ARMCX5-GPRASP2 (ARMCX5-GPRASP2 readthrough)

Gene

• Entrez ID: 100528062
• Gene name: ARMCX5-GPRASP2 readthrough
• Gene symbol: ARMCX5-GPRASP2
• Synonyms (NCBI Gene): ARMCX5-GPRASP2-BHLHB9-LINC00630, GPRASP3, bHLHb9, p60TRP
• Chromosome: X
• Chromosome location: Xq22.1
• Summary: This locus represents naturally occurring readthrough transcription among the adjacent armadillo repeat containing, X-linked 5 (ARMCX5), G protein-coupled receptor associated sorting proteins 1 and 2 (GPRASP1 and GPRASP2), basic helix-loop-helix family me

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT799395	hsa-miR-1271	CLIP-seq
MIRT799396	hsa-miR-182	CLIP-seq
MIRT799397	hsa-miR-3065-5p	CLIP-seq
MIRT799398	hsa-miR-3120-3p	CLIP-seq
MIRT799399	hsa-miR-3662	CLIP-seq
MIRT799400	hsa-miR-378	CLIP-seq
MIRT799401	hsa-miR-378b	CLIP-seq
MIRT799402	hsa-miR-378c	CLIP-seq
MIRT799403	hsa-miR-378d	CLIP-seq
MIRT799404	hsa-miR-378e	CLIP-seq
MIRT799405	hsa-miR-378f	CLIP-seq
MIRT799406	hsa-miR-378h	CLIP-seq
MIRT799407	hsa-miR-378i	CLIP-seq
MIRT799408	hsa-miR-422a	CLIP-seq
MIRT799409	hsa-miR-451b	CLIP-seq
MIRT799410	hsa-miR-4520a-3p	CLIP-seq
MIRT799411	hsa-miR-4638-3p	CLIP-seq
MIRT799412	hsa-miR-4642	CLIP-seq
MIRT799413	hsa-miR-4696	CLIP-seq
MIRT799414	hsa-miR-4698	CLIP-seq
MIRT799415	hsa-miR-579	CLIP-seq
MIRT799416	hsa-miR-640	CLIP-seq
MIRT799417	hsa-miR-96	CLIP-seq
MIRT2479402	hsa-miR-200b	CLIP-seq
MIRT2479403	hsa-miR-200c	CLIP-seq
MIRT799398	hsa-miR-3120-3p	CLIP-seq
MIRT2479404	hsa-miR-374c	CLIP-seq
MIRT799400	hsa-miR-378	CLIP-seq
MIRT799401	hsa-miR-378b	CLIP-seq
MIRT799402	hsa-miR-378c	CLIP-seq
MIRT799403	hsa-miR-378d	CLIP-seq
MIRT799404	hsa-miR-378e	CLIP-seq
MIRT799405	hsa-miR-378f	CLIP-seq
MIRT799406	hsa-miR-378h	CLIP-seq
MIRT799407	hsa-miR-378i	CLIP-seq
MIRT799408	hsa-miR-422a	CLIP-seq
MIRT2479405	hsa-miR-429	CLIP-seq
MIRT799409	hsa-miR-451b	CLIP-seq
MIRT799410	hsa-miR-4520a-3p	CLIP-seq
MIRT799411	hsa-miR-4638-3p	CLIP-seq
MIRT799413	hsa-miR-4696	CLIP-seq
MIRT2479406	hsa-miR-4724-5p	CLIP-seq
MIRT2479407	hsa-miR-570	CLIP-seq
MIRT2479408	hsa-miR-642b	CLIP-seq
MIRT2479409	hsa-miR-655	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001540	Function	Amyloid-beta binding	IEA
GO:0001664	Function	G protein-coupled receptor binding	IBA
GO:0001664	Function	G protein-coupled receptor binding	IDA	15086532
GO:0005515	Function	Protein binding	IPI	15383276, 21988832, 25416956, 25910212, 26871637, 27107012, 28514442, 31515488, 32296183, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15302935
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0007611	Process	Learning or memory	IEA
GO:0007611	Process	Learning or memory	ISS
GO:0042803	Function	Protein homodimerization activity	IEA
GO:0042803	Function	Protein homodimerization activity	ISS
GO:0043524	Process	Negative regulation of neuron apoptotic process	IEA
GO:0043524	Process	Negative regulation of neuron apoptotic process	ISS
GO:0050769	Process	Positive regulation of neurogenesis	IEA
GO:0050769	Process	Positive regulation of neurogenesis	ISS
GO:0051965	Process	Positive regulation of synapse assembly	IEA
GO:0051965	Process	Positive regulation of synapse assembly	ISS
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	IEA
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	ISS
GO:0061484	Process	Hematopoietic stem cell homeostasis	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ARMCX5-GPRASP2-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, X-LINKED 7	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DISABILITY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Malignant Neoplasms	Malignant Neoplasm	BEFREE	26854063		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	23345134		★☆☆☆☆ Found in Text Mining only