IPO7 (importin 7)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10527 |
| Gene name | Importin 7 |
| Gene symbol | IPO7 |
| Synonyms (NCBI Gene) |
Imp7RANBP7
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| Chromosome | 11 |
| Chromosome location | 11p15.4 |
| Summary | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence mot |
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miRNA
miRNA information provided by mirtarbase database.
895
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
2
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95373 | |||||||||||||||
| Protein name | Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7) | |||||||||||||||
| Protein function | Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuc | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1038 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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