SCGB1D1 (secretoglobin family 1D member 1)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 10648
Gene name Secretoglobin family 1D member 1
Gene symbol SCGB1D1
Synonyms (NCBI Gene)
LIPALPHALPNA
Chromosome 11
Chromosome location 11q12.3
Summary The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component
miRNA miRNA information provided by mirtarbase database.
13
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (13)
miRTarBase ID miRNA Experiments Reference
MIRT017463 hsa-miR-335-5p Microarray 18185580
MIRT029266 hsa-miR-26b-5p Microarray 19088304
MIRT2321896 hsa-miR-1184 CLIP-seq
MIRT2321897 hsa-miR-1205 CLIP-seq
MIRT2321898 hsa-miR-181a CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (6)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 9720917, 32296183
GO:0005576 Component Extracellular region IEA
GO:0005615 Component Extracellular space HDA 22664934, 23580065
GO:0005615 Component Extracellular space IBA
GO:0005615 Component Extracellular space IDA 9720917
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
615060 18395 ENSG00000168515
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95968
Protein name Secretoglobin family 1D member 1 (Lipophilin-A)
Protein function May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01099 Uteroglobin 1 → 88 Uteroglobin family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in lachrymal gland, thymus, kidney, testis, ovary and salivary gland.
Sequence
Sequence length 90
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
EOSINOPHILIC ESOPHAGITIS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LEPROSY — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (129)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acid cholesteryl ester hydrolase deficiency, type 2 Wolman disease GENOMICS_ENGLAND_DG 12666227, 8254026
★★★★★
★☆☆☆☆
Found in Text Mining only
Acid cholesteryl ester hydrolase deficiency, type 2 Wolman disease BEFREE 25624737, 26350820, 27423329, 27878737, 28197978, 28285817, 28502505, 28538091, 28881270, 29339442, 29547398, 30315827, 30540705, 30684275, 30866656
View all (7 more)
★★★★★
★☆☆☆☆
Found in Text Mining only
Acid cholesteryl ester hydrolase deficiency, type 2 Wolman disease CTD_human_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 26618658
★★★★★
★☆☆☆☆
Found in Text Mining only
Adrenal calcification Adrenal calcification HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Adult Acute Lymphocytic Leukemia Lymphocytic Leukemia BEFREE 26618658
★★★★★
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Alzheimer disease Pubtator 26433351 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Alzheimer disease, familial, type 3 Alzheimer disease BEFREE 16730122
★★★★★
★☆☆☆☆
Found in Text Mining only
Anal carcinoma Anal Cancer BEFREE 31641354
★★★★★
★☆☆☆☆
Found in Text Mining only
Anemia Anemia HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only