SEC24A (SEC24 homolog A, COPII component)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10802 |
| Gene name | SEC24 homolog A, COPII component |
| Gene symbol | SEC24A |
| Synonyms (NCBI Gene) |
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| Chromosome | 5 |
| Chromosome location | 5q31.1 |
| Summary | The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cy |
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miRNA
miRNA information provided by mirtarbase database.
619
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
31
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95486 | ||||||||||||||||||||||||||||||
| Protein name | Protein transport protein Sec24A (SEC24-related protein A) | ||||||||||||||||||||||||||||||
| Protein function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicle | ||||||||||||||||||||||||||||||
| PDB | 2NUP , 2NUT , 3EGD , 3EGX , 5VNE , 5VNF , 5VNG , 5VNH , 5VNI , 5VNJ , 5VNK , 5VNL , 5VNM , 5VNN , 5VNO , 8HR0 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1093 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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