Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10282
Gene name	Bet1 golgi vesicular membrane trafficking protein
Gene symbol	BET1
Synonyms (NCBI Gene)	HBET1MDRP
Chromosome	7
Chromosome location	7q21.3
Summary	This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein recepto

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001564	hsa-miR-155-5p	pSILAC	18668040
MIRT001564	hsa-miR-155-5p	Proteomics;Other	18668040
MIRT037591	hsa-miR-744-5p	CLASH	23622248
MIRT820976	hsa-miR-1252	CLIP-seq
MIRT820977	hsa-miR-128	CLIP-seq
MIRT820978	hsa-miR-1297	CLIP-seq
MIRT820979	hsa-miR-1305	CLIP-seq
MIRT820980	hsa-miR-144	CLIP-seq
MIRT820981	hsa-miR-153	CLIP-seq
MIRT820982	hsa-miR-214	CLIP-seq
MIRT820983	hsa-miR-2355-3p	CLIP-seq
MIRT820984	hsa-miR-23a	CLIP-seq
MIRT820985	hsa-miR-23b	CLIP-seq
MIRT820986	hsa-miR-23c	CLIP-seq
MIRT820987	hsa-miR-26a	CLIP-seq
MIRT820988	hsa-miR-26b	CLIP-seq
MIRT820989	hsa-miR-3064-3p	CLIP-seq
MIRT820990	hsa-miR-3148	CLIP-seq
MIRT820991	hsa-miR-3166	CLIP-seq
MIRT820992	hsa-miR-3611	CLIP-seq
MIRT820993	hsa-miR-3619-5p	CLIP-seq
MIRT820994	hsa-miR-3655	CLIP-seq
MIRT820995	hsa-miR-3668	CLIP-seq
MIRT820996	hsa-miR-3688-3p	CLIP-seq
MIRT820997	hsa-miR-4291	CLIP-seq
MIRT820998	hsa-miR-431	CLIP-seq
MIRT820999	hsa-miR-4465	CLIP-seq
MIRT821000	hsa-miR-448	CLIP-seq
MIRT821001	hsa-miR-4682	CLIP-seq
MIRT821002	hsa-miR-4714-3p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT821004	hsa-miR-4778-5p	CLIP-seq
MIRT821005	hsa-miR-511	CLIP-seq
MIRT821006	hsa-miR-578	CLIP-seq
MIRT821007	hsa-miR-587	CLIP-seq
MIRT821008	hsa-miR-676	CLIP-seq
MIRT821009	hsa-miR-761	CLIP-seq
MIRT821010	hsa-miR-922	CLIP-seq
MIRT1942632	hsa-miR-1236	CLIP-seq
MIRT1942633	hsa-miR-1237	CLIP-seq
MIRT1942634	hsa-miR-1248	CLIP-seq
MIRT820981	hsa-miR-153	CLIP-seq
MIRT1942635	hsa-miR-3647-3p	CLIP-seq
MIRT1942636	hsa-miR-3662	CLIP-seq
MIRT821000	hsa-miR-448	CLIP-seq
MIRT1942637	hsa-miR-4659a-5p	CLIP-seq
MIRT1942638	hsa-miR-4659b-5p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT1942639	hsa-miR-4753-3p	CLIP-seq
MIRT1942640	hsa-miR-4776-3p	CLIP-seq
MIRT1942641	hsa-miR-767-3p	CLIP-seq
MIRT1942642	hsa-miR-9	CLIP-seq
MIRT1942643	hsa-miR-942	CLIP-seq
MIRT2181426	hsa-miR-1257	CLIP-seq
MIRT820980	hsa-miR-144	CLIP-seq
MIRT820983	hsa-miR-2355-3p	CLIP-seq
MIRT2181427	hsa-miR-3155	CLIP-seq
MIRT2181428	hsa-miR-3155b	CLIP-seq
MIRT2181429	hsa-miR-3165	CLIP-seq
MIRT2181430	hsa-miR-335	CLIP-seq
MIRT1942635	hsa-miR-3647-3p	CLIP-seq
MIRT820994	hsa-miR-3655	CLIP-seq
MIRT2181431	hsa-miR-3670	CLIP-seq
MIRT2181432	hsa-miR-3925-3p	CLIP-seq
MIRT2181433	hsa-miR-4275	CLIP-seq
MIRT820998	hsa-miR-431	CLIP-seq
MIRT2181434	hsa-miR-4645-5p	CLIP-seq
MIRT2181435	hsa-miR-4673	CLIP-seq
MIRT821002	hsa-miR-4714-3p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT821004	hsa-miR-4778-5p	CLIP-seq
MIRT2181436	hsa-miR-4790-3p	CLIP-seq
MIRT2181437	hsa-miR-484	CLIP-seq
MIRT2181438	hsa-miR-491-3p	CLIP-seq
MIRT821005	hsa-miR-511	CLIP-seq
MIRT821008	hsa-miR-676	CLIP-seq
MIRT2181439	hsa-miR-759	CLIP-seq
MIRT2181440	hsa-miR-766	CLIP-seq
MIRT820980	hsa-miR-144	CLIP-seq
MIRT2426619	hsa-miR-3129-3p	CLIP-seq
MIRT2426620	hsa-miR-4272	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT2426621	hsa-miR-4742-3p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT2484687	hsa-miR-142-5p	CLIP-seq
MIRT2484688	hsa-miR-182	CLIP-seq
MIRT2484689	hsa-miR-186	CLIP-seq
MIRT2484690	hsa-miR-19a	CLIP-seq
MIRT2484691	hsa-miR-19b	CLIP-seq
MIRT2484692	hsa-miR-296-5p	CLIP-seq
MIRT2484693	hsa-miR-3123	CLIP-seq
MIRT2484694	hsa-miR-3133	CLIP-seq
MIRT2484695	hsa-miR-3162-3p	CLIP-seq
MIRT2484696	hsa-miR-3184	CLIP-seq
MIRT2181430	hsa-miR-335	CLIP-seq
MIRT2484697	hsa-miR-3613-3p	CLIP-seq
MIRT1942635	hsa-miR-3647-3p	CLIP-seq
MIRT820995	hsa-miR-3668	CLIP-seq
MIRT2484698	hsa-miR-3681	CLIP-seq
MIRT2484699	hsa-miR-3691-3p	CLIP-seq
MIRT2484700	hsa-miR-423-5p	CLIP-seq
MIRT2484701	hsa-miR-4460	CLIP-seq
MIRT2484702	hsa-miR-4470	CLIP-seq
MIRT2484703	hsa-miR-4476	CLIP-seq
MIRT2484704	hsa-miR-4480	CLIP-seq
MIRT2484705	hsa-miR-4489	CLIP-seq
MIRT2484706	hsa-miR-4517	CLIP-seq
MIRT2484707	hsa-miR-4528	CLIP-seq
MIRT2484708	hsa-miR-4643	CLIP-seq
MIRT2484709	hsa-miR-4645-3p	CLIP-seq
MIRT2484710	hsa-miR-466	CLIP-seq
MIRT2484711	hsa-miR-4688	CLIP-seq
MIRT2484712	hsa-miR-4699-5p	CLIP-seq
MIRT2484713	hsa-miR-4715-5p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT2484714	hsa-miR-4727-3p	CLIP-seq
MIRT2484715	hsa-miR-4760-3p	CLIP-seq
MIRT2484716	hsa-miR-4789-3p	CLIP-seq
MIRT2484717	hsa-miR-495	CLIP-seq
MIRT2484718	hsa-miR-508-3p	CLIP-seq
MIRT2484719	hsa-miR-548a-3p	CLIP-seq
MIRT2484720	hsa-miR-548c-3p	CLIP-seq
MIRT2484721	hsa-miR-548e	CLIP-seq
MIRT2484722	hsa-miR-548f	CLIP-seq
MIRT2484723	hsa-miR-561	CLIP-seq
MIRT2484724	hsa-miR-875-3p	CLIP-seq
MIRT2484725	hsa-miR-889	CLIP-seq
MIRT1942642	hsa-miR-9	CLIP-seq
MIRT2484726	hsa-miR-944	CLIP-seq
MIRT2484687	hsa-miR-142-5p	CLIP-seq
MIRT2484688	hsa-miR-182	CLIP-seq
MIRT2484689	hsa-miR-186	CLIP-seq
MIRT2484690	hsa-miR-19a	CLIP-seq
MIRT2484691	hsa-miR-19b	CLIP-seq
MIRT2484692	hsa-miR-296-5p	CLIP-seq
MIRT2484693	hsa-miR-3123	CLIP-seq
MIRT2484694	hsa-miR-3133	CLIP-seq
MIRT2484695	hsa-miR-3162-3p	CLIP-seq
MIRT2484696	hsa-miR-3184	CLIP-seq
MIRT2181430	hsa-miR-335	CLIP-seq
MIRT2484697	hsa-miR-3613-3p	CLIP-seq
MIRT820995	hsa-miR-3668	CLIP-seq
MIRT2484699	hsa-miR-3691-3p	CLIP-seq
MIRT2484700	hsa-miR-423-5p	CLIP-seq
MIRT2484702	hsa-miR-4470	CLIP-seq
MIRT2484703	hsa-miR-4476	CLIP-seq
MIRT2484704	hsa-miR-4480	CLIP-seq
MIRT2484706	hsa-miR-4517	CLIP-seq
MIRT2484707	hsa-miR-4528	CLIP-seq
MIRT2484708	hsa-miR-4643	CLIP-seq
MIRT2484709	hsa-miR-4645-3p	CLIP-seq
MIRT2484710	hsa-miR-466	CLIP-seq
MIRT2484712	hsa-miR-4699-5p	CLIP-seq
MIRT2484713	hsa-miR-4715-5p	CLIP-seq
MIRT821003	hsa-miR-4719	CLIP-seq
MIRT2484715	hsa-miR-4760-3p	CLIP-seq
MIRT2484716	hsa-miR-4789-3p	CLIP-seq
MIRT2484717	hsa-miR-495	CLIP-seq
MIRT2484718	hsa-miR-508-3p	CLIP-seq
MIRT2484719	hsa-miR-548a-3p	CLIP-seq
MIRT2484720	hsa-miR-548c-3p	CLIP-seq
MIRT2484721	hsa-miR-548e	CLIP-seq
MIRT2484722	hsa-miR-548f	CLIP-seq
MIRT2484723	hsa-miR-561	CLIP-seq
MIRT2484724	hsa-miR-875-3p	CLIP-seq
MIRT2484725	hsa-miR-889	CLIP-seq
MIRT1942642	hsa-miR-9	CLIP-seq
MIRT2484726	hsa-miR-944	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS	8621431
GO:0005484	Function	SNAP receptor activity	IBA
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 29568061, 32296183, 32814053, 33961781, 34779586, 35271311
GO:0005783	Component	Endoplasmic reticulum	IDA	34779586
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005801	Component	Cis-Golgi network	IDA	34779586
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	34779586
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0030133	Component	Transport vesicle	TAS
GO:0031201	Component	SNARE complex	IBA
GO:0033116	Component	Endoplasmic reticulum-Golgi intermediate compartment membrane	TAS
GO:0048280	Process	Vesicle fusion with Golgi apparatus	IBA

