Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10498
Gene name	Coactivator associated arginine methyltransferase 1
Gene symbol	CARM1
Synonyms (NCBI Gene)	PRMT4
Chromosome	19
Chromosome location	19p13.2
Summary	This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated protein

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miRTarBase ID	miRNA	Experiments	Reference
MIRT051469	hsa-let-7e-5p	CLASH	23622248
MIRT049639	hsa-miR-92a-3p	CLASH	23622248
MIRT054424	hsa-miR-15a-5p	Luciferase reporter assayqRT-PCRWestern blot	24530761
MIRT054424	hsa-miR-15a-5p	Luciferase reporter assayqRT-PCRWestern blot	24530761
MIRT054424	hsa-miR-15a-5p	Luciferase reporter assayqRT-PCRWestern blot	24530761
MIRT054424	hsa-miR-15a-5p	Luciferase reporter assayqRT-PCRWestern blot	24530761
MIRT438169	hsa-miR-223-3p	ChIP-seqFlowLuciferase reporter assayqRT-PCRWestern blot	24332853
MIRT438169	hsa-miR-223-3p	ChIP-seqFlowLuciferase reporter assayqRT-PCRWestern blot	24332853
MIRT149503	hsa-miR-6757-5p	PAR-CLIP	23592263
MIRT149479	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT149509	hsa-miR-7112-5p	PAR-CLIP	23592263
MIRT149408	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT149440	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT149491	hsa-miR-5093	PAR-CLIP	23592263
MIRT149470	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT149505	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT149405	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT149432	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT149384	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT149428	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT149445	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT149455	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT149500	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT081041	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT081042	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT081043	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT081049	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT149461	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT149464	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT149405	hsa-miR-1207-5p	PAR-CLIP	27292025
MIRT054424	hsa-miR-15a-5p	PAR-CLIP	27292025
MIRT149408	hsa-miR-1909-3p	PAR-CLIP	27292025
MIRT149432	hsa-miR-4763-3p	PAR-CLIP	27292025
MIRT149440	hsa-miR-6722-3p	PAR-CLIP	27292025
MIRT149503	hsa-miR-6757-5p	PAR-CLIP	23592263
MIRT149479	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT149509	hsa-miR-7112-5p	PAR-CLIP	23592263
MIRT149408	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT149440	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT149491	hsa-miR-5093	PAR-CLIP	23592263
MIRT149470	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT149505	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT149405	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT149432	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT149384	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT149428	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT149445	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT149455	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT149500	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT862958	hsa-miR-1182	CLIP-seq
MIRT862959	hsa-miR-1205	CLIP-seq
MIRT862960	hsa-miR-1234	CLIP-seq
MIRT862961	hsa-miR-1245b-3p	CLIP-seq
MIRT862962	hsa-miR-1260	CLIP-seq
MIRT862963	hsa-miR-1260b	CLIP-seq
MIRT862964	hsa-miR-128	CLIP-seq
MIRT862965	hsa-miR-1283	CLIP-seq
MIRT862966	hsa-miR-1294	CLIP-seq
MIRT862967	hsa-miR-129-5p	CLIP-seq
MIRT862968	hsa-miR-1297	CLIP-seq
MIRT862969	hsa-miR-15a	CLIP-seq
MIRT862970	hsa-miR-15b	CLIP-seq
MIRT862971	hsa-miR-16	CLIP-seq
MIRT862972	hsa-miR-181a	CLIP-seq
MIRT862973	hsa-miR-181b	CLIP-seq
MIRT862974	hsa-miR-181c	CLIP-seq
MIRT862975	hsa-miR-181d	CLIP-seq
MIRT862976	hsa-miR-188-3p	CLIP-seq
MIRT862977	hsa-miR-1908	CLIP-seq
MIRT862978	hsa-miR-1909	CLIP-seq
MIRT862979	hsa-miR-195	CLIP-seq
MIRT862980	hsa-miR-1972	CLIP-seq
MIRT862981	hsa-miR-199a-3p	CLIP-seq
MIRT862982	hsa-miR-199b-3p	CLIP-seq
MIRT862983	hsa-miR-2276	CLIP-seq
MIRT862984	hsa-miR-2392	CLIP-seq
MIRT862985	hsa-miR-26a	CLIP-seq
MIRT862986	hsa-miR-26b	CLIP-seq
MIRT862987	hsa-miR-27a	CLIP-seq
MIRT862988	hsa-miR-27b	CLIP-seq
MIRT862989	hsa-miR-3129-5p	CLIP-seq
MIRT862990	hsa-miR-3132	CLIP-seq
MIRT862991	hsa-miR-3144-5p	CLIP-seq
MIRT862992	hsa-miR-3148	CLIP-seq
MIRT862993	hsa-miR-3156-3p	CLIP-seq
MIRT862994	hsa-miR-3179	CLIP-seq
MIRT862995	hsa-miR-3180	CLIP-seq
MIRT862996	hsa-miR-3180-3p	CLIP-seq
MIRT862997	hsa-miR-3189-5p	CLIP-seq
MIRT862998	hsa-miR-3196	CLIP-seq
MIRT862999	hsa-miR-3199	CLIP-seq
MIRT863000	hsa-miR-338-3p	CLIP-seq
MIRT863001	hsa-miR-342-5p	CLIP-seq
MIRT863002	hsa-miR-346	CLIP-seq
MIRT863003	hsa-miR-3613-5p	CLIP-seq
MIRT863004	hsa-miR-3618	CLIP-seq
MIRT863005	hsa-miR-362-5p	CLIP-seq
MIRT863006	hsa-miR-3649	CLIP-seq
MIRT863007	hsa-miR-3657	CLIP-seq
MIRT863008	hsa-miR-3661	CLIP-seq
MIRT863009	hsa-miR-3940-5p	CLIP-seq
MIRT863010	hsa-miR-424	CLIP-seq
MIRT863011	hsa-miR-4262	CLIP-seq
MIRT863012	hsa-miR-4288	CLIP-seq
MIRT863013	hsa-miR-4300	CLIP-seq
MIRT863014	hsa-miR-4301	CLIP-seq
MIRT863015	hsa-miR-4311	CLIP-seq
MIRT863016	hsa-miR-4316	CLIP-seq
MIRT863017	hsa-miR-4419a	CLIP-seq
MIRT863018	hsa-miR-4435	CLIP-seq
MIRT863019	hsa-miR-4443	CLIP-seq
MIRT863020	hsa-miR-4446-3p	CLIP-seq
MIRT863021	hsa-miR-4447	CLIP-seq
MIRT863022	hsa-miR-4451	CLIP-seq
MIRT863023	hsa-miR-4465	CLIP-seq
MIRT863024	hsa-miR-4472	CLIP-seq
MIRT863025	hsa-miR-4475	CLIP-seq
MIRT863026	hsa-miR-4488	CLIP-seq
MIRT863027	hsa-miR-4492	CLIP-seq
MIRT863028	hsa-miR-4498	CLIP-seq
MIRT863029	hsa-miR-4507	CLIP-seq
MIRT863030	hsa-miR-4510	CLIP-seq
MIRT863031	hsa-miR-4514	CLIP-seq
MIRT863032	hsa-miR-4515	CLIP-seq
MIRT863033	hsa-miR-4527	CLIP-seq
MIRT863034	hsa-miR-4530	CLIP-seq
MIRT863035	hsa-miR-4532	CLIP-seq
MIRT863036	hsa-miR-4534	CLIP-seq
MIRT863037	hsa-miR-4633-3p	CLIP-seq
MIRT863038	hsa-miR-4639-5p	CLIP-seq
MIRT863039	hsa-miR-4650-5p	CLIP-seq
MIRT863040	hsa-miR-4651	CLIP-seq
MIRT863041	hsa-miR-4664-5p	CLIP-seq
MIRT863042	hsa-miR-4692	CLIP-seq
MIRT863043	hsa-miR-4697-5p	CLIP-seq
MIRT863044	hsa-miR-4708-3p	CLIP-seq
MIRT863045	hsa-miR-4711-3p	CLIP-seq
MIRT863046	hsa-miR-4724-3p	CLIP-seq
MIRT863047	hsa-miR-4726-3p	CLIP-seq
MIRT863048	hsa-miR-4732-5p	CLIP-seq
MIRT863049	hsa-miR-4734	CLIP-seq
MIRT863050	hsa-miR-4736	CLIP-seq
MIRT863051	hsa-miR-4755-3p	CLIP-seq
MIRT863052	hsa-miR-4802-5p	CLIP-seq
MIRT863053	hsa-miR-492	CLIP-seq
MIRT863054	hsa-miR-497	CLIP-seq
MIRT863055	hsa-miR-500b	CLIP-seq
MIRT863056	hsa-miR-510	CLIP-seq
MIRT863057	hsa-miR-512-5p	CLIP-seq
MIRT863058	hsa-miR-513a-5p	CLIP-seq
MIRT863059	hsa-miR-542-3p	CLIP-seq
MIRT863060	hsa-miR-548p	CLIP-seq
MIRT863061	hsa-miR-548t	CLIP-seq
MIRT863062	hsa-miR-566	CLIP-seq
MIRT863063	hsa-miR-595	CLIP-seq
MIRT863064	hsa-miR-608	CLIP-seq
MIRT863065	hsa-miR-609	CLIP-seq
MIRT863066	hsa-miR-624	CLIP-seq
MIRT863067	hsa-miR-631	CLIP-seq
MIRT863068	hsa-miR-632	CLIP-seq
MIRT863069	hsa-miR-652	CLIP-seq
MIRT863070	hsa-miR-663	CLIP-seq
MIRT863071	hsa-miR-762	CLIP-seq
MIRT863072	hsa-miR-9	CLIP-seq
MIRT863073	hsa-miR-920	CLIP-seq
MIRT863074	hsa-miR-922	CLIP-seq
MIRT863075	hsa-miR-939	CLIP-seq
MIRT1955926	hsa-miR-103a	CLIP-seq
MIRT1955927	hsa-miR-107	CLIP-seq
MIRT1955928	hsa-miR-1184	CLIP-seq
MIRT862959	hsa-miR-1205	CLIP-seq
MIRT862961	hsa-miR-1245b-3p	CLIP-seq
MIRT1955929	hsa-miR-1266	CLIP-seq
MIRT862964	hsa-miR-128	CLIP-seq
MIRT862965	hsa-miR-1283	CLIP-seq
MIRT1955930	hsa-miR-1470	CLIP-seq
MIRT862969	hsa-miR-15a	CLIP-seq
MIRT862970	hsa-miR-15b	CLIP-seq
MIRT862971	hsa-miR-16	CLIP-seq
MIRT862972	hsa-miR-181a	CLIP-seq
MIRT862973	hsa-miR-181b	CLIP-seq
MIRT862974	hsa-miR-181c	CLIP-seq
MIRT862975	hsa-miR-181d	CLIP-seq
MIRT862977	hsa-miR-1908	CLIP-seq
MIRT862978	hsa-miR-1909	CLIP-seq
MIRT862979	hsa-miR-195	CLIP-seq
MIRT862981	hsa-miR-199a-3p	CLIP-seq
MIRT862982	hsa-miR-199b-3p	CLIP-seq
MIRT862987	hsa-miR-27a	CLIP-seq
MIRT862988	hsa-miR-27b	CLIP-seq
MIRT1955931	hsa-miR-3127-5p	CLIP-seq
MIRT862989	hsa-miR-3129-5p	CLIP-seq
MIRT1955932	hsa-miR-3136-3p	CLIP-seq
MIRT862991	hsa-miR-3144-5p	CLIP-seq
MIRT862994	hsa-miR-3179	CLIP-seq
MIRT862995	hsa-miR-3180	CLIP-seq
MIRT862996	hsa-miR-3180-3p	CLIP-seq
MIRT1955933	hsa-miR-3191	CLIP-seq
MIRT862998	hsa-miR-3196	CLIP-seq
MIRT862999	hsa-miR-3199	CLIP-seq
MIRT863000	hsa-miR-338-3p	CLIP-seq
MIRT863001	hsa-miR-342-5p	CLIP-seq
MIRT1955934	hsa-miR-34a	CLIP-seq
MIRT1955935	hsa-miR-34c-5p	CLIP-seq
MIRT863003	hsa-miR-3613-5p	CLIP-seq
MIRT863004	hsa-miR-3618	CLIP-seq
MIRT863006	hsa-miR-3649	CLIP-seq
MIRT1955936	hsa-miR-3677-5p	CLIP-seq
MIRT1955937	hsa-miR-3689d	CLIP-seq
MIRT1955938	hsa-miR-3913-3p	CLIP-seq
MIRT1955939	hsa-miR-3918	CLIP-seq
MIRT1955940	hsa-miR-3922-5p	CLIP-seq
MIRT863009	hsa-miR-3940-5p	CLIP-seq
MIRT1955941	hsa-miR-3960	CLIP-seq
MIRT863010	hsa-miR-424	CLIP-seq
MIRT863011	hsa-miR-4262	CLIP-seq
MIRT863021	hsa-miR-4447	CLIP-seq
MIRT1955942	hsa-miR-4467	CLIP-seq
MIRT863024	hsa-miR-4472	CLIP-seq
MIRT1955943	hsa-miR-4481	CLIP-seq
MIRT863026	hsa-miR-4488	CLIP-seq
MIRT1955944	hsa-miR-449a	CLIP-seq
MIRT1955945	hsa-miR-449b	CLIP-seq
MIRT863029	hsa-miR-4507	CLIP-seq
MIRT863032	hsa-miR-4515	CLIP-seq
MIRT1955946	hsa-miR-4518	CLIP-seq
MIRT863034	hsa-miR-4530	CLIP-seq
MIRT863035	hsa-miR-4532	CLIP-seq
MIRT863040	hsa-miR-4651	CLIP-seq
MIRT1955947	hsa-miR-4652-5p	CLIP-seq
MIRT863041	hsa-miR-4664-5p	CLIP-seq
MIRT1955948	hsa-miR-4667-3p	CLIP-seq
MIRT1955949	hsa-miR-4691-3p	CLIP-seq
MIRT863043	hsa-miR-4697-5p	CLIP-seq
MIRT863047	hsa-miR-4726-3p	CLIP-seq
MIRT1955950	hsa-miR-4743	CLIP-seq
MIRT1955951	hsa-miR-4745-5p	CLIP-seq
MIRT1955952	hsa-miR-4758-5p	CLIP-seq
MIRT1955953	hsa-miR-491-5p	CLIP-seq
MIRT863053	hsa-miR-492	CLIP-seq
MIRT863054	hsa-miR-497	CLIP-seq
MIRT1955954	hsa-miR-574-3p	CLIP-seq
MIRT863064	hsa-miR-608	CLIP-seq
MIRT1955955	hsa-miR-618	CLIP-seq
MIRT863066	hsa-miR-624	CLIP-seq
MIRT1955956	hsa-miR-642a	CLIP-seq
MIRT863070	hsa-miR-663	CLIP-seq
MIRT1955957	hsa-miR-758	CLIP-seq
MIRT863074	hsa-miR-922	CLIP-seq
MIRT862959	hsa-miR-1205	CLIP-seq
MIRT862962	hsa-miR-1260	CLIP-seq
MIRT862963	hsa-miR-1260b	CLIP-seq
MIRT1955929	hsa-miR-1266	CLIP-seq
MIRT862964	hsa-miR-128	CLIP-seq
MIRT862965	hsa-miR-1283	CLIP-seq
MIRT862968	hsa-miR-1297	CLIP-seq
MIRT862969	hsa-miR-15a	CLIP-seq
MIRT862970	hsa-miR-15b	CLIP-seq
MIRT862971	hsa-miR-16	CLIP-seq
MIRT862972	hsa-miR-181a	CLIP-seq
MIRT862973	hsa-miR-181b	CLIP-seq
MIRT862974	hsa-miR-181c	CLIP-seq
MIRT862975	hsa-miR-181d	CLIP-seq
MIRT862976	hsa-miR-188-3p	CLIP-seq
MIRT862977	hsa-miR-1908	CLIP-seq
MIRT862978	hsa-miR-1909	CLIP-seq
MIRT862979	hsa-miR-195	CLIP-seq
MIRT862981	hsa-miR-199a-3p	CLIP-seq
MIRT862982	hsa-miR-199b-3p	CLIP-seq
MIRT862984	hsa-miR-2392	CLIP-seq
MIRT862985	hsa-miR-26a	CLIP-seq
MIRT862986	hsa-miR-26b	CLIP-seq
MIRT862987	hsa-miR-27a	CLIP-seq
MIRT862988	hsa-miR-27b	CLIP-seq
MIRT2193547	hsa-miR-296-5p	CLIP-seq
MIRT1955931	hsa-miR-3127-5p	CLIP-seq
MIRT862989	hsa-miR-3129-5p	CLIP-seq
MIRT862991	hsa-miR-3144-5p	CLIP-seq
MIRT2193548	hsa-miR-3150a-3p	CLIP-seq
MIRT862993	hsa-miR-3156-3p	CLIP-seq
MIRT2193549	hsa-miR-3175	CLIP-seq
MIRT862994	hsa-miR-3179	CLIP-seq
MIRT862995	hsa-miR-3180	CLIP-seq
MIRT862996	hsa-miR-3180-3p	CLIP-seq
MIRT1955933	hsa-miR-3191	CLIP-seq
MIRT862998	hsa-miR-3196	CLIP-seq
MIRT862999	hsa-miR-3199	CLIP-seq
MIRT863001	hsa-miR-342-5p	CLIP-seq
MIRT863003	hsa-miR-3613-5p	CLIP-seq
MIRT863004	hsa-miR-3618	CLIP-seq
MIRT863006	hsa-miR-3649	CLIP-seq
MIRT1955937	hsa-miR-3689d	CLIP-seq
MIRT1955939	hsa-miR-3918	CLIP-seq
MIRT863009	hsa-miR-3940-5p	CLIP-seq
MIRT863010	hsa-miR-424	CLIP-seq
MIRT863011	hsa-miR-4262	CLIP-seq
MIRT863014	hsa-miR-4301	CLIP-seq
MIRT863018	hsa-miR-4435	CLIP-seq
MIRT863021	hsa-miR-4447	CLIP-seq
MIRT863023	hsa-miR-4465	CLIP-seq
MIRT863024	hsa-miR-4472	CLIP-seq
MIRT863026	hsa-miR-4488	CLIP-seq
MIRT863029	hsa-miR-4507	CLIP-seq
MIRT863031	hsa-miR-4514	CLIP-seq
MIRT863032	hsa-miR-4515	CLIP-seq
MIRT1955946	hsa-miR-4518	CLIP-seq
MIRT863040	hsa-miR-4651	CLIP-seq
MIRT863041	hsa-miR-4664-5p	CLIP-seq
MIRT863042	hsa-miR-4692	CLIP-seq
MIRT863043	hsa-miR-4697-5p	CLIP-seq
MIRT2193550	hsa-miR-4716-3p	CLIP-seq
MIRT863046	hsa-miR-4724-3p	CLIP-seq
MIRT863051	hsa-miR-4755-3p	CLIP-seq
MIRT2193551	hsa-miR-4786-3p	CLIP-seq
MIRT1955953	hsa-miR-491-5p	CLIP-seq
MIRT863053	hsa-miR-492	CLIP-seq
MIRT863054	hsa-miR-497	CLIP-seq
MIRT2193552	hsa-miR-541	CLIP-seq
MIRT1955954	hsa-miR-574-3p	CLIP-seq
MIRT863063	hsa-miR-595	CLIP-seq
MIRT863064	hsa-miR-608	CLIP-seq
MIRT863066	hsa-miR-624	CLIP-seq
MIRT2193553	hsa-miR-654-5p	CLIP-seq
MIRT863070	hsa-miR-663	CLIP-seq
MIRT2193554	hsa-miR-744	CLIP-seq
MIRT863075	hsa-miR-939	CLIP-seq
MIRT862964	hsa-miR-128	CLIP-seq
MIRT862965	hsa-miR-1283	CLIP-seq
MIRT862966	hsa-miR-1294	CLIP-seq
MIRT862968	hsa-miR-1297	CLIP-seq
MIRT862972	hsa-miR-181a	CLIP-seq
MIRT862973	hsa-miR-181b	CLIP-seq
MIRT862974	hsa-miR-181c	CLIP-seq
MIRT862975	hsa-miR-181d	CLIP-seq
MIRT862981	hsa-miR-199a-3p	CLIP-seq
MIRT862982	hsa-miR-199b-3p	CLIP-seq
MIRT862985	hsa-miR-26a	CLIP-seq
MIRT862986	hsa-miR-26b	CLIP-seq
MIRT862987	hsa-miR-27a	CLIP-seq
MIRT862988	hsa-miR-27b	CLIP-seq
MIRT862989	hsa-miR-3129-5p	CLIP-seq
MIRT862999	hsa-miR-3199	CLIP-seq
MIRT863004	hsa-miR-3618	CLIP-seq
MIRT863011	hsa-miR-4262	CLIP-seq
MIRT863016	hsa-miR-4316	CLIP-seq
MIRT863023	hsa-miR-4465	CLIP-seq
MIRT863032	hsa-miR-4515	CLIP-seq
MIRT863063	hsa-miR-595	CLIP-seq
MIRT863066	hsa-miR-624	CLIP-seq
MIRT1955926	hsa-miR-103a	CLIP-seq
MIRT1955927	hsa-miR-107	CLIP-seq
MIRT862969	hsa-miR-15a	CLIP-seq
MIRT862970	hsa-miR-15b	CLIP-seq
MIRT862971	hsa-miR-16	CLIP-seq
MIRT862979	hsa-miR-195	CLIP-seq
MIRT2446169	hsa-miR-3117-5p	CLIP-seq
MIRT2446170	hsa-miR-3163	CLIP-seq
MIRT863010	hsa-miR-424	CLIP-seq
MIRT2446171	hsa-miR-4282	CLIP-seq
MIRT863054	hsa-miR-497	CLIP-seq
MIRT1955926	hsa-miR-103a	CLIP-seq
MIRT1955927	hsa-miR-107	CLIP-seq
MIRT862969	hsa-miR-15a	CLIP-seq
MIRT862970	hsa-miR-15b	CLIP-seq
MIRT862971	hsa-miR-16	CLIP-seq
MIRT862979	hsa-miR-195	CLIP-seq
MIRT2446169	hsa-miR-3117-5p	CLIP-seq
MIRT2446170	hsa-miR-3163	CLIP-seq
MIRT863010	hsa-miR-424	CLIP-seq
MIRT2446171	hsa-miR-4282	CLIP-seq
MIRT863054	hsa-miR-497	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
NFKB1	Unknown	20462455
RELA	Unknown	20462455
TP53	Unknown	20462455

Show/Hide all (48)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000976	Function	Transcription cis-regulatory region binding	ISS
GO:0003713	Function	Transcription coactivator activity	IDA	15471871
GO:0003713	Function	Transcription coactivator activity	ISS
GO:0005515	Function	Protein binding	IPI	16938873, 20111005, 21911467, 23455924, 24434208, 24498420, 26267537, 33412112, 33961781
GO:0005634	Component	Nucleus	IDA	15221992
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IDA	15221992
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	ISS
GO:0006325	Process	Chromatin organization	IEA
GO:0006338	Process	Chromatin remodeling	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	ISS
GO:0006915	Process	Apoptotic process	IDA	34480022
GO:0008013	Function	Beta-catenin binding	TAS	16344550
GO:0008168	Function	Methyltransferase activity	IEA
GO:0008276	Function	Protein methyltransferase activity	IDA
GO:0008276	Function	Protein methyltransferase activity	IEA
GO:0008276	Function	Protein methyltransferase activity	ISS
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0008469	Function	Histone arginine N-methyltransferase activity	IDA	23980157
GO:0016274	Function	Protein-arginine N-methyltransferase activity	IDA	18495660
GO:0016274	Function	Protein-arginine N-methyltransferase activity	IEA
GO:0016274	Function	Protein-arginine N-methyltransferase activity	ISS
GO:0016274	Function	Protein-arginine N-methyltransferase activity	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0032259	Process	Methylation	IEA
GO:0033146	Process	Regulation of intracellular estrogen receptor signaling pathway	ISS
GO:0035242	Function	Protein-arginine omega-N asymmetric methyltransferase activity	IEA
GO:0035242	Function	Protein-arginine omega-N asymmetric methyltransferase activity	ISS
GO:0035642	Function	Histone H3R17 methyltransferase activity	IDA	15471871
GO:0035642	Function	Histone H3R17 methyltransferase activity	ISS
GO:0042054	Function	Histone methyltransferase activity	IDA
GO:0043596	Component	Nuclear replication fork	IDA	33412112
GO:0045600	Process	Positive regulation of fat cell differentiation	ISS
GO:0045943	Process	Positive regulation of transcription by RNA polymerase I	IDA	15471871
GO:0051591	Process	Response to cAMP	IEA
GO:0070611	Function	Histone H3R2 methyltransferase activity	IBA
GO:0070611	Function	Histone H3R2 methyltransferase activity	IMP	17898714
GO:0070611	Function	Histone H3R2 methyltransferase activity	ISS
GO:0071932	Process	Replication fork reversal	IDA	33412112
GO:0140297	Function	DNA-binding transcription factor binding	IPI	15471871
GO:1904037	Process	Positive regulation of epithelial cell apoptotic process	IDA	34480022
GO:2000171	Process	Negative regulation of dendrite development	IEA

MIM	HGNC	e!Ensembl
603934	23393	ENSG00000142453

Q86X55

Protein name

Histone-arginine methyltransferase CARM1 (EC 2.1.1.319) (Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4)

Protein function

Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability (PubMed:12237300, PubMed:16497732, PubMed:

PDB

2Y1W , 2Y1X , 4IKP , 5DWQ , 5DX0 , 5DX1 , 5DX8 , 5DXA , 5DXJ , 5U4X , 6ARJ , 6ARV , 6D2L , 6DVR , 6IZQ , 6S70 , 6S71 , 6S74 , 6S77 , 6S79 , 6S7A , 6S7B , 6S7C , 7FAI , 7FAJ , 7U9I , 8G2H , 8G2I , 8SIG , 8SIH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF11531	CARM1	28 → 139	Coactivator-associated arginine methyltransferase 1 N terminal	Domain
PF06325	PrmA	173 → 286		Family

Tissue specificity

TISSUE SPECIFICITY: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia. {ECO:0000269|PubMed:15221992}.

Sequence

MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
TNTMHYGS

Sequence length

608

Interactions

View interactions

	KEGG		Reactome
	Endocrine resistance		RORA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Estrogen-dependent gene expression

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Neurodevelopmental disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (65)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Coronary Syndrome	Coronary Syndrome	BEFREE	24530761		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute Erythroblastic Leukemia	Erythroblastic Leukemia	BEFREE	30257864		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	30366907		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	18172323, 21282336, 23663560, 23887673, 24434208, 26030442, 28432361, 28537268, 31217904, 31657716, 31833203		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	21612300, 23585185, 23663560, 23915145, 26030442, 28432361, 28537268, 31657716, 31833203, 33782401, 34663249	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	35033016	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	29991055, 34522186	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	24211191		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	32004442	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29434212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	Pubtator	35383293	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	31461302		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	20462455, 21478268, 28345460		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	21478268, 28345460, 32140074, 37997821	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	30173329		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	30173329		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	30173329		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic Retinopathy	BEFREE	25072916		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic retinopathy	Pubtator	32870623	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	26224097		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	29434212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Frontotemporal dementia	Frontotemporal dementia	BEFREE	30366907		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatitis B	Hepatitis b	Pubtator	23915145	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	37477799	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia, Familial	Hypercholesterolemia	GWASDB_DG	22968135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	36215477, 37477799	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	29894694		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lip and Oral Cavity Carcinoma	Lip and Oral Cavity Carcinoma	BEFREE	31217904		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung diseases	Lung Diseases	BEFREE	28637674		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	18172323, 20462455, 21282336, 23663560, 23887673, 24434208, 26030442, 28432361, 28537268, 31217904, 31657716, 31833203		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	30232003, 31799198		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	24211191		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of mouth	Malignant neoplasm of mouth	BEFREE	31217904		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	23434684, 29434212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	27840030		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	16705743, 20462455, 24019458		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23663560, 24211191, 26224097, 28537268, 29269946, 29434212, 29719619, 31657716		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	23486015		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	29269946, 29719619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	37477799	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy Duchenne	Duchenne muscular dystrophy	Pubtator	33004909	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Duchenne	Duchenne Muscular Dystrophy	BEFREE	29681515		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	31627895		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	35757636	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20462455, 21282336, 23343772, 23663560, 23887673, 24211191, 29434212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Neural Tube Defect	BEFREE	20932315		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	24211191, 30861415		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	33004909	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligospermia	Oligospermia	BEFREE	29659998		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	33004909	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	28924379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	28924379	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	29434212		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	32004442, 32049041	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	27840030		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	27840030	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parathyroid Neoplasms	Parathyroid neoplasm	Pubtator	38509667	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	16705743, 20462455, 24019458		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Intraepithelial Neoplasia	Prostatic intraepithelial neoplasia	Pubtator	15221992	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16705743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	34516499	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	CTD_human_DG	23143594		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pustulosis of Palms and Soles	Palmoplantar Pustules	CTD_human_DG	23143594		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rhabdomyosarcoma	Rhabdomyosarcoma	BEFREE	20213728		★★★★★ ★☆☆☆☆ Found in Text Mining only
Spinal Muscular Atrophy	Spinal Muscular Atrophy	BEFREE	17998247, 23136128, 26656492		★★★★★ ★☆☆☆☆ Found in Text Mining only

CARM1 (coactivator associated arginine methyltransferase 1)