DG	29394407		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	3011152	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29989053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	22898637		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	19893039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	23374291		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22898637, 29340013		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	17583572, 28358024		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	17699103		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Failure	Myocardial Infarction	CTD_human_DG	29394407		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	29989053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	29115457	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	22898637		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	19893039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	39896807	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

DSTN (destrin, actin depolymerizing factor)