HBS1L (HBS1 like translational GTPase)

Gene

• Entrez ID: 10767
• Gene name: HBS1 like translational GTPase
• Gene symbol: HBS1L
• Synonyms (NCBI Gene): EF-1a, ERFS, HBS1, HSPC276, eRF3c
• Chromosome: 6
• Chromosome location: 6q23.3
• Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitat

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028343	hsa-miR-32-5p	Sequencing	20371350
MIRT046986	hsa-miR-218-5p	CLASH	23622248
MIRT046078	hsa-miR-125b-5p	CLASH	23622248
MIRT038298	hsa-miR-130b-5p	CLASH	23622248
MIRT693268	hsa-miR-5003-3p	HITS-CLIP	23313552
MIRT693267	hsa-miR-7845-5p	HITS-CLIP	23313552
MIRT693266	hsa-miR-3126-5p	HITS-CLIP	23313552
MIRT693265	hsa-miR-6875-5p	HITS-CLIP	23313552
MIRT693264	hsa-miR-1249-5p	HITS-CLIP	23313552
MIRT693263	hsa-miR-6797-5p	HITS-CLIP	23313552
MIRT693262	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693261	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693260	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693259	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693258	hsa-miR-3175	HITS-CLIP	23313552
MIRT693257	hsa-miR-1343-5p	HITS-CLIP	23313552
MIRT693256	hsa-miR-939-5p	HITS-CLIP	23313552
MIRT693255	hsa-miR-6825-5p	HITS-CLIP	23313552
MIRT693254	hsa-miR-6740-5p	HITS-CLIP	23313552
MIRT693253	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT693252	hsa-miR-2110	HITS-CLIP	23313552
MIRT693251	hsa-miR-6810-5p	HITS-CLIP	23313552
MIRT693250	hsa-miR-3150a-3p	HITS-CLIP	23313552
MIRT693249	hsa-miR-6763-5p	HITS-CLIP	23313552
MIRT693248	hsa-miR-6857-5p	HITS-CLIP	23313552
MIRT693247	hsa-miR-5587-5p	HITS-CLIP	23313552
MIRT693246	hsa-miR-450a-2-3p	HITS-CLIP	23313552
MIRT693245	hsa-miR-4260	HITS-CLIP	23313552
MIRT693244	hsa-miR-5572	HITS-CLIP	23313552
MIRT693243	hsa-miR-4748	HITS-CLIP	23313552
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT625929	hsa-miR-6844	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT217793	hsa-miR-10a-3p	PAR-CLIP	22100165
MIRT446021	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446020	hsa-miR-26a-2-3p	PAR-CLIP	22100165
MIRT217793	hsa-miR-10a-3p	PAR-CLIP	22100165
MIRT446021	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446020	hsa-miR-26a-2-3p	PAR-CLIP	22100165
MIRT217788	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT217788	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	27418678
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	27418678
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	27418678
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	27418678
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	27418678
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	27418678
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	27418678
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	27418678
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	27418678
