Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10425
Gene name	Ariadne RBR E3 ubiquitin protein ligase 2
Gene symbol	ARIH2
Synonyms (NCBI Gene)	ARI2TRIAD1
Chromosome	3
Chromosome location	3p21.31
Summary	The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encod

402

Show/Hide all (402)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005396	hsa-miR-19a-3p	qRT-PCR	19296935
MIRT003366	hsa-miR-221-3p	Reporter assay;Microarray	20018759
MIRT028030	hsa-miR-93-5p	Sequencing	20371350
MIRT043669	hsa-miR-342-3p	CLASH	23622248
MIRT035998	hsa-miR-1301-3p	CLASH	23622248
MIRT570737	hsa-miR-5195-5p	PAR-CLIP	20371350
MIRT570736	hsa-miR-6777-3p	PAR-CLIP	20371350
MIRT570735	hsa-miR-125a-5p	PAR-CLIP	20371350
MIRT570734	hsa-miR-125b-5p	PAR-CLIP	20371350
MIRT570733	hsa-miR-4319	PAR-CLIP	20371350
MIRT570732	hsa-miR-610	PAR-CLIP	20371350
MIRT481579	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT481578	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT481577	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT481576	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT481575	hsa-miR-940	PAR-CLIP	23592263
MIRT481574	hsa-miR-2682-5p	PAR-CLIP	23592263
MIRT481573	hsa-miR-34b-5p	PAR-CLIP	23592263
MIRT481572	hsa-miR-449c-5p	PAR-CLIP	23592263
MIRT481571	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT210190	hsa-miR-6134	PAR-CLIP	23592263
MIRT481570	hsa-miR-197-5p	PAR-CLIP	23592263
MIRT481569	hsa-miR-3132	PAR-CLIP	23592263
MIRT210191	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT210193	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT210192	hsa-miR-6806-5p	PAR-CLIP	23592263
MIRT481568	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT210188	hsa-miR-1229-5p	PAR-CLIP	23592263
MIRT210189	hsa-miR-1304-5p	PAR-CLIP	23592263
MIRT481567	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT481566	hsa-miR-8055	PAR-CLIP	23592263
MIRT570735	hsa-miR-125a-5p	PAR-CLIP	27292025
MIRT570735	hsa-miR-125a-5p	PAR-CLIP	27292025
MIRT570734	hsa-miR-125b-5p	PAR-CLIP	27292025
MIRT570734	hsa-miR-125b-5p	PAR-CLIP	27292025
MIRT570733	hsa-miR-4319	PAR-CLIP	27292025
MIRT570733	hsa-miR-4319	PAR-CLIP	27292025
MIRT570737	hsa-miR-5195-5p	PAR-CLIP	27292025
MIRT570737	hsa-miR-5195-5p	PAR-CLIP	27292025
MIRT570732	hsa-miR-610	PAR-CLIP	27292025
MIRT570732	hsa-miR-610	PAR-CLIP	27292025
MIRT570736	hsa-miR-6777-3p	PAR-CLIP	27292025
MIRT570736	hsa-miR-6777-3p	PAR-CLIP	27292025
MIRT570737	hsa-miR-5195-5p	PAR-CLIP	20371350
MIRT570736	hsa-miR-6777-3p	PAR-CLIP	20371350
MIRT570735	hsa-miR-125a-5p	PAR-CLIP	20371350
MIRT570734	hsa-miR-125b-5p	PAR-CLIP	20371350
MIRT570733	hsa-miR-4319	PAR-CLIP	20371350
MIRT570732	hsa-miR-610	PAR-CLIP	20371350
MIRT481579	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT481578	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT481577	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT481576	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT481575	hsa-miR-940	PAR-CLIP	23592263
MIRT481574	hsa-miR-2682-5p	PAR-CLIP	23592263
MIRT481573	hsa-miR-34b-5p	PAR-CLIP	23592263
MIRT481572	hsa-miR-449c-5p	PAR-CLIP	23592263
MIRT481571	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT210190	hsa-miR-6134	PAR-CLIP	23592263
MIRT481570	hsa-miR-197-5p	PAR-CLIP	23592263
MIRT481569	hsa-miR-3132	PAR-CLIP	23592263
MIRT210191	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT210193	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT210192	hsa-miR-6806-5p	PAR-CLIP	23592263
MIRT481568	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT210188	hsa-miR-1229-5p	PAR-CLIP	23592263
MIRT210189	hsa-miR-1304-5p	PAR-CLIP	23592263
MIRT481567	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT481566	hsa-miR-8055	PAR-CLIP	23592263
MIRT797242	hsa-miR-103a	CLIP-seq
MIRT797243	hsa-miR-107	CLIP-seq
MIRT797244	hsa-miR-1197	CLIP-seq
MIRT797245	hsa-miR-1207-3p	CLIP-seq
MIRT797246	hsa-miR-129-5p	CLIP-seq
MIRT797247	hsa-miR-1301	CLIP-seq
MIRT797248	hsa-miR-1304	CLIP-seq
MIRT797249	hsa-miR-1305	CLIP-seq
MIRT797250	hsa-miR-181a	CLIP-seq
MIRT797251	hsa-miR-181b	CLIP-seq
MIRT797252	hsa-miR-181c	CLIP-seq
MIRT797253	hsa-miR-181d	CLIP-seq
MIRT797254	hsa-miR-1915	CLIP-seq
MIRT797255	hsa-miR-204	CLIP-seq
MIRT797256	hsa-miR-211	CLIP-seq
MIRT797257	hsa-miR-2277-3p	CLIP-seq
MIRT797258	hsa-miR-2278	CLIP-seq
MIRT797259	hsa-miR-2467-3p	CLIP-seq
MIRT797260	hsa-miR-29a	CLIP-seq
MIRT797261	hsa-miR-29b	CLIP-seq
MIRT797262	hsa-miR-29c	CLIP-seq
MIRT797263	hsa-miR-3065-3p	CLIP-seq
MIRT797264	hsa-miR-3145-5p	CLIP-seq
MIRT797265	hsa-miR-3149	CLIP-seq
MIRT797266	hsa-miR-3152-5p	CLIP-seq
MIRT797267	hsa-miR-3613-3p	CLIP-seq
MIRT797268	hsa-miR-365	CLIP-seq
MIRT797269	hsa-miR-3660	CLIP-seq
MIRT797270	hsa-miR-3688-3p	CLIP-seq
MIRT797271	hsa-miR-3689a-3p	CLIP-seq
MIRT797272	hsa-miR-3689c	CLIP-seq
MIRT797273	hsa-miR-378	CLIP-seq
MIRT797274	hsa-miR-378b	CLIP-seq
MIRT797275	hsa-miR-378c	CLIP-seq
MIRT797276	hsa-miR-378d	CLIP-seq
MIRT797277	hsa-miR-378e	CLIP-seq
MIRT797278	hsa-miR-378f	CLIP-seq
MIRT797279	hsa-miR-378h	CLIP-seq
MIRT797280	hsa-miR-378i	CLIP-seq
MIRT797281	hsa-miR-3918	CLIP-seq
MIRT797282	hsa-miR-3925-3p	CLIP-seq
MIRT797283	hsa-miR-3978	CLIP-seq
MIRT797284	hsa-miR-422a	CLIP-seq
MIRT797285	hsa-miR-4262	CLIP-seq
MIRT797286	hsa-miR-4263	CLIP-seq
MIRT797287	hsa-miR-4436a	CLIP-seq
MIRT797288	hsa-miR-4455	CLIP-seq
MIRT797289	hsa-miR-4470	CLIP-seq
MIRT797290	hsa-miR-4526	CLIP-seq
MIRT797291	hsa-miR-4638-3p	CLIP-seq
MIRT797292	hsa-miR-4639-3p	CLIP-seq
MIRT797293	hsa-miR-4645-5p	CLIP-seq
MIRT797294	hsa-miR-4673	CLIP-seq
MIRT797295	hsa-miR-4685-5p	CLIP-seq
MIRT797296	hsa-miR-4690-5p	CLIP-seq
MIRT797297	hsa-miR-4691-3p	CLIP-seq
MIRT797298	hsa-miR-4707-5p	CLIP-seq
MIRT797299	hsa-miR-4733-3p	CLIP-seq
MIRT797300	hsa-miR-4742-5p	CLIP-seq
MIRT797301	hsa-miR-4755-5p	CLIP-seq
MIRT797302	hsa-miR-4774-3p	CLIP-seq
MIRT797303	hsa-miR-4780	CLIP-seq
MIRT797304	hsa-miR-5047	CLIP-seq
MIRT797305	hsa-miR-568	CLIP-seq
MIRT797306	hsa-miR-607	CLIP-seq
MIRT797307	hsa-miR-623	CLIP-seq
MIRT797308	hsa-miR-642a	CLIP-seq
MIRT797309	hsa-miR-766	CLIP-seq
MIRT797242	hsa-miR-103a	CLIP-seq
MIRT797243	hsa-miR-107	CLIP-seq
MIRT1935435	hsa-miR-1184	CLIP-seq
MIRT1935436	hsa-miR-199a-5p	CLIP-seq
MIRT1935437	hsa-miR-199b-5p	CLIP-seq
MIRT1935438	hsa-miR-21	CLIP-seq
MIRT1935439	hsa-miR-214	CLIP-seq
MIRT797264	hsa-miR-3145-5p	CLIP-seq
MIRT1935440	hsa-miR-3619-5p	CLIP-seq
MIRT797273	hsa-miR-378	CLIP-seq
MIRT797274	hsa-miR-378b	CLIP-seq
MIRT797275	hsa-miR-378c	CLIP-seq
MIRT797276	hsa-miR-378d	CLIP-seq
MIRT797277	hsa-miR-378e	CLIP-seq
MIRT797278	hsa-miR-378f	CLIP-seq
MIRT797279	hsa-miR-378h	CLIP-seq
MIRT797280	hsa-miR-378i	CLIP-seq
MIRT797284	hsa-miR-422a	CLIP-seq
MIRT1935441	hsa-miR-452	CLIP-seq
MIRT797291	hsa-miR-4638-3p	CLIP-seq
MIRT1935442	hsa-miR-4676-3p	CLIP-seq
MIRT1935443	hsa-miR-590-5p	CLIP-seq
MIRT1935444	hsa-miR-761	CLIP-seq
MIRT1935445	hsa-miR-943	CLIP-seq
MIRT797242	hsa-miR-103a	CLIP-seq
MIRT797243	hsa-miR-107	CLIP-seq
MIRT1935435	hsa-miR-1184	CLIP-seq
MIRT2175487	hsa-miR-1208	CLIP-seq
MIRT2175488	hsa-miR-128	CLIP-seq
MIRT797247	hsa-miR-1301	CLIP-seq
MIRT2175489	hsa-miR-1972	CLIP-seq
MIRT797255	hsa-miR-204	CLIP-seq
MIRT797256	hsa-miR-211	CLIP-seq
MIRT1935439	hsa-miR-214	CLIP-seq
MIRT2175490	hsa-miR-218	CLIP-seq
MIRT2175491	hsa-miR-25	CLIP-seq
MIRT2175492	hsa-miR-27a	CLIP-seq
MIRT2175493	hsa-miR-27b	CLIP-seq
MIRT797260	hsa-miR-29a	CLIP-seq
MIRT797261	hsa-miR-29b	CLIP-seq
MIRT797262	hsa-miR-29c	CLIP-seq
MIRT797263	hsa-miR-3065-3p	CLIP-seq
MIRT2175494	hsa-miR-3122	CLIP-seq
MIRT2175495	hsa-miR-32	CLIP-seq
MIRT2175496	hsa-miR-338-3p	CLIP-seq
MIRT1935440	hsa-miR-3619-5p	CLIP-seq
MIRT2175497	hsa-miR-363	CLIP-seq
MIRT2175498	hsa-miR-367	CLIP-seq
MIRT2175499	hsa-miR-3714	CLIP-seq
MIRT2175500	hsa-miR-3913-5p	CLIP-seq
MIRT2175501	hsa-miR-3917	CLIP-seq
MIRT797281	hsa-miR-3918	CLIP-seq
MIRT2175502	hsa-miR-4279	CLIP-seq
MIRT2175503	hsa-miR-4286	CLIP-seq
MIRT2175504	hsa-miR-4289	CLIP-seq
MIRT2175505	hsa-miR-4422	CLIP-seq
MIRT2175506	hsa-miR-4530	CLIP-seq
MIRT2175507	hsa-miR-4641	CLIP-seq
MIRT797295	hsa-miR-4685-5p	CLIP-seq
MIRT797297	hsa-miR-4691-3p	CLIP-seq
MIRT2175508	hsa-miR-4700-3p	CLIP-seq
MIRT797298	hsa-miR-4707-5p	CLIP-seq
MIRT2175509	hsa-miR-4731-3p	CLIP-seq
MIRT2175510	hsa-miR-4733-5p	CLIP-seq
MIRT797301	hsa-miR-4755-5p	CLIP-seq
MIRT797303	hsa-miR-4780	CLIP-seq
MIRT2175511	hsa-miR-4801	CLIP-seq
MIRT797304	hsa-miR-5047	CLIP-seq
MIRT2175512	hsa-miR-513a-5p	CLIP-seq
MIRT2175513	hsa-miR-548ag	CLIP-seq
MIRT2175514	hsa-miR-548ai	CLIP-seq
MIRT797307	hsa-miR-623	CLIP-seq
MIRT1935444	hsa-miR-761	CLIP-seq
MIRT797309	hsa-miR-766	CLIP-seq
MIRT2175515	hsa-miR-92a	CLIP-seq
MIRT2175516	hsa-miR-92b	CLIP-seq
MIRT2384463	hsa-miR-1302	CLIP-seq
MIRT2175494	hsa-miR-3122	CLIP-seq
MIRT2384464	hsa-miR-3199	CLIP-seq
MIRT2175500	hsa-miR-3913-5p	CLIP-seq
MIRT2384465	hsa-miR-4298	CLIP-seq
MIRT2384466	hsa-miR-4423-5p	CLIP-seq
MIRT797298	hsa-miR-4707-5p	CLIP-seq
MIRT2384467	hsa-miR-4715-3p	CLIP-seq
MIRT2175510	hsa-miR-4733-5p	CLIP-seq
MIRT2384468	hsa-miR-4778-3p	CLIP-seq
MIRT2175512	hsa-miR-513a-5p	CLIP-seq
MIRT2384469	hsa-miR-9	CLIP-seq
MIRT797242	hsa-miR-103a	CLIP-seq
MIRT797243	hsa-miR-107	CLIP-seq
MIRT797245	hsa-miR-1207-3p	CLIP-seq
MIRT2478729	hsa-miR-1228	CLIP-seq
MIRT2478730	hsa-miR-124	CLIP-seq
MIRT2384463	hsa-miR-1302	CLIP-seq
MIRT797248	hsa-miR-1304	CLIP-seq
MIRT2478731	hsa-miR-139-5p	CLIP-seq
MIRT797250	hsa-miR-181a	CLIP-seq
MIRT797251	hsa-miR-181b	CLIP-seq
MIRT797252	hsa-miR-181c	CLIP-seq
MIRT797253	hsa-miR-181d	CLIP-seq
MIRT797254	hsa-miR-1915	CLIP-seq
MIRT2175489	hsa-miR-1972	CLIP-seq
MIRT2175490	hsa-miR-218	CLIP-seq
MIRT797257	hsa-miR-2277-3p	CLIP-seq
MIRT797258	hsa-miR-2278	CLIP-seq
MIRT797259	hsa-miR-2467-3p	CLIP-seq
MIRT2175491	hsa-miR-25	CLIP-seq
MIRT2478732	hsa-miR-2682	CLIP-seq
MIRT2175494	hsa-miR-3122	CLIP-seq
MIRT2478733	hsa-miR-3162-3p	CLIP-seq
MIRT2478734	hsa-miR-3176	CLIP-seq
MIRT2384464	hsa-miR-3199	CLIP-seq
MIRT2175495	hsa-miR-32	CLIP-seq
MIRT2478735	hsa-miR-329	CLIP-seq
MIRT2478736	hsa-miR-335	CLIP-seq
MIRT2175496	hsa-miR-338-3p	CLIP-seq
MIRT2478737	hsa-miR-3612	CLIP-seq
MIRT2478738	hsa-miR-3616-3p	CLIP-seq
MIRT2478739	hsa-miR-362-3p	CLIP-seq
MIRT2175497	hsa-miR-363	CLIP-seq
MIRT2478740	hsa-miR-3663-3p	CLIP-seq
MIRT2175498	hsa-miR-367	CLIP-seq
MIRT797270	hsa-miR-3688-3p	CLIP-seq
MIRT2175499	hsa-miR-3714	CLIP-seq
MIRT2478741	hsa-miR-3910	CLIP-seq
MIRT2175500	hsa-miR-3913-5p	CLIP-seq
MIRT797281	hsa-miR-3918	CLIP-seq
MIRT2478742	hsa-miR-3922-3p	CLIP-seq
MIRT2478743	hsa-miR-3926	CLIP-seq
MIRT2478744	hsa-miR-3938	CLIP-seq
MIRT797283	hsa-miR-3978	CLIP-seq
MIRT2478745	hsa-miR-4252	CLIP-seq
MIRT797285	hsa-miR-4262	CLIP-seq
MIRT797286	hsa-miR-4263	CLIP-seq
MIRT2478746	hsa-miR-4267	CLIP-seq
MIRT2478747	hsa-miR-4283	CLIP-seq
MIRT2384465	hsa-miR-4298	CLIP-seq
MIRT2478748	hsa-miR-4303	CLIP-seq
MIRT2175505	hsa-miR-4422	CLIP-seq
MIRT2478749	hsa-miR-4428	CLIP-seq
MIRT2478750	hsa-miR-4438	CLIP-seq
MIRT2478751	hsa-miR-4459	CLIP-seq
MIRT2478752	hsa-miR-449c	CLIP-seq
MIRT2478753	hsa-miR-451b	CLIP-seq
MIRT2175506	hsa-miR-4530	CLIP-seq
MIRT797291	hsa-miR-4638-3p	CLIP-seq
MIRT2175507	hsa-miR-4641	CLIP-seq
MIRT797293	hsa-miR-4645-5p	CLIP-seq
MIRT2478754	hsa-miR-4672	CLIP-seq
MIRT797294	hsa-miR-4673	CLIP-seq
MIRT797295	hsa-miR-4685-5p	CLIP-seq
MIRT2478755	hsa-miR-4695-5p	CLIP-seq
MIRT2478756	hsa-miR-4696	CLIP-seq
MIRT2384467	hsa-miR-4715-3p	CLIP-seq
MIRT2478757	hsa-miR-4716-3p	CLIP-seq
MIRT2478758	hsa-miR-4721	CLIP-seq
MIRT2478759	hsa-miR-4722-5p	CLIP-seq
MIRT2478760	hsa-miR-4725-5p	CLIP-seq
MIRT2478761	hsa-miR-4727-5p	CLIP-seq
MIRT797300	hsa-miR-4742-5p	CLIP-seq
MIRT2478762	hsa-miR-4769-3p	CLIP-seq
MIRT2478763	hsa-miR-4776-3p	CLIP-seq
MIRT2384468	hsa-miR-4778-3p	CLIP-seq
MIRT2478764	hsa-miR-4779	CLIP-seq
MIRT2478765	hsa-miR-504	CLIP-seq
MIRT2478766	hsa-miR-506	CLIP-seq
MIRT2478767	hsa-miR-5095	CLIP-seq
MIRT2175513	hsa-miR-548ag	CLIP-seq
MIRT2175514	hsa-miR-548ai	CLIP-seq
MIRT2478768	hsa-miR-548s	CLIP-seq
MIRT2478769	hsa-miR-548v	CLIP-seq
MIRT2478770	hsa-miR-622	CLIP-seq
MIRT2478771	hsa-miR-625	CLIP-seq
MIRT2478772	hsa-miR-650	CLIP-seq
MIRT797309	hsa-miR-766	CLIP-seq
MIRT2384469	hsa-miR-9	CLIP-seq
MIRT2175515	hsa-miR-92a	CLIP-seq
MIRT2175516	hsa-miR-92b	CLIP-seq
MIRT797242	hsa-miR-103a	CLIP-seq
MIRT797243	hsa-miR-107	CLIP-seq
MIRT797245	hsa-miR-1207-3p	CLIP-seq
MIRT2478729	hsa-miR-1228	CLIP-seq
MIRT2478730	hsa-miR-124	CLIP-seq
MIRT2384463	hsa-miR-1302	CLIP-seq
MIRT797248	hsa-miR-1304	CLIP-seq
MIRT2478731	hsa-miR-139-5p	CLIP-seq
MIRT797254	hsa-miR-1915	CLIP-seq
MIRT2175489	hsa-miR-1972	CLIP-seq
MIRT2175490	hsa-miR-218	CLIP-seq
MIRT797257	hsa-miR-2277-3p	CLIP-seq
MIRT797258	hsa-miR-2278	CLIP-seq
MIRT797259	hsa-miR-2467-3p	CLIP-seq
MIRT2175491	hsa-miR-25	CLIP-seq
MIRT2478732	hsa-miR-2682	CLIP-seq
MIRT2175494	hsa-miR-3122	CLIP-seq
MIRT2478733	hsa-miR-3162-3p	CLIP-seq
MIRT2478734	hsa-miR-3176	CLIP-seq
MIRT2675367	hsa-miR-3187-3p	CLIP-seq
MIRT2384464	hsa-miR-3199	CLIP-seq
MIRT2175495	hsa-miR-32	CLIP-seq
MIRT2478735	hsa-miR-329	CLIP-seq
MIRT2478736	hsa-miR-335	CLIP-seq
MIRT2478737	hsa-miR-3612	CLIP-seq
MIRT2478738	hsa-miR-3616-3p	CLIP-seq
MIRT2478739	hsa-miR-362-3p	CLIP-seq
MIRT2175497	hsa-miR-363	CLIP-seq
MIRT2478740	hsa-miR-3663-3p	CLIP-seq
MIRT2175498	hsa-miR-367	CLIP-seq
MIRT797270	hsa-miR-3688-3p	CLIP-seq
MIRT2175499	hsa-miR-3714	CLIP-seq
MIRT2478741	hsa-miR-3910	CLIP-seq
MIRT2175500	hsa-miR-3913-5p	CLIP-seq
MIRT797281	hsa-miR-3918	CLIP-seq
MIRT2478742	hsa-miR-3922-3p	CLIP-seq
MIRT2478743	hsa-miR-3926	CLIP-seq
MIRT2478744	hsa-miR-3938	CLIP-seq
MIRT797283	hsa-miR-3978	CLIP-seq
MIRT2478745	hsa-miR-4252	CLIP-seq
MIRT2478746	hsa-miR-4267	CLIP-seq
MIRT2478747	hsa-miR-4283	CLIP-seq
MIRT2384465	hsa-miR-4298	CLIP-seq
MIRT2478748	hsa-miR-4303	CLIP-seq
MIRT2175505	hsa-miR-4422	CLIP-seq
MIRT2478749	hsa-miR-4428	CLIP-seq
MIRT2675368	hsa-miR-4435	CLIP-seq
MIRT2478750	hsa-miR-4438	CLIP-seq
MIRT2478751	hsa-miR-4459	CLIP-seq
MIRT2675369	hsa-miR-4464	CLIP-seq
MIRT2478752	hsa-miR-449c	CLIP-seq
MIRT2478753	hsa-miR-451b	CLIP-seq
MIRT2175507	hsa-miR-4641	CLIP-seq
MIRT797293	hsa-miR-4645-5p	CLIP-seq
MIRT2478754	hsa-miR-4672	CLIP-seq
MIRT797294	hsa-miR-4673	CLIP-seq
MIRT797295	hsa-miR-4685-5p	CLIP-seq
MIRT2478755	hsa-miR-4695-5p	CLIP-seq
MIRT2478756	hsa-miR-4696	CLIP-seq
MIRT2675370	hsa-miR-4701-5p	CLIP-seq
MIRT2384467	hsa-miR-4715-3p	CLIP-seq
MIRT2478757	hsa-miR-4716-3p	CLIP-seq
MIRT2478758	hsa-miR-4721	CLIP-seq
MIRT2478759	hsa-miR-4722-5p	CLIP-seq
MIRT2478760	hsa-miR-4725-5p	CLIP-seq
MIRT2478761	hsa-miR-4727-5p	CLIP-seq
MIRT797300	hsa-miR-4742-5p	CLIP-seq
MIRT2675371	hsa-miR-4748	CLIP-seq
MIRT2478762	hsa-miR-4769-3p	CLIP-seq
MIRT2478763	hsa-miR-4776-3p	CLIP-seq
MIRT2384468	hsa-miR-4778-3p	CLIP-seq
MIRT2478764	hsa-miR-4779	CLIP-seq
MIRT2478765	hsa-miR-504	CLIP-seq
MIRT2478766	hsa-miR-506	CLIP-seq
MIRT2478767	hsa-miR-5095	CLIP-seq
MIRT2175513	hsa-miR-548ag	CLIP-seq
MIRT2175514	hsa-miR-548ai	CLIP-seq
MIRT2478768	hsa-miR-548s	CLIP-seq
MIRT2478769	hsa-miR-548v	CLIP-seq
MIRT2675372	hsa-miR-588	CLIP-seq
MIRT2478770	hsa-miR-622	CLIP-seq
MIRT2478771	hsa-miR-625	CLIP-seq
MIRT2478772	hsa-miR-650	CLIP-seq
MIRT797309	hsa-miR-766	CLIP-seq
MIRT2384469	hsa-miR-9	CLIP-seq
MIRT2175515	hsa-miR-92a	CLIP-seq
MIRT2175516	hsa-miR-92b	CLIP-seq

Show/Hide all (36)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IBA
GO:0000209	Process	Protein polyubiquitination	IDA	16118314, 19340006
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	16118314, 24076655
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0005515	Function	Protein binding	IPI	16118314, 16169070, 16189514, 19340006, 19549727, 22819825, 24076655, 25416956, 28514442, 30587576, 31515488, 32296183, 33961781
GO:0005634	Component	Nucleus	IDA	16118314
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	19340006
GO:0005737	Component	Cytoplasm	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	16118314
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	TAS	10422847
GO:0016567	Process	Protein ubiquitination	IDA	24076655
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0031466	Component	Cul5-RING ubiquitin ligase complex	IDA	24076655
GO:0031624	Function	Ubiquitin conjugating enzyme binding	IBA
GO:0031624	Function	Ubiquitin conjugating enzyme binding	IPI	24076655
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	22190037
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	31253590, 33268465
GO:0045087	Process	Innate immune response	IDA	22915799
GO:0046872	Function	Metal ion binding	IEA
GO:0048588	Process	Developmental cell growth	IDA	19340006
GO:0051607	Process	Defense response to virus	IDA	22915799
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	31253590, 33268465, 34518685, 38418882
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070534	Process	Protein K63-linked ubiquitination	IDA	19340006
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	16118314, 19340006
GO:0071425	Process	Hematopoietic stem cell proliferation	IDA	16118314, 19340006
GO:1903955	Process	Positive regulation of protein targeting to mitochondrion	HMP	24270810

MIM	HGNC	e!Ensembl
605615	690	ENSG00000177479

O95376

Protein name

E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (Triad1 protein)

Protein function

E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655, PubMed:33268465, PubMed:34518685, PubMed:384

PDB

7OD1 , 7ONI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01485	IBR	208 → 270	IBR domain, a half RING-finger domain	Domain
PF01485	IBR	279 → 340	IBR domain, a half RING-finger domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with higher expression in granulocytes. {ECO:0000269|PubMed:16118314}.

Sequence

MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ
FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA
RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG
VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ
EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC
NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE
ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC
RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE
QRRRTLLKDFHDT

Sequence length

493

Interactions

View interactions

	Reactome
			Antigen processing: Ubiquitination & Proteasome degradation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Autism spectrum disorder	Likely pathogenic	rs2471500241	RCV003494429	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Myoepithelial tumor	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Age related macular degeneration	Age-related macular degeneration	BEFREE	30681643		★★★★★ ★☆☆☆☆ Found in Text Mining only
Exudative age-related macular degeneration	Exudative Macular Degeneration	BEFREE	29190241		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glycogen storage disease type II	Glycogen Storage Disease	BEFREE	30681643		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	25671699	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	25671699	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	29459712		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	29459712		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	35732617	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2)