SPMAP2L (sperm microtubule associated protein 2 like)

Gene Gene information from NCBI Gene database.
Gene Other IDs Protein Associated diseases
Entrez ID 100506564
Gene name Sperm microtubule associated protein 2 like
Gene symbol SPMAP2L
Synonyms (NCBI Gene)
THEGL
Chromosome 4
Chromosome location 4q12
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P0DJG4
Protein name Sperm microtubule associated protein 2-like (Testicular haploid expressed gene protein-like) (Theg spermatid-like protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14912 THEG 202 → 277 Testicular haploid expressed repeat Repeat
PF14912 THEG 296 → 350 Testicular haploid expressed repeat Repeat
PF14912 THEG 367 → 403 Testicular haploid expressed repeat Repeat
PF14912 THEG 404 → 463 Testicular haploid expressed repeat Repeat
Sequence 
MENQEFLSSSAPSEVTDGQVSTEISTCSEVFQKPIVLRILDTHRELEESEDPEKHENPEE
PEEVREQDQRDESEECDEPHESYEPHAPYAPHKPRDSYAPYELHGPHAAPKLLKAREPRQ
LRHTREPRKSREAKETELLPSAAVMISPSLITRAPPRPQLSFLGANPVSCDFVRKCFSSR
KRTPNLSKPKKQWGTPDRKLFWGNQDPIRPVSQGALKAQLTKRLENLAQPKEVSCHYVPN
RAQYYHSCGRESVIWEITPPALFRQPSKRIQRLSQPNGFKRQCLLNRPFSDNSARDSLRI
SDPSPRILQLSVAKGTDPNYHPSKKMQTKISLSTLSAIATPRIIELAHPRIKLEGLCYER
QRSELPIRPVPPAAMIAKPSPRTIALAKSKSVHQDYLPDRDAHWPVSYATTHSKASPRIQ
ELANPNKRAPVRIVYYDPDVFKTKPAALKAQCSQRIWELSQPLTR
Sequence length 465
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Gene Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (3)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
THYROID CANCER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
THYROID CARCINOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations