RTN3 (reticulon 3)

Gene

• Entrez ID: 10313
• Gene name: Reticulon 3
• Gene symbol: RTN3
• Synonyms (NCBI Gene): ASYIP, HAP, NSPL2, NSPLII, RTN3-A1
• Chromosome: 11
• Chromosome location: 11q13.1
• Summary: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the producti

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020529	hsa-miR-155-5p	Proteomics	18668040
MIRT050976	hsa-miR-17-5p	CLASH	23622248
MIRT048346	hsa-miR-106a-5p	CLASH	23622248
MIRT043942	hsa-miR-378a-3p	CLASH	23622248
MIRT041723	hsa-miR-484	CLASH	23622248
MIRT036707	hsa-miR-760	CLASH	23622248
MIRT699951	hsa-miR-4694-3p	HITS-CLIP	23313552
MIRT699950	hsa-miR-224-3p	HITS-CLIP	23313552
MIRT699949	hsa-miR-522-3p	HITS-CLIP	23313552
MIRT699948	hsa-miR-802	HITS-CLIP	23313552
MIRT699947	hsa-miR-367-5p	HITS-CLIP	23313552
MIRT699946	hsa-miR-4694-5p	HITS-CLIP	23313552
MIRT699945	hsa-miR-4684-3p	HITS-CLIP	23313552
MIRT699944	hsa-miR-33a-5p	HITS-CLIP	23313552
MIRT699943	hsa-miR-33b-5p	HITS-CLIP	23313552
MIRT699942	hsa-miR-4511	HITS-CLIP	23313552
MIRT560667	hsa-miR-6783-5p	PAR-CLIP	20371350
MIRT560668	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT560666	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT560665	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT560664	hsa-miR-4271	PAR-CLIP	20371350
MIRT560662	hsa-miR-4725-3p	PAR-CLIP	20371350
MIRT560663	hsa-miR-6780b-5p	PAR-CLIP	20371350
MIRT560661	hsa-miR-4443	PAR-CLIP	20371350
MIRT560660	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT439720	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT439720	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT699951	hsa-miR-4694-3p	HITS-CLIP	23313552
MIRT699950	hsa-miR-224-3p	HITS-CLIP	23313552
MIRT699949	hsa-miR-522-3p	HITS-CLIP	23313552
MIRT699948	hsa-miR-802	HITS-CLIP	23313552
MIRT699947	hsa-miR-367-5p	HITS-CLIP	23313552
MIRT699946	hsa-miR-4694-5p	HITS-CLIP	23313552
MIRT699945	hsa-miR-4684-3p	HITS-CLIP	23313552
MIRT699944	hsa-miR-33a-5p	HITS-CLIP	23313552
MIRT699943	hsa-miR-33b-5p	HITS-CLIP	23313552
MIRT699942	hsa-miR-4511	HITS-CLIP	23313552
MIRT560667	hsa-miR-6783-5p	PAR-CLIP	20371350
MIRT560668	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT560666	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT560665	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT560664	hsa-miR-4271	PAR-CLIP	20371350
MIRT560662	hsa-miR-4725-3p	PAR-CLIP	20371350
MIRT560663	hsa-miR-6780b-5p	PAR-CLIP	20371350
MIRT560661	hsa-miR-4443	PAR-CLIP	20371350
MIRT560660	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT1321976	hsa-miR-1178	CLIP-seq
MIRT1321977	hsa-miR-1197	CLIP-seq
MIRT1321978	hsa-miR-1207-5p	CLIP-seq
MIRT1321979	hsa-miR-124	CLIP-seq
