CHURC1-FNTB (CHURC1-FNTB readthrough)

Gene

• Entrez ID: 100529261
• Gene name: CHURC1-FNTB readthrough
• Gene symbol: CHURC1-FNTB
• Synonyms (NCBI Gene): FNTB, FTase-beta
• Chromosome: 14
• Chromosome location: 14q23.3
• Summary: This locus represents naturally occurring read-through transcription between the neighboring CHURC1 (churchill domain containing 1) and FNTB (farnesyltransferase, CAAX box, beta) on chromosome 14. The read-through transcript produces a fusion protein that

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT893141	hsa-miR-1304	CLIP-seq
MIRT893142	hsa-miR-1321	CLIP-seq
MIRT893143	hsa-miR-185	CLIP-seq
MIRT893144	hsa-miR-186	CLIP-seq
MIRT893145	hsa-miR-1914	CLIP-seq
MIRT893146	hsa-miR-214	CLIP-seq
MIRT893147	hsa-miR-3064-5p	CLIP-seq
MIRT893148	hsa-miR-3135b	CLIP-seq
MIRT893149	hsa-miR-3162-5p	CLIP-seq
MIRT893150	hsa-miR-3190	CLIP-seq
MIRT893151	hsa-miR-361-3p	CLIP-seq
MIRT893152	hsa-miR-3619-5p	CLIP-seq
MIRT893153	hsa-miR-3652	CLIP-seq
MIRT893154	hsa-miR-3911	CLIP-seq
MIRT893155	hsa-miR-3934	CLIP-seq
MIRT893156	hsa-miR-3978	CLIP-seq
MIRT893157	hsa-miR-4257	CLIP-seq
MIRT893158	hsa-miR-4291	CLIP-seq
MIRT893159	hsa-miR-4306	CLIP-seq
MIRT893160	hsa-miR-4312	CLIP-seq
MIRT893161	hsa-miR-4430	CLIP-seq
MIRT893162	hsa-miR-4481	CLIP-seq
MIRT893163	hsa-miR-4487	CLIP-seq
MIRT893164	hsa-miR-4505	CLIP-seq
MIRT893165	hsa-miR-4519	CLIP-seq
MIRT893166	hsa-miR-4529-5p	CLIP-seq
MIRT893167	hsa-miR-4644	CLIP-seq
MIRT893168	hsa-miR-4662a-3p	CLIP-seq
MIRT893169	hsa-miR-4677-3p	CLIP-seq
MIRT893170	hsa-miR-4739	CLIP-seq
MIRT893171	hsa-miR-4745-5p	CLIP-seq
MIRT893172	hsa-miR-4756-5p	CLIP-seq
MIRT893173	hsa-miR-4782-5p	CLIP-seq
MIRT893174	hsa-miR-5096	CLIP-seq
MIRT893175	hsa-miR-514	CLIP-seq
MIRT893176	hsa-miR-514b-3p	CLIP-seq
MIRT893177	hsa-miR-552	CLIP-seq
MIRT893178	hsa-miR-7	CLIP-seq
MIRT893179	hsa-miR-760	CLIP-seq
MIRT893180	hsa-miR-761	CLIP-seq
MIRT893181	hsa-miR-922	CLIP-seq
MIRT1964733	hsa-miR-1226	CLIP-seq
MIRT1964734	hsa-miR-199a-5p	CLIP-seq
MIRT1964735	hsa-miR-199b-5p	CLIP-seq
MIRT893150	hsa-miR-3190	CLIP-seq
MIRT1964736	hsa-miR-371-3p	CLIP-seq
MIRT1964737	hsa-miR-371b-3p	CLIP-seq
MIRT1964738	hsa-miR-3975	CLIP-seq
MIRT1964739	hsa-miR-432	CLIP-seq
MIRT1964740	hsa-miR-4797-5p	CLIP-seq
MIRT1964741	hsa-miR-515-3p	CLIP-seq
MIRT1964742	hsa-miR-515-5p	CLIP-seq
MIRT1964743	hsa-miR-519e	CLIP-seq
MIRT1964744	hsa-miR-548v	CLIP-seq
MIRT1964745	hsa-miR-766	CLIP-seq
MIRT2200791	hsa-miR-3545-3p	CLIP-seq
MIRT2200792	hsa-miR-3692	CLIP-seq
MIRT2200793	hsa-miR-4436b-5p	CLIP-seq
MIRT2200794	hsa-miR-1827	CLIP-seq
MIRT1964739	hsa-miR-432	CLIP-seq
MIRT2503544	hsa-miR-103a	CLIP-seq
MIRT2503545	hsa-miR-107	CLIP-seq
MIRT2503546	hsa-miR-1224-3p	CLIP-seq
MIRT1964733	hsa-miR-1226	CLIP-seq
MIRT2503547	hsa-miR-1228	CLIP-seq
MIRT2503548	hsa-miR-1252	CLIP-seq
MIRT2503549	hsa-miR-1264	CLIP-seq
MIRT2503550	hsa-miR-15a	CLIP-seq
MIRT2503551	hsa-miR-15b	CLIP-seq
MIRT2503552	hsa-miR-16	CLIP-seq
MIRT893144	hsa-miR-186	CLIP-seq
MIRT2503553	hsa-miR-195	CLIP-seq
MIRT2503554	hsa-miR-197	CLIP-seq
MIRT1964734	hsa-miR-199a-5p	CLIP-seq
MIRT1964735	hsa-miR-199b-5p	CLIP-seq
MIRT2503555	hsa-miR-204	CLIP-seq
MIRT2503556	hsa-miR-211	CLIP-seq
MIRT2503557	hsa-miR-2117	CLIP-seq
MIRT2503558	hsa-miR-224	CLIP-seq
MIRT2503559	hsa-miR-2467-3p	CLIP-seq
MIRT893150	hsa-miR-3190	CLIP-seq
MIRT2200791	hsa-miR-3545-3p	CLIP-seq
MIRT2503560	hsa-miR-3685	CLIP-seq
MIRT2200792	hsa-miR-3692	CLIP-seq
MIRT1964736	hsa-miR-371-3p	CLIP-seq
MIRT1964737	hsa-miR-371b-3p	CLIP-seq
MIRT2503561	hsa-miR-384	CLIP-seq
MIRT893154	hsa-miR-3911	CLIP-seq
MIRT893155	hsa-miR-3934	CLIP-seq
MIRT2503562	hsa-miR-3944-5p	CLIP-seq
MIRT1964738	hsa-miR-3975	CLIP-seq
MIRT893156	hsa-miR-3978	CLIP-seq
MIRT2503563	hsa-miR-424	CLIP-seq
MIRT2503564	hsa-miR-4252	CLIP-seq
MIRT2503565	hsa-miR-4267	CLIP-seq
MIRT2503566	hsa-miR-4273	CLIP-seq
MIRT2503567	hsa-miR-4283	CLIP-seq
MIRT2503568	hsa-miR-4286	CLIP-seq
MIRT2503569	hsa-miR-4302	CLIP-seq
MIRT2503570	hsa-miR-431	CLIP-seq
MIRT2503571	hsa-miR-4428	CLIP-seq
MIRT2200793	hsa-miR-4436b-5p	CLIP-seq
MIRT2503572	hsa-miR-4437	CLIP-seq
MIRT2503573	hsa-miR-4446-5p	CLIP-seq
MIRT2503574	hsa-miR-4486	CLIP-seq
MIRT2503575	hsa-miR-4489	CLIP-seq
MIRT2503576	hsa-miR-4524	CLIP-seq
MIRT2503577	hsa-miR-4656	CLIP-seq
MIRT2503578	hsa-miR-4676-5p	CLIP-seq
MIRT2503579	hsa-miR-4683	CLIP-seq
MIRT2503580	hsa-miR-4691-3p	CLIP-seq
MIRT2503581	hsa-miR-4711-3p	CLIP-seq
MIRT2503582	hsa-miR-4715-3p	CLIP-seq
MIRT2503583	hsa-miR-4755-3p	CLIP-seq
MIRT2503584	hsa-miR-4755-5p	CLIP-seq
MIRT2503585	hsa-miR-4768-5p	CLIP-seq
MIRT1964740	hsa-miR-4797-5p	CLIP-seq
MIRT2503586	hsa-miR-497	CLIP-seq
MIRT2503587	hsa-miR-503	CLIP-seq
MIRT1964741	hsa-miR-515-3p	CLIP-seq
MIRT1964742	hsa-miR-515-5p	CLIP-seq
MIRT1964743	hsa-miR-519e	CLIP-seq
MIRT2503588	hsa-miR-539	CLIP-seq
MIRT2503589	hsa-miR-548aa	CLIP-seq
MIRT1964744	hsa-miR-548v	CLIP-seq
MIRT893177	hsa-miR-552	CLIP-seq
MIRT2503590	hsa-miR-575	CLIP-seq
MIRT2503591	hsa-miR-623	CLIP-seq
MIRT2503592	hsa-miR-646	CLIP-seq
