Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10130
Gene name	Protein disulfide isomerase family A member 6
Gene symbol	PDIA6
Synonyms (NCBI Gene)	ERP5P5TXNDC7
Chromosome	2
Chromosome location	2p25.1
Summary	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically

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miRTarBase ID	miRNA	Experiments	Reference
MIRT031810	hsa-miR-16-5p	Proteomics	18668040
MIRT035870	hsa-miR-1304-5p	CLASH	23622248
MIRT035802	hsa-miR-1909-3p	CLASH	23622248
MIRT437628	hsa-miR-150-5p	MicroarrayqRT-PCR	22815788
MIRT437663	hsa-miR-195-5p	MicroarrayqRT-PCR	22815788
MIRT574542	hsa-miR-15a-5p	HITS-CLIP	23313552
MIRT574541	hsa-miR-15b-5p	HITS-CLIP	23313552
MIRT574540	hsa-miR-497-5p	HITS-CLIP	23313552
MIRT574539	hsa-miR-424-5p	HITS-CLIP	23313552
MIRT437663	hsa-miR-195-5p	HITS-CLIP	23313552
MIRT031810	hsa-miR-16-5p	HITS-CLIP	23313552
MIRT574538	hsa-miR-6838-5p	HITS-CLIP	23313552
MIRT202709	hsa-miR-181a-5p	HITS-CLIP	23313552
MIRT202710	hsa-miR-181b-5p	HITS-CLIP	23313552
MIRT202713	hsa-miR-4262	HITS-CLIP	23313552
MIRT202712	hsa-miR-181d-5p	HITS-CLIP	23313552
MIRT202711	hsa-miR-181c-5p	HITS-CLIP	23313552
MIRT084418	hsa-miR-543	HITS-CLIP	23313552
MIRT574536	hsa-miR-4274	HITS-CLIP	23313552
MIRT574535	hsa-miR-3919	HITS-CLIP	23313552
MIRT574534	hsa-miR-4756-3p	HITS-CLIP	23313552
MIRT574533	hsa-miR-196b-3p	HITS-CLIP	23313552
MIRT700975	hsa-miR-5695	HITS-CLIP	23313552
MIRT700974	hsa-miR-4480	HITS-CLIP	23313552
MIRT574531	hsa-miR-5705	HITS-CLIP	23313552
MIRT574532	hsa-miR-498	HITS-CLIP	23313552
MIRT630667	hsa-miR-145-3p	HITS-CLIP	23824327
MIRT630666	hsa-miR-376a-5p	HITS-CLIP	23824327
MIRT630667	hsa-miR-145-3p	HITS-CLIP	23824327
MIRT630666	hsa-miR-376a-5p	HITS-CLIP	23824327
MIRT574542	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT574541	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT574540	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT574539	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT437663	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT031810	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT574538	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT574537	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT574536	hsa-miR-4274	PAR-CLIP	20371350
MIRT574535	hsa-miR-3919	PAR-CLIP	20371350
MIRT574534	hsa-miR-4756-3p	PAR-CLIP	20371350
MIRT574533	hsa-miR-196b-3p	PAR-CLIP	20371350
MIRT574531	hsa-miR-5705	PAR-CLIP	20371350
MIRT574532	hsa-miR-498	PAR-CLIP	20371350
MIRT471442	hsa-miR-23b-3p	PAR-CLIP	23592263
MIRT471441	hsa-miR-23c	PAR-CLIP	23592263
MIRT471440	hsa-miR-23a-3p	PAR-CLIP	23592263
MIRT471439	hsa-miR-130a-5p	PAR-CLIP	23592263
MIRT471438	hsa-miR-548ac	PAR-CLIP	23592263
MIRT471437	hsa-miR-548bb-3p	PAR-CLIP	23592263
MIRT471436	hsa-miR-548d-3p	PAR-CLIP	23592263
MIRT471435	hsa-miR-548h-3p	PAR-CLIP	23592263
MIRT471434	hsa-miR-548z	PAR-CLIP	23592263
MIRT471433	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT471432	hsa-miR-3646	PAR-CLIP	23592263
MIRT471431	hsa-miR-1273d	PAR-CLIP	23592263
MIRT471430	hsa-miR-6074	PAR-CLIP	23592263
MIRT471429	hsa-miR-4272	PAR-CLIP	23592263
MIRT471428	hsa-miR-105-5p	PAR-CLIP	23592263
MIRT471427	hsa-miR-7853-5p	PAR-CLIP	23592263
MIRT350659	hsa-miR-7515	PAR-CLIP	23592263
MIRT471426	hsa-miR-3179	PAR-CLIP	23592263
MIRT471425	hsa-miR-3671	PAR-CLIP	23592263
MIRT350658	hsa-miR-6864-5p	PAR-CLIP	23592263
MIRT471424	hsa-miR-607	PAR-CLIP	23592263
MIRT440012	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440012	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT574542	hsa-miR-15a-5p	HITS-CLIP	23313552
MIRT574541	hsa-miR-15b-5p	HITS-CLIP	23313552
MIRT574540	hsa-miR-497-5p	HITS-CLIP	23313552
MIRT574539	hsa-miR-424-5p	HITS-CLIP	23313552
MIRT437663	hsa-miR-195-5p	HITS-CLIP	23313552
MIRT031810	hsa-miR-16-5p	HITS-CLIP	23313552
MIRT574538	hsa-miR-6838-5p	HITS-CLIP	23313552
MIRT202709	hsa-miR-181a-5p	HITS-CLIP	23313552
MIRT202710	hsa-miR-181b-5p	HITS-CLIP	23313552
MIRT202713	hsa-miR-4262	HITS-CLIP	23313552
MIRT202712	hsa-miR-181d-5p	HITS-CLIP	23313552
MIRT202711	hsa-miR-181c-5p	HITS-CLIP	23313552
MIRT084418	hsa-miR-543	HITS-CLIP	23313552
MIRT574536	hsa-miR-4274	HITS-CLIP	23313552
MIRT574535	hsa-miR-3919	HITS-CLIP	23313552
MIRT574534	hsa-miR-4756-3p	HITS-CLIP	23313552
MIRT574533	hsa-miR-196b-3p	HITS-CLIP	23313552
MIRT700975	hsa-miR-5695	HITS-CLIP	23313552
MIRT700974	hsa-miR-4480	HITS-CLIP	23313552
MIRT574531	hsa-miR-5705	HITS-CLIP	23313552
MIRT574532	hsa-miR-498	HITS-CLIP	23313552
MIRT630667	hsa-miR-145-3p	HITS-CLIP	23824327
MIRT630666	hsa-miR-376a-5p	HITS-CLIP	23824327
MIRT630667	hsa-miR-145-3p	HITS-CLIP	23824327
MIRT630666	hsa-miR-376a-5p	HITS-CLIP	23824327
MIRT574542	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT574541	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT574540	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT574539	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT437663	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT031810	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT574538	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT574537	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT574536	hsa-miR-4274	PAR-CLIP	20371350
MIRT574535	hsa-miR-3919	PAR-CLIP	20371350
MIRT574534	hsa-miR-4756-3p	PAR-CLIP	20371350
MIRT574533	hsa-miR-196b-3p	PAR-CLIP	20371350
MIRT574531	hsa-miR-5705	PAR-CLIP	20371350
MIRT574532	hsa-miR-498	PAR-CLIP	20371350
MIRT471442	hsa-miR-23b-3p	PAR-CLIP	23592263
MIRT471441	hsa-miR-23c	PAR-CLIP	23592263
MIRT471440	hsa-miR-23a-3p	PAR-CLIP	23592263
MIRT471439	hsa-miR-130a-5p	PAR-CLIP	23592263
MIRT471438	hsa-miR-548ac	PAR-CLIP	23592263
MIRT471437	hsa-miR-548bb-3p	PAR-CLIP	23592263
MIRT471436	hsa-miR-548d-3p	PAR-CLIP	23592263
MIRT471435	hsa-miR-548h-3p	PAR-CLIP	23592263
MIRT471434	hsa-miR-548z	PAR-CLIP	23592263
MIRT471433	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT471432	hsa-miR-3646	PAR-CLIP	23592263
MIRT471431	hsa-miR-1273d	PAR-CLIP	23592263
MIRT471430	hsa-miR-6074	PAR-CLIP	23592263
MIRT471429	hsa-miR-4272	PAR-CLIP	23592263
MIRT471428	hsa-miR-105-5p	PAR-CLIP	23592263
MIRT471427	hsa-miR-7853-5p	PAR-CLIP	23592263
MIRT350659	hsa-miR-7515	PAR-CLIP	23592263
MIRT471426	hsa-miR-3179	PAR-CLIP	23592263
MIRT471425	hsa-miR-3671	PAR-CLIP	23592263
MIRT350658	hsa-miR-6864-5p	PAR-CLIP	23592263
MIRT471424	hsa-miR-607	PAR-CLIP	23592263
MIRT1221493	hsa-miR-105	CLIP-seq
MIRT1221494	hsa-miR-1229	CLIP-seq
MIRT1221495	hsa-miR-1273f	CLIP-seq
MIRT1221496	hsa-miR-1297	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT1221498	hsa-miR-143	CLIP-seq
MIRT1221499	hsa-miR-15a	CLIP-seq
MIRT1221500	hsa-miR-15b	CLIP-seq
MIRT1221501	hsa-miR-16	CLIP-seq
MIRT1221502	hsa-miR-181a	CLIP-seq
MIRT1221503	hsa-miR-181b	CLIP-seq
MIRT1221504	hsa-miR-181c	CLIP-seq
MIRT1221505	hsa-miR-181d	CLIP-seq
MIRT1221506	hsa-miR-195	CLIP-seq