MIRT1321980	hsa-miR-1273e	CLIP-seq
MIRT1321981	hsa-miR-1292	CLIP-seq
MIRT1321982	hsa-miR-129-5p	CLIP-seq
MIRT1321983	hsa-miR-1301	CLIP-seq
MIRT1321984	hsa-miR-1302	CLIP-seq
MIRT1321985	hsa-miR-1321	CLIP-seq
MIRT1321986	hsa-miR-140-3p	CLIP-seq
MIRT1321987	hsa-miR-148a	CLIP-seq
MIRT1321988	hsa-miR-148b	CLIP-seq
MIRT1321989	hsa-miR-152	CLIP-seq
MIRT1321990	hsa-miR-186	CLIP-seq
MIRT1321991	hsa-miR-1909	CLIP-seq
MIRT1321992	hsa-miR-1910	CLIP-seq
MIRT1321993	hsa-miR-1912	CLIP-seq
MIRT1321994	hsa-miR-203	CLIP-seq
MIRT1321995	hsa-miR-2113	CLIP-seq
MIRT1321996	hsa-miR-2116	CLIP-seq
MIRT1321997	hsa-miR-218	CLIP-seq
MIRT1321998	hsa-miR-22	CLIP-seq
MIRT1321999	hsa-miR-23a	CLIP-seq
MIRT1322000	hsa-miR-23b	CLIP-seq
MIRT1322001	hsa-miR-23c	CLIP-seq
MIRT1322002	hsa-miR-2467-3p	CLIP-seq
MIRT1322003	hsa-miR-3120-3p	CLIP-seq
MIRT1322004	hsa-miR-3122	CLIP-seq
MIRT1322005	hsa-miR-3124-3p	CLIP-seq
MIRT1322006	hsa-miR-3127-3p	CLIP-seq
MIRT1322007	hsa-miR-3133	CLIP-seq
MIRT1322008	hsa-miR-3151	CLIP-seq
MIRT1322009	hsa-miR-3159	CLIP-seq
MIRT1322010	hsa-miR-3168	CLIP-seq
MIRT1322011	hsa-miR-3175	CLIP-seq
MIRT1322012	hsa-miR-34c-3p	CLIP-seq
MIRT1322013	hsa-miR-361-5p	CLIP-seq
MIRT1322014	hsa-miR-3649	CLIP-seq
MIRT1322015	hsa-miR-3654	CLIP-seq
MIRT1322016	hsa-miR-3679-3p	CLIP-seq
MIRT1322017	hsa-miR-3714	CLIP-seq
MIRT1322018	hsa-miR-374c	CLIP-seq
MIRT1322019	hsa-miR-3910	CLIP-seq
MIRT1322020	hsa-miR-3913-5p	CLIP-seq
MIRT1322021	hsa-miR-3914	CLIP-seq
MIRT1322022	hsa-miR-4257	CLIP-seq
MIRT1322023	hsa-miR-4263	CLIP-seq
MIRT1322024	hsa-miR-4265	CLIP-seq
MIRT1322025	hsa-miR-4289	CLIP-seq
MIRT1322026	hsa-miR-4296	CLIP-seq
MIRT1322027	hsa-miR-4298	CLIP-seq
MIRT1322028	hsa-miR-4322	CLIP-seq
MIRT1322029	hsa-miR-4419a	CLIP-seq
MIRT1322030	hsa-miR-4421	CLIP-seq
MIRT1322031	hsa-miR-4426	CLIP-seq
MIRT1322032	hsa-miR-4447	CLIP-seq
MIRT1322033	hsa-miR-4472	CLIP-seq
MIRT1322034	hsa-miR-4477a	CLIP-seq
MIRT1322035	hsa-miR-4489	CLIP-seq
MIRT1322036	hsa-miR-450b-5p	CLIP-seq
MIRT1322037	hsa-miR-4510	CLIP-seq
MIRT1322038	hsa-miR-4519	CLIP-seq
MIRT1322039	hsa-miR-4520a-3p	CLIP-seq
MIRT1322040	hsa-miR-4534	CLIP-seq
MIRT1322041	hsa-miR-455-3p	CLIP-seq
MIRT1322042	hsa-miR-4638-3p	CLIP-seq
MIRT1322043	hsa-miR-4647	CLIP-seq
MIRT1322044	hsa-miR-4660	CLIP-seq
MIRT1322045	hsa-miR-4662a-3p	CLIP-seq
MIRT1322046	hsa-miR-4662b	CLIP-seq
MIRT1322047	hsa-miR-4677-5p	CLIP-seq
MIRT1322048	hsa-miR-4684-5p	CLIP-seq
MIRT1322049	hsa-miR-4700-3p	CLIP-seq
MIRT1322050	hsa-miR-4729	CLIP-seq
MIRT1322051	hsa-miR-4739	CLIP-seq
MIRT1322052	hsa-miR-4756-5p	CLIP-seq
MIRT1322053	hsa-miR-4763-3p	CLIP-seq
MIRT1322054	hsa-miR-4768-5p	CLIP-seq
