FEM1B (fem-1 homolog B)

Gene

• Entrez ID: 10116
• Gene name: Fem-1 homolog B
• Gene symbol: FEM1B
• Synonyms (NCBI Gene): F1A-ALPHA, F1AA, FEM1-beta, NEDBES
• Chromosome: 15
• Chromosome location: 15q23
• Summary: This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pa

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT047848	hsa-miR-30c-5p	CLASH	23622248
MIRT047779	hsa-miR-30d-5p	CLASH	23622248
MIRT047584	hsa-miR-10a-5p	CLASH	23622248
MIRT047427	hsa-miR-10b-5p	CLASH	23622248
MIRT046117	hsa-miR-30b-5p	CLASH	23622248
MIRT044948	hsa-miR-186-5p	CLASH	23622248
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT641241	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT641240	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT641239	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT507310	hsa-miR-646	PAR-CLIP	20371350
MIRT507309	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT567581	hsa-miR-26b-3p	PAR-CLIP	20371350
MIRT567580	hsa-miR-4326	PAR-CLIP	20371350
MIRT567579	hsa-miR-6083	PAR-CLIP	20371350
MIRT557897	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT557896	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT557895	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT557894	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT557893	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT557892	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT557891	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT557890	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT557889	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT557888	hsa-miR-6507-3p	PAR-CLIP	20371350
MIRT557887	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT557886	hsa-miR-224-3p	PAR-CLIP	20371350
MIRT557885	hsa-miR-522-3p	PAR-CLIP	20371350
MIRT557884	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT557883	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT557882	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT557881	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT557880	hsa-miR-499a-3p	PAR-CLIP	20371350
MIRT557879	hsa-miR-499b-3p	PAR-CLIP	20371350
MIRT557878	hsa-miR-4307	PAR-CLIP	20371350
MIRT557877	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT557876	hsa-miR-5087	PAR-CLIP	20371350
MIRT557875	hsa-miR-4477a	PAR-CLIP	20371350
MIRT557874	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT557873	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT557897	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT557896	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT557895	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT557894	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT557893	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT557892	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT557891	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT557890	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT557889	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT557888	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT557887	hsa-miR-4694-3p	PAR-CLIP	21572407
MIRT557886	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT557885	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT557884	hsa-miR-224-5p	PAR-CLIP	21572407
MIRT557883	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT557882	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT557881	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT557880	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT557879	hsa-miR-499b-3p	PAR-CLIP	21572407
MIRT557878	hsa-miR-4307	PAR-CLIP	21572407
MIRT557877	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT557876	hsa-miR-5087	PAR-CLIP	21572407
MIRT557875	hsa-miR-4477a	PAR-CLIP	21572407
MIRT557874	hsa-miR-514a-3p	PAR-CLIP	21572407
MIRT557873	hsa-miR-514b-3p	PAR-CLIP	21572407
MIRT548239	hsa-miR-29c-3p	PAR-CLIP	21572407
MIRT548238	hsa-miR-29a-3p	PAR-CLIP	21572407
MIRT548237	hsa-miR-29b-3p	PAR-CLIP	21572407
MIRT507311	hsa-miR-5003-3p	PAR-CLIP	21572407
MIRT548236	hsa-miR-6871-3p	PAR-CLIP	21572407
MIRT548235	hsa-miR-585-5p	PAR-CLIP	21572407
MIRT548234	hsa-miR-5682	PAR-CLIP	21572407
MIRT548233	hsa-miR-374b-3p	PAR-CLIP	21572407
MIRT507311	hsa-miR-5003-3p	PAR-CLIP	23446348
MIRT507310	hsa-miR-646	PAR-CLIP	23446348
MIRT507309	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT507308	hsa-miR-5692a	PAR-CLIP	23446348
MIRT507307	hsa-miR-3121-3p	PAR-CLIP	23446348
MIRT507306	hsa-miR-4519	PAR-CLIP	23446348
MIRT507305	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT507304	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT507303	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT507302	hsa-miR-6733-3p	PAR-CLIP	23446348
MIRT507301	hsa-miR-1250-3p	PAR-CLIP	23446348
MIRT507300	hsa-miR-153-5p	PAR-CLIP	23446348
MIRT507299	hsa-miR-939-3p	PAR-CLIP	23446348
MIRT507298	hsa-miR-6852-5p	PAR-CLIP	23446348
MIRT507297	hsa-miR-6742-3p	PAR-CLIP	23446348
MIRT507296	hsa-miR-6758-3p	PAR-CLIP	23446348
MIRT507295	hsa-miR-6861-5p	PAR-CLIP	23446348
MIRT507294	hsa-miR-7152-3p	PAR-CLIP	23446348
MIRT507293	hsa-miR-302a-5p	PAR-CLIP	23446348
MIRT507292	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT507291	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507290	hsa-miR-6131	PAR-CLIP	23446348
MIRT507289	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT507288	hsa-miR-197-5p	PAR-CLIP	23446348
MIRT507287	hsa-miR-3132	PAR-CLIP	23446348
MIRT507286	hsa-miR-200c-5p	PAR-CLIP	23446348
MIRT507285	hsa-miR-550a-3p	PAR-CLIP	23446348
MIRT507284	hsa-miR-4711-3p	PAR-CLIP	23446348
MIRT507283	hsa-miR-4662a-5p	PAR-CLIP	23446348
MIRT507282	hsa-miR-4473	PAR-CLIP	23446348
MIRT507281	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT507280	hsa-miR-1343-3p	PAR-CLIP	23446348
MIRT507279	hsa-miR-6783-3p	PAR-CLIP	23446348
MIRT507278	hsa-miR-1229-5p	PAR-CLIP	23446348
MIRT476877	hsa-miR-3609	PAR-CLIP	23592263
MIRT476878	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT476876	hsa-miR-138-1-3p	PAR-CLIP	23592263
MIRT476874	hsa-miR-3655	PAR-CLIP	23592263
MIRT476875	hsa-miR-3682-5p	PAR-CLIP	23592263
MIRT476873	hsa-miR-6715b-3p	PAR-CLIP	23592263
MIRT476872	hsa-miR-578	PAR-CLIP	23592263
MIRT727660	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT727658	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT641241	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT641240	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT641239	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT616730	hsa-miR-8063	HITS-CLIP	23824327
MIRT616729	hsa-miR-4698	HITS-CLIP	23824327
MIRT616728	hsa-miR-4310	HITS-CLIP	23824327
MIRT616727	hsa-miR-7157-5p	HITS-CLIP	23824327
MIRT616726	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT616725	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT616724	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT616723	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT616722	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT616721	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT616720	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT616719	hsa-miR-4291	HITS-CLIP	23824327
MIRT616718	hsa-miR-623	HITS-CLIP	23824327
MIRT616717	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT616716	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT616715	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT616714	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT616713	hsa-miR-511-5p	HITS-CLIP	23824327
MIRT616712	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT616711	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT507310	hsa-miR-646	PAR-CLIP	20371350
MIRT507309	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT567581	hsa-miR-26b-3p	PAR-CLIP	20371350
MIRT567580	hsa-miR-4326	PAR-CLIP	20371350
MIRT567579	hsa-miR-6083	PAR-CLIP	20371350
MIRT557897	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT557896	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT557895	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT557894	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT557893	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT557892	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT557891	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT557890	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT557889	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT557888	hsa-miR-6507-3p	PAR-CLIP	20371350
MIRT557887	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT557886	hsa-miR-224-3p	PAR-CLIP	20371350
MIRT557885	hsa-miR-522-3p	PAR-CLIP	20371350
MIRT557884	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT557883	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT557882	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT557881	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT557880	hsa-miR-499a-3p	PAR-CLIP	20371350
MIRT557879	hsa-miR-499b-3p	PAR-CLIP	20371350
MIRT557878	hsa-miR-4307	PAR-CLIP	20371350
MIRT557877	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT557876	hsa-miR-5087	PAR-CLIP	20371350
MIRT557875	hsa-miR-4477a	PAR-CLIP	20371350
MIRT557874	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT557873	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT557897	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT557896	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT557895	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT557894	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT557893	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT557892	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT557891	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT557890	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT557889	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT557888	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT557887	hsa-miR-4694-3p	PAR-CLIP	21572407
MIRT557886	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT557885	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT557884	hsa-miR-224-5p	PAR-CLIP	21572407
MIRT557883	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT557882	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT557881	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT557880	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT557879	hsa-miR-499b-3p	PAR-CLIP	21572407
MIRT557878	hsa-miR-4307	PAR-CLIP	21572407
MIRT557877	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT557876	hsa-miR-5087	PAR-CLIP	21572407
MIRT557875	hsa-miR-4477a	PAR-CLIP	21572407
MIRT557874	hsa-miR-514a-3p	PAR-CLIP	21572407
MIRT557873	hsa-miR-514b-3p	PAR-CLIP	21572407
MIRT548239	hsa-miR-29c-3p	PAR-CLIP	21572407
MIRT548238	hsa-miR-29a-3p	PAR-CLIP	21572407
MIRT548237	hsa-miR-29b-3p	PAR-CLIP	21572407
MIRT507311	hsa-miR-5003-3p	PAR-CLIP	21572407
MIRT548236	hsa-miR-6871-3p	PAR-CLIP	21572407
MIRT548235	hsa-miR-585-5p	PAR-CLIP	21572407
MIRT548234	hsa-miR-5682	PAR-CLIP	21572407
MIRT548233	hsa-miR-374b-3p	PAR-CLIP	21572407
MIRT507311	hsa-miR-5003-3p	PAR-CLIP	23446348
MIRT507310	hsa-miR-646	PAR-CLIP	23446348
MIRT507309	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT507308	hsa-miR-5692a	PAR-CLIP	23446348
MIRT507307	hsa-miR-3121-3p	PAR-CLIP	23446348
MIRT507306	hsa-miR-4519	PAR-CLIP	23446348
MIRT507305	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT507304	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT507303	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT507302	hsa-miR-6733-3p	PAR-CLIP	23446348
MIRT507301	hsa-miR-1250-3p	PAR-CLIP	23446348
MIRT507300	hsa-miR-153-5p	PAR-CLIP	23446348
MIRT507299	hsa-miR-939-3p	PAR-CLIP	23446348
MIRT507298	hsa-miR-6852-5p	PAR-CLIP	23446348
MIRT507297	hsa-miR-6742-3p	PAR-CLIP	23446348
MIRT507296	hsa-miR-6758-3p	PAR-CLIP	23446348
MIRT507295	hsa-miR-6861-5p	PAR-CLIP	23446348
MIRT507294	hsa-miR-7152-3p	PAR-CLIP	23446348
MIRT507293	hsa-miR-302a-5p	PAR-CLIP	23446348
MIRT507292	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT507291	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507290	hsa-miR-6131	PAR-CLIP	23446348
MIRT507289	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT507288	hsa-miR-197-5p	PAR-CLIP	23446348
MIRT507287	hsa-miR-3132	PAR-CLIP	23446348
MIRT507286	hsa-miR-200c-5p	PAR-CLIP	23446348
MIRT507285	hsa-miR-550a-3p	PAR-CLIP	23446348
MIRT507284	hsa-miR-4711-3p	PAR-CLIP	23446348
MIRT507283	hsa-miR-4662a-5p	PAR-CLIP	23446348
MIRT507282	hsa-miR-4473	PAR-CLIP	23446348
MIRT507281	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT507280	hsa-miR-1343-3p	PAR-CLIP	23446348
MIRT507279	hsa-miR-6783-3p	PAR-CLIP	23446348
MIRT507278	hsa-miR-1229-5p	PAR-CLIP	23446348
MIRT476877	hsa-miR-3609	PAR-CLIP	23592263
MIRT476878	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT476876	hsa-miR-138-1-3p	PAR-CLIP	23592263
MIRT476874	hsa-miR-3655	PAR-CLIP	23592263
MIRT476875	hsa-miR-3682-5p	PAR-CLIP	23592263
MIRT476873	hsa-miR-6715b-3p	PAR-CLIP	23592263
MIRT476872	hsa-miR-578	PAR-CLIP	23592263
MIRT994626	hsa-miR-29a	CLIP-seq
MIRT994627	hsa-miR-29b	CLIP-seq
MIRT994628	hsa-miR-29c	CLIP-seq
MIRT994629	hsa-miR-4704-3p	CLIP-seq
MIRT994630	hsa-miR-548n	CLIP-seq
MIRT994631	hsa-miR-548t	CLIP-seq
MIRT994626	hsa-miR-29a	CLIP-seq
MIRT994627	hsa-miR-29b	CLIP-seq
MIRT994628	hsa-miR-29c	CLIP-seq
MIRT994630	hsa-miR-548n	CLIP-seq
MIRT994631	hsa-miR-548t	CLIP-seq
MIRT994626	hsa-miR-29a	CLIP-seq
MIRT994627	hsa-miR-29b	CLIP-seq
MIRT994628	hsa-miR-29c	CLIP-seq
MIRT994630	hsa-miR-548n	CLIP-seq
MIRT994631	hsa-miR-548t	CLIP-seq
MIRT994626	hsa-miR-29a	CLIP-seq
MIRT994627	hsa-miR-29b	CLIP-seq
MIRT994628	hsa-miR-29c	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IBA
GO:0002070	Process	Epithelial cell maturation	IEA
GO:0005123	Function	Death receptor binding	IMP	10542291
GO:0005123	Function	Death receptor binding	NAS	10623617
GO:0005515	Function	Protein binding	IPI	11559703, 17003112, 19330022
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	19330022
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	24076122
GO:0005737	Component	Cytoplasm	IDA	19330022
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	NAS	10623617
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0031462	Component	Cul2-RING ubiquitin ligase complex	IDA	29779948
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	24076122
GO:0046872	Function	Metal ion binding	IEA
GO:0051438	Process	Regulation of ubiquitin-protein transferase activity	IMP	15601820
GO:0060442	Process	Branching involved in prostate gland morphogenesis	IEA
GO:0060743	Process	Epithelial cell maturation involved in prostate gland development	IEA
GO:0140627	Process	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	IDA	29779948, 33398168, 33398170
GO:0140627	Process	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	IEA
GO:1902041	Process	Regulation of extrinsic apoptotic signaling pathway via death domain receptors	IMP	10542291
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IBA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IDA	24076122, 29779948, 33398168, 33398170
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IEA
GO:2000001	Process	Regulation of DNA damage checkpoint	IMP	19330022

Other IDs

• MIM: 613539
• HGNC: 3649
• e!Ensembl: ENSG00000169018

Protein

• UniProt ID: Q9UK73
• Protein name: Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)
• Protein function: Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their
• PDB: 6LBF, 7CNG, 7EL6, 8IJ1, 8JE1, 8JE2, 8WQA, 8WQB, 8WQC, 8WQD, 8WQE, 8WQF, 8WQG, 8WQH, 8WQI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	8 → 118	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	115 → 184	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	158 → 248	Ankyrin repeats (3 copies)	Repeat
  PF00023	Ank	483 → 530	Ankyrin repeat	Repeat

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed (PubMed:10542291). Highly expressed in testis (PubMed:10542291). Weakly expressed in other tissues (PubMed:10542291). {ECO:0000269|PubMed:10542291}.
• Sequence:

  MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
  VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
  NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
  NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
  HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIH
  AYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEF
  EQCIKLWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQ
  SMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPR
  TREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIV
  QYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCL
  AARAVRANDINYQDQIPRTLEEFVGFH

• Sequence length: 627

Pathways

Reactome:

Neddylation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COMPLEX NEURODEVELOPMENTAL DISORDER	—	GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	33875655	Associate	★☆☆☆☆ Found in Text Mining only
Bardet-Biedl Syndrome	Bardet-Biedl Syndrome	BEFREE	10768616		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	19855191		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	19855191	Stimulate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	34784930	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	34784930	Associate	★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	18757445	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	31036916		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	31036916	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	36003920	Associate	★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	19855191		★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	31036916		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	18757445		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	LHGDN	18757445		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic ovary syndrome	Pubtator	18757445	Associate	★☆☆☆☆ Found in Text Mining only
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	27644318		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary fibrosis	Pubtator	30756084	Associate	★☆☆☆☆ Found in Text Mining only
Sepsis	Sepsis	Pubtator	39438952	Associate	★☆☆☆☆ Found in Text Mining only