MIRT1221507	hsa-miR-23a	CLIP-seq
MIRT1221508	hsa-miR-23b	CLIP-seq
MIRT1221509	hsa-miR-26a	CLIP-seq
MIRT1221510	hsa-miR-26b	CLIP-seq
MIRT1221511	hsa-miR-3121-5p	CLIP-seq
MIRT1221512	hsa-miR-3148	CLIP-seq
MIRT1221513	hsa-miR-34c-3p	CLIP-seq
MIRT1221514	hsa-miR-3617	CLIP-seq
MIRT1221515	hsa-miR-3682-5p	CLIP-seq
MIRT1221516	hsa-miR-3688-3p	CLIP-seq
MIRT1221517	hsa-miR-376a	CLIP-seq
MIRT1221518	hsa-miR-376b	CLIP-seq
MIRT1221519	hsa-miR-424	CLIP-seq
MIRT1221520	hsa-miR-4252	CLIP-seq
MIRT1221521	hsa-miR-4277	CLIP-seq
MIRT1221522	hsa-miR-4307	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221524	hsa-miR-4427	CLIP-seq
MIRT1221525	hsa-miR-4465	CLIP-seq
MIRT1221526	hsa-miR-4501	CLIP-seq
MIRT1221527	hsa-miR-4504	CLIP-seq
MIRT1221528	hsa-miR-4639-3p	CLIP-seq
MIRT1221529	hsa-miR-4659a-3p	CLIP-seq
MIRT1221530	hsa-miR-4659b-3p	CLIP-seq
MIRT1221531	hsa-miR-4680-3p	CLIP-seq
MIRT1221532	hsa-miR-4690-3p	CLIP-seq
MIRT1221533	hsa-miR-4698	CLIP-seq
MIRT1221534	hsa-miR-4699-3p	CLIP-seq
MIRT1221535	hsa-miR-4708-5p	CLIP-seq
MIRT1221536	hsa-miR-4714-5p	CLIP-seq
MIRT1221537	hsa-miR-4717-5p	CLIP-seq
MIRT1221538	hsa-miR-4753-5p	CLIP-seq
MIRT1221539	hsa-miR-4760-3p	CLIP-seq
MIRT1221540	hsa-miR-4770	CLIP-seq
MIRT1221541	hsa-miR-497	CLIP-seq
MIRT1221542	hsa-miR-499-3p	CLIP-seq
MIRT1221543	hsa-miR-499a-3p	CLIP-seq
MIRT1221544	hsa-miR-513c	CLIP-seq
MIRT1221545	hsa-miR-514b-5p	CLIP-seq
MIRT1221546	hsa-miR-526b	CLIP-seq
MIRT1221547	hsa-miR-542-3p	CLIP-seq
MIRT1221548	hsa-miR-578	CLIP-seq
MIRT1221549	hsa-miR-641	CLIP-seq
MIRT1221550	hsa-miR-656	CLIP-seq
MIRT1221551	hsa-miR-889	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221493	hsa-miR-105	CLIP-seq
MIRT2063905	hsa-miR-1208	CLIP-seq
MIRT2063906	hsa-miR-1225-3p	CLIP-seq
MIRT1221494	hsa-miR-1229	CLIP-seq
MIRT2063907	hsa-miR-1233	CLIP-seq
MIRT2063908	hsa-miR-1256	CLIP-seq
MIRT2063909	hsa-miR-1267	CLIP-seq
MIRT2063910	hsa-miR-1272	CLIP-seq
MIRT1221495	hsa-miR-1273f	CLIP-seq
MIRT2063911	hsa-miR-1287	CLIP-seq
MIRT1221496	hsa-miR-1297	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT2063912	hsa-miR-1322	CLIP-seq
MIRT1221498	hsa-miR-143	CLIP-seq
MIRT2063913	hsa-miR-150	CLIP-seq
MIRT1221499	hsa-miR-15a	CLIP-seq
MIRT1221500	hsa-miR-15b	CLIP-seq
MIRT1221501	hsa-miR-16	CLIP-seq
MIRT1221502	hsa-miR-181a	CLIP-seq
MIRT1221503	hsa-miR-181b	CLIP-seq
MIRT1221504	hsa-miR-181c	CLIP-seq
MIRT1221505	hsa-miR-181d	CLIP-seq
MIRT1221506	hsa-miR-195	CLIP-seq
MIRT2063914	hsa-miR-216b	CLIP-seq
MIRT1221509	hsa-miR-26a	CLIP-seq
MIRT1221510	hsa-miR-26b	CLIP-seq
MIRT2063915	hsa-miR-3123	CLIP-seq
MIRT2063916	hsa-miR-3135b	CLIP-seq
MIRT1221512	hsa-miR-3148	CLIP-seq
MIRT2063917	hsa-miR-3200-5p	CLIP-seq
MIRT2063918	hsa-miR-337-5p	CLIP-seq
MIRT2063919	hsa-miR-338-5p	CLIP-seq
MIRT2063920	hsa-miR-3529	CLIP-seq
MIRT2063921	hsa-miR-3659	CLIP-seq
MIRT1221515	hsa-miR-3682-5p	CLIP-seq
MIRT2063922	hsa-miR-370	CLIP-seq
MIRT2063923	hsa-miR-379	CLIP-seq
MIRT2063924	hsa-miR-3925-5p	CLIP-seq
MIRT2063925	hsa-miR-3940-3p	CLIP-seq
MIRT2063926	hsa-miR-3945	CLIP-seq
MIRT1221519	hsa-miR-424	CLIP-seq
MIRT1221520	hsa-miR-4252	CLIP-seq
MIRT2063927	hsa-miR-4253	CLIP-seq
MIRT1221521	hsa-miR-4277	CLIP-seq
MIRT2063928	hsa-miR-4280	CLIP-seq
MIRT2063929	hsa-miR-4304	CLIP-seq
MIRT1221522	hsa-miR-4307	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221524	hsa-miR-4427	CLIP-seq
MIRT2063930	hsa-miR-4451	CLIP-seq
MIRT1221525	hsa-miR-4465	CLIP-seq
MIRT2063931	hsa-miR-4485	CLIP-seq
MIRT2063932	hsa-miR-4495	CLIP-seq
MIRT1221526	hsa-miR-4501	CLIP-seq
MIRT2063933	hsa-miR-4527	CLIP-seq
MIRT1221528	hsa-miR-4639-3p	CLIP-seq
MIRT2063934	hsa-miR-4650-3p	CLIP-seq
MIRT2063935	hsa-miR-4658	CLIP-seq
MIRT1221529	hsa-miR-4659a-3p	CLIP-seq
MIRT1221530	hsa-miR-4659b-3p	CLIP-seq
MIRT2063936	hsa-miR-4668-3p	CLIP-seq
MIRT1221531	hsa-miR-4680-3p	CLIP-seq
MIRT2063937	hsa-miR-4682	CLIP-seq
MIRT2063938	hsa-miR-4684-3p	CLIP-seq
MIRT1221532	hsa-miR-4690-3p	CLIP-seq
MIRT1221533	hsa-miR-4698	CLIP-seq
MIRT1221534	hsa-miR-4699-3p	CLIP-seq
MIRT1221535	hsa-miR-4708-5p	CLIP-seq
MIRT1221536	hsa-miR-4714-5p	CLIP-seq
MIRT2063939	hsa-miR-4716-5p	CLIP-seq
MIRT1221537	hsa-miR-4717-5p	CLIP-seq
MIRT2063940	hsa-miR-4718	CLIP-seq
MIRT2063941	hsa-miR-4732-5p	CLIP-seq
MIRT2063942	hsa-miR-4742-3p	CLIP-seq
MIRT1221538	hsa-miR-4753-5p	CLIP-seq
MIRT1221540	hsa-miR-4770	CLIP-seq
MIRT2063943	hsa-miR-4786-3p	CLIP-seq
MIRT2063944	hsa-miR-490-3p	CLIP-seq
MIRT1221541	hsa-miR-497	CLIP-seq
MIRT1221542	hsa-miR-499-3p	CLIP-seq
MIRT1221543	hsa-miR-499a-3p	CLIP-seq
MIRT2063945	hsa-miR-522	CLIP-seq
MIRT1221546	hsa-miR-526b	CLIP-seq
MIRT2063946	hsa-miR-541	CLIP-seq
MIRT2063947	hsa-miR-548c-3p	CLIP-seq
MIRT2063948	hsa-miR-574-5p	CLIP-seq
MIRT1221548	hsa-miR-578	CLIP-seq
MIRT2063949	hsa-miR-587	CLIP-seq
MIRT2063950	hsa-miR-649	CLIP-seq
MIRT2063951	hsa-miR-654-5p	CLIP-seq
MIRT1221550	hsa-miR-656	CLIP-seq
MIRT2063952	hsa-miR-875-3p	CLIP-seq
MIRT1221493	hsa-miR-105	CLIP-seq
MIRT2063905	hsa-miR-1208	CLIP-seq
MIRT1221496	hsa-miR-1297	CLIP-seq
MIRT2292409	hsa-miR-1304	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT2292410	hsa-miR-149	CLIP-seq
MIRT2063913	hsa-miR-150	CLIP-seq
MIRT1221499	hsa-miR-15a	CLIP-seq
MIRT1221500	hsa-miR-15b	CLIP-seq
MIRT1221501	hsa-miR-16	CLIP-seq
MIRT1221502	hsa-miR-181a	CLIP-seq
MIRT1221503	hsa-miR-181b	CLIP-seq
MIRT1221504	hsa-miR-181c	CLIP-seq
MIRT1221505	hsa-miR-181d	CLIP-seq
MIRT1221506	hsa-miR-195	CLIP-seq
MIRT1221509	hsa-miR-26a	CLIP-seq
MIRT1221510	hsa-miR-26b	CLIP-seq
MIRT1221515	hsa-miR-3682-5p	CLIP-seq
MIRT1221519	hsa-miR-424	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221524	hsa-miR-4427	CLIP-seq
MIRT1221525	hsa-miR-4465	CLIP-seq
MIRT1221526	hsa-miR-4501	CLIP-seq
MIRT1221527	hsa-miR-4504	CLIP-seq
MIRT1221528	hsa-miR-4639-3p	CLIP-seq
MIRT1221529	hsa-miR-4659a-3p	CLIP-seq
MIRT1221530	hsa-miR-4659b-3p	CLIP-seq
MIRT2063936	hsa-miR-4668-3p	CLIP-seq
MIRT1221531	hsa-miR-4680-3p	CLIP-seq
MIRT2063938	hsa-miR-4684-3p	CLIP-seq
MIRT1221532	hsa-miR-4690-3p	CLIP-seq
MIRT1221533	hsa-miR-4698	CLIP-seq
MIRT1221534	hsa-miR-4699-3p	CLIP-seq
MIRT1221536	hsa-miR-4714-5p	CLIP-seq
MIRT2063942	hsa-miR-4742-3p	CLIP-seq
MIRT1221541	hsa-miR-497	CLIP-seq
MIRT1221542	hsa-miR-499-3p	CLIP-seq
MIRT1221543	hsa-miR-499a-3p	CLIP-seq
MIRT1221547	hsa-miR-542-3p	CLIP-seq
MIRT2063947	hsa-miR-548c-3p	CLIP-seq
MIRT1221550	hsa-miR-656	CLIP-seq
MIRT2292411	hsa-miR-892b	CLIP-seq
MIRT1221494	hsa-miR-1229	CLIP-seq
MIRT1221499	hsa-miR-15a	CLIP-seq
MIRT1221500	hsa-miR-15b	CLIP-seq
MIRT1221501	hsa-miR-16	CLIP-seq
MIRT1221502	hsa-miR-181a	CLIP-seq
MIRT1221503	hsa-miR-181b	CLIP-seq
MIRT1221504	hsa-miR-181c	CLIP-seq
MIRT1221505	hsa-miR-181d	CLIP-seq
MIRT1221506	hsa-miR-195	CLIP-seq
MIRT1221519	hsa-miR-424	CLIP-seq
MIRT1221521	hsa-miR-4277	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221541	hsa-miR-497	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT1221499	hsa-miR-15a	CLIP-seq
MIRT1221500	hsa-miR-15b	CLIP-seq
MIRT1221501	hsa-miR-16	CLIP-seq
MIRT1221502	hsa-miR-181a	CLIP-seq
MIRT1221503	hsa-miR-181b	CLIP-seq
MIRT1221504	hsa-miR-181c	CLIP-seq
MIRT1221505	hsa-miR-181d	CLIP-seq
MIRT1221506	hsa-miR-195	CLIP-seq
MIRT1221517	hsa-miR-376a	CLIP-seq
MIRT1221518	hsa-miR-376b	CLIP-seq
MIRT1221519	hsa-miR-424	CLIP-seq
MIRT1221539	hsa-miR-4760-3p	CLIP-seq
MIRT1221541	hsa-miR-497	CLIP-seq
MIRT1221493	hsa-miR-105	CLIP-seq
MIRT2063905	hsa-miR-1208	CLIP-seq
MIRT2063906	hsa-miR-1225-3p	CLIP-seq
MIRT2063907	hsa-miR-1233	CLIP-seq
MIRT2063909	hsa-miR-1267	CLIP-seq
MIRT1221495	hsa-miR-1273f	CLIP-seq
MIRT2590514	hsa-miR-129-5p	CLIP-seq
MIRT1221496	hsa-miR-1297	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT2590515	hsa-miR-1323	CLIP-seq
MIRT1221498	hsa-miR-143	CLIP-seq
MIRT2063913	hsa-miR-150	CLIP-seq
MIRT2590516	hsa-miR-186	CLIP-seq
MIRT2063914	hsa-miR-216b	CLIP-seq
MIRT1221509	hsa-miR-26a	CLIP-seq
MIRT1221510	hsa-miR-26b	CLIP-seq
MIRT2590517	hsa-miR-3065-5p	CLIP-seq
MIRT1221511	hsa-miR-3121-5p	CLIP-seq
MIRT2590518	hsa-miR-3133	CLIP-seq
MIRT2590519	hsa-miR-3150a-3p	CLIP-seq
MIRT2590520	hsa-miR-3151	CLIP-seq
MIRT2590521	hsa-miR-3163	CLIP-seq
MIRT2590522	hsa-miR-3175	CLIP-seq
MIRT2063919	hsa-miR-338-5p	CLIP-seq
MIRT1221513	hsa-miR-34c-3p	CLIP-seq
MIRT2063920	hsa-miR-3529	CLIP-seq
MIRT1221514	hsa-miR-3617	CLIP-seq
MIRT2590523	hsa-miR-3662	CLIP-seq
MIRT1221515	hsa-miR-3682-5p	CLIP-seq
MIRT1221517	hsa-miR-376a	CLIP-seq
MIRT1221518	hsa-miR-376b	CLIP-seq
MIRT2063923	hsa-miR-379	CLIP-seq
MIRT2063925	hsa-miR-3940-3p	CLIP-seq
MIRT2063926	hsa-miR-3945	CLIP-seq
MIRT1221520	hsa-miR-4252	CLIP-seq
MIRT2063927	hsa-miR-4253	CLIP-seq
MIRT2590524	hsa-miR-4265	CLIP-seq
MIRT2590525	hsa-miR-4296	CLIP-seq
MIRT1221522	hsa-miR-4307	CLIP-seq
MIRT2590526	hsa-miR-4322	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221524	hsa-miR-4427	CLIP-seq
MIRT2590527	hsa-miR-4447	CLIP-seq
MIRT2063930	hsa-miR-4451	CLIP-seq
MIRT1221525	hsa-miR-4465	CLIP-seq
MIRT2590528	hsa-miR-4472	CLIP-seq
MIRT2590529	hsa-miR-4474-3p	CLIP-seq
MIRT2063932	hsa-miR-4495	CLIP-seq
MIRT2590530	hsa-miR-4509	CLIP-seq
MIRT2063933	hsa-miR-4527	CLIP-seq
MIRT1221528	hsa-miR-4639-3p	CLIP-seq
MIRT2590531	hsa-miR-4645-3p	CLIP-seq
MIRT2063934	hsa-miR-4650-3p	CLIP-seq
MIRT2063936	hsa-miR-4668-3p	CLIP-seq
MIRT1221531	hsa-miR-4680-3p	CLIP-seq
MIRT2063938	hsa-miR-4684-3p	CLIP-seq
MIRT1221533	hsa-miR-4698	CLIP-seq
MIRT1221534	hsa-miR-4699-3p	CLIP-seq
MIRT1221535	hsa-miR-4708-5p	CLIP-seq
MIRT1221536	hsa-miR-4714-5p	CLIP-seq
MIRT2063939	hsa-miR-4716-5p	CLIP-seq
MIRT1221537	hsa-miR-4717-5p	CLIP-seq
MIRT2590532	hsa-miR-4744	CLIP-seq
MIRT1221538	hsa-miR-4753-5p	CLIP-seq
MIRT1221539	hsa-miR-4760-3p	CLIP-seq
MIRT2590533	hsa-miR-4762-3p	CLIP-seq
MIRT1221540	hsa-miR-4770	CLIP-seq
MIRT2063943	hsa-miR-4786-3p	CLIP-seq
MIRT2590534	hsa-miR-491-5p	CLIP-seq
MIRT1221542	hsa-miR-499-3p	CLIP-seq
MIRT1221543	hsa-miR-499a-3p	CLIP-seq
MIRT1221544	hsa-miR-513c	CLIP-seq
MIRT1221545	hsa-miR-514b-5p	CLIP-seq
MIRT2063945	hsa-miR-522	CLIP-seq
MIRT1221546	hsa-miR-526b	CLIP-seq
MIRT2063946	hsa-miR-541	CLIP-seq
MIRT2590535	hsa-miR-548o	CLIP-seq
MIRT2590536	hsa-miR-561	CLIP-seq
MIRT1221548	hsa-miR-578	CLIP-seq
MIRT2590537	hsa-miR-579	CLIP-seq
MIRT2590538	hsa-miR-583	CLIP-seq
MIRT2063949	hsa-miR-587	CLIP-seq
MIRT1221549	hsa-miR-641	CLIP-seq
MIRT2063951	hsa-miR-654-5p	CLIP-seq
MIRT2590539	hsa-miR-767-5p	CLIP-seq
MIRT2590540	hsa-miR-939	CLIP-seq
MIRT1221493	hsa-miR-105	CLIP-seq
MIRT2063905	hsa-miR-1208	CLIP-seq
MIRT2063906	hsa-miR-1225-3p	CLIP-seq
MIRT2063907	hsa-miR-1233	CLIP-seq
MIRT2063909	hsa-miR-1267	CLIP-seq
MIRT1221495	hsa-miR-1273f	CLIP-seq
MIRT2590514	hsa-miR-129-5p	CLIP-seq
MIRT1221496	hsa-miR-1297	CLIP-seq
MIRT1221497	hsa-miR-1305	CLIP-seq
MIRT2590515	hsa-miR-1323	CLIP-seq
MIRT1221498	hsa-miR-143	CLIP-seq
MIRT2063913	hsa-miR-150	CLIP-seq
MIRT2590516	hsa-miR-186	CLIP-seq
MIRT2063914	hsa-miR-216b	CLIP-seq
MIRT1221509	hsa-miR-26a	CLIP-seq
MIRT1221510	hsa-miR-26b	CLIP-seq
MIRT2590517	hsa-miR-3065-5p	CLIP-seq
MIRT1221511	hsa-miR-3121-5p	CLIP-seq
MIRT2063915	hsa-miR-3123	CLIP-seq
MIRT2590518	hsa-miR-3133	CLIP-seq
MIRT2590519	hsa-miR-3150a-3p	CLIP-seq
MIRT2590520	hsa-miR-3151	CLIP-seq
MIRT2590521	hsa-miR-3163	CLIP-seq
MIRT2590522	hsa-miR-3175	CLIP-seq
MIRT2063917	hsa-miR-3200-5p	CLIP-seq
MIRT2063919	hsa-miR-338-5p	CLIP-seq
MIRT1221513	hsa-miR-34c-3p	CLIP-seq
MIRT2063920	hsa-miR-3529	CLIP-seq
MIRT1221514	hsa-miR-3617	CLIP-seq
MIRT2063921	hsa-miR-3659	CLIP-seq
MIRT2590523	hsa-miR-3662	CLIP-seq
MIRT1221515	hsa-miR-3682-5p	CLIP-seq
MIRT2063922	hsa-miR-370	CLIP-seq
MIRT1221517	hsa-miR-376a	CLIP-seq
MIRT1221518	hsa-miR-376b	CLIP-seq
MIRT2063923	hsa-miR-379	CLIP-seq
MIRT2063924	hsa-miR-3925-5p	CLIP-seq
MIRT2063925	hsa-miR-3940-3p	CLIP-seq
MIRT2063926	hsa-miR-3945	CLIP-seq
MIRT1221520	hsa-miR-4252	CLIP-seq
MIRT2063927	hsa-miR-4253	CLIP-seq
MIRT2590524	hsa-miR-4265	CLIP-seq
MIRT2063928	hsa-miR-4280	CLIP-seq
MIRT2590525	hsa-miR-4296	CLIP-seq
MIRT1221522	hsa-miR-4307	CLIP-seq
MIRT2590526	hsa-miR-4322	CLIP-seq
MIRT1221523	hsa-miR-4420	CLIP-seq
MIRT1221524	hsa-miR-4427	CLIP-seq
MIRT2590527	hsa-miR-4447	CLIP-seq
MIRT2063930	hsa-miR-4451	CLIP-seq
MIRT1221525	hsa-miR-4465	CLIP-seq
MIRT2590528	hsa-miR-4472	CLIP-seq
MIRT2590529	hsa-miR-4474-3p	CLIP-seq
MIRT2063932	hsa-miR-4495	CLIP-seq
MIRT2590530	hsa-miR-4509	CLIP-seq
MIRT2063933	hsa-miR-4527	CLIP-seq
MIRT2590531	hsa-miR-4645-3p	CLIP-seq
MIRT2063934	hsa-miR-4650-3p	CLIP-seq
MIRT2063935	hsa-miR-4658	CLIP-seq
MIRT2063936	hsa-miR-4668-3p	CLIP-seq
MIRT1221531	hsa-miR-4680-3p	CLIP-seq
MIRT2063937	hsa-miR-4682	CLIP-seq
MIRT2063938	hsa-miR-4684-3p	CLIP-seq
MIRT1221533	hsa-miR-4698	CLIP-seq
MIRT1221535	hsa-miR-4708-5p	CLIP-seq
MIRT2063939	hsa-miR-4716-5p	CLIP-seq
MIRT1221537	hsa-miR-4717-5p	CLIP-seq
MIRT2063940	hsa-miR-4718	CLIP-seq
MIRT2063941	hsa-miR-4732-5p	CLIP-seq
MIRT2590532	hsa-miR-4744	CLIP-seq
MIRT1221538	hsa-miR-4753-5p	CLIP-seq
MIRT1221539	hsa-miR-4760-3p	CLIP-seq
MIRT2590533	hsa-miR-4762-3p	CLIP-seq
MIRT1221540	hsa-miR-4770	CLIP-seq
MIRT2063943	hsa-miR-4786-3p	CLIP-seq
MIRT2063944	hsa-miR-490-3p	CLIP-seq
MIRT2590534	hsa-miR-491-5p	CLIP-seq
MIRT1221544	hsa-miR-513c	CLIP-seq
MIRT1221545	hsa-miR-514b-5p	CLIP-seq
MIRT2063945	hsa-miR-522	CLIP-seq
MIRT1221546	hsa-miR-526b	CLIP-seq
MIRT2063946	hsa-miR-541	CLIP-seq
MIRT2590535	hsa-miR-548o	CLIP-seq
MIRT2590536	hsa-miR-561	CLIP-seq
MIRT2063948	hsa-miR-574-5p	CLIP-seq
MIRT1221548	hsa-miR-578	CLIP-seq
MIRT2590537	hsa-miR-579	CLIP-seq
MIRT2590538	hsa-miR-583	CLIP-seq
MIRT2063949	hsa-miR-587	CLIP-seq
MIRT1221549	hsa-miR-641	CLIP-seq
MIRT2063950	hsa-miR-649	CLIP-seq
MIRT2063951	hsa-miR-654-5p	CLIP-seq
MIRT2590539	hsa-miR-767-5p	CLIP-seq
MIRT2590540	hsa-miR-939	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
YY1	Repression	1330541

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003756	Function	Protein disulfide isomerase activity	IEA
GO:0003756	Function	Protein disulfide isomerase activity	TAS	7590364
GO:0005515	Function	Protein binding	IPI	15466936, 21057456, 21670307, 24189400, 30021884, 32296183, 32814053, 33961781
GO:0005615	Component	Extracellular space	IDA	19995400
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005783	Component	Endoplasmic reticulum	TAS	16130169
GO:0005788	Component	Endoplasmic reticulum lumen	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	15308636
GO:0005886	Component	Plasma membrane	IEA
GO:0005929	Component	Cilium	IDA
GO:0006457	Process	Protein folding	TAS	7590364
GO:0015035	Function	Protein-disulfide reductase activity	IBA
GO:0015035	Function	Protein-disulfide reductase activity	IDA	16677074
GO:0016020	Component	Membrane	IEA
GO:0016853	Function	Isomerase activity	IEA
GO:0034451	Component	Centriolar satellite	IDA
GO:0034663	Component	Endoplasmic reticulum chaperone complex	ISS
GO:0034976	Process	Response to endoplasmic reticulum stress	IBA
GO:0036064	Component	Ciliary basal body	IDA
GO:0042470	Component	Melanosome	IEA
GO:0070062	Component	Extracellular exosome	HDA	20458337

MIM	HGNC	e!Ensembl
611099	30168	ENSG00000143870

Q15084

Protein name

Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)

Protein function

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed

PDB

1X5D , 3VWW , 3W8J , 4EF0 , 4GWR , 8CPQ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00085	Thioredoxin	26 → 129	Thioredoxin	Domain
PF00085	Thioredoxin	161 → 267	Thioredoxin	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in platelets (at protein level). {ECO:0000269|PubMed:15466936}.

Sequence

MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
VEDDIDLSDVELDDLGKDEL

Sequence length

440

Interactions

View interactions

	KEGG		Reactome
	Protein processing in endoplasmic reticulum		XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
PERIPHERAL ARTERIAL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (32)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	29725981	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	31230729	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	27760590		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	17420453		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	33761940	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	25225353, 37457742	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	27760590		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	34781823	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34120619	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Permanent Neonatal	Neonatal diabetes mellitus	Pubtator	35856135	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Breast Carcinoma	Breast Carcinoma	BEFREE	26125904		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Carcinoma	Ductal Carcinoma	BEFREE	26125904		★★★★★ ★☆☆☆☆ Found in Text Mining only
Giant Cell Tumor of Bone	Giant cell tumor of bone	BEFREE	28866093		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	27540907		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	27540907		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	BEFREE	22167753		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	22167753	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington Disease	BEFREE	25480889		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	22215138	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver cirrhosis	Pubtator	35856135	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	17420453		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	27760590		★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	Pubtator	35856135	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	18202175	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	19008459, 26125904		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	25480889	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30922965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	35579911	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Diseases	Polycystic kidney disease	Pubtator	35856135	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	31374203		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	33761940	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lung	Lung carcinoma	BEFREE	30922965		★★★★★ ★☆☆☆☆ Found in Text Mining only

PDIA6 (protein disulfide isomerase family A member 6)