MIRT1322055	hsa-miR-4777-3p	CLIP-seq
MIRT1322056	hsa-miR-483-3p	CLIP-seq
MIRT1322057	hsa-miR-486-3p	CLIP-seq
MIRT1322058	hsa-miR-491-5p	CLIP-seq
MIRT1322059	hsa-miR-498	CLIP-seq
MIRT1322060	hsa-miR-5047	CLIP-seq
MIRT1322061	hsa-miR-506	CLIP-seq
MIRT1322062	hsa-miR-507	CLIP-seq
MIRT1322063	hsa-miR-5095	CLIP-seq
MIRT1322064	hsa-miR-513c	CLIP-seq
MIRT1322065	hsa-miR-514b-5p	CLIP-seq
MIRT1322066	hsa-miR-541	CLIP-seq
MIRT1322067	hsa-miR-548a-3p	CLIP-seq
MIRT1322068	hsa-miR-548e	CLIP-seq
MIRT1322069	hsa-miR-548f	CLIP-seq
MIRT1322070	hsa-miR-557	CLIP-seq
MIRT1322071	hsa-miR-570	CLIP-seq
MIRT1322072	hsa-miR-579	CLIP-seq
MIRT1322073	hsa-miR-636	CLIP-seq
MIRT1322074	hsa-miR-654-5p	CLIP-seq
MIRT1322075	hsa-miR-655	CLIP-seq
MIRT1322076	hsa-miR-711	CLIP-seq
MIRT1322077	hsa-miR-767-3p	CLIP-seq
MIRT1322078	hsa-miR-873	CLIP-seq
MIRT1322079	hsa-miR-888	CLIP-seq
MIRT1322080	hsa-miR-935	CLIP-seq
MIRT1553202	hsa-miR-3616-3p	CLIP-seq
MIRT2095596	hsa-miR-1256	CLIP-seq
MIRT2095597	hsa-miR-1277	CLIP-seq
MIRT2095598	hsa-miR-154	CLIP-seq
MIRT1321994	hsa-miR-203	CLIP-seq
MIRT1321995	hsa-miR-2113	CLIP-seq
MIRT2095599	hsa-miR-2392	CLIP-seq
MIRT1322002	hsa-miR-2467-3p	CLIP-seq
MIRT1322005	hsa-miR-3124-3p	CLIP-seq
MIRT2095600	hsa-miR-329	CLIP-seq
MIRT1322012	hsa-miR-34c-3p	CLIP-seq
MIRT1322013	hsa-miR-361-5p	CLIP-seq
MIRT2095601	hsa-miR-362-3p	CLIP-seq
MIRT2095602	hsa-miR-3667-3p	CLIP-seq
MIRT2095603	hsa-miR-3673	CLIP-seq
MIRT2095604	hsa-miR-3677-5p	CLIP-seq
MIRT2095605	hsa-miR-3941	CLIP-seq
MIRT2095606	hsa-miR-4292	CLIP-seq
MIRT2095607	hsa-miR-4308	CLIP-seq
MIRT2095608	hsa-miR-432	CLIP-seq
MIRT1322029	hsa-miR-4419a	CLIP-seq
MIRT2095609	hsa-miR-4450	CLIP-seq
MIRT1322034	hsa-miR-4477a	CLIP-seq
MIRT1322037	hsa-miR-4510	CLIP-seq
MIRT2095610	hsa-miR-4667-5p	CLIP-seq
MIRT2095611	hsa-miR-4700-5p	CLIP-seq
MIRT2095612	hsa-miR-4730	CLIP-seq
MIRT1322054	hsa-miR-4768-5p	CLIP-seq
MIRT1322059	hsa-miR-498	CLIP-seq
MIRT1322071	hsa-miR-570	CLIP-seq
MIRT2095613	hsa-miR-603	CLIP-seq
MIRT2095614	hsa-miR-617	CLIP-seq
MIRT2095615	hsa-miR-670	CLIP-seq
MIRT1322078	hsa-miR-873	CLIP-seq
MIRT2320004	hsa-miR-1	CLIP-seq
MIRT2320005	hsa-miR-103a	CLIP-seq
MIRT2320006	hsa-miR-103b	CLIP-seq
MIRT2320007	hsa-miR-107	CLIP-seq
MIRT1321976	hsa-miR-1178	CLIP-seq
MIRT2320008	hsa-miR-1185	CLIP-seq
MIRT1321977	hsa-miR-1197	CLIP-seq
MIRT1321978	hsa-miR-1207-5p	CLIP-seq
MIRT2320009	hsa-miR-1243	CLIP-seq
MIRT2320010	hsa-miR-1245b-3p	CLIP-seq
MIRT2320011	hsa-miR-1255a	CLIP-seq
MIRT2320012	hsa-miR-1255b	CLIP-seq
MIRT2095596	hsa-miR-1256	CLIP-seq
MIRT2095597	hsa-miR-1277	CLIP-seq
MIRT1321982	hsa-miR-129-5p	CLIP-seq
MIRT1321983	hsa-miR-1301	CLIP-seq
MIRT1321984	hsa-miR-1302	CLIP-seq
MIRT2320013	hsa-miR-1323	CLIP-seq
MIRT2320014	hsa-miR-1343	CLIP-seq
MIRT1321987	hsa-miR-148a	CLIP-seq
MIRT1321988	hsa-miR-148b	CLIP-seq
MIRT1321989	hsa-miR-152	CLIP-seq
MIRT2320015	hsa-miR-15a	CLIP-seq
MIRT2320016	hsa-miR-15b	CLIP-seq
MIRT2320017	hsa-miR-16	CLIP-seq
MIRT1321990	hsa-miR-186	CLIP-seq
MIRT1321991	hsa-miR-1909	CLIP-seq
MIRT1321992	hsa-miR-1910	CLIP-seq
MIRT2320018	hsa-miR-195	CLIP-seq
MIRT2320019	hsa-miR-206	CLIP-seq
MIRT1321998	hsa-miR-22	CLIP-seq
MIRT2095599	hsa-miR-2392	CLIP-seq
MIRT1321999	hsa-miR-23a	CLIP-seq
MIRT1322000	hsa-miR-23b	CLIP-seq
MIRT1322001	hsa-miR-23c	CLIP-seq
MIRT1322002	hsa-miR-2467-3p	CLIP-seq
MIRT2320020	hsa-miR-298	CLIP-seq
MIRT2320021	hsa-miR-3117-5p	CLIP-seq
MIRT1322003	hsa-miR-3120-3p	CLIP-seq
MIRT2320022	hsa-miR-3121-5p	CLIP-seq
MIRT1322004	hsa-miR-3122	CLIP-seq
MIRT1322007	hsa-miR-3133	CLIP-seq
MIRT2320023	hsa-miR-3150b-3p	CLIP-seq
MIRT1322008	hsa-miR-3151	CLIP-seq
MIRT2320024	hsa-miR-3155	CLIP-seq
MIRT2320025	hsa-miR-3155b	CLIP-seq
MIRT2320026	hsa-miR-3156-3p	CLIP-seq
MIRT2320027	hsa-miR-3158-5p	CLIP-seq
MIRT1322011	hsa-miR-3175	CLIP-seq
MIRT2320028	hsa-miR-3192	CLIP-seq
MIRT2320029	hsa-miR-345	CLIP-seq
MIRT2320030	hsa-miR-34b	CLIP-seq
MIRT1322012	hsa-miR-34c-3p	CLIP-seq
MIRT2320031	hsa-miR-3605-5p	CLIP-seq
MIRT1322013	hsa-miR-361-5p	CLIP-seq
MIRT1553202	hsa-miR-3616-3p	CLIP-seq
MIRT2320032	hsa-miR-3619-3p	CLIP-seq
MIRT1322014	hsa-miR-3649	CLIP-seq
MIRT2320033	hsa-miR-3651	CLIP-seq
MIRT1322015	hsa-miR-3654	CLIP-seq
MIRT2095602	hsa-miR-3667-3p	CLIP-seq
MIRT2320034	hsa-miR-3671	CLIP-seq
MIRT2095603	hsa-miR-3673	CLIP-seq
MIRT2095604	hsa-miR-3677-5p	CLIP-seq
MIRT1322016	hsa-miR-3679-3p	CLIP-seq
MIRT2320035	hsa-miR-3679-5p	CLIP-seq
MIRT2320036	hsa-miR-3685	CLIP-seq
MIRT2320037	hsa-miR-3688-5p	CLIP-seq
MIRT2320038	hsa-miR-3689a-3p	CLIP-seq
MIRT2320039	hsa-miR-3689c	CLIP-seq
MIRT2320040	hsa-miR-370	CLIP-seq
MIRT1322020	hsa-miR-3913-5p	CLIP-seq
MIRT2320041	hsa-miR-424	CLIP-seq
MIRT2320042	hsa-miR-4264	CLIP-seq
MIRT1322024	hsa-miR-4265	CLIP-seq
MIRT1322025	hsa-miR-4289	CLIP-seq
MIRT1322026	hsa-miR-4296	CLIP-seq
MIRT1322027	hsa-miR-4298	CLIP-seq
MIRT2320043	hsa-miR-4301	CLIP-seq
MIRT2095608	hsa-miR-432	CLIP-seq
MIRT1322028	hsa-miR-4322	CLIP-seq
MIRT2320044	hsa-miR-4325	CLIP-seq
MIRT2320045	hsa-miR-4418	CLIP-seq
MIRT1322029	hsa-miR-4419a	CLIP-seq
MIRT2320046	hsa-miR-4420	CLIP-seq
MIRT1322030	hsa-miR-4421	CLIP-seq
MIRT2320047	hsa-miR-4432	CLIP-seq
MIRT2320048	hsa-miR-4434	CLIP-seq
MIRT2320049	hsa-miR-4436b-3p	CLIP-seq
MIRT2320050	hsa-miR-4436b-5p	CLIP-seq
MIRT1322032	hsa-miR-4447	CLIP-seq
MIRT2095609	hsa-miR-4450	CLIP-seq
MIRT2320051	hsa-miR-4453	CLIP-seq
MIRT2320052	hsa-miR-4469	CLIP-seq
MIRT1322033	hsa-miR-4472	CLIP-seq
MIRT1322036	hsa-miR-450b-5p	CLIP-seq
MIRT1322037	hsa-miR-4510	CLIP-seq
MIRT2320053	hsa-miR-4516	CLIP-seq
MIRT1322038	hsa-miR-4519	CLIP-seq
MIRT1322039	hsa-miR-4520a-3p	CLIP-seq
MIRT2320054	hsa-miR-4531	CLIP-seq
MIRT1322040	hsa-miR-4534	CLIP-seq
MIRT2320055	hsa-miR-4538	CLIP-seq
MIRT1322041	hsa-miR-455-3p	CLIP-seq
MIRT1322042	hsa-miR-4638-3p	CLIP-seq
MIRT1322044	hsa-miR-4660	CLIP-seq
MIRT1322045	hsa-miR-4662a-3p	CLIP-seq
MIRT2320056	hsa-miR-4689	CLIP-seq
MIRT2320057	hsa-miR-4705	CLIP-seq
MIRT2320058	hsa-miR-4728-5p	CLIP-seq
MIRT1322050	hsa-miR-4729	CLIP-seq
MIRT1322053	hsa-miR-4763-3p	CLIP-seq
MIRT2320059	hsa-miR-4763-5p	CLIP-seq
MIRT2320060	hsa-miR-4764-5p	CLIP-seq
MIRT1322054	hsa-miR-4768-5p	CLIP-seq
MIRT1322055	hsa-miR-4777-3p	CLIP-seq
MIRT2320061	hsa-miR-4784	CLIP-seq
MIRT2320062	hsa-miR-4797-3p	CLIP-seq
MIRT1322056	hsa-miR-483-3p	CLIP-seq
MIRT1322057	hsa-miR-486-3p	CLIP-seq
MIRT2320063	hsa-miR-487a	CLIP-seq
MIRT1322058	hsa-miR-491-5p	CLIP-seq
MIRT2320064	hsa-miR-493	CLIP-seq
MIRT2320065	hsa-miR-497	CLIP-seq
MIRT1322059	hsa-miR-498	CLIP-seq
MIRT2320066	hsa-miR-499-5p	CLIP-seq
MIRT1322060	hsa-miR-5047	CLIP-seq
MIRT1322062	hsa-miR-507	CLIP-seq
MIRT2320067	hsa-miR-509-3-5p	CLIP-seq
MIRT2320068	hsa-miR-509-5p	CLIP-seq
MIRT1322066	hsa-miR-541	CLIP-seq
MIRT1322067	hsa-miR-548a-3p	CLIP-seq
MIRT2320069	hsa-miR-548aa	CLIP-seq
MIRT2320070	hsa-miR-548ac	CLIP-seq
MIRT2320071	hsa-miR-548ae	CLIP-seq
MIRT2320072	hsa-miR-548aj	CLIP-seq
MIRT2320073	hsa-miR-548am	CLIP-seq
MIRT2320074	hsa-miR-548d-3p	CLIP-seq
MIRT1322068	hsa-miR-548e	CLIP-seq
MIRT1322069	hsa-miR-548f	CLIP-seq
MIRT2320075	hsa-miR-548o	CLIP-seq
MIRT2320076	hsa-miR-548x	CLIP-seq
MIRT2320077	hsa-miR-548z	CLIP-seq
MIRT1322070	hsa-miR-557	CLIP-seq
MIRT2320078	hsa-miR-587	CLIP-seq
MIRT2320079	hsa-miR-613	CLIP-seq
MIRT2095614	hsa-miR-617	CLIP-seq
MIRT2320080	hsa-miR-628-5p	CLIP-seq
MIRT1322074	hsa-miR-654-5p	CLIP-seq
MIRT1322077	hsa-miR-767-3p	CLIP-seq
MIRT1322078	hsa-miR-873	CLIP-seq
MIRT1322080	hsa-miR-935	CLIP-seq
MIRT2320005	hsa-miR-103a	CLIP-seq
MIRT2320007	hsa-miR-107	CLIP-seq
MIRT1321976	hsa-miR-1178	CLIP-seq
MIRT1321978	hsa-miR-1207-5p	CLIP-seq
MIRT2320010	hsa-miR-1245b-3p	CLIP-seq
MIRT2095596	hsa-miR-1256	CLIP-seq
MIRT2095597	hsa-miR-1277	CLIP-seq
MIRT1321981	hsa-miR-1292	CLIP-seq
MIRT1321985	hsa-miR-1321	CLIP-seq
MIRT1321987	hsa-miR-148a	CLIP-seq
MIRT1321988	hsa-miR-148b	CLIP-seq
MIRT1321989	hsa-miR-152	CLIP-seq
MIRT2095598	hsa-miR-154	CLIP-seq
MIRT2615888	hsa-miR-155	CLIP-seq
MIRT2615889	hsa-miR-1825	CLIP-seq
MIRT1321990	hsa-miR-186	CLIP-seq
MIRT1321991	hsa-miR-1909	CLIP-seq
MIRT1321992	hsa-miR-1910	CLIP-seq
MIRT2615890	hsa-miR-198	CLIP-seq
MIRT2615891	hsa-miR-199a-5p	CLIP-seq
MIRT2615892	hsa-miR-199b-5p	CLIP-seq
MIRT1321998	hsa-miR-22	CLIP-seq
MIRT1321999	hsa-miR-23a	CLIP-seq
MIRT1322000	hsa-miR-23b	CLIP-seq
MIRT1322001	hsa-miR-23c	CLIP-seq
MIRT1322003	hsa-miR-3120-3p	CLIP-seq
MIRT2615893	hsa-miR-3129-3p	CLIP-seq
MIRT1322007	hsa-miR-3133	CLIP-seq
MIRT2320023	hsa-miR-3150b-3p	CLIP-seq
MIRT2320026	hsa-miR-3156-3p	CLIP-seq
MIRT1322011	hsa-miR-3175	CLIP-seq
MIRT2095600	hsa-miR-329	CLIP-seq
MIRT2320029	hsa-miR-345	CLIP-seq
MIRT1322012	hsa-miR-34c-3p	CLIP-seq
MIRT1322013	hsa-miR-361-5p	CLIP-seq
MIRT2095601	hsa-miR-362-3p	CLIP-seq
MIRT2615894	hsa-miR-3665	CLIP-seq
MIRT2095603	hsa-miR-3673	CLIP-seq
MIRT2320040	hsa-miR-370	CLIP-seq
MIRT2615895	hsa-miR-371-5p	CLIP-seq
MIRT2615896	hsa-miR-371b-5p	CLIP-seq
MIRT2095605	hsa-miR-3941	CLIP-seq
MIRT2320042	hsa-miR-4264	CLIP-seq
MIRT2320043	hsa-miR-4301	CLIP-seq
MIRT2095608	hsa-miR-432	CLIP-seq
MIRT1322029	hsa-miR-4419a	CLIP-seq
MIRT2615897	hsa-miR-4464	CLIP-seq
MIRT2320052	hsa-miR-4469	CLIP-seq
MIRT1322034	hsa-miR-4477a	CLIP-seq
MIRT1322037	hsa-miR-4510	CLIP-seq
MIRT1322038	hsa-miR-4519	CLIP-seq
MIRT1322041	hsa-miR-455-3p	CLIP-seq
MIRT2615898	hsa-miR-4661-3p	CLIP-seq
MIRT1322048	hsa-miR-4684-5p	CLIP-seq
MIRT2320056	hsa-miR-4689	CLIP-seq
MIRT2615899	hsa-miR-4719	CLIP-seq
MIRT1322050	hsa-miR-4729	CLIP-seq
MIRT1322051	hsa-miR-4739	CLIP-seq
MIRT2615900	hsa-miR-4748	CLIP-seq
MIRT1322052	hsa-miR-4756-5p	CLIP-seq
MIRT1322053	hsa-miR-4763-3p	CLIP-seq
MIRT2320059	hsa-miR-4763-5p	CLIP-seq
MIRT1322054	hsa-miR-4768-5p	CLIP-seq
MIRT2320061	hsa-miR-4784	CLIP-seq
MIRT2320062	hsa-miR-4797-3p	CLIP-seq
MIRT2615901	hsa-miR-5096	CLIP-seq
MIRT1322064	hsa-miR-513c	CLIP-seq
MIRT1322065	hsa-miR-514b-5p	CLIP-seq
MIRT2615902	hsa-miR-526b	CLIP-seq
MIRT1322066	hsa-miR-541	CLIP-seq
MIRT2320071	hsa-miR-548ae	CLIP-seq
MIRT2320072	hsa-miR-548aj	CLIP-seq
MIRT2320073	hsa-miR-548am	CLIP-seq
MIRT2615903	hsa-miR-548k	CLIP-seq
MIRT2615904	hsa-miR-548n	CLIP-seq
MIRT2320076	hsa-miR-548x	CLIP-seq
MIRT2615905	hsa-miR-580	CLIP-seq
MIRT2320078	hsa-miR-587	CLIP-seq
MIRT2095613	hsa-miR-603	CLIP-seq
MIRT2320080	hsa-miR-628-5p	CLIP-seq
MIRT2615906	hsa-miR-642a	CLIP-seq
MIRT1322074	hsa-miR-654-5p	CLIP-seq
MIRT2615907	hsa-miR-657	CLIP-seq
MIRT1322077	hsa-miR-767-3p	CLIP-seq
MIRT1322078	hsa-miR-873	CLIP-seq
MIRT1322080	hsa-miR-935	CLIP-seq
MIRT2320005	hsa-miR-103a	CLIP-seq
MIRT2320007	hsa-miR-107	CLIP-seq
MIRT1321976	hsa-miR-1178	CLIP-seq
MIRT1321978	hsa-miR-1207-5p	CLIP-seq
MIRT2320010	hsa-miR-1245b-3p	CLIP-seq
MIRT2095596	hsa-miR-1256	CLIP-seq
MIRT2095597	hsa-miR-1277	CLIP-seq
