Gene Gene information from NCBI Gene database.
Entrez ID 10308
Gene name Zinc finger protein 267
Gene symbol ZNF267
Synonyms (NCBI Gene)
HZF2
Chromosome 16
Chromosome location 16p11.2
miRNA miRNA information provided by mirtarbase database.
225
miRTarBase ID miRNA Experiments Reference
MIRT024601 hsa-miR-215-5p Microarray 19074876
MIRT026878 hsa-miR-192-5p Microarray 19074876
MIRT027813 hsa-miR-98-5p Microarray 19088304
MIRT686224 hsa-miR-23c HITS-CLIP 23313552
MIRT686223 hsa-miR-23b-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0006355 Process Regulation of DNA-templated transcription IEA
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604752 13060 ENSG00000185947
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q14586
Protein name Zinc finger protein 267 (Zinc finger protein HZF2)
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 3 44 KRAB box Family
PF00096 zf-C2H2 380 402 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 408 430 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 436 458 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 464 486 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 492 514 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 548 570 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 576 598 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 604 626 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 632 654 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 660 682 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 688 710 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 716 738 Zinc finger, C2H2 type Domain
Sequence
MGLLTFRDVAVEFSLEEWEHLEPAQKNLYQDVMLENYRNLVSLGLVVSKPDLITFLEQRK
EPWNVKSEETVAIQPDVFSHYNKDLLTEHCTEASFQKVISRRHGSCDLENLHLRKRWKRE
ECEGHNGCYDEKTFKYDQFDESSVESLFHQQILSSCAKSYNFDQYRKVFTHSSLLNQQEE
IDIWGKHHIYDKTSVLFRQVSTLNSYRNVFIGEKNYHCNNSEKTLNQSSSPKNHQENYFL
EKQYKCKEFEEVFLQSMHGQEKQEQSYKCNKCVEVCTQSLKHIQHQTIHIRENSYSYNKY
DKDLSQSSNLRKQIIHNEEKPYKCEKCGDSLNHSLHLTQHQIIPTEEKPCKWKECGKVFN
LNCSLYLTKQQQIDTGENLYKCKACSKSFTRSSNLIVHQRIHTGEKPYKCKECGKAFRCS
SYLTKHKRIH
TGEKPYKCKECGKAFNRSSCLTQHQTTHTGEKLYKCKVCSKSYARSSNLI
MHQRVH
TGEKPYKCKECGKVFSRSSCLTQHRKIHTGENLYKCKVCAKPFTCFSNLIVHER
IHTGEKPYKCKECGKAFPYSSHLIRHHRIHTGEKPYKCKACSKSFSDSSGLTVHRRTHTG
EKPYTCKECGKAFSYSSDVIQHRRIHTGQRPYKCEECGKAFNYRSYLTTHQRSHTGERPY
KCEECGKAFNSRSYLTTHRRRH
TGERPYKCDECGKAFSYRSYLTTHRRSHSGERPYKCEE
CGKAFNSRSYLIAHQRSH
TREKL
Sequence length 743
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
COLOR VISION DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DERMATOLOGIC DISORDERS Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS CTD, Disgenet
CTD, Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SKIN DISEASES CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Arsenic Encephalopathy Arsenic Encephalopathy CTD_human_DG 16835338
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 21840307 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 22076166 Stimulate
★☆☆☆☆
Found in Text Mining only
Cirrhosis Cirrhosis BEFREE 21840307
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 36691044 Associate
★☆☆☆☆
Found in Text Mining only
Dementia Dementia Pubtator 34194426 Associate
★☆☆☆☆
Found in Text Mining only
Dermatologic disorders Dermatologic Disorders CTD_human_DG 16835338
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Fibrosis, Liver Liver Fibrosis BEFREE 15814297
★☆☆☆☆
Found in Text Mining only
Hypoxia Hypoxia Pubtator 21840307 Stimulate
★☆☆☆☆
Found in Text Mining only
Liver carcinoma Liver carcinoma BEFREE 21840307, 22076166
★☆☆☆☆
Found in Text Mining only