MIRT2503593	hsa-miR-711	CLIP-seq
MIRT1964745	hsa-miR-766	CLIP-seq
MIRT2503594	hsa-miR-892a	CLIP-seq
MIRT893181	hsa-miR-922	CLIP-seq
MIRT2503544	hsa-miR-103a	CLIP-seq
MIRT2503545	hsa-miR-107	CLIP-seq
MIRT1964733	hsa-miR-1226	CLIP-seq
MIRT2503550	hsa-miR-15a	CLIP-seq
MIRT2503551	hsa-miR-15b	CLIP-seq
MIRT2503552	hsa-miR-16	CLIP-seq
MIRT893144	hsa-miR-186	CLIP-seq
MIRT2678204	hsa-miR-1912	CLIP-seq
MIRT2503553	hsa-miR-195	CLIP-seq
MIRT1964734	hsa-miR-199a-5p	CLIP-seq
MIRT1964735	hsa-miR-199b-5p	CLIP-seq
MIRT2503557	hsa-miR-2117	CLIP-seq
MIRT2503558	hsa-miR-224	CLIP-seq
MIRT2503559	hsa-miR-2467-3p	CLIP-seq
MIRT893150	hsa-miR-3190	CLIP-seq
MIRT2200791	hsa-miR-3545-3p	CLIP-seq
MIRT2503560	hsa-miR-3685	CLIP-seq
MIRT2200792	hsa-miR-3692	CLIP-seq
MIRT1964736	hsa-miR-371-3p	CLIP-seq
MIRT1964737	hsa-miR-371b-3p	CLIP-seq
MIRT2503561	hsa-miR-384	CLIP-seq
MIRT893154	hsa-miR-3911	CLIP-seq
MIRT893155	hsa-miR-3934	CLIP-seq
MIRT2503562	hsa-miR-3944-5p	CLIP-seq
MIRT1964738	hsa-miR-3975	CLIP-seq
MIRT893156	hsa-miR-3978	CLIP-seq
MIRT2503563	hsa-miR-424	CLIP-seq
MIRT2503564	hsa-miR-4252	CLIP-seq
MIRT2503566	hsa-miR-4273	CLIP-seq
MIRT2503569	hsa-miR-4302	CLIP-seq
MIRT2200793	hsa-miR-4436b-5p	CLIP-seq
MIRT2503572	hsa-miR-4437	CLIP-seq
MIRT2503574	hsa-miR-4486	CLIP-seq
MIRT2503576	hsa-miR-4524	CLIP-seq
MIRT2503578	hsa-miR-4676-5p	CLIP-seq
MIRT2503580	hsa-miR-4691-3p	CLIP-seq
MIRT2503582	hsa-miR-4715-3p	CLIP-seq
MIRT2503583	hsa-miR-4755-3p	CLIP-seq
MIRT1964740	hsa-miR-4797-5p	CLIP-seq
MIRT2503586	hsa-miR-497	CLIP-seq
MIRT2503587	hsa-miR-503	CLIP-seq
MIRT1964741	hsa-miR-515-3p	CLIP-seq
MIRT1964742	hsa-miR-515-5p	CLIP-seq
MIRT1964743	hsa-miR-519e	CLIP-seq
MIRT2503588	hsa-miR-539	CLIP-seq
MIRT2503589	hsa-miR-548aa	CLIP-seq
MIRT1964744	hsa-miR-548v	CLIP-seq
MIRT893177	hsa-miR-552	CLIP-seq
MIRT2503590	hsa-miR-575	CLIP-seq
MIRT2503592	hsa-miR-646	CLIP-seq
MIRT2503593	hsa-miR-711	CLIP-seq
MIRT2503594	hsa-miR-892a	CLIP-seq
MIRT893181	hsa-miR-922	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Interactions View interactions

Pathways

KEGG:

Terpenoid backbone biosynthesis

Reactome:

Inactivation, recovery and regulation of the phototransduction cascade

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
LUNG ADENOCARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Colonic Neoplasms	Colonic neoplasm	Pubtator	35167937	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	35167937	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	29574663		★☆☆☆☆ Found in Text Mining only