Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10120
Gene name	Actin related protein 1B
Gene symbol	ACTR1B
Synonyms (NCBI Gene)	ARP1BCTRN2PC3
Chromosome	2
Chromosome location	2q11.2
Summary	This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, inc

342

Show/Hide all (342)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026412	hsa-miR-192-5p	Microarray	19074876
MIRT048557	hsa-miR-100-5p	CLASH	23622248
MIRT044201	hsa-miR-99b-5p	CLASH	23622248
MIRT764387	hsa-miR-1205	CLIP-seq
MIRT764388	hsa-miR-1224-3p	CLIP-seq
MIRT764389	hsa-miR-1227	CLIP-seq
MIRT764390	hsa-miR-1255a	CLIP-seq
MIRT764391	hsa-miR-1255b	CLIP-seq
MIRT764392	hsa-miR-1260	CLIP-seq
MIRT764393	hsa-miR-1260b	CLIP-seq
MIRT764394	hsa-miR-1272	CLIP-seq
MIRT764395	hsa-miR-1280	CLIP-seq
MIRT764396	hsa-miR-1321	CLIP-seq
MIRT764397	hsa-miR-1470	CLIP-seq
MIRT764398	hsa-miR-150	CLIP-seq
MIRT764399	hsa-miR-188-3p	CLIP-seq
MIRT764400	hsa-miR-1909	CLIP-seq
MIRT764401	hsa-miR-1912	CLIP-seq
MIRT764402	hsa-miR-1915	CLIP-seq
MIRT764403	hsa-miR-3120-5p	CLIP-seq
MIRT764404	hsa-miR-3127-5p	CLIP-seq
MIRT764405	hsa-miR-3130-5p	CLIP-seq
MIRT764406	hsa-miR-3156-3p	CLIP-seq
MIRT764407	hsa-miR-329	CLIP-seq
MIRT764408	hsa-miR-362-3p	CLIP-seq
MIRT764409	hsa-miR-3646	CLIP-seq
MIRT764410	hsa-miR-3681	CLIP-seq
MIRT764411	hsa-miR-3691-5p	CLIP-seq
MIRT764412	hsa-miR-3918	CLIP-seq
MIRT764413	hsa-miR-4266	CLIP-seq
MIRT764414	hsa-miR-4269	CLIP-seq
MIRT764415	hsa-miR-4290	CLIP-seq
MIRT764416	hsa-miR-4300	CLIP-seq
MIRT764417	hsa-miR-4419a	CLIP-seq
MIRT764418	hsa-miR-4451	CLIP-seq
MIRT764419	hsa-miR-4469	CLIP-seq
MIRT764420	hsa-miR-4477a	CLIP-seq
MIRT764421	hsa-miR-4482	CLIP-seq
MIRT764422	hsa-miR-4484	CLIP-seq
MIRT764423	hsa-miR-4510	CLIP-seq
MIRT764424	hsa-miR-4514	CLIP-seq
MIRT764425	hsa-miR-4662a-3p	CLIP-seq
MIRT764426	hsa-miR-4667-3p	CLIP-seq
MIRT764427	hsa-miR-4685-5p	CLIP-seq
MIRT764428	hsa-miR-4690-3p	CLIP-seq
MIRT764429	hsa-miR-4692	CLIP-seq
MIRT764430	hsa-miR-4695-5p	CLIP-seq
MIRT764431	hsa-miR-4713-5p	CLIP-seq
MIRT764432	hsa-miR-4715-3p	CLIP-seq
MIRT764433	hsa-miR-4733-3p	CLIP-seq
MIRT764434	hsa-miR-4739	CLIP-seq
MIRT764435	hsa-miR-4742-5p	CLIP-seq
MIRT764436	hsa-miR-4756-5p	CLIP-seq
MIRT764437	hsa-miR-4761-3p	CLIP-seq
MIRT764438	hsa-miR-4779	CLIP-seq
MIRT764439	hsa-miR-4797-5p	CLIP-seq
MIRT764440	hsa-miR-510	CLIP-seq
MIRT764441	hsa-miR-512-5p	CLIP-seq
MIRT764442	hsa-miR-520d-5p	CLIP-seq
MIRT764443	hsa-miR-524-5p	CLIP-seq
MIRT764444	hsa-miR-532-3p	CLIP-seq
MIRT764445	hsa-miR-548an	CLIP-seq
MIRT764446	hsa-miR-558	CLIP-seq
MIRT764447	hsa-miR-561	CLIP-seq
MIRT764448	hsa-miR-574-5p	CLIP-seq
MIRT764449	hsa-miR-642b	CLIP-seq
MIRT764450	hsa-miR-759	CLIP-seq
MIRT764451	hsa-miR-760	CLIP-seq
MIRT764452	hsa-miR-765	CLIP-seq
MIRT764453	hsa-miR-920	CLIP-seq
MIRT1925220	hsa-miR-10a	CLIP-seq
MIRT1925221	hsa-miR-10b	CLIP-seq
MIRT764394	hsa-miR-1272	CLIP-seq
MIRT764397	hsa-miR-1470	CLIP-seq
MIRT764398	hsa-miR-150	CLIP-seq
MIRT1925222	hsa-miR-339-5p	CLIP-seq
MIRT1925223	hsa-miR-3620	CLIP-seq
MIRT764409	hsa-miR-3646	CLIP-seq
MIRT1925224	hsa-miR-3688-5p	CLIP-seq
MIRT1925225	hsa-miR-3689d	CLIP-seq
MIRT1925226	hsa-miR-4459	CLIP-seq
MIRT764419	hsa-miR-4469	CLIP-seq
MIRT764420	hsa-miR-4477a	CLIP-seq
MIRT764426	hsa-miR-4667-3p	CLIP-seq
MIRT1925227	hsa-miR-4675	CLIP-seq
MIRT764431	hsa-miR-4713-5p	CLIP-seq
MIRT1925228	hsa-miR-4741	CLIP-seq
MIRT764444	hsa-miR-532-3p	CLIP-seq
MIRT2166743	hsa-miR-1301	CLIP-seq
MIRT764397	hsa-miR-1470	CLIP-seq
MIRT764398	hsa-miR-150	CLIP-seq
MIRT764401	hsa-miR-1912	CLIP-seq
MIRT764402	hsa-miR-1915	CLIP-seq
MIRT764404	hsa-miR-3127-5p	CLIP-seq
MIRT764405	hsa-miR-3130-5p	CLIP-seq
MIRT764412	hsa-miR-3918	CLIP-seq
MIRT2166744	hsa-miR-3922-5p	CLIP-seq
MIRT2166745	hsa-miR-4253	CLIP-seq
MIRT764413	hsa-miR-4266	CLIP-seq
MIRT2166746	hsa-miR-4267	CLIP-seq
MIRT2166747	hsa-miR-4421	CLIP-seq
MIRT764419	hsa-miR-4469	CLIP-seq
MIRT764421	hsa-miR-4482	CLIP-seq
MIRT2166748	hsa-miR-4645-5p	CLIP-seq
MIRT2166749	hsa-miR-4660	CLIP-seq
MIRT764425	hsa-miR-4662a-3p	CLIP-seq
MIRT764426	hsa-miR-4667-3p	CLIP-seq
MIRT2166750	hsa-miR-4673	CLIP-seq
MIRT764427	hsa-miR-4685-5p	CLIP-seq
MIRT764428	hsa-miR-4690-3p	CLIP-seq
MIRT764430	hsa-miR-4695-5p	CLIP-seq
MIRT764431	hsa-miR-4713-5p	CLIP-seq
MIRT764433	hsa-miR-4733-3p	CLIP-seq
MIRT764437	hsa-miR-4761-3p	CLIP-seq
MIRT764438	hsa-miR-4779	CLIP-seq
MIRT764439	hsa-miR-4797-5p	CLIP-seq
MIRT2166751	hsa-miR-488	CLIP-seq
MIRT2166752	hsa-miR-5047	CLIP-seq
MIRT764440	hsa-miR-510	CLIP-seq
MIRT764441	hsa-miR-512-5p	CLIP-seq
MIRT764444	hsa-miR-532-3p	CLIP-seq
MIRT764448	hsa-miR-574-5p	CLIP-seq
MIRT764450	hsa-miR-759	CLIP-seq
MIRT2166753	hsa-miR-944	CLIP-seq
MIRT2383857	hsa-miR-1913	CLIP-seq
MIRT2383858	hsa-miR-3064-5p	CLIP-seq
MIRT2383859	hsa-miR-324-3p	CLIP-seq
MIRT764407	hsa-miR-329	CLIP-seq
MIRT764408	hsa-miR-362-3p	CLIP-seq
MIRT764416	hsa-miR-4300	CLIP-seq
MIRT2383860	hsa-miR-4749-3p	CLIP-seq
MIRT764446	hsa-miR-558	CLIP-seq
MIRT2383861	hsa-miR-604	CLIP-seq
MIRT2383862	hsa-miR-647	CLIP-seq
MIRT764453	hsa-miR-920	CLIP-seq
MIRT1925220	hsa-miR-10a	CLIP-seq
MIRT1925221	hsa-miR-10b	CLIP-seq
MIRT764387	hsa-miR-1205	CLIP-seq
MIRT764388	hsa-miR-1224-3p	CLIP-seq
MIRT2469189	hsa-miR-125a-5p	CLIP-seq
MIRT2469190	hsa-miR-125b	CLIP-seq
MIRT764392	hsa-miR-1260	CLIP-seq
MIRT764393	hsa-miR-1260b	CLIP-seq
MIRT2469191	hsa-miR-1266	CLIP-seq
MIRT764394	hsa-miR-1272	CLIP-seq
MIRT764395	hsa-miR-1280	CLIP-seq
MIRT2469192	hsa-miR-1291	CLIP-seq
MIRT2166743	hsa-miR-1301	CLIP-seq
MIRT764396	hsa-miR-1321	CLIP-seq
MIRT2469193	hsa-miR-140-3p	CLIP-seq
MIRT2469194	hsa-miR-147	CLIP-seq
MIRT2469195	hsa-miR-1587	CLIP-seq
MIRT2469196	hsa-miR-1827	CLIP-seq
MIRT764399	hsa-miR-188-3p	CLIP-seq
MIRT764400	hsa-miR-1909	CLIP-seq
MIRT764401	hsa-miR-1912	CLIP-seq
MIRT2383857	hsa-miR-1913	CLIP-seq
MIRT2469197	hsa-miR-1914	CLIP-seq
MIRT2383858	hsa-miR-3064-5p	CLIP-seq
MIRT2469198	hsa-miR-3130-3p	CLIP-seq
MIRT764405	hsa-miR-3130-5p	CLIP-seq
MIRT764406	hsa-miR-3156-3p	CLIP-seq
MIRT2469199	hsa-miR-3173-5p	CLIP-seq
MIRT2469200	hsa-miR-3176	CLIP-seq
MIRT2383859	hsa-miR-324-3p	CLIP-seq
MIRT2469201	hsa-miR-328	CLIP-seq
MIRT764407	hsa-miR-329	CLIP-seq
MIRT1925222	hsa-miR-339-5p	CLIP-seq
MIRT2469202	hsa-miR-3612	CLIP-seq
MIRT1925223	hsa-miR-3620	CLIP-seq
MIRT764408	hsa-miR-362-3p	CLIP-seq
MIRT2469203	hsa-miR-3670	CLIP-seq
MIRT2469204	hsa-miR-378g	CLIP-seq
MIRT2469205	hsa-miR-3922-3p	CLIP-seq
MIRT2166744	hsa-miR-3922-5p	CLIP-seq
MIRT2469206	hsa-miR-4254	CLIP-seq
MIRT764413	hsa-miR-4266	CLIP-seq
MIRT2166746	hsa-miR-4267	CLIP-seq
MIRT2469207	hsa-miR-4270	CLIP-seq
MIRT2469208	hsa-miR-4271	CLIP-seq
MIRT2469209	hsa-miR-4292	CLIP-seq
MIRT764416	hsa-miR-4300	CLIP-seq
MIRT2469210	hsa-miR-4308	CLIP-seq
MIRT2469211	hsa-miR-4319	CLIP-seq
MIRT2469212	hsa-miR-4324	CLIP-seq
MIRT2166747	hsa-miR-4421	CLIP-seq
MIRT2469213	hsa-miR-4441	CLIP-seq
MIRT2469214	hsa-miR-4450	CLIP-seq
MIRT764421	hsa-miR-4482	CLIP-seq
MIRT2469215	hsa-miR-4492	CLIP-seq
MIRT2469216	hsa-miR-4498	CLIP-seq
MIRT2469217	hsa-miR-4518	CLIP-seq
MIRT2469218	hsa-miR-4633-3p	CLIP-seq
MIRT2469219	hsa-miR-4640-3p	CLIP-seq
MIRT2166748	hsa-miR-4645-5p	CLIP-seq
MIRT2469220	hsa-miR-4650-5p	CLIP-seq
MIRT2469221	hsa-miR-4656	CLIP-seq
MIRT2166749	hsa-miR-4660	CLIP-seq
MIRT764425	hsa-miR-4662a-3p	CLIP-seq
MIRT2469222	hsa-miR-4667-5p	CLIP-seq
MIRT2166750	hsa-miR-4673	CLIP-seq
MIRT1925227	hsa-miR-4675	CLIP-seq
MIRT764427	hsa-miR-4685-5p	CLIP-seq
MIRT764428	hsa-miR-4690-3p	CLIP-seq
MIRT2469223	hsa-miR-4693-3p	CLIP-seq
MIRT764430	hsa-miR-4695-5p	CLIP-seq
MIRT2469224	hsa-miR-4700-5p	CLIP-seq
MIRT2469225	hsa-miR-4722-3p	CLIP-seq
MIRT2469226	hsa-miR-4725-3p	CLIP-seq
MIRT2469227	hsa-miR-4725-5p	CLIP-seq
MIRT2469228	hsa-miR-4731-5p	CLIP-seq
MIRT2469229	hsa-miR-4732-5p	CLIP-seq
MIRT764433	hsa-miR-4733-3p	CLIP-seq
MIRT764434	hsa-miR-4739	CLIP-seq
MIRT1925228	hsa-miR-4741	CLIP-seq
MIRT2469230	hsa-miR-4747-5p	CLIP-seq
MIRT2383860	hsa-miR-4749-3p	CLIP-seq
MIRT2469231	hsa-miR-4755-3p	CLIP-seq
MIRT764436	hsa-miR-4756-5p	CLIP-seq
MIRT764437	hsa-miR-4761-3p	CLIP-seq
MIRT764438	hsa-miR-4779	CLIP-seq
MIRT2469232	hsa-miR-4785	CLIP-seq
MIRT2469233	hsa-miR-4794	CLIP-seq
MIRT764439	hsa-miR-4797-5p	CLIP-seq
MIRT2166751	hsa-miR-488	CLIP-seq
MIRT2469234	hsa-miR-504	CLIP-seq
MIRT2166752	hsa-miR-5047	CLIP-seq
MIRT764440	hsa-miR-510	CLIP-seq
MIRT764441	hsa-miR-512-5p	CLIP-seq
MIRT764446	hsa-miR-558	CLIP-seq
MIRT764448	hsa-miR-574-5p	CLIP-seq
MIRT2469235	hsa-miR-581	CLIP-seq
MIRT2469236	hsa-miR-592	CLIP-seq
MIRT2469237	hsa-miR-597	CLIP-seq
MIRT2383861	hsa-miR-604	CLIP-seq
MIRT764449	hsa-miR-642b	CLIP-seq
MIRT2383862	hsa-miR-647	CLIP-seq
MIRT2469238	hsa-miR-650	CLIP-seq
MIRT2469239	hsa-miR-652	CLIP-seq
MIRT2469240	hsa-miR-7	CLIP-seq
MIRT764450	hsa-miR-759	CLIP-seq
MIRT2469241	hsa-miR-762	CLIP-seq
MIRT2469242	hsa-miR-892b	CLIP-seq
MIRT764453	hsa-miR-920	CLIP-seq
MIRT764388	hsa-miR-1224-3p	CLIP-seq
MIRT2469189	hsa-miR-125a-5p	CLIP-seq
MIRT2469190	hsa-miR-125b	CLIP-seq
MIRT764392	hsa-miR-1260	CLIP-seq
MIRT764393	hsa-miR-1260b	CLIP-seq
MIRT2469191	hsa-miR-1266	CLIP-seq
MIRT764394	hsa-miR-1272	CLIP-seq
MIRT764395	hsa-miR-1280	CLIP-seq
MIRT2469192	hsa-miR-1291	CLIP-seq
MIRT2166743	hsa-miR-1301	CLIP-seq
MIRT764396	hsa-miR-1321	CLIP-seq
MIRT2469194	hsa-miR-147	CLIP-seq
MIRT2469195	hsa-miR-1587	CLIP-seq
MIRT2469196	hsa-miR-1827	CLIP-seq
MIRT764399	hsa-miR-188-3p	CLIP-seq
MIRT764401	hsa-miR-1912	CLIP-seq
MIRT2383857	hsa-miR-1913	CLIP-seq
MIRT2469197	hsa-miR-1914	CLIP-seq
MIRT2383858	hsa-miR-3064-5p	CLIP-seq
MIRT2469198	hsa-miR-3130-3p	CLIP-seq
MIRT764405	hsa-miR-3130-5p	CLIP-seq
MIRT764406	hsa-miR-3156-3p	CLIP-seq
MIRT2469200	hsa-miR-3176	CLIP-seq
MIRT2383859	hsa-miR-324-3p	CLIP-seq
MIRT2469201	hsa-miR-328	CLIP-seq
MIRT764407	hsa-miR-329	CLIP-seq
MIRT2469202	hsa-miR-3612	CLIP-seq
MIRT764408	hsa-miR-362-3p	CLIP-seq
MIRT2469203	hsa-miR-3670	CLIP-seq
MIRT2469204	hsa-miR-378g	CLIP-seq
MIRT2469205	hsa-miR-3922-3p	CLIP-seq
MIRT2166744	hsa-miR-3922-5p	CLIP-seq
MIRT2469206	hsa-miR-4254	CLIP-seq
MIRT764413	hsa-miR-4266	CLIP-seq
MIRT2166746	hsa-miR-4267	CLIP-seq
MIRT2469207	hsa-miR-4270	CLIP-seq
MIRT2469208	hsa-miR-4271	CLIP-seq
MIRT2469209	hsa-miR-4292	CLIP-seq
MIRT764416	hsa-miR-4300	CLIP-seq
MIRT2469210	hsa-miR-4308	CLIP-seq
MIRT2469211	hsa-miR-4319	CLIP-seq
MIRT2469212	hsa-miR-4324	CLIP-seq
MIRT2166747	hsa-miR-4421	CLIP-seq
MIRT2469213	hsa-miR-4441	CLIP-seq
MIRT2469214	hsa-miR-4450	CLIP-seq
MIRT764421	hsa-miR-4482	CLIP-seq
MIRT2469215	hsa-miR-4492	CLIP-seq
MIRT2469216	hsa-miR-4498	CLIP-seq
MIRT2469217	hsa-miR-4518	CLIP-seq
MIRT2469218	hsa-miR-4633-3p	CLIP-seq
MIRT2469219	hsa-miR-4640-3p	CLIP-seq
MIRT2166748	hsa-miR-4645-5p	CLIP-seq
MIRT2469221	hsa-miR-4656	CLIP-seq
MIRT2166749	hsa-miR-4660	CLIP-seq
MIRT764425	hsa-miR-4662a-3p	CLIP-seq
MIRT2469222	hsa-miR-4667-5p	CLIP-seq
MIRT2166750	hsa-miR-4673	CLIP-seq
MIRT1925227	hsa-miR-4675	CLIP-seq
MIRT764427	hsa-miR-4685-5p	CLIP-seq
MIRT764428	hsa-miR-4690-3p	CLIP-seq
MIRT2469223	hsa-miR-4693-3p	CLIP-seq
MIRT764430	hsa-miR-4695-5p	CLIP-seq
MIRT2469224	hsa-miR-4700-5p	CLIP-seq
MIRT2469226	hsa-miR-4725-3p	CLIP-seq
MIRT2469227	hsa-miR-4725-5p	CLIP-seq
MIRT2469228	hsa-miR-4731-5p	CLIP-seq
MIRT2469229	hsa-miR-4732-5p	CLIP-seq
MIRT764433	hsa-miR-4733-3p	CLIP-seq
MIRT764434	hsa-miR-4739	CLIP-seq
MIRT1925228	hsa-miR-4741	CLIP-seq
MIRT2469230	hsa-miR-4747-5p	CLIP-seq
MIRT2383860	hsa-miR-4749-3p	CLIP-seq
MIRT764436	hsa-miR-4756-5p	CLIP-seq
MIRT764437	hsa-miR-4761-3p	CLIP-seq
MIRT764438	hsa-miR-4779	CLIP-seq
MIRT2469232	hsa-miR-4785	CLIP-seq
MIRT2469233	hsa-miR-4794	CLIP-seq
MIRT764439	hsa-miR-4797-5p	CLIP-seq
MIRT2166751	hsa-miR-488	CLIP-seq
MIRT2469234	hsa-miR-504	CLIP-seq
MIRT2166752	hsa-miR-5047	CLIP-seq
MIRT764440	hsa-miR-510	CLIP-seq
MIRT764441	hsa-miR-512-5p	CLIP-seq
MIRT764446	hsa-miR-558	CLIP-seq
MIRT764448	hsa-miR-574-5p	CLIP-seq
MIRT2469235	hsa-miR-581	CLIP-seq
MIRT2469236	hsa-miR-592	CLIP-seq
MIRT2469237	hsa-miR-597	CLIP-seq
MIRT2383861	hsa-miR-604	CLIP-seq
MIRT764449	hsa-miR-642b	CLIP-seq
MIRT2383862	hsa-miR-647	CLIP-seq
MIRT2469238	hsa-miR-650	CLIP-seq
MIRT2469239	hsa-miR-652	CLIP-seq
MIRT2469240	hsa-miR-7	CLIP-seq
MIRT764450	hsa-miR-759	CLIP-seq
MIRT2469241	hsa-miR-762	CLIP-seq
MIRT2469242	hsa-miR-892b	CLIP-seq
MIRT764453	hsa-miR-920	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005515	Function	Protein binding	IPI	12857853, 26638075, 32814053, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005813	Component	Centrosome	IEA
GO:0005815	Component	Microtubule organizing center	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005869	Component	Dynactin complex	IBA
GO:0005869	Component	Dynactin complex	TAS	7696711
GO:0016020	Component	Membrane	HDA	19946888
GO:0034774	Component	Secretory granule lumen	TAS
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
605144	168	ENSG00000115073

P42025

Protein name

Beta-centractin (Actin-related protein 1B) (ARP1B)

Protein function

Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00022	Actin	7 → 376	Actin	Family

Sequence

MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP
KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN
REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI
MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ
YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL
SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK
KEYEEDGSRAIHRKTF

Sequence length

376

Interactions

View interactions

	KEGG		Reactome
	Motor proteins Amyotrophic lateral sclerosis Huntington disease Pathways of neurodegeneration - multiple diseases Salmonella infection		MHC class II antigen presentation Neutrophil degranulation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (18)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Duane retraction syndrome	Uncertain significance	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Gastric cancer	Uncertain significance; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of large intestine	Colorectal Cancer	GWASCAT_DG	31089142	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	15741235	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	GWASCAT_DG	31089142	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	GWASCAT_DG	31089142	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	17619203	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	15741235	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of large intestine	Colorectal Neoplasms	GWASCAT_DG	31089142	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	25284287	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	GWASCAT_DG	31089142	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29432691	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	15741235	★★★★★ ★☆☆☆☆ Found in Text Mining only

ACTR1B (actin related protein 1B)