Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10109
Gene name	Actin related protein 2/3 complex subunit 2
Gene symbol	ARPC2
Synonyms (NCBI Gene)	ARC34PNAS-139PRO2446p34-Arc
Chromosome	2
Chromosome location	2q35
Summary	This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by

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Show/Hide all (263)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050988	hsa-miR-17-5p	CLASH	23622248
MIRT050616	hsa-miR-20a-5p	CLASH	23622248
MIRT049237	hsa-miR-92a-3p	CLASH	23622248
MIRT048830	hsa-miR-93-5p	CLASH	23622248
MIRT045659	hsa-miR-149-5p	CLASH	23622248
MIRT045659	hsa-miR-149-5p	CLASH	23622248
MIRT719035	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT719030	hsa-miR-411-5p	HITS-CLIP	19536157
MIRT719034	hsa-miR-6872-3p	HITS-CLIP	19536157
MIRT719032	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT719033	hsa-miR-6832-5p	HITS-CLIP	19536157
MIRT719031	hsa-miR-4775	HITS-CLIP	19536157
MIRT719030	hsa-miR-411-5p	HITS-CLIP	19536157
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT677413	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677412	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677411	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677410	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677409	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677408	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT678598	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT678597	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT678596	hsa-miR-6131	HITS-CLIP	23824327
MIRT677407	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT678595	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT678594	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT677413	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677412	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677411	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677410	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677409	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677408	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677407	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT669469	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669472	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT669471	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT669469	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT660505	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT660504	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT660503	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT660502	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT660501	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT660500	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT660499	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT660498	hsa-miR-1202	HITS-CLIP	23824327
MIRT660497	hsa-miR-3972	HITS-CLIP	23824327
MIRT660496	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT719035	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT719030	hsa-miR-411-5p	HITS-CLIP	19536157
MIRT719034	hsa-miR-6872-3p	HITS-CLIP	19536157
MIRT719032	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT719033	hsa-miR-6832-5p	HITS-CLIP	19536157
MIRT719031	hsa-miR-4775	HITS-CLIP	19536157
MIRT719030	hsa-miR-411-5p	HITS-CLIP	19536157
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT677413	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677412	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677411	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677410	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677409	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677408	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT678598	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT678597	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT678596	hsa-miR-6131	HITS-CLIP	23824327
MIRT677407	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT678595	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT678594	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT677413	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677412	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677411	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677410	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677409	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677408	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677407	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT669469	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT669477	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669476	hsa-miR-764	HITS-CLIP	23824327
MIRT669475	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669474	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669473	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669472	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT669471	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT669470	hsa-miR-640	HITS-CLIP	23824327
MIRT669469	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT660505	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT660504	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT660503	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT660502	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT660501	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT660500	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT660499	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT660498	hsa-miR-1202	HITS-CLIP	23824327
MIRT660497	hsa-miR-3972	HITS-CLIP	23824327
MIRT660496	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT799717	hsa-miR-1184	CLIP-seq
MIRT799718	hsa-miR-1205	CLIP-seq
MIRT799719	hsa-miR-1264	CLIP-seq
MIRT799720	hsa-miR-1292	CLIP-seq
MIRT799721	hsa-miR-2052	CLIP-seq
MIRT799722	hsa-miR-217	CLIP-seq
MIRT799723	hsa-miR-25	CLIP-seq
MIRT799724	hsa-miR-3158-5p	CLIP-seq
MIRT799725	hsa-miR-32	CLIP-seq
MIRT799726	hsa-miR-3545-3p	CLIP-seq
MIRT799727	hsa-miR-363	CLIP-seq
MIRT799728	hsa-miR-367	CLIP-seq
MIRT799729	hsa-miR-3671	CLIP-seq
MIRT799730	hsa-miR-4266	CLIP-seq
MIRT799731	hsa-miR-4433	CLIP-seq
MIRT799732	hsa-miR-4453	CLIP-seq
MIRT799733	hsa-miR-4471	CLIP-seq
MIRT799734	hsa-miR-450b-5p	CLIP-seq
MIRT799735	hsa-miR-4538	CLIP-seq
MIRT799736	hsa-miR-4680-5p	CLIP-seq
MIRT799737	hsa-miR-4700-3p	CLIP-seq
MIRT799738	hsa-miR-4760-5p	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799740	hsa-miR-518a-5p	CLIP-seq
MIRT799741	hsa-miR-527	CLIP-seq
MIRT799742	hsa-miR-544	CLIP-seq
MIRT799743	hsa-miR-570	CLIP-seq
MIRT799744	hsa-miR-635	CLIP-seq
MIRT799745	hsa-miR-888	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq
MIRT799747	hsa-miR-92a	CLIP-seq
MIRT799748	hsa-miR-92b	CLIP-seq
MIRT799723	hsa-miR-25	CLIP-seq
MIRT799749	hsa-miR-3148	CLIP-seq
MIRT799725	hsa-miR-32	CLIP-seq
MIRT799727	hsa-miR-363	CLIP-seq
MIRT799728	hsa-miR-367	CLIP-seq
MIRT799750	hsa-miR-3978	CLIP-seq
MIRT799732	hsa-miR-4453	CLIP-seq
MIRT799751	hsa-miR-4477a	CLIP-seq
MIRT799735	hsa-miR-4538	CLIP-seq
MIRT799738	hsa-miR-4760-5p	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799740	hsa-miR-518a-5p	CLIP-seq
MIRT799741	hsa-miR-527	CLIP-seq
MIRT799752	hsa-miR-583	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq
MIRT799747	hsa-miR-92a	CLIP-seq
MIRT799748	hsa-miR-92b	CLIP-seq
MIRT799719	hsa-miR-1264	CLIP-seq
MIRT799717	hsa-miR-1184	CLIP-seq
MIRT799718	hsa-miR-1205	CLIP-seq
MIRT799719	hsa-miR-1264	CLIP-seq
MIRT1936255	hsa-miR-188-5p	CLIP-seq
MIRT799721	hsa-miR-2052	CLIP-seq
MIRT799723	hsa-miR-25	CLIP-seq
MIRT799749	hsa-miR-3148	CLIP-seq
MIRT799724	hsa-miR-3158-5p	CLIP-seq
MIRT1936256	hsa-miR-3177-5p	CLIP-seq
MIRT799725	hsa-miR-32	CLIP-seq
MIRT799726	hsa-miR-3545-3p	CLIP-seq
MIRT799727	hsa-miR-363	CLIP-seq
MIRT1936257	hsa-miR-3653	CLIP-seq
MIRT1936258	hsa-miR-3658	CLIP-seq
MIRT799728	hsa-miR-367	CLIP-seq
MIRT799729	hsa-miR-3671	CLIP-seq
MIRT799750	hsa-miR-3978	CLIP-seq
MIRT799730	hsa-miR-4266	CLIP-seq
MIRT799731	hsa-miR-4433	CLIP-seq
MIRT799732	hsa-miR-4453	CLIP-seq
MIRT799734	hsa-miR-450b-5p	CLIP-seq
MIRT1936259	hsa-miR-4511	CLIP-seq
MIRT799735	hsa-miR-4538	CLIP-seq
MIRT799736	hsa-miR-4680-5p	CLIP-seq
MIRT1936260	hsa-miR-4694-3p	CLIP-seq
MIRT1936261	hsa-miR-4698	CLIP-seq
MIRT799738	hsa-miR-4760-5p	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799740	hsa-miR-518a-5p	CLIP-seq
MIRT799741	hsa-miR-527	CLIP-seq
MIRT799742	hsa-miR-544	CLIP-seq
MIRT1936262	hsa-miR-548b-3p	CLIP-seq
MIRT799743	hsa-miR-570	CLIP-seq
MIRT799752	hsa-miR-583	CLIP-seq
MIRT799745	hsa-miR-888	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq
MIRT799747	hsa-miR-92a	CLIP-seq
MIRT799748	hsa-miR-92b	CLIP-seq
MIRT799723	hsa-miR-25	CLIP-seq
MIRT799725	hsa-miR-32	CLIP-seq
MIRT799727	hsa-miR-363	CLIP-seq
MIRT799728	hsa-miR-367	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799740	hsa-miR-518a-5p	CLIP-seq
MIRT799741	hsa-miR-527	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq
MIRT799747	hsa-miR-92a	CLIP-seq
MIRT799748	hsa-miR-92b	CLIP-seq
MIRT1936255	hsa-miR-188-5p	CLIP-seq
MIRT1936257	hsa-miR-3653	CLIP-seq
MIRT1936258	hsa-miR-3658	CLIP-seq
MIRT1936259	hsa-miR-4511	CLIP-seq
MIRT2444021	hsa-miR-4709-3p	CLIP-seq
MIRT1936262	hsa-miR-548b-3p	CLIP-seq
MIRT799721	hsa-miR-2052	CLIP-seq
MIRT799722	hsa-miR-217	CLIP-seq
MIRT799723	hsa-miR-25	CLIP-seq
MIRT799725	hsa-miR-32	CLIP-seq
MIRT799726	hsa-miR-3545-3p	CLIP-seq
MIRT799727	hsa-miR-363	CLIP-seq
MIRT799728	hsa-miR-367	CLIP-seq
MIRT799729	hsa-miR-3671	CLIP-seq
MIRT799750	hsa-miR-3978	CLIP-seq
MIRT799730	hsa-miR-4266	CLIP-seq
MIRT799731	hsa-miR-4433	CLIP-seq
MIRT799732	hsa-miR-4453	CLIP-seq
MIRT799735	hsa-miR-4538	CLIP-seq
MIRT799736	hsa-miR-4680-5p	CLIP-seq
MIRT799737	hsa-miR-4700-3p	CLIP-seq
MIRT799738	hsa-miR-4760-5p	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799740	hsa-miR-518a-5p	CLIP-seq
MIRT799741	hsa-miR-527	CLIP-seq
MIRT799743	hsa-miR-570	CLIP-seq
MIRT799745	hsa-miR-888	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq
MIRT799747	hsa-miR-92a	CLIP-seq
MIRT799748	hsa-miR-92b	CLIP-seq
MIRT799721	hsa-miR-2052	CLIP-seq
MIRT799722	hsa-miR-217	CLIP-seq
MIRT799726	hsa-miR-3545-3p	CLIP-seq
MIRT799729	hsa-miR-3671	CLIP-seq
MIRT799730	hsa-miR-4266	CLIP-seq
MIRT799731	hsa-miR-4433	CLIP-seq
MIRT799736	hsa-miR-4680-5p	CLIP-seq
MIRT799737	hsa-miR-4700-3p	CLIP-seq
MIRT799738	hsa-miR-4760-5p	CLIP-seq
MIRT799739	hsa-miR-4772-3p	CLIP-seq
MIRT799743	hsa-miR-570	CLIP-seq
MIRT799745	hsa-miR-888	CLIP-seq
MIRT799746	hsa-miR-891b	CLIP-seq

Show/Hide all (45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005200	Function	Structural constituent of cytoskeleton	IBA
GO:0005200	Function	Structural constituent of cytoskeleton	IDA	11741539
GO:0005200	Function	Structural constituent of cytoskeleton	TAS	9230079
GO:0005515	Function	Protein binding	IPI	11162547, 12473693, 16027158, 17350576, 24132237, 32911434
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005885	Component	Arp2/3 protein complex	IBA
GO:0005885	Component	Arp2/3 protein complex	IDA	11741539
GO:0005885	Component	Arp2/3 protein complex	IEA
GO:0005885	Component	Arp2/3 protein complex	TAS	9230079
GO:0005886	Component	Plasma membrane	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IEA
GO:0010592	Process	Positive regulation of lamellipodium assembly	IMP	18560548
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0015629	Component	Actin cytoskeleton	TAS	9230079
GO:0030027	Component	Lamellipodium	IDA	9230079
GO:0030041	Process	Actin filament polymerization	IEA
GO:0030672	Component	Synaptic vesicle membrane	IEA
GO:0030838	Process	Positive regulation of actin filament polymerization	IEA
GO:0031252	Component	Cell leading edge	IEA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IBA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IDA	11741539
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IEA
GO:0035861	Component	Site of double-strand break	ISS
GO:0036195	Component	Muscle cell projection membrane	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0044089	Process	Positive regulation of cellular component biogenesis	IEA
GO:0045202	Component	Synapse	IEA
GO:0045202	Component	Synapse	IEA
GO:0051015	Function	Actin filament binding	IDA	11741539
GO:0051130	Process	Positive regulation of cellular component organization	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0070358	Process	Actin polymerization-dependent cell motility	TAS	9230079
GO:0098793	Component	Presynapse	IEA
GO:0098794	Component	Postsynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IEA

MIM	HGNC	e!Ensembl
604224	705	ENSG00000163466

O15144

Protein name

Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)

Protein function

Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks

PDB

6UHC , 6YW6 , 6YW7 , 8P94

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04045	P34-Arc	57 → 284	Arp2/3 complex, 34 kD subunit p34-Arc	Family

Sequence

MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS
LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC
FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV
FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT
INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR

Sequence length

300

Interactions

View interactions

	KEGG		Reactome
	Endocytosis Tight junction Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Bacterial invasion of epithelial cells Pathogenic Escherichia coli infection Shigellosis Salmonella infection Yersinia infection		Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (19)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Cervical cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHOLELITHIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC LEFT-SIDED ULCERATIVE COLITIS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLITIS, ULCERATIVE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GALLSTONES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	Disgenet, GWAS catalog Disgenet, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (21)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Carcinoma	Breast Carcinoma	BEFREE	30720048, 31002363		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	31002363	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	31002363	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33960941	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	31571309		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	25107436	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34938284	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	LHGDN	18708039		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	LHGDN	18836448		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	30720048, 31002363		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	28694563		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28694563, 31571309		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	31571309		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	19332774	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28694563, 31002363		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	28694563		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	28694563	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Transitional cell carcinoma of bladder	Bladder carcinoma	BEFREE	29593429		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	18836448, 19861958		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ulcerative Colitis	Ulcerative colitis	LHGDN	18836448		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ulcerative Colitis	Ulcerative colitis	CTD_human_DG	18836448		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ARPC2 (actin related protein 2/3 complex subunit 2)