Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10376
Gene name	Tubulin alpha 1b
Gene symbol	TUBA1B
Synonyms (NCBI Gene)	K-ALPHA-1
Chromosome	12
Chromosome location	12q13.12

170

Show/Hide all (170)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016595	hsa-miR-193b-3p	Proteomics	21512034
MIRT052015	hsa-let-7b-5p	CLASH	23622248
MIRT052015	hsa-let-7b-5p	CLASH	23622248
MIRT051439	hsa-let-7e-5p	CLASH	23622248
MIRT049937	hsa-miR-30a-5p	CLASH	23622248
MIRT048292	hsa-miR-107	CLASH	23622248
MIRT048190	hsa-miR-196a-5p	CLASH	23622248
MIRT048190	hsa-miR-196a-5p	CLASH	23622248
MIRT047458	hsa-miR-10b-5p	CLASH	23622248
MIRT047209	hsa-miR-182-5p	CLASH	23622248
MIRT044555	hsa-miR-320a	CLASH	23622248
MIRT044555	hsa-miR-320a	CLASH	23622248
MIRT043044	hsa-miR-324-5p	CLASH	23622248
MIRT042042	hsa-miR-484	CLASH	23622248
MIRT042042	hsa-miR-484	CLASH	23622248
MIRT040370	hsa-miR-615-3p	CLASH	23622248
MIRT039463	hsa-miR-652-3p	CLASH	23622248
MIRT039463	hsa-miR-652-3p	CLASH	23622248
MIRT039413	hsa-miR-421	CLASH	23622248
MIRT038647	hsa-miR-140-3p	CLASH	23622248
MIRT038384	hsa-miR-296-3p	CLASH	23622248
MIRT037972	hsa-miR-505-5p	CLASH	23622248
MIRT037513	hsa-miR-744-5p	CLASH	23622248
MIRT037513	hsa-miR-744-5p	CLASH	23622248
MIRT037246	hsa-miR-877-5p	CLASH	23622248
MIRT037246	hsa-miR-877-5p	CLASH	23622248
MIRT036931	hsa-miR-877-3p	CLASH	23622248
MIRT036931	hsa-miR-877-3p	CLASH	23622248
MIRT036718	hsa-miR-760	CLASH	23622248
MIRT036718	hsa-miR-760	CLASH	23622248
MIRT036296	hsa-miR-1229-3p	CLASH	23622248
MIRT052893	hsa-miR-3934-5p	CLASH	23622248
MIRT504420	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT504419	hsa-miR-4643	PAR-CLIP	20371350
MIRT504418	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT504417	hsa-miR-1272	PAR-CLIP	20371350
MIRT504416	hsa-miR-1322	PAR-CLIP	20371350
MIRT504414	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT504413	hsa-miR-4534	PAR-CLIP	20371350
MIRT504412	hsa-miR-8082	PAR-CLIP	20371350
MIRT504411	hsa-miR-3134	PAR-CLIP	20371350
MIRT504410	hsa-miR-3148	PAR-CLIP	20371350
MIRT504409	hsa-miR-6124	PAR-CLIP	20371350
MIRT563810	hsa-miR-569	PAR-CLIP	20371350
MIRT504408	hsa-miR-466	PAR-CLIP	20371350
MIRT504407	hsa-miR-5095	PAR-CLIP	20371350
MIRT504406	hsa-miR-7151-3p	PAR-CLIP	20371350
MIRT563809	hsa-miR-2053	PAR-CLIP	20371350
MIRT504420	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT504419	hsa-miR-4643	PAR-CLIP	23446348
MIRT504418	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT504417	hsa-miR-1272	PAR-CLIP	23446348
MIRT504416	hsa-miR-1322	PAR-CLIP	23446348
MIRT504415	hsa-miR-3688-3p	PAR-CLIP	23446348
MIRT504414	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT504413	hsa-miR-4534	PAR-CLIP	23446348
MIRT504412	hsa-miR-8082	PAR-CLIP	23446348
MIRT504411	hsa-miR-3134	PAR-CLIP	23446348
MIRT504410	hsa-miR-3148	PAR-CLIP	23446348
MIRT504409	hsa-miR-6124	PAR-CLIP	23446348
MIRT504408	hsa-miR-466	PAR-CLIP	23446348
MIRT504407	hsa-miR-5095	PAR-CLIP	23446348
MIRT504406	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT504420	hsa-miR-4789-3p	PAR-CLIP	20371350
MIRT504419	hsa-miR-4643	PAR-CLIP	20371350
MIRT504418	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT504417	hsa-miR-1272	PAR-CLIP	20371350
MIRT504416	hsa-miR-1322	PAR-CLIP	20371350
MIRT504414	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT504413	hsa-miR-4534	PAR-CLIP	20371350
MIRT504412	hsa-miR-8082	PAR-CLIP	20371350
MIRT504411	hsa-miR-3134	PAR-CLIP	20371350
MIRT504410	hsa-miR-3148	PAR-CLIP	20371350
MIRT504409	hsa-miR-6124	PAR-CLIP	20371350
MIRT563810	hsa-miR-569	PAR-CLIP	20371350
