RFPL2 (ret finger protein like 2)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 10739
Gene name Ret finger protein like 2
Gene symbol RFPL2
Synonyms (NCBI Gene)
RNF79
Chromosome 22
Chromosome location 22q12.3
miRNA miRNA information provided by mirtarbase database.
8
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (8)
miRTarBase ID miRNA Experiments Reference
MIRT2089596 hsa-miR-298 CLIP-seq
MIRT2089597 hsa-miR-3678-3p CLIP-seq
MIRT2089598 hsa-miR-548n CLIP-seq
MIRT2314555 hsa-miR-155 CLIP-seq
MIRT2314556 hsa-miR-3149 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0008270 Function Zinc ion binding IEA
GO:0010468 Process Regulation of gene expression IBA
GO:0045087 Process Innate immune response IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
605969 9979 ENSG00000128253
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75678
Protein name Ret finger protein-like 2 (RING finger protein 79)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15227 zf-C3HC4_4 101 → 142 Domain
PF11002 RDM 144 → 185 RFPL defining motif (RDM) Domain
PF13765 PRY 188 → 236 SPRY-associated domain Family
PF00622 SPRY 240 → 357 SPRY domain Family
Tissue specificity TISSUE SPECIFICITY: Seems to be expressed in prostate and less abundantly in adult brain, fetal liver, and fetal kidney.
Sequence
Sequence length 378
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (3)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
OLIGODENDROGLIOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
POLYCYSTIC OVARY SYNDROME — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations