Gene Gene information from NCBI Gene database.
Entrez ID 100506736
Gene name Schlafen family member 12 like
Gene symbol SLFN12L
Synonyms (NCBI Gene)
-
Chromosome 17
Chromosome location 17q12
miRNA miRNA information provided by mirtarbase database.
463
miRTarBase ID miRNA Experiments Reference
MIRT461411 hsa-miR-4695-5p HITS-CLIP 23706177
MIRT461410 hsa-miR-1910-3p HITS-CLIP 23706177
MIRT461409 hsa-miR-6511a-5p HITS-CLIP 23706177
MIRT461405 hsa-miR-3174 HITS-CLIP 23706177
MIRT461404 hsa-miR-4257 HITS-CLIP 23706177
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0004540 Function RNA nuclease activity IEA
GO:0016020 Component Membrane IEA
GO:0016075 Process RRNA catabolic process IEA
GO:0043022 Function Ribosome binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614956 33920 ENSG00000205045
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6IEE8
Protein name Schlafen family member 12-like
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04326 AlbA_2 218 349 Putative DNA-binding domain Domain
Sequence
MDLARKEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNE
NVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNY
FHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEF
PAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEIL
PQYVSAFANTDGGYLFVGLNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGT
INYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQ
LTEKEWIQFMV
DSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFS
QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV
QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES
YYWTTAQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWFVCFFLR
Sequence length 588
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Colon adenocarcinoma Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DUCHENNE MUSCULAR DYSTROPHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Stomach Neoplasms Stomach neoplasms Pubtator 36090985 Stimulate
★☆☆☆☆
Found in Text Mining only