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	27418678
MIRT217789	hsa-miR-507	HITS-CLIP	27418678
MIRT217789	hsa-miR-507	HITS-CLIP	27418678
MIRT217791	hsa-miR-557	HITS-CLIP	27418678
MIRT217791	hsa-miR-557	HITS-CLIP	27418678
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	27418678
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	27418678
MIRT693268	hsa-miR-5003-3p	HITS-CLIP	23313552
MIRT693267	hsa-miR-7845-5p	HITS-CLIP	23313552
MIRT693266	hsa-miR-3126-5p	HITS-CLIP	23313552
MIRT693265	hsa-miR-6875-5p	HITS-CLIP	23313552
MIRT693264	hsa-miR-1249-5p	HITS-CLIP	23313552
MIRT693263	hsa-miR-6797-5p	HITS-CLIP	23313552
MIRT693262	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693261	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693260	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693259	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693258	hsa-miR-3175	HITS-CLIP	23313552
MIRT693257	hsa-miR-1343-5p	HITS-CLIP	23313552
MIRT693256	hsa-miR-939-5p	HITS-CLIP	23313552
MIRT693255	hsa-miR-6825-5p	HITS-CLIP	23313552
MIRT693254	hsa-miR-6740-5p	HITS-CLIP	23313552
MIRT693253	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT693252	hsa-miR-2110	HITS-CLIP	23313552
MIRT693251	hsa-miR-6810-5p	HITS-CLIP	23313552
MIRT693250	hsa-miR-3150a-3p	HITS-CLIP	23313552
MIRT693249	hsa-miR-6763-5p	HITS-CLIP	23313552
MIRT693248	hsa-miR-6857-5p	HITS-CLIP	23313552
MIRT693247	hsa-miR-5587-5p	HITS-CLIP	23313552
MIRT693246	hsa-miR-450a-2-3p	HITS-CLIP	23313552
MIRT693245	hsa-miR-4260	HITS-CLIP	23313552
MIRT693244	hsa-miR-5572	HITS-CLIP	23313552
MIRT693243	hsa-miR-4748	HITS-CLIP	23313552
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT625929	hsa-miR-6844	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615654	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615653	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT615652	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT615651	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT217789	hsa-miR-507	HITS-CLIP	23824327
MIRT217791	hsa-miR-557	HITS-CLIP	23824327
MIRT615650	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT615649	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT217788	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT217793	hsa-miR-10a-3p	PAR-CLIP	22100165
MIRT446021	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446020	hsa-miR-26a-2-3p	PAR-CLIP	22100165
MIRT217793	hsa-miR-10a-3p	PAR-CLIP	22100165
MIRT446021	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446020	hsa-miR-26a-2-3p	PAR-CLIP	22100165
MIRT1041543	hsa-miR-208a	CLIP-seq
MIRT1041544	hsa-miR-208b	CLIP-seq
MIRT1041545	hsa-miR-4432	CLIP-seq
MIRT1041546	hsa-miR-4477a	CLIP-seq
MIRT1041547	hsa-miR-4690-3p	CLIP-seq
MIRT1041548	hsa-miR-499-5p	CLIP-seq
MIRT1041549	hsa-miR-130a	CLIP-seq
MIRT1041550	hsa-miR-130b	CLIP-seq
MIRT1041551	hsa-miR-148a	CLIP-seq
MIRT1041552	hsa-miR-148b	CLIP-seq
MIRT1041553	hsa-miR-152	CLIP-seq
MIRT1041554	hsa-miR-154	CLIP-seq
MIRT1041555	hsa-miR-19a	CLIP-seq
MIRT1041556	hsa-miR-19b	CLIP-seq
MIRT1041557	hsa-miR-301a	CLIP-seq
MIRT1041558	hsa-miR-301b	CLIP-seq
MIRT1041559	hsa-miR-30a	CLIP-seq
MIRT1041560	hsa-miR-30b	CLIP-seq
MIRT1041561	hsa-miR-30c	CLIP-seq
MIRT1041562	hsa-miR-30d	CLIP-seq
MIRT1041563	hsa-miR-30e	CLIP-seq
MIRT1041564	hsa-miR-3129-3p	CLIP-seq
MIRT738570	hsa-miR-34c-3p	CLIP-seq
MIRT1041565	hsa-miR-3617	CLIP-seq
MIRT1041566	hsa-miR-3666	CLIP-seq
MIRT1041567	hsa-miR-3920	CLIP-seq
MIRT1041568	hsa-miR-4281	CLIP-seq
MIRT1041569	hsa-miR-4295	CLIP-seq
MIRT738569	hsa-miR-4420	CLIP-seq
MIRT1041570	hsa-miR-4436b-5p	CLIP-seq
MIRT1041571	hsa-miR-454	CLIP-seq
MIRT738572	hsa-miR-4676-5p	CLIP-seq
MIRT738568	hsa-miR-4766-5p	CLIP-seq
MIRT1041572	hsa-miR-4795-3p	CLIP-seq
MIRT1041573	hsa-miR-4797-3p	CLIP-seq
MIRT1041574	hsa-miR-4802-3p	CLIP-seq
MIRT1041575	hsa-miR-510	CLIP-seq
MIRT1041576	hsa-miR-512-5p	CLIP-seq
MIRT1041577	hsa-miR-513b	CLIP-seq
MIRT1041578	hsa-miR-548c-3p	CLIP-seq
MIRT738571	hsa-miR-575	CLIP-seq
MIRT1041579	hsa-miR-579	CLIP-seq
MIRT1041580	hsa-miR-587	CLIP-seq
MIRT1041581	hsa-miR-641	CLIP-seq
MIRT738570	hsa-miR-34c-3p	CLIP-seq
MIRT738569	hsa-miR-4420	CLIP-seq
MIRT738572	hsa-miR-4676-5p	CLIP-seq
MIRT738568	hsa-miR-4766-5p	CLIP-seq
MIRT738571	hsa-miR-575	CLIP-seq
MIRT2008714	hsa-miR-101	CLIP-seq
MIRT2008715	hsa-miR-302a	CLIP-seq
MIRT2008716	hsa-miR-302b	CLIP-seq
MIRT2008717	hsa-miR-302c	CLIP-seq
MIRT2008718	hsa-miR-302d	CLIP-seq
MIRT2008719	hsa-miR-302e	CLIP-seq
MIRT738570	hsa-miR-34c-3p	CLIP-seq
MIRT1041565	hsa-miR-3617	CLIP-seq
MIRT2008720	hsa-miR-369-3p	CLIP-seq
MIRT2008721	hsa-miR-371-5p	CLIP-seq
MIRT2008722	hsa-miR-371b-5p	CLIP-seq
MIRT2008723	hsa-miR-372	CLIP-seq
MIRT2008724	hsa-miR-373	CLIP-seq
MIRT2008725	hsa-miR-374a	CLIP-seq
MIRT2008726	hsa-miR-374b	CLIP-seq
MIRT738569	hsa-miR-4420	CLIP-seq
MIRT738572	hsa-miR-4676-5p	CLIP-seq
MIRT2008727	hsa-miR-4733-5p	CLIP-seq
MIRT738568	hsa-miR-4766-5p	CLIP-seq
MIRT2008728	hsa-miR-512-3p	CLIP-seq
MIRT2008729	hsa-miR-520a-3p	CLIP-seq
MIRT2008730	hsa-miR-520b	CLIP-seq
MIRT2008731	hsa-miR-520c-3p	CLIP-seq
MIRT2008732	hsa-miR-520d-3p	CLIP-seq
MIRT2008733	hsa-miR-520e	CLIP-seq
MIRT738571	hsa-miR-575	CLIP-seq
MIRT1041581	hsa-miR-641	CLIP-seq
MIRT2008714	hsa-miR-101	CLIP-seq
MIRT1041554	hsa-miR-154	CLIP-seq
MIRT1041559	hsa-miR-30a	CLIP-seq
MIRT1041560	hsa-miR-30b	CLIP-seq
MIRT1041561	hsa-miR-30c	CLIP-seq
MIRT1041562	hsa-miR-30d	CLIP-seq
MIRT1041563	hsa-miR-30e	CLIP-seq
MIRT2008721	hsa-miR-371-5p	CLIP-seq
MIRT2008722	hsa-miR-371b-5p	CLIP-seq
MIRT2241166	hsa-miR-409-5p	CLIP-seq
MIRT1041570	hsa-miR-4436b-5p	CLIP-seq
MIRT1041573	hsa-miR-4797-3p	CLIP-seq
MIRT1041575	hsa-miR-510	CLIP-seq
MIRT1041576	hsa-miR-512-5p	CLIP-seq
MIRT1041580	hsa-miR-587	CLIP-seq
MIRT2544704	hsa-miR-1179	CLIP-seq
MIRT2544705	hsa-miR-1184	CLIP-seq
MIRT2544706	hsa-miR-1202	CLIP-seq
MIRT2544707	hsa-miR-1208	CLIP-seq
MIRT2544708	hsa-miR-1301	CLIP-seq
MIRT2544709	hsa-miR-1343	CLIP-seq
MIRT2544710	hsa-miR-151-3p	CLIP-seq
MIRT2544711	hsa-miR-182	CLIP-seq
MIRT2544712	hsa-miR-197	CLIP-seq
MIRT2544713	hsa-miR-200b	CLIP-seq
MIRT2544714	hsa-miR-200c	CLIP-seq
MIRT2544715	hsa-miR-2355-5p	CLIP-seq
MIRT2544716	hsa-miR-24	CLIP-seq
MIRT2544717	hsa-miR-2467-3p	CLIP-seq
MIRT2544718	hsa-miR-2681	CLIP-seq
MIRT2544719	hsa-miR-3117-5p	CLIP-seq
MIRT2544720	hsa-miR-3143	CLIP-seq
MIRT2544721	hsa-miR-3678-3p	CLIP-seq
MIRT2544722	hsa-miR-3682-5p	CLIP-seq
MIRT2544723	hsa-miR-3713	CLIP-seq
MIRT2544724	hsa-miR-374c	CLIP-seq
MIRT2544725	hsa-miR-382	CLIP-seq
MIRT2544726	hsa-miR-3972	CLIP-seq
MIRT2544727	hsa-miR-3973	CLIP-seq
MIRT2544728	hsa-miR-4257	CLIP-seq
MIRT2544729	hsa-miR-4284	CLIP-seq
MIRT2544730	hsa-miR-429	CLIP-seq
MIRT2544731	hsa-miR-4418	CLIP-seq
MIRT738569	hsa-miR-4420	CLIP-seq
MIRT2544732	hsa-miR-4457	CLIP-seq
MIRT1041546	hsa-miR-4477a	CLIP-seq
MIRT2544733	hsa-miR-4659a-5p	CLIP-seq
MIRT2544734	hsa-miR-4659b-5p	CLIP-seq
MIRT2544735	hsa-miR-4660	CLIP-seq
MIRT2544736	hsa-miR-4715-5p	CLIP-seq
MIRT2544737	hsa-miR-4729	CLIP-seq
MIRT2544738	hsa-miR-4762-5p	CLIP-seq
MIRT2544739	hsa-miR-4766-3p	CLIP-seq
MIRT2544740	hsa-miR-4776-3p	CLIP-seq
MIRT1041572	hsa-miR-4795-3p	CLIP-seq
MIRT2544741	hsa-miR-494	CLIP-seq
MIRT2544742	hsa-miR-5047	CLIP-seq
MIRT2544743	hsa-miR-509-3-5p	CLIP-seq
MIRT2544744	hsa-miR-509-5p	CLIP-seq
MIRT1041577	hsa-miR-513b	CLIP-seq
MIRT2544745	hsa-miR-543	CLIP-seq
MIRT2544746	hsa-miR-548a-5p	CLIP-seq
MIRT2544747	hsa-miR-548ab	CLIP-seq
MIRT2544748	hsa-miR-548ak	CLIP-seq
MIRT2544749	hsa-miR-548an	CLIP-seq
MIRT2544750	hsa-miR-548b-5p	CLIP-seq
MIRT2544751	hsa-miR-548c-5p	CLIP-seq
MIRT2544752	hsa-miR-548d-5p	CLIP-seq
MIRT2544753	hsa-miR-548h	CLIP-seq
MIRT2544754	hsa-miR-548i	CLIP-seq
MIRT2544755	hsa-miR-548j	CLIP-seq
MIRT2544756	hsa-miR-548p	CLIP-seq
MIRT2544757	hsa-miR-548w	CLIP-seq
MIRT2544758	hsa-miR-548y	CLIP-seq
MIRT2544759	hsa-miR-559	CLIP-seq
MIRT2544760	hsa-miR-584	CLIP-seq
MIRT2544761	hsa-miR-605	CLIP-seq
MIRT2544762	hsa-miR-607	CLIP-seq
MIRT2544763	hsa-miR-655	CLIP-seq
MIRT2544764	hsa-miR-891b	CLIP-seq
MIRT2544765	hsa-miR-939	CLIP-seq
MIRT2544705	hsa-miR-1184	CLIP-seq
MIRT2544706	hsa-miR-1202	CLIP-seq
MIRT2544707	hsa-miR-1208	CLIP-seq
MIRT2544708	hsa-miR-1301	CLIP-seq
MIRT2544710	hsa-miR-151-3p	CLIP-seq
MIRT2544711	hsa-miR-182	CLIP-seq
MIRT2544712	hsa-miR-197	CLIP-seq
MIRT2544713	hsa-miR-200b	CLIP-seq
MIRT2544714	hsa-miR-200c	CLIP-seq
MIRT2544716	hsa-miR-24	CLIP-seq
MIRT2544717	hsa-miR-2467-3p	CLIP-seq
MIRT2544718	hsa-miR-2681	CLIP-seq
MIRT2544719	hsa-miR-3117-5p	CLIP-seq
MIRT2544720	hsa-miR-3143	CLIP-seq
MIRT2544721	hsa-miR-3678-3p	CLIP-seq
MIRT2544722	hsa-miR-3682-5p	CLIP-seq
MIRT2544724	hsa-miR-374c	CLIP-seq
MIRT2544725	hsa-miR-382	CLIP-seq
MIRT2544726	hsa-miR-3972	CLIP-seq
MIRT2544727	hsa-miR-3973	CLIP-seq
MIRT2544728	hsa-miR-4257	CLIP-seq
MIRT2544729	hsa-miR-4284	CLIP-seq
MIRT2544730	hsa-miR-429	CLIP-seq
MIRT2544731	hsa-miR-4418	CLIP-seq
MIRT738569	hsa-miR-4420	CLIP-seq
MIRT2544732	hsa-miR-4457	CLIP-seq
MIRT1041546	hsa-miR-4477a	CLIP-seq
MIRT2544733	hsa-miR-4659a-5p	CLIP-seq
MIRT2544734	hsa-miR-4659b-5p	CLIP-seq
MIRT2544735	hsa-miR-4660	CLIP-seq
MIRT2544736	hsa-miR-4715-5p	CLIP-seq
MIRT2544737	hsa-miR-4729	CLIP-seq
MIRT2544739	hsa-miR-4766-3p	CLIP-seq
MIRT2544740	hsa-miR-4776-3p	CLIP-seq
MIRT1041572	hsa-miR-4795-3p	CLIP-seq
MIRT2544741	hsa-miR-494	CLIP-seq
MIRT2544742	hsa-miR-5047	CLIP-seq
MIRT2544743	hsa-miR-509-3-5p	CLIP-seq
MIRT2544744	hsa-miR-509-5p	CLIP-seq
MIRT1041577	hsa-miR-513b	CLIP-seq
MIRT2544745	hsa-miR-543	CLIP-seq
MIRT2544746	hsa-miR-548a-5p	CLIP-seq
MIRT2544747	hsa-miR-548ab	CLIP-seq
MIRT2544748	hsa-miR-548ak	CLIP-seq
MIRT2544749	hsa-miR-548an	CLIP-seq
MIRT2544750	hsa-miR-548b-5p	CLIP-seq
MIRT2544751	hsa-miR-548c-5p	CLIP-seq
MIRT2544752	hsa-miR-548d-5p	CLIP-seq
MIRT2544753	hsa-miR-548h	CLIP-seq
MIRT2544754	hsa-miR-548i	CLIP-seq
MIRT2544755	hsa-miR-548j	CLIP-seq
MIRT2544756	hsa-miR-548p	CLIP-seq
MIRT2544757	hsa-miR-548w	CLIP-seq
MIRT2544758	hsa-miR-548y	CLIP-seq
MIRT2544759	hsa-miR-559	CLIP-seq
MIRT2544760	hsa-miR-584	CLIP-seq
MIRT2544761	hsa-miR-605	CLIP-seq
MIRT2544762	hsa-miR-607	CLIP-seq
MIRT2544763	hsa-miR-655	CLIP-seq
MIRT2544764	hsa-miR-891b	CLIP-seq
MIRT2544765	hsa-miR-939	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003746	Function	Translation elongation factor activity	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IEA
GO:0003924	Function	GTPase activity	ISS	20947765
GO:0005515	Function	Protein binding	IPI	20531386, 31515488, 32296183, 33961781
GO:0005525	Function	GTP binding	IEA
GO:0005525	Function	GTP binding	TAS	9872408
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006412	Process	Translation	IBA
GO:0006412	Process	Translation	IEA
GO:0006412	Process	Translation	TAS	9872408
GO:0006414	Process	Translational elongation	IEA
GO:0006417	Process	Regulation of translation	IEA
GO:0007165	Process	Signal transduction	TAS	9872408
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016787	Function	Hydrolase activity	IEA
GO:0022626	Component	Cytosolic ribosome	IDA	27863242
GO:0032790	Process	Ribosome disassembly	IDA	21448132
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0070966	Process	Nuclear-transcribed mRNA catabolic process, no-go decay	IDA	23667253, 27863242
GO:0072344	Process	Rescue of stalled ribosome	IDA	21448132, 27863242
GO:1990533	Component	Dom34-Hbs1 complex	IDA	27863242

Other IDs

• MIM: 612450
• HGNC: 4834
• e!Ensembl: ENSG00000112339

Protein

• UniProt ID: Q9Y450
• Protein name: HBS1-like protein (EC 3.6.5.-) (ERFS)
• Protein function: GTPase component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway (PubMed:21448132, PubMed:23667253, PubMed:27863242). The Pelota-HBS1L complex recognizes ribosomes stalled at th
• PDB: 5LZW, 5LZX, 5LZY, 5LZZ, 9G8M, 9G8N, 9G8O, 9G8P, 9G8R
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08938	HBS1_N	41 → 129	HBS1 N-terminus	Domain
  PF00009	GTP_EFTU	258 → 487	Elongation factor Tu GTP binding domain	Domain
  PF03144	GTP_EFTU_D2	502 → 569	Elongation factor Tu domain 2	Domain
  PF03143	GTP_EFTU_D3	574 → 683	Elongation factor Tu C-terminal domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in heart, brain, placenta, liver, muscle, kidney and pancreas. {ECO:0000269|PubMed:9872408}.
• Sequence:

  MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED
  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
  EQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPG
  VSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGK
  LRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESK
  KAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAA
  QADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQE
  ITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPP
  QRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP
  VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPV
  LLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFK
  ELGRFMLRYGGSTIAAGVVTEIKE

• Sequence length: 684

Pathways

KEGG:

mRNA surveillance pathway
Legionellosis

Reactome:

mRNA decay by 3' to 5' exoribonuclease

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANDROGENETIC ALOPECIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BENIGN PROSTATIC HYPERPLASIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BETA THALASSEMIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLONAL HEMATOPOIESIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEFICIENCY ANEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEMATOLOGIC DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEMOGLOBIN E DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEMORRHAGIC DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HODGKINS LYMPHOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERLIPIDEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTHYROIDISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE MYELOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYELOPROLIFERATIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
THROMBOCYTOPENIA 4	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
alpha-Thalassemia	alpha Thalassemia	BEFREE	19696200, 23606168, 24581976		★☆☆☆☆ Found in Text Mining only
alpha^+^ Thalassemia	alpha Thalassemia	BEFREE	19696200, 23606168, 24581976		★☆☆☆☆ Found in Text Mining only
Anemia Hemolytic	Hemolytic anemia	Pubtator	29879141	Associate	★☆☆☆☆ Found in Text Mining only
Anemia Sickle Cell	Sickle cell anemia	Pubtator	18667698, 21068433, 24667352, 25084696, 25928412, 28280727, 28332727, 29879141, 38339995	Associate	★☆☆☆☆ Found in Text Mining only
Anemia, Sickle Cell	Anemia	BEFREE	19148297, 20472475, 21057501, 25084696, 25928412, 28332727, 29879141, 30216683		★☆☆☆☆ Found in Text Mining only
Benign Prostatic Hyperplasia	Benign Prostatic Hyperplasia	BEFREE	29441592		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
beta Thalassemia	beta Thalassemia	BEFREE	18697826, 20472475		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
beta Thalassemia	Beta thalassemia	Pubtator	19696200, 21068433, 21385855, 22271886, 26771086, 27009595, 28280727	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Beta thalassemia intermedia	beta Thalassemia	BEFREE	20472475		★☆☆☆☆ Found in Text Mining only
beta^+^ Thalassemia	beta Thalassemia	BEFREE	18697826, 20472475		★☆☆☆☆ Found in Text Mining only
beta^0^ Thalassemia	beta Thalassemia	BEFREE	18839276		★☆☆☆☆ Found in Text Mining only
Chronic myeloproliferative disorder	Myeloproliferative disorder	BEFREE	29047144		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34537824	Associate	★☆☆☆☆ Found in Text Mining only
Congenital anomaly of face	Facial dysmorphism	BEFREE	30707697		★☆☆☆☆ Found in Text Mining only
Eosinophilic esophagitis	Eosinophilia	BEFREE	24581976		★☆☆☆☆ Found in Text Mining only
Ethylmalonic encephalopathy	Ethylmalonic Encephalopathy	BEFREE	24581976		★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	BEFREE	30707697		★☆☆☆☆ Found in Text Mining only
Glycogen Storage Disease 0 Muscle	Glycogen storage disease	Pubtator	26771086	Associate	★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	GWASCAT_DG	24149102		★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	GWASDB_DG	24149102		★☆☆☆☆ Found in Text Mining only
Kidney Failure	Kidney Failure	BEFREE	25915923		★☆☆☆☆ Found in Text Mining only
Myeloproliferative disease	Myeloproliferative disorder	BEFREE	25849990, 29100304		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	32998774	Associate	★☆☆☆☆ Found in Text Mining only
Polycythemia Vera	Polycythemia Vera	BEFREE	25849990		★☆☆☆☆ Found in Text Mining only
Spinocerebellar Ataxia 11	Spinocerebellar ataxia	Pubtator	24667352, 25084696	Associate	★☆☆☆☆ Found in Text Mining only
Thalassemia	Thalassemia	Pubtator	33990643, 36888630	Associate	★☆☆☆☆ Found in Text Mining only
Thrombocythemia Essential	Essential thrombocythemia	Pubtator	29047144	Associate	★☆☆☆☆ Found in Text Mining only
Thrombocythemia, Essential	Thrombocythemia	BEFREE	25849990, 29047144		★☆☆☆☆ Found in Text Mining only