MIRT1321981	hsa-miR-1292	CLIP-seq
MIRT1321985	hsa-miR-1321	CLIP-seq
MIRT1321987	hsa-miR-148a	CLIP-seq
MIRT1321988	hsa-miR-148b	CLIP-seq
MIRT1321989	hsa-miR-152	CLIP-seq
MIRT2095598	hsa-miR-154	CLIP-seq
MIRT2615888	hsa-miR-155	CLIP-seq
MIRT2615889	hsa-miR-1825	CLIP-seq
MIRT1321990	hsa-miR-186	CLIP-seq
MIRT1321991	hsa-miR-1909	CLIP-seq
MIRT1321992	hsa-miR-1910	CLIP-seq
MIRT2615890	hsa-miR-198	CLIP-seq
MIRT2615891	hsa-miR-199a-5p	CLIP-seq
MIRT2615892	hsa-miR-199b-5p	CLIP-seq
MIRT1321998	hsa-miR-22	CLIP-seq
MIRT1322003	hsa-miR-3120-3p	CLIP-seq
MIRT2615893	hsa-miR-3129-3p	CLIP-seq
MIRT1322007	hsa-miR-3133	CLIP-seq
MIRT2320023	hsa-miR-3150b-3p	CLIP-seq
MIRT2320026	hsa-miR-3156-3p	CLIP-seq
MIRT1322011	hsa-miR-3175	CLIP-seq
MIRT2095600	hsa-miR-329	CLIP-seq
MIRT2320029	hsa-miR-345	CLIP-seq
MIRT1322012	hsa-miR-34c-3p	CLIP-seq
MIRT1322013	hsa-miR-361-5p	CLIP-seq
MIRT2095601	hsa-miR-362-3p	CLIP-seq
MIRT2615894	hsa-miR-3665	CLIP-seq
MIRT2095603	hsa-miR-3673	CLIP-seq
MIRT2320040	hsa-miR-370	CLIP-seq
MIRT2615895	hsa-miR-371-5p	CLIP-seq
MIRT2615896	hsa-miR-371b-5p	CLIP-seq
MIRT2095605	hsa-miR-3941	CLIP-seq
MIRT2320042	hsa-miR-4264	CLIP-seq
MIRT2320043	hsa-miR-4301	CLIP-seq
MIRT2095608	hsa-miR-432	CLIP-seq
MIRT1322029	hsa-miR-4419a	CLIP-seq
MIRT2615897	hsa-miR-4464	CLIP-seq
MIRT2320052	hsa-miR-4469	CLIP-seq
MIRT1322034	hsa-miR-4477a	CLIP-seq
MIRT1322037	hsa-miR-4510	CLIP-seq
MIRT1322038	hsa-miR-4519	CLIP-seq
MIRT1322041	hsa-miR-455-3p	CLIP-seq
MIRT2615898	hsa-miR-4661-3p	CLIP-seq
MIRT1322048	hsa-miR-4684-5p	CLIP-seq
MIRT2320056	hsa-miR-4689	CLIP-seq
MIRT2615899	hsa-miR-4719	CLIP-seq
MIRT1322050	hsa-miR-4729	CLIP-seq
MIRT1322051	hsa-miR-4739	CLIP-seq
MIRT2615900	hsa-miR-4748	CLIP-seq
MIRT1322052	hsa-miR-4756-5p	CLIP-seq
MIRT1322053	hsa-miR-4763-3p	CLIP-seq
MIRT2320059	hsa-miR-4763-5p	CLIP-seq
MIRT1322054	hsa-miR-4768-5p	CLIP-seq
MIRT2320061	hsa-miR-4784	CLIP-seq
MIRT2320062	hsa-miR-4797-3p	CLIP-seq
MIRT1322064	hsa-miR-513c	CLIP-seq
MIRT1322065	hsa-miR-514b-5p	CLIP-seq
MIRT1322066	hsa-miR-541	CLIP-seq
MIRT2320071	hsa-miR-548ae	CLIP-seq
MIRT2320072	hsa-miR-548aj	CLIP-seq
MIRT2320073	hsa-miR-548am	CLIP-seq
MIRT2615903	hsa-miR-548k	CLIP-seq
MIRT2615904	hsa-miR-548n	CLIP-seq
MIRT2320076	hsa-miR-548x	CLIP-seq
MIRT2320078	hsa-miR-587	CLIP-seq
MIRT2095613	hsa-miR-603	CLIP-seq
MIRT2320080	hsa-miR-628-5p	CLIP-seq
MIRT2615906	hsa-miR-642a	CLIP-seq
MIRT1322074	hsa-miR-654-5p	CLIP-seq
MIRT2615907	hsa-miR-657	CLIP-seq
MIRT1322077	hsa-miR-767-3p	CLIP-seq
MIRT1322078	hsa-miR-873	CLIP-seq
MIRT1322080	hsa-miR-935	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
ATF6	Activation	17191123
DDIT3	Activation	17191123

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	15286784, 16189514, 16965550, 19364499, 21044950, 21976701, 25416956, 26871637, 29892012, 31515488, 32296183, 33961781, 35271311
GO:0005615	Component	Extracellular space	TAS	10331947
GO:0005783	Component	Endoplasmic reticulum	IDA	15286784
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	24262037
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IDA	15286784
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0007420	Process	Brain development	IBA
GO:0014069	Component	Postsynaptic density	IBA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0030182	Process	Neuron differentiation	IBA
GO:0043005	Component	Neuron projection	IBA
GO:0045202	Component	Synapse	IEA
GO:0071786	Process	Endoplasmic reticulum tubular network organization	IMP	18779370
GO:0071787	Process	Endoplasmic reticulum tubular network formation	IBA
GO:0071787	Process	Endoplasmic reticulum tubular network formation	IDA	25612671
GO:0071787	Process	Endoplasmic reticulum tubular network formation	IEA
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	15286784
GO:1902430	Process	Negative regulation of amyloid-beta formation	IEA
GO:1990809	Process	Endoplasmic reticulum tubular network membrane organization	IBA

Other IDs

• MIM: 604249
• HGNC: 10469
• e!Ensembl: ENSG00000133318

Protein

• UniProt ID: O95197
• Protein name: Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII)
• Protein function: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasm
• PDB: 7BRU
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02453	Reticulon	844 → 1008	Reticulon	Family

• Tissue specificity: TISSUE SPECIFICITY: Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at hig
• Sequence:

  MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
  LFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
  HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
  DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
  KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
  EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
  KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
  VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
  MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
  EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
  EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
  TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
  EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
  APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
  DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
  QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKL
  AVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQ
  AKLPGIAKKKAE

• Sequence length: 1032

Pathways

KEGG:

Alzheimer disease

Reactome:

Synaptic adhesion-like molecules

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
UTERINE FIBROID	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	17699523, 34668150	Associate	★☆☆☆☆ Found in Text Mining only
Amyloidosis	Amyloidosis	BEFREE	27883331		★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	BEFREE	24934404		★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	28589496		★☆☆☆☆ Found in Text Mining only
Bipolar I disorder	Bipolar Disorder	BEFREE	18466881, 23032943		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28717245	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	26909918	Associate	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Ischemic stroke	Pubtator	23466835	Inhibit	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Ischemic stroke	Pubtator	23466835	Associate	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	28238655		★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	28424902		★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	28238655		★☆☆☆☆ Found in Text Mining only
Lewy Body Disease	Lewy body disease	Pubtator	20374499	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28440552, 30282074		★☆☆☆☆ Found in Text Mining only
Lupus Nephritis	Lupus Nephritis	BEFREE	28120479		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	30282074		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	31358530		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of skin	Skin cancer	BEFREE	29507878		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	29507878		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29404549, 29507878		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	20374499	Associate	★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	29716941		★☆☆☆☆ Found in Text Mining only
Nonorganic psychosis	Nonorganic Psychosis	BEFREE	19786960		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	29716941		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	35331286	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	31358530		★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Psychosis	BEFREE	19786960, 23032943		★☆☆☆☆ Found in Text Mining only
Schizoaffective Disorder	Schizoaffective Disorder	BEFREE	19786960		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	11972448, 16081509, 16687441, 18282690, 19786960		★☆☆☆☆ Found in Text Mining only
Senile Plaques	Senile Plaques	BEFREE	27883331, 28733667, 29356939		★☆☆☆☆ Found in Text Mining only