MIRT504408	hsa-miR-466	PAR-CLIP	20371350
MIRT504407	hsa-miR-5095	PAR-CLIP	20371350
MIRT504406	hsa-miR-7151-3p	PAR-CLIP	20371350
MIRT563809	hsa-miR-2053	PAR-CLIP	20371350
MIRT504420	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT504419	hsa-miR-4643	PAR-CLIP	23446348
MIRT504418	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT504417	hsa-miR-1272	PAR-CLIP	23446348
MIRT504416	hsa-miR-1322	PAR-CLIP	23446348
MIRT504415	hsa-miR-3688-3p	PAR-CLIP	23446348
MIRT504414	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT504413	hsa-miR-4534	PAR-CLIP	23446348
MIRT504412	hsa-miR-8082	PAR-CLIP	23446348
MIRT504411	hsa-miR-3134	PAR-CLIP	23446348
MIRT504410	hsa-miR-3148	PAR-CLIP	23446348
MIRT504409	hsa-miR-6124	PAR-CLIP	23446348
MIRT504408	hsa-miR-466	PAR-CLIP	23446348
MIRT504407	hsa-miR-5095	PAR-CLIP	23446348
MIRT504406	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT1462977	hsa-miR-1205	CLIP-seq
MIRT1462978	hsa-miR-127-5p	CLIP-seq
MIRT1462979	hsa-miR-1909	CLIP-seq
MIRT1462980	hsa-miR-223	CLIP-seq
MIRT1462981	hsa-miR-3192	CLIP-seq
MIRT1462982	hsa-miR-320e	CLIP-seq
MIRT1462983	hsa-miR-3617	CLIP-seq
MIRT1462984	hsa-miR-3918	CLIP-seq
MIRT1462985	hsa-miR-3926	CLIP-seq
MIRT1462986	hsa-miR-4300	CLIP-seq
MIRT1462987	hsa-miR-4314	CLIP-seq
MIRT1462988	hsa-miR-4646-5p	CLIP-seq
MIRT1462989	hsa-miR-4697-3p	CLIP-seq
MIRT1462990	hsa-miR-4717-3p	CLIP-seq
MIRT1462991	hsa-miR-4802-3p	CLIP-seq
MIRT1462992	hsa-miR-552	CLIP-seq
MIRT1462993	hsa-miR-570	CLIP-seq
MIRT1462994	hsa-miR-641	CLIP-seq
MIRT1462995	hsa-miR-920	CLIP-seq
MIRT1462996	hsa-miR-935	CLIP-seq
MIRT1462977	hsa-miR-1205	CLIP-seq
MIRT1557232	hsa-miR-1261	CLIP-seq
MIRT1462979	hsa-miR-1909	CLIP-seq
MIRT1462984	hsa-miR-3918	CLIP-seq
MIRT1462985	hsa-miR-3926	CLIP-seq
MIRT1462977	hsa-miR-1205	CLIP-seq
MIRT1557232	hsa-miR-1261	CLIP-seq
MIRT1462978	hsa-miR-127-5p	CLIP-seq
MIRT1462979	hsa-miR-1909	CLIP-seq
MIRT1462980	hsa-miR-223	CLIP-seq
MIRT1462981	hsa-miR-3192	CLIP-seq
MIRT1462982	hsa-miR-320e	CLIP-seq
MIRT1462983	hsa-miR-3617	CLIP-seq
MIRT1462984	hsa-miR-3918	CLIP-seq
MIRT1462985	hsa-miR-3926	CLIP-seq
MIRT1462986	hsa-miR-4300	CLIP-seq
MIRT1462987	hsa-miR-4314	CLIP-seq
MIRT1462988	hsa-miR-4646-5p	CLIP-seq
MIRT1462989	hsa-miR-4697-3p	CLIP-seq
MIRT1462990	hsa-miR-4717-3p	CLIP-seq
MIRT1462991	hsa-miR-4802-3p	CLIP-seq
MIRT1462992	hsa-miR-552	CLIP-seq
MIRT1462993	hsa-miR-570	CLIP-seq
MIRT1462994	hsa-miR-641	CLIP-seq
MIRT1462995	hsa-miR-920	CLIP-seq
MIRT1462996	hsa-miR-935	CLIP-seq
MIRT1462977	hsa-miR-1205	CLIP-seq
MIRT1557232	hsa-miR-1261	CLIP-seq
MIRT1462978	hsa-miR-127-5p	CLIP-seq
MIRT1462979	hsa-miR-1909	CLIP-seq
MIRT1462980	hsa-miR-223	CLIP-seq
MIRT1462981	hsa-miR-3192	CLIP-seq
MIRT1462982	hsa-miR-320e	CLIP-seq
MIRT1462983	hsa-miR-3617	CLIP-seq
MIRT1462984	hsa-miR-3918	CLIP-seq
MIRT1462985	hsa-miR-3926	CLIP-seq
MIRT1462986	hsa-miR-4300	CLIP-seq
MIRT1462987	hsa-miR-4314	CLIP-seq
MIRT1462988	hsa-miR-4646-5p	CLIP-seq
MIRT1462989	hsa-miR-4697-3p	CLIP-seq
MIRT1462990	hsa-miR-4717-3p	CLIP-seq
MIRT1462991	hsa-miR-4802-3p	CLIP-seq
MIRT1462992	hsa-miR-552	CLIP-seq
MIRT1462993	hsa-miR-570	CLIP-seq
MIRT1462994	hsa-miR-641	CLIP-seq
MIRT1462995	hsa-miR-920	CLIP-seq
MIRT1462996	hsa-miR-935	CLIP-seq
MIRT1462978	hsa-miR-127-5p	CLIP-seq
MIRT1462980	hsa-miR-223	CLIP-seq
MIRT1462982	hsa-miR-320e	CLIP-seq
MIRT1462989	hsa-miR-4697-3p	CLIP-seq
MIRT1462990	hsa-miR-4717-3p	CLIP-seq
MIRT1462991	hsa-miR-4802-3p	CLIP-seq
MIRT1462992	hsa-miR-552	CLIP-seq
MIRT1462993	hsa-miR-570	CLIP-seq
MIRT1462996	hsa-miR-935	CLIP-seq

Show/Hide all (2)

Transcription factor	Regulation	Reference
PPARA	Unknown	23029400
RORA	Unknown	23029400

Show/Hide all (33)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000226	Process	Microtubule cytoskeleton organization	IBA
GO:0000226	Process	Microtubule cytoskeleton organization	IDA	34996871
GO:0000278	Process	Mitotic cell cycle	IBA
GO:0003725	Function	Double-stranded RNA binding	IDA	21266579
GO:0003924	Function	GTPase activity	IDA	34996871
GO:0005198	Function	Structural molecule activity	TAS	12090300
GO:0005200	Function	Structural constituent of cytoskeleton	IBA
GO:0005200	Function	Structural constituent of cytoskeleton	IDA	34996871
GO:0005200	Function	Structural constituent of cytoskeleton	IEA
GO:0005515	Function	Protein binding	IPI	11698390, 18457437, 24021646, 25416956, 32814053, 35271311
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IDA	34996871
GO:0005525	Function	GTP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IBA
GO:0005874	Component	Microtubule	IDA	21525035
GO:0005874	Component	Microtubule	IEA
GO:0005874	Component	Microtubule	TAS	12090300
GO:0005881	Component	Cytoplasmic microtubule	IEA
GO:0005929	Component	Cilium	IDA
GO:0007017	Process	Microtubule-based process	IEA
GO:0007017	Process	Microtubule-based process	TAS	12090300
GO:0015630	Component	Microtubule cytoskeleton	IDA	34996871
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0015630	Component	Microtubule cytoskeleton	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030705	Process	Cytoskeleton-dependent intracellular transport	TAS	12090300
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	21753002
GO:0051301	Process	Cell division	TAS	12090300
GO:0071353	Process	Cellular response to interleukin-4	IEA

MIM	HGNC	e!Ensembl
602530	18809	ENSG00000123416

P68363

Protein name

Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]

Protein function

Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed:38305685, PubMed:34996871, PubMed:38609661). Microtubules grow by the addition of GTP-tubulin dimers to the microtubul

PDB

2E4H , 5IJ0 , 5IJ9 , 5N5N , 6E7B , 6E7C , 6I2I , 6J4V , 6J8O , 6QUS , 6QUY , 6QVE , 6QVJ , 6S8L , 7LXB , 7M18 , 7M20 , 7PJF , 7SJ7 , 7SJ8 , 7SJ9 , 7SJA , 7Z6S , 7ZCW , 8T42 , 8U3Z , 8V2J , 8VA2 , 8VRJ , 8VRK , 8VT7 , 9BP6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00091	Tubulin	3 → 214	Tubulin/FtsZ family, GTPase domain	Domain
PF03953	Tubulin_C	263 → 393	Tubulin C-terminal domain	Domain

Sequence

MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY

Sequence length

451

Interactions

View interactions

	KEGG		Reactome
	Phagosome Apoptosis Tight junction Gap junction Motor proteins Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection		Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin HCMV Early Events Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Congenital fibrosis of extraocular muscles	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL FIBROSIS OF THE EXTRAOCULAR MUSCLES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROMUSCULAR DISEASES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOPOROSIS	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TUBA1B-associated neurodevelopmental disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (116)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Agyria	Agyria	BEFREE	20376468		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ameloblastoma	Ameloblastoma	Pubtator	34508164	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	30654731		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia Iron Deficiency	Iron deficiency anemia	Pubtator	29499633	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthenozoospermia	Asthenozoospermia	Pubtator	24268707	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	30233858		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia telangiectasia	Pubtator	31819434	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atypical Ductal Breast Hyperplasia	Breast Hyperplasia	BEFREE	19215229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Stem Neoplasms	Brain stem neoplasms	Pubtator	26130693	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	27228351, 28415012		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19215229, 19406749, 22200869, 25503560, 27228351, 37174666, 39232806	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	BEFREE	10866684		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	16101133	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ductal	Ductal carcinoma	Pubtator	19215229	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	30981109, 32685988, 37056756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Intraductal Noninfiltrating	Intraductal noninfiltrating carcinoma	Pubtator	19215229	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	10930805, 22904633, 30525585		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	29146868		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Hypertrophic	Hypertrophic cardiomyopathy	Pubtator	31323898	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Restrictive	Restrictive cardiomyopathy	Pubtator	36174041	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cataract	Cataract	Pubtator	32985730	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebrovascular accident	Stroke	BEFREE	30999900		★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	29716651		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	29716651		★★★★★ ★☆☆☆☆ Found in Text Mining only
Charcot-Marie-Tooth Disease	Charcot-Marie-Tooth Disease	BEFREE	27957719, 29415205		★★★★★ ★☆☆☆☆ Found in Text Mining only
Charcot-Marie-Tooth disease, Type 2D	Charcot-Marie-Tooth disease	BEFREE	29520015		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	BEFREE	28586053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cockayne Syndrome, Type II	Cockayne Syndrome	BEFREE	30158153		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	29320166		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	29027377	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	14973067, 28184026		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital anomaly of brain	Brain malformation	BEFREE	30016746, 31574570		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital diaphragmatic hernia	Congenital diaphragmatic hernia	BEFREE	30260286		★★★★★ ★☆☆☆☆ Found in Text Mining only
congenital fibrosis of the extraocular muscles	Congenital fibrosis of extraocular muscles	Pubtator	33649541	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CRANIOSYNOSTOSIS, TYPE 2	Craniosynostosis	BEFREE	30158153		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysautonomia, Familial	Dysautonomia	BEFREE	21273291, 29332244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	8099336		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	28067280		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver Alcoholic	Fatty liver, alcoholic	Pubtator	32685988	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Finnish congenital nephrotic syndrome	Finnish Congenital Nephrotic Syndrome	BEFREE	30193978		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	16257120	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	30261233, 30864703		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	30261233, 30864703		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulosclerosis Focal Segmental	Focal segmental glomerulosclerosis	Pubtator	33800671	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	19215229	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary hemochromatosis	Hereditary Hemochromatosis	BEFREE	29363254		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertrophic Cardiomyopathy	Hypertrophic cardiomyopathy	BEFREE	31323898		★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	30481203		★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	29320166, 29613911		★★★★★ ★☆☆☆☆ Found in Text Mining only
INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE AND FRONTOTEMPORAL DEMENTIA	Inclusion Body Myopathy With Paget Disease And Frontotemporal Dementia	BEFREE	30654731		★★★★★ ★☆☆☆☆ Found in Text Mining only
Iron deficiency anemia	Iron deficiency anemia	BEFREE	29499633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lissencephaly	Lissencephaly	BEFREE	17218254, 20376468		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lissencephaly	Lissencephaly	Pubtator	19896110, 26130693, 27431206	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	20502916, 23625295, 30981109		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	22904633	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	30176291		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Nephritis	Lupus Nephritis	BEFREE	28245046		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin	Non-Hodgkin lymphoma	BEFREE	24898903		★★★★★ ★☆☆☆☆ Found in Text Mining only
Macular dystrophy, corneal type 1	Macular corneal dystrophy	BEFREE	26739025		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malformations of Cortical Development	Cortical development malformation	Pubtator	26130693, 33649541	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malformations of Cortical Development, Group II	Malformation of cortical development	BEFREE	17218254		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of brain	Brain Neoplasms	BEFREE	29146868		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	24903226, 27228351, 28415012		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	10930805, 22904633, 30525585		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	27447976		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	16211407, 31578588		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27447976, 28456097, 29431641, 30168823, 31324789, 31612000		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	29716651		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	14973067, 28184026		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	12054644		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	22902175, 30176291		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	22570344		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	37085137	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood Disorder	BEFREE	29463911		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multicystic Dysplastic Kidney	Multicystic dysplastic kidney	Pubtator	33800671	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy Duchenne	Duchenne muscular dystrophy	Pubtator	31991054	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Nasal polyp	Pubtator	33982786	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	29747653	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	16891455, 23615402, 23625295, 28298077, 30176291, 30176876		★★★★★ ★☆☆☆☆ Found in Text Mining only
nervous system disorder	Nervous System Disorder	BEFREE	29320166		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	34638726	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	21377170		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuropsychiatric Systemic Lupus Erythematosus	Neuropsychiatric Systemic Lupus Erythematosus	BEFREE	20884345		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	20047843, 29641465, 29807114, 30429459		★★★★★ ★☆☆☆☆ Found in Text Mining only
Noninfiltrating Intraductal Carcinoma	Ductal carcinoma	BEFREE	19215229		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteitis Deformans	Paget disease	BEFREE	30654731		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteogenesis Imperfecta	Osteogenesis imperfecta	Pubtator	37566108	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	CTD_human_DG	18924182		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Osteoporosis, Age-Related	Osteoporosis	CTD_human_DG	18924182		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis, Postmenopausal	Osteoporosis	BEFREE	26676054		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis, Senile	Osteoporosis	CTD_human_DG	18924182		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	30936265, 31265888		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	30936265	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	19010849, 33475085	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	27447976		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	27447976	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	37348876	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pelvic Organ Prolapse	Pelvic organ prolapse	Pubtator	25923074	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pena Shokeir syndrome type 1	Pena-shokeir syndrome	Pubtator	33168876	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Diseases	Polycystic kidney disease	BEFREE	29366679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Polymicrogyria	Polymicrogyria	Pubtator	19896110, 22948023, 26130693	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polymicrogyria	Polymicrogyria	BEFREE	22948023		★★★★★ ★☆☆☆☆ Found in Text Mining only
Post-Traumatic Osteoporosis	Osteoporosis	CTD_human_DG	18924182		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	16211407, 31578588		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	18957327	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	34434188	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rett Syndrome	Rett Syndrome	BEFREE	25209898, 29730163		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rett Syndrome	Rett syndrome	Pubtator	29730163	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rhabdomyosarcoma	Rhabdomyosarcoma	BEFREE	17504194		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	30735241		★★★★★ ★☆☆☆☆ Found in Text Mining only
Thrombocytosis	Thrombocytosis	BEFREE	29499633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Thrombocytosis	Thrombocytosis	Pubtator	29499633	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Trichohepatoenteric Syndrome	Trichohepatoenteric Syndrome	BEFREE	16470743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	29027377		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	29716651	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Wilms Tumor	Wilms tumor	Pubtator	32908931	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TUBA1B (tubulin alpha 1b)