MIM	HGNC	e!Ensembl
605456	14562	ENSG00000105829

O15155

Protein name

BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)

Protein function

Required for vesicular transport from the ER to the Golgi complex (PubMed:34779586). Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity). {ECO:0000250|UniProtKB:Q62896, ECO:0000

PDB

3EGX

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in muscle. {ECO:0000269|PubMed:34779586}.

Sequence

MRRAGLGEGVPPGNYGNYGYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQ
NKLLAEMDSQFDSTTGFLGKTMGKLKILSRGSQTKLLCYMMLFSLFVFFIIYWIIKLR

Sequence length

118

Interactions

View interactions

	KEGG		Reactome
	SNARE interactions in vesicular transport		COPII-mediated vesicle transport COPI-mediated anterograde transport

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BRCAX BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Muscular dystrophy, congenital, with rapid progression	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Progressive muscle weakness	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Seizure	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Coronary Syndrome	Coronary Syndrome	BEFREE	28341793, 29170295		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute pancreatitis	Pancreatitis	BEFREE	28827292		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial Fibrillation	BEFREE	30463886		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bronchiolitis	Bronchiolitis	BEFREE	30940682		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	Pubtator	34779586	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	29559542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Unverricht-Lundborg Syndrome	Myoclonic Epilepsy	BEFREE	28982678		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Fibroids	Uterine Fibroids	BEFREE	23892540		★★★★★ ★☆☆☆☆ Found in Text Mining only

BET1 (Bet1 golgi vesicular membrane trafficking protein)