RPL17-C18orf32 (RPL17-C18orf32 readthrough)

Gene

• Entrez ID: 100526842
• Gene name: RPL17-C18orf32 readthrough
• Gene symbol: RPL17-C18orf32
• Synonyms (NCBI Gene): PD-1, RPL17
• Chromosome: 18
• Chromosome location: 18q21.1
• Summary: This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT571733	hsa-miR-3609	PAR-CLIP	20371350
MIRT571732	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571731	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571730	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571729	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571728	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571727	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571726	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571725	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571724	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571723	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT290603	hsa-miR-4803	PAR-CLIP	20371350
MIRT571722	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT571721	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT571720	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT571719	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT571718	hsa-miR-302e	PAR-CLIP	20371350
MIRT571717	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT571716	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT571715	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT571714	hsa-miR-520b	PAR-CLIP	20371350
MIRT571713	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT571712	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT571711	hsa-miR-520e	PAR-CLIP	20371350
MIRT571710	hsa-miR-802	PAR-CLIP	20371350
MIRT571709	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT571708	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT571706	hsa-miR-8075	PAR-CLIP	20371350
MIRT571733	hsa-miR-3609	PAR-CLIP	20371350
MIRT571732	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571731	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571730	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571729	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571728	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571727	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571726	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571725	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571724	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571723	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT290603	hsa-miR-4803	PAR-CLIP	20371350
MIRT571722	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT571721	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT571720	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT571719	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT571718	hsa-miR-302e	PAR-CLIP	20371350
MIRT571717	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT571716	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT571715	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT571714	hsa-miR-520b	PAR-CLIP	20371350
MIRT571713	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT571712	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT571711	hsa-miR-520e	PAR-CLIP	20371350
MIRT571710	hsa-miR-802	PAR-CLIP	20371350
MIRT571709	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT571708	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT571706	hsa-miR-8075	PAR-CLIP	20371350
MIRT571733	hsa-miR-3609	PAR-CLIP	20371350
MIRT571732	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571731	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571730	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571729	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571728	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571727	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571726	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571725	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571724	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571723	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT290603	hsa-miR-4803	PAR-CLIP	20371350
MIRT571722	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT571721	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT571720	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT571719	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT571718	hsa-miR-302e	PAR-CLIP	20371350
MIRT571717	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT571716	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT571715	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT571714	hsa-miR-520b	PAR-CLIP	20371350
MIRT571713	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT571712	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT571711	hsa-miR-520e	PAR-CLIP	20371350
MIRT571710	hsa-miR-802	PAR-CLIP	20371350
MIRT571709	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT571708	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT571706	hsa-miR-8075	PAR-CLIP	20371350
MIRT571733	hsa-miR-3609	PAR-CLIP	20371350
MIRT571732	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571731	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571730	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571729	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571728	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571727	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571726	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571725	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571724	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571723	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT290603	hsa-miR-4803	PAR-CLIP	20371350
MIRT571722	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT571721	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT571720	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT571719	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT571718	hsa-miR-302e	PAR-CLIP	20371350
MIRT571717	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT571716	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT571715	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT571714	hsa-miR-520b	PAR-CLIP	20371350
MIRT571713	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT571712	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT571711	hsa-miR-520e	PAR-CLIP	20371350
MIRT571710	hsa-miR-802	PAR-CLIP	20371350
MIRT571709	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT571708	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT571706	hsa-miR-8075	PAR-CLIP	20371350

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Interactions View interactions

Pathways

KEGG:

Ribosome
Coronavirus disease - COVID-19

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANEMIA, MACROCYTIC	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL EPICANTHUS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 25	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCYTOPENIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	26081225		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	31718573		★☆☆☆☆ Found in Text Mining only
Adult T-Cell Lymphoma/Leukemia	T-Cell Lymphoma/Leukemia	BEFREE	23888327		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	26650044	Inhibit	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	37438770, 37545529	Associate	★☆☆☆☆ Found in Text Mining only
Ankylosing spondylitis	Ankylosing Spondylitis	BEFREE	25432079, 26232179		★☆☆☆☆ Found in Text Mining only
Aplastic Anemia	Aplastic anemia	BEFREE	23373967		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	15912506, 20178125, 27660198		★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	28115358		★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	28535114		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	21487727, 29921237, 30546434		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	34732136	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	28446615, 30173128		★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	27836206		★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	34871464	Associate	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	35712285	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30334238		★☆☆☆☆ Found in Text Mining only
Connective Tissue Diseases	Connective Tissue Disease	BEFREE	22274654		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	27491898, 28807336		★☆☆☆☆ Found in Text Mining only
Cutaneous Mastocytosis	Cutaneous mastocytosis	BEFREE	23267208		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	30103068		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	14617032, 16978382, 17203303		★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	28717645		★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	28717645	Associate	★☆☆☆☆ Found in Text Mining only
Eclampsia	Eclampsia	BEFREE	29265516		★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	26181000		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	27836206		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	28848143		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	28848143		★☆☆☆☆ Found in Text Mining only
Focal glomerulosclerosis	Glomerulosclerosis	BEFREE	28158993		★☆☆☆☆ Found in Text Mining only
Focal Segmental Glomerulosclerosis, Not Otherwise Specified	Focal segmental glomerulosclerosis	BEFREE	28158993		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Neoplasms	Gastrointestinal Neoplasms	BEFREE	30510858		★☆☆☆☆ Found in Text Mining only
Giant Cell Arteritis	Giant Cell Arteritis	BEFREE	28115719		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	31661771		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	31661771		★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	30622541		★☆☆☆☆ Found in Text Mining only
Graves Disease	Graves Disease	BEFREE	28284988		★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	30206415	Associate	★☆☆☆☆ Found in Text Mining only
Immune System Diseases	Immune System Diseases	BEFREE	29345058		★☆☆☆☆ Found in Text Mining only
Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	BEFREE	19931185		★☆☆☆☆ Found in Text Mining only
Intervertebral Disc Degeneration	Intervertebral disc disease	Pubtator	31124977	Associate	★☆☆☆☆ Found in Text Mining only
Invasive Ductal Breast Carcinoma	Invasive Duct and Lobular Carcinoma	BEFREE	30085937		★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney Disease	BEFREE	15352422		★☆☆☆☆ Found in Text Mining only
Leukemia, T-Cell	T-cell leukemia	BEFREE	23888327		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	29967316		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus	Lupus Erythematosus	BEFREE	15352422		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Discoid	Lupus Erythematosus	BEFREE	15352422		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	15022318, 15352422, 19116915, 20178125, 31565862		★☆☆☆☆ Found in Text Mining only
Lupus Vulgaris	Lupus Vulgaris	BEFREE	15352422		★☆☆☆☆ Found in Text Mining only
Macular dystrophy, corneal type 1	Macular corneal dystrophy	BEFREE	28158993		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	21487727, 29921237, 30546434		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	26181000		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	28848143		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of kidney	Kidney Cancer	BEFREE	31015307		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	28446615, 30173128		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27196778, 27557786, 28281549, 28402953, 28409437, 28716069, 29147618, 29556232, 30178256, 30249505, 30521597, 30622541, 30786013, 31683962, 31733578		★☆☆☆☆ Found in Text Mining only
Mastocytosis	Mastocytosis	BEFREE	23267208		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	20948441, 28363614, 28716069, 8579579		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	30103068		★☆☆☆☆ Found in Text Mining only
Mucocutaneous Lymph Node Syndrome	Kawasaki disease	BEFREE	19468750		★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	28461396		★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	CTD_human_DG	16214533		★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial ischemia	Pubtator	40620566	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20428207, 24764579, 25539810, 26181000, 26833127, 27207108, 27491898, 27894751, 28265006, 28913723, 29143824, 29153625, 29167175, 29222272, 29598887, 30368118, 30617136, 30655605, 30886151, 31240875, 31310752, 31703637		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	27485075, 28293123, 29658848, 30249170, 30765392, 30769852		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	23354626	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	31694582		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	30315241		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	27491898, 28807336		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	15022318, 28791012		★☆☆☆☆ Found in Text Mining only
Sarcoidosis	Sarcoidosis	BEFREE	27564547		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	28688724, 29220291		★☆☆☆☆ Found in Text Mining only
Secondary malignant neoplasm of colon and/or rectum	Colorectal Neoplasms	BEFREE	31788079		★☆☆☆☆ Found in Text Mining only
Septicemia	Septicemia	BEFREE	29049359, 29345058		★☆☆☆☆ Found in Text Mining only
Small cell carcinoma of lung	Lung carcinoma	BEFREE	29776963		★☆☆☆☆ Found in Text Mining only
Spondylitis Ankylosing	Ankylosing spondylitis	Pubtator	34521416	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	29548299, 31562203		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	27097946	Associate	★☆☆☆☆ Found in Text Mining only
T-Cell Lymphoma	T-Cell Lymphoma	BEFREE	29143824		★☆☆☆☆ Found in Text Mining only
Takayasu Arteritis	Takayasu Arteritis	BEFREE	22274654		★☆☆☆☆ Found in Text Mining only
Thymic Carcinoma	Thymic Carcinoma	BEFREE	31639039		★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	28754129	Associate	★☆☆☆☆ Found in Text Mining only
Vasculitis	Vasculitis	BEFREE	22274654		★☆☆☆☆ Found